A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

Search Luxury Hotels in Panama City

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Panama City Luxury Hotels

This weekend
Next weekend

Our top choices for Panama City luxury hotels

1. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (708 reviews)
  • cleanliness
    Indulge in colonial elegance at this Panama City gem featuring a full-service spa, outdoor pool, and gourmet dining.
The price is Rp6.814.206
Rp7.495.627 total
includes taxes & fees
24 Aug - 25 Aug
Sofitel Legend Casco Viejo, Panama City

2. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (335 reviews)
  • cleanliness
    Experience historic luxury in Panama's Casco Viejo district with 5 restaurants and a rooftop pool with spectacular views.
The price is Rp5.975.950
Rp6.573.545 total
includes taxes & fees
24 Aug - 25 Aug
Hotel La Compañía Casco Antiguo

3. JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,003 reviews)
  • cleanliness
    Unwind in opulent waterfront luxury with 4 pristine pools and ocean-view dining in Panama City.
The price is Rp5.750.613
Rp6.325.674 total
includes taxes & fees
5 Sept - 6 Sept
JW Marriott Panama

4. W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,006 reviews)
  • cleanliness
    Lavish urban retreat offers 3 hot tubs, poolside luxury, and concierge services in Panama city.
The price is Rp5.029.533
Rp5.532.486 total
includes taxes & fees
7 Aug - 8 Aug
W Panama

5. Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
4.0 star property
Veracruz
7.6 out of 10, Good, (1,045 reviews)
The price is Rp4.907.851
Rp4.907.851 total
includes taxes & fees
23 Aug - 24 Aug
Dreams Playa Bonita Panama - All Inclusive

6. Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,003 reviews)
  • cleanliness
    Panama City sophistication meets relaxation with an attached winery, poolside dining, and a full-service spa offering couples' treatments.
The price is Rp4.272.038
Rp4.699.242 total
includes taxes & fees
4 Sept - 5 Sept
Hilton Panama

7. Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,002 reviews)
  • cleanliness
    Panama City elegance at this Waldorf Astoria hotel with a full-service spa, outdoor pool, and refined dining in two upscale restaurants.
The price is Rp4.793.019
Rp5.272.357 total
includes taxes & fees
30 Aug - 31 Aug
Waldorf Astoria Panama

8. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (724 reviews)
  • cleanliness
    Elevate your Panama City escape with a Jack Nicklaus golf course, rejuvenating spa treatments, and poolside luxury at this 5-star retreat.
The price is Rp4.177.757
Rp4.595.533 total
includes taxes & fees
7 Aug - 8 Aug
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

9. Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Bella Vista
9.6 out of 10, Exceptional, (399 reviews)
  • cleanliness
    Indulgence awaits in this 4.5-star Panama City sanctuary featuring a full-service spa, outdoor pool, and elegant dining near Via Espana.
The price is Rp4.182.264
Rp4.600.490 total
includes taxes & fees
4 Sept - 5 Sept
Hyatt Regency Panama City

10. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (5,777 reviews)
  • cleanliness
    Exclusive Panama City escape offers lavish poolside retreats and gourmet dining experiences.
The price is Rp2.505.851
Rp2.756.436 total
includes taxes & fees
1 Sept - 2 Sept
Hotel Riu Plaza Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Panama City Hotel Reviews

Frequently asked questions

Are you searching for the perfect hotel for your luxury trip to Panama City?
Arrange a flight into Panama City (PAC-Marcos A. Gelabert Intl.) Airport or Balboa (BLB-Panama Pacifico Intl.) Airport, and then treat yourself to a stay at one of 24 luxurious hotels. Known for its casinos and shopping, Panama City also has some interesting things to see and do including Albrook Shopping Mall, so you may want to take in the local sights during your visit.
What's the best high-end hotel in Panama City?
Hotel Riu Plaza Panama is a luxury hotel with 3 restaurants and valet parking, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Megapolis Hotel Panamá and JW Marriott Panama are other upscale choices for your trip.
How many luxury hotels should I expect to find in Panama City?
Lie in the lap of luxury during your getaway to Panama City in one of Expedia's 24 luxury hotels.
When can I expect good weather in Panama City?
Planning for the weather is a good way to make your trip to Panama City relaxing and enjoyable, especially when you're splurging. The hottest months are usually March and April, with an average temperature of 27°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Panama City are July, August, June and November, with each month seeing an average of 369 mm of rainfall.
What's there to see and do in Panama City?
Experience Panama City and visit Albrook Shopping Mall, Via Espana and Iglesia del Carmen. If you have spare time during your trip, you might want to make a stop at Uruguay Street and Avenida Balboa.
How can I get around Panama City?
It's easier to get around town in style when you know your options. Walk to nearby metro stations such as Iglesia del Carmen Station, Vía Argentina and Santo Tomas Station. If you want to explore the larger area, hop on a train at Panama City Passenger Station.