A city skyline with high-rise buildings and a bridge over a body of water.

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Check availability on Otay Mesa Gay-Friendly Hotels

Next weekend
13 Nov - 15 Nov
In two weeks
20 Nov - 22 Nov

Our top choices for Otay Mesa LGBT-friendly hotels

A modern interior with a long table and blue chairs, large windows with a view of palm trees and parked vehicles outside.

1. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.4 out of 10, Very good, (1,960 reviews)
"Good place to stay for work."
United States
Renato
The price is Rp2.351.570
Rp2.674.911 total
includes taxes & fees
6 Dec - 7 Dec
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
A buffet with various food items, including omelets and other dishes, served in metal trays.

2. Holiday Inn Express San Diego South - Chula Vista by IHG

Holiday Inn Express San Diego South - Chula Vista by IHG
2.5 star property
14.5 km from Otay Mesa
9.4 out of 10, Exceptional, (1,652 reviews)
"Great stay"
United States
Daniel
The price is Rp2.803.795
Rp3.084.175 total
includes taxes & fees
6 Dec - 7 Dec
Holiday Inn Express San Diego South - Chula Vista by IHG
An outdoor seating area with fire pit, lounge chairs, and tables, adjacent to a building with large windows and a brick facade.

3. Hampton Inn Chula Vista Eastlake

Hampton Inn Chula Vista Eastlake
2.5 star property
10.4 km from Otay Mesa
9.2 out of 10, Wonderful, (1,001 reviews)
"Everything was great, love this hotel for a quick day trip"
United States
jose
The price is Rp2.951.763
Rp3.252.695 total
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn Chula Vista Eastlake
A breakfast bar with La Quinta branding, a coffee machine, and a waffle display.

4. La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
12.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,795 reviews)
"Clean room , friendly staff , always helpful, breakfast good , always great to return"
United States
Luis
The price is Rp1.875.829
Rp2.063.412 total
includes taxes & fees
22 Nov - 23 Nov
La Quinta Inn by Wyndham San Diego Chula Vista
A spacious lobby with a flat-screen TV, a fireplace, and comfortable seating areas.

5. Residence Inn by Marriott San Diego Chula Vista

Residence Inn by Marriott San Diego Chula Vista
3.0 star property
7.8 km from Otay Mesa
9.4 out of 10, Exceptional, (643 reviews)
"Wonderful accommodations, delicious breakfast, friendly staff, convenient location."
United States
Leslie
The price is Rp3.406.520
Rp3.753.815 total
includes taxes & fees
30 Nov - 1 Dec
Residence Inn by Marriott San Diego Chula Vista
A hotel with a large swimming pool, multiple water slides, and a well-lit outdoor area with lounge chairs and umbrellas.

6. Gaylord Pacific Resort & Convention Center

Gaylord Pacific Resort & Convention Center
4.0 star property
14.4 km from Otay Mesa
8.8 out of 10, Excellent, (703 reviews)
"I had a wonderful stay at the Gaylord! Everything was great, and I have no complaints. The restaurants were excellent, and having Starbucks downstairs was amazing—a perfect way to start the morning. I really enjoyed my visit and would happily stay again!"
United States
Joane
The price is Rp5.064.920
Rp6.596.154 total
includes taxes & fees
29 Nov - 30 Nov
Gaylord Pacific Resort & Convention Center
A swimming pool with palm trees and a mountain in the background.

7. Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
28.5 km from Otay Mesa
9.4 out of 10, Exceptional, (2,215 reviews)
"Great stay!"
United States
Kimberly
The price is Rp1.645.195
Rp2.026.872 total
includes taxes & fees
9 Nov - 10 Nov
Sycuan Casino Resort
Bar (on property)

8. Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (4,228 reviews)
"Great property, friendly staff and a restaurant with good food and live music next door. Had an excellent time!"
United States
Candas
The price is Rp2.425.916
Rp2.673.239 total
includes taxes & fees
29 Nov - 30 Nov
Best Western Plus Marina Gateway Hotel
A balcony with a view of the beach, palm trees, and a parking area.

9. Los Bungalows

Los Bungalows
2.5 star property
15 km from Otay Mesa
8.2 out of 10, Very good, (569 reviews)
"Just a perfect place to stay at absolutely 10/10"
United States
Megan Hillary
The price is Rp2.714.300
Rp3.094.302 total
includes taxes & fees
9 Nov - 10 Nov
Los Bungalows
A spacious lounge area with a sofa, a coffee table, and a bar with stools.

10. Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
24.7 km from Otay Mesa
9.4 out of 10, Exceptional, (1,261 reviews)
"Amazing stay! Would definitely come back!"
United States
Dirosia
The price is Rp2.604.816
Rp3.020.155 total
includes taxes & fees
22 Nov - 23 Nov
Marriott Vacation Club®, San Diego
A hotel room with a large window offering a city view, a bed, a chair, and a small table.

11. The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
25.4 km from Otay Mesa
8.8 out of 10, Excellent, (2,363 reviews)
"Really enjoyed my stay!"
United States
Kelly
The price is Rp2.290.972
Rp2.656.267 total
includes taxes & fees
15 Nov - 16 Nov
The DEXTRO Little Italy, BW Premier Collection
A buffet with various food items, including omelets and baked goods, served in metal containers.

12. Holiday Inn Express San Diego South - National City by IHG

Holiday Inn Express San Diego South - National City by IHG
2.5 star property
16.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,003 reviews)
"It’s clean and ideal"
United States
Cesar
The price is Rp2.369.659
Rp2.611.246 total
includes taxes & fees
6 Dec - 7 Dec
Holiday Inn Express San Diego South - National City by IHG
An outdoor patio with a fire feature, seating, and large windows.

13. Hampton Inn & Suites Imperial Beach San Diego

Hampton Inn & Suites Imperial Beach San Diego
2.5 star property
13.7 km from Otay Mesa
9.4 out of 10, Exceptional, (1,001 reviews)
"Great place to stay in imperial beach. Would stay here again."
United States
Joshua
The price is Rp2.675.363
Rp3.055.131 total
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn & Suites Imperial Beach San Diego
A modern hotel with a courtyard featuring outdoor seating, a chess table, and a well-maintained lawn.

14. Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town

Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town
4.0 star property
30.8 km from Otay Mesa
9.2 out of 10, Wonderful, (1,481 reviews)
"The breakfast was amazing!"
United States
David
The price is Rp2.752.241
Rp3.163.563 total
includes taxes & fees
16 Nov - 17 Nov
Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town
A Marriott hotel with multiple floors, balconies, and a cityscape in the background.

15. San Diego Marriott Gaslamp Quarter

San Diego Marriott Gaslamp Quarter
4.0 star property
Gaslamp Quarter, 24 km from Otay Mesa
8.8 out of 10, Excellent, (1,804 reviews)
"It was a great stay and centrally located."
United States
Tiffany
The price is Rp3.057.041
Rp3.544.540 total
includes taxes & fees
22 Nov - 23 Nov
San Diego Marriott Gaslamp Quarter
A modern living room with large windows, a leather sofa, two armchairs, and a coffee table.

16. Days Inn by Wyndham Chula Vista/San Diego

Days Inn by Wyndham Chula Vista/San Diego
3.0 star property
13.8 km from Otay Mesa
7.0 out of 10, Good, (1,321 reviews)
"Stayed here a few times and staff has always treated me well"
United States
Brian
The price is Rp1.546.609
Rp1.704.363 total
includes taxes & fees
17 Nov - 18 Nov
Days Inn by Wyndham Chula Vista/San Diego
A resort pool area with palm trees, lounge chairs, and a city skyline in the background.

17. Coronado Island Marriott Resort & Spa

Coronado Island Marriott Resort & Spa
4.0 star property
23.5 km from Otay Mesa
8.4 out of 10, Very good, (1,001 reviews)
"Great staff, location, and room was clean and nice."
United States
Keri
The price is Rp4.136.050
Rp5.620.461 total
includes taxes & fees
29 Nov - 30 Nov
Coronado Island Marriott Resort & Spa
A hotel lobby with a waterfall feature, outdoor seating area, and multiple floors with balconies.

18. Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
29.8 km from Otay Mesa
8.4 out of 10, Very good, (1,477 reviews)
"Had a good stay"
United States
Yesenia
The price is Rp2.062.146
Rp2.377.075 total
includes taxes & fees
23 Nov - 24 Nov
Crowne Plaza San Diego - Mission Valley by IHG
A modern interior with a sectional sofa, a glass coffee table, and large windows offering a view of the cityscape.

19. Best Western Plus Bayside Inn

Best Western Plus Bayside Inn
3.0 star property
25.4 km from Otay Mesa
9.0 out of 10, Wonderful, (1,034 reviews)
"Nice spot to stay downtown"
United States
Ricardo
The price is Rp2.595.914
Rp3.004.777 total
includes taxes & fees
22 Nov - 23 Nov
Best Western Plus Bayside Inn
A table with a fire feature, a charcuterie board, and two glasses of wine, overlooking a marina with boats.

20. Bay Club Hotel & Marina

Bay Club Hotel & Marina
3.5 star property
29.2 km from Otay Mesa
9.2 out of 10, Wonderful, (4,061 reviews)
"Beautiful, clean hotel and friendly staff!!"
United States
Robin
The price is Rp2.751.337
Rp3.162.500 total
includes taxes & fees
10 Nov - 11 Nov
Bay Club Hotel & Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Otay Mesa Hotel Reviews

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

10/10 Excellent
"Amazing"
Igor 1-night trip
Posted 12 hours ago
Hyatt Regency Mission Bay Spa and Marina

Frequently asked questions

How do I find gay-friendly accommodation in Otay Mesa?
Consider this your open invitation to pack your bags and find LGBTQ-friendly hotels in Otay Mesa on Expedia. People like Otay Mesa for its shopping and restaurants.
What is the top LGBTQ-friendly hotel in Otay Mesa?
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi.
What should I do while I'm visiting Otay Mesa?
During your trip, get out and enjoy everything Otay Mesa has to offer. You and your travelling companions may want to visit San Diego Zoo, San Ysidro Border Crossing and Petco Park. While you're here, capture some great memories of your trip with stops at Port of San Diego and Marine Corps Recruit Depot.
What is a gay-friendly hotel in Otay Mesa?
LGBTQ-friendly hotels, also known as gay-friendly hotels, welcome all travellers who identify as LGBTQIA+. We have worked with the International Gay and Lesbian Travel Association (IGLTA) to compile a selection of gay-friendly hotels worldwide. In Otay Mesa, hotels affiliated with IGLTA operate in a spirit of inclusiveness, prioritising a diverse environment in which guests are welcomed, respected and not obliged to declare or hide their sexual orientation.
What can I expect from a gay-friendly hotel in Otay Mesa?
Stay at a gay-friendly hotel in Otay Mesa and you won't have to hide or your sexuality or your gender identity when you check in. Some of Expedia's LGBTQ-friendly hotels go the extra mile and offer concierge services that provide information about nearby LGBTQ restaurants and local events.