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6 Nov - 8 Nov
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Our top choices for Downtown Clayton hotels

The Clayton Plaza Hotel sign with a stone wall and plants in front.

1. Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
Downtown Clayton
8.8 out of 10, Excellent, (3,513 reviews)
"Great location, nice rooms!"
United States
Martha
The price is Rp1.906.380
Rp2.225.744 total
includes taxes & fees
8 Nov - 9 Nov
Clayton Plaza Hotel & Extended Stay
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a modern building with large windows.

2. Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Downtown Clayton
8.8 out of 10, Excellent, (801 reviews)
"Beautiful hotel in a convenient location."
United States
Marsha
The price is Rp2.763.044
Rp3.253.151 total
includes taxes & fees
15 Nov - 16 Nov
Le Méridien St. Louis Clayton
A rooftop terrace with modern outdoor seating, a fire pit, and a view of the cityscape.

3. AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton
2.0 star property
Downtown Clayton
9.2 out of 10, Wonderful, (423 reviews)
"Great stay"
United States
anthony
The price is Rp2.331.608
Rp2.721.872 total
includes taxes & fees
8 Nov - 9 Nov
AC Hotel St. Louis Clayton
A lobby with a bar area, seating, and a patterned carpet.

4. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Downtown Clayton
9.2 out of 10, Wonderful, (587 reviews)
"Incredible stay! Loved the room, the staff were great, and the amenities were amazing! Definitely recommend staying here!"
United States
Kennedy
The price is Rp10.333.040
Rp12.062.780 total
includes taxes & fees
27 Nov - 28 Nov
The Ritz-Carlton, St. Louis
A traditional Tudor-style building with a black awning labeled "28 Sally's Inn."

5. Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Seven Gables, St. Louis West, a Tribute Portfolio Hotel
3.5 star property
Downtown Clayton
8.4 out of 10, Very good, (603 reviews)
"I always stay at the Seven Gables Inn while visiting St. Louis - fantastic, walkable neighborhood, for central STL, including vintage shopping & dining options. The boutique hotel is very ‘Old St. Louis’ with extremely modern, comfortable, quiet and safe rooms."
United States
Jennifer
The price is Rp3.341.440
Rp4.079.130 total
includes taxes & fees
4 Dec - 5 Dec
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
A digital display with three screens showing hotel information.

6. SpringHill Suites St. Louis Brentwood

SpringHill Suites St. Louis Brentwood
3.0 star property
2.9 km from Downtown Clayton
9.0 out of 10, Wonderful, (1,000 reviews)
"Staff was very friendly and rooms were clean."
United States
Aaron
The price is Rp2.271.816
Rp2.680.470 total
includes taxes & fees
22 Nov - 23 Nov
SpringHill Suites St. Louis Brentwood
An outdoor patio with a fire pit, seating, and a building in the background.

7. Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
2.2 km from Downtown Clayton
9.4 out of 10, Exceptional, (912 reviews)
"Beautiful accommodations! Helpful staff😊"
United States
Anna
The price is Rp2.145.131
Rp2.616.414 total
includes taxes & fees
29 Nov - 30 Nov
Courtyard by Marriott St. Louis Brentwood
An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

8. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
2.5 km from Downtown Clayton
9.6 out of 10, Exceptional, (1,004 reviews)
"Really enjoyed the breakfast and happy hours!"
United States
Stacey Rochelle
The price is Rp2.323.786
Rp2.759.944 total
includes taxes & fees
22 Nov - 23 Nov
Drury Plaza Hotel St. Louis Brentwood
The exterior of the Charles F. Knight Center with a stone facade, large arched entrance, and a sign above the doors.

9. The Knight Center at Washington University

The Knight Center at Washington University
2.5 star property
2.2 km from Downtown Clayton
9.4 out of 10, Exceptional, (717 reviews)
"We will absolutely stay here again when traveling to Wash U. Great hotel!"
United States
jeffrey
The price is Rp2.208.496
Rp2.539.506 total
includes taxes & fees
28 Nov - 29 Nov
The Knight Center at Washington University
A modern lounge area with a stone fireplace, comfortable seating, and a bar in the background.

10. Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
3.0 star property
0.7 km from Downtown Clayton
8.8 out of 10, Excellent, (1,000 reviews)
"Great location - staff was awesome!"
United States
Kevin
The price is Rp2.145.131
Rp2.525.634 total
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
A hotel room with a television on a wooden stand, a desk with a chair, a blue armchair, and a floor lamp.

11. Moonrise Hotel

Moonrise Hotel
4.0 star property
3.4 km from Downtown Clayton
9.0 out of 10, Wonderful, (2,049 reviews)
"Cool hotel!"
United States
Rebecca
The price is Rp2.701.726
Rp3.213.136 total
includes taxes & fees
18 Nov - 19 Nov
Moonrise Hotel
A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

12. Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
3.0 star property
10.4 km from Downtown Clayton
9.2 out of 10, Wonderful, (1,724 reviews)
"Near the airport; good breakfast."
United States
Cindy
The price is Rp1.757.888
Rp2.087.282 total
includes taxes & fees
19 Nov - 20 Nov
Wingate by Wyndham St. Louis Airport
A grand building with a fountain in front.

13. The Cheshire

The Cheshire
4.0 star property
3.1 km from Downtown Clayton
8.8 out of 10, Excellent, (1,000 reviews)
"Fantastic hotel, clean and nice rooms, great breakfast and location"
United States
Matthew
The price is Rp2.706.566
Rp3.213.721 total
includes taxes & fees
29 Nov - 30 Nov
The Cheshire
A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

14. Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
9.7 km from Downtown Clayton
9.2 out of 10, Wonderful, (1,014 reviews)
"Loved my stay"
United States
Thadora
The price is Rp1.990.805
Rp2.468.320 total
includes taxes & fees
11 Nov - 12 Nov
Hyatt Select St. Louis Airport
A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

15. Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
10.4 km from Downtown Clayton
9.4 out of 10, Exceptional, (3,346 reviews)
"Great stay for airport access"
United States
Rebecca
The price is Rp1.633.858
Rp1.940.011 total
includes taxes & fees
8 Nov - 9 Nov
Pear Tree Inn St. Louis Airport
A modern lobby with a grey sofa, two armchairs, a round table, and a chandelier. There are two posters on the wall and a reception desk in the background.

16. Holiday Inn St Louis SW - Route 66 by IHG

Holiday Inn St Louis SW - Route 66 by IHG
3.0 star property
12 km from Downtown Clayton
9.2 out of 10, Wonderful, (600 reviews)
"The Rte 66 theme was fun and yet classy. The attached restaurant was really delicious. Eating on the patio was really nice and happy hour prices made it all extra special"
United States
Susan
The price is Rp2.142.880
Rp2.548.588 total
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn St Louis SW - Route 66 by IHG
A spacious hotel lobby with multiple seating areas, a reception desk, and large windows offering a view of the cityscape.

17. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
9.3 km from Downtown Clayton
8.4 out of 10, Very good, (1,196 reviews)
"Great Hotel."
United States
Joy
The price is Rp2.019.392
Rp2.362.446 total
includes taxes & fees
20 Nov - 21 Nov
Renaissance St. Louis Airport Hotel
A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

18. Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport
3.0 star property
10.1 km from Downtown Clayton
9.2 out of 10, Wonderful, (1,457 reviews)
"Excellent place to stay, highly recommend."
United States
Ethan
The price is Rp2.087.758
Rp2.470.610 total
includes taxes & fees
22 Nov - 23 Nov
Drury Inn & Suites St. Louis Airport
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

19. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End, 6.3 km from Downtown Clayton
9.2 out of 10, Wonderful, (1,006 reviews)
"The hotel is beautiful, and we really enjoyed the restaurants--The Tenderloin Room was especially delicious!"
United States
Sara
The price is Rp2.705.244
Rp3.725.507 total
includes taxes & fees
22 Nov - 23 Nov
The Royal Sonesta Chase Park Plaza St. Louis
An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

20. Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
3.5 star property
Dogtown, 5.3 km from Downtown Clayton
9.4 out of 10, Exceptional, (1,000 reviews)
"Well maintained, great staff and very clean."
United States
Greg
The price is Rp2.367.701
Rp2.792.205 total
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn & Suites St. Louis at Forest Park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Downtown Clayton

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A rooftop terrace with modern outdoor seating, a fire pit, and a view of the cityscape.
AC Hotel St. Louis Clayton
2.0 star property
9.2
Wonderful
423 reviews
View
A lobby with a bar area, seating, and a patterned carpet.
The Ritz-Carlton, St. Louis
5.0 star property
9.2
Wonderful
587 reviews
View
The Clayton Plaza Hotel sign with a stone wall and plants in front.
Clayton Plaza Hotel & Extended Stay
3.5 star property
8.8
Excellent
3,513 reviews
View
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a modern building with large windows.
Le Méridien St. Louis Clayton
4.0 star property
8.8
Excellent
801 reviews
View
A traditional Tudor-style building with a black awning labeled "28 Sally's Inn."
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
3.5 star property
8.4
Very good
603 reviews
View

Hotels recommended for families in Downtown Clayton

The Clayton Plaza Hotel sign with a stone wall and plants in front.

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
Clayton
8.8 out of 10, Excellent, (3,513)
The price is Rp1.906.380
Rp2.225.744 total
includes taxes & fees
8 Nov - 9 Nov
Clayton Plaza Hotel & Extended Stay

Where to stay in Downtown Clayton

Find the best Downtown Clayton areas for the activities you enjoy most.
The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Old Courthouse to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

A historic building with a green dome and adjacent modern high-rise buildings.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Top Downtown Clayton Hotel Reviews

Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown

10/10 Excellent
"Ease of parking"
Melissa 1-night trip
Posted 2 hours ago
Tru By Hilton St. Louis Downtown

Frequently asked questions

What's it like in Downtown Clayton?
Travellers to the Downtown Clayton neighbourhood in St. Louis will be sure to enjoy their stay.
What's a favourite hotel to stay in Downtown Clayton?
Based on our traveller data, Clayton Plaza Hotel & Extended Stay is one of the top choices for your stay in Downtown Clayton. This hotel offers free breakfast and an indoor pool. Other good options for your stay in the area include AC Hotel St. Louis Clayton and Le Méridien St. Louis Clayton.
How many hotels can I expect to find in the Downtown Clayton area?
Expedia has 5 Downtown Clayton hotels and other accommodation options, and one might make a good home base for venturing out into the greater St. Louis area.
If I need to cancel my hotel reservation in Downtown Clayton, will I receive a refund?
Yes! Most hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the top deals on offer in Downtown Clayton.
What can I see and do in this St. Louis neighbourhood?
St. Louis Zoo, Shaw Park Tennis Center and Saint Louis Galleria Mall are just a few of the places to visit in and around Downtown Clayton. While you're out sightseeing, Tao Tennis Center and Center of Creative Arts are a couple of additional sights to visit in St. Louis.
How can I get around Downtown Clayton and the greater St. Louis area?
Ready to get out and explore the city? Clayton Station is the closest metro station.