Serra Mesa Travel Guide
San Diego
Visit Serra Mesa
Popular places to visit
San Diego Zoo
See nature up-close and personal at one of the country’s largest and most educational zoos.
San Diego Convention Center
During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's entertainment choices and fascinating museums.
SeaWorld
Animal interaction, entertaining rides and informative exhibits are all on offer at this family favorite destination.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
Mission Beach
A favorite vacation spot for 100 years, this seaside village combines old-fashioned charm with modern amenities.
Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
Things to do
USS Midway Museum with Direct-to-Gate
City Cruises San Diego: Premier Bottomless Mimosa Brunch Cruise
LEGOLAND® California Resort
San Diego: Museum of Illusions Entry Ticket
City Cruises San Diego: Signature Dinner Cruise
San Diego Whale Watching & Dolphin Cruise
Top hotels in Serra Mesa
Paradise Point Resort & Spa
Clean
Reviewed on 16 Feb 2026
Hard Rock Hotel San Diego
Great
Reviewed on 17 Feb 2026
The DEXTRO Little Italy, BW Premier Collection
Cool
Reviewed on 17 Feb 2026
The Sofia Hotel
Amazing overall. Parking was tricky though.
Reviewed on 17 Feb 2026
Wyndham San Diego Bayside
I was early for check in and my room wasn’t quite ready. We completed the check in process and I went off to lunch expecting the room to be ready in half an hour. It was ready when I went to the room. The counter person saved me from a later check in when the desk was busy! Thanks for making it work! ...
Reviewed on 17 Feb 2026
Days Inn by Wyndham San Diego Hotel Circle
We liked that it had a pool and jacuzzi
Reviewed on 17 Feb 2026
Other neighbourhoods around Serra Mesa
Mission Valley
Known for its stunning beaches and popular shops, there's plenty to explore in Mission Valley. Check out top attractions like Mission Valley Mall and Fashion Valley Mall, and jump on the metro at Hazard Center Station or Mission Valley Center Station to see more of the city.
North Park
North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.
Del Cerro
While there might not be top attractions in Del Cerro, you can explore the larger area and discover places like Cal Coast Credit Union Open Air Theater and Viejas Arena.
Old Town San Diego
The abundant dining options and seaside views are top of the list for many visitors to Old Town San Diego. A stop by Old Town San Diego State Park or Whaley House Museum might round out your trip.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
