Serra Mesa Holidays

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Where to stay in Serra Mesa

Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Serra Mesa
US Grant Hotel

Downtown San Diego

3 out of top 10 points of interest in this area
4.5/5(138 area reviews)

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Find hotels in Downtown San Diego

Top hotels in Serra Mesa

Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
The price is Rp2.159.200 per night from 24 Feb to 25 Feb
Rp2.159.200
Rp2.481.822 total
24 Feb - 25 Feb
includes taxes & fees
9/10 Wonderful! (3,364 reviews)
I love the Bayclub Hotel and Marina. The staff is helpful and friendly. The views are amazing. The restaurant is very good and they have happy hour from 2:00-6:00 each day. I absolutely enjoy the server Miriam, who works at breakfast time. She is always so friendly, so polite, and we will go out ...

Reviewed on 3 Feb 2026

Bay Club Hotel & Marina
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
The price is Rp14.948.307 per night from 19 Feb to 20 Feb
Rp14.948.307
Rp18.118.280 total
19 Feb - 20 Feb
includes taxes & fees
8.8/10 Excellent! (3,286 reviews)
Very clean hotel. I was always seeing someone cleaning.

Reviewed on 2 Feb 2026

Hard Rock Hotel San Diego
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
The price is Rp2.407.499 per night from 22 Feb to 23 Feb
Rp2.407.499
Rp3.655.138 total
22 Feb - 23 Feb
includes taxes & fees
8.6/10 Excellent! (2,385 reviews)
Always a good time

Reviewed on 30 Jan 2026

Paradise Point Resort & Spa
See all 9,074 properties in Serra Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Serra Mesa holiday package cost?
Be ready to book, because a trip to Serra Mesa starts from just . When you bundle your hotels, flights and car rentals into a package, you'll land the lowest prices.
How do I get a cheap travel package to Serra Mesa?
One of the simplest ways to save dollars (and time) is to bundle your bookings with Expedia. Flights, hotels, activities and rental cars — we've got everything you need. Pick the combination that best suits you and watch your savings pile up. Of course, a travel package is never one-size-fits-all. That's why we offer more than 550 partner airlines and 1,000,000 hotel options worldwide, which lets you customize your Serra Mesa holiday.
Where should I stay in Serra Mesa?
Most visitors to Serra Mesa put both San Diego Zoo and Balboa Park on their itineraries. Why not go for a hotel that's close to these fantastic attractions?
What are the top hotels in Serra Mesa?
Get your escape off to an excellent start by locking in a room at Central Location - 3br/2ba. Stay Weekly. Clean. It's one of most sought-after properties in Serra Mesa. Another comfortable option is Newly Remodeled Beautiful Beach Bound And Centrally Located San Diego Home.
How far in advance should I book my Serra Mesa holiday?
It's difficult to pick the best time for airfares, but we normally say the earlier, the better. Most international flights on Expedia become available up to 12 months in advance. If you're booking late, fear not. Budget prices appear from time to time just weeks before departure dates.
What does an Expedia Serra Mesa travel package include?
From flights and hotels to rental cars, Expedia can help you craft a Serra Mesa package that's perfect for you. Holidaying for a few weeks? Consider a flight, hotel and rental car bundle. If your break is short, a flight and hotel deal could be what you're after. Experiences can also be added once you've made your booking. Our travel packages make it a cinch to plan and save.
What should I know before booking a Serra Mesa travel package?
You can save a tidy sum by combining your hotels, airfares and rental cars. Once you've made your booking, you can add on things like day tours or experiences. Your next unforgettable holiday is only a few clicks away.
Can I choose my airline with a Serra Mesa Expedia holiday package?
With a holiday package, you're the one in charge. Whether you'd like to fly to Serra Mesa in economy or first class, simply choose from the available airline options. Expedia has access to over 550 partner airlines all over the world.
If I'm not able to travel, can I cancel my Serra Mesa holiday package?
Plans can change in the blink of an eye, so yes. You may be able to cancel or alter your Serra Mesa holiday package at no cost if you've booked in the last 24 hours. For bookings made more than 24 hours ago, you can still make the necessary changes, but your car rental company, hotel or airline may impose a charge. Want more information? Check out our Customer Service Portal. We'll help make sure your getaway goes off without a hitch.

Popular places to visit

San Diego Zoo featuring zoo animals, landscape views and a pond

San Diego Zoo

See nature up-close and personal at one of the country’s largest and most educational zoos.

San Diego Zoo
USS Midway Museum which includes military items

USS Midway Museum

Experience the thrills and hardships of Navy life at this waterfront museum which has become a San Diego landmark.

USS Midway Museum

Stadium Golf Center & Batting Cages

Enjoy a round of golf in San Diego at Stadium Golf Center & Batting Cages. Attend a sporting event or discover the beautiful sunsets in this walkable area.

Stadium Golf Center & Batting Cages

Things to do

USS Midway Museum with Skip-the-Line Entry

USS Midway Museum with Direct-to-Gate

Rp620.658
per adult
98% of travellers recommend
USS Midway Museum with Direct-to-Gate
San Diego Premier Bottomless Mimosa Brunch Cruise

City Cruises San Diego: Premier Bottomless Mimosa Brunch Cruise

Rp1.540.039
per adult
90% of travellers recommend
City Cruises San Diego: Premier Bottomless Mimosa Brunch Cruise
San Diego: Museum of Illusions Entry Ticket

San Diego: Museum of Illusions Entry Ticket

Rp588.700
per adult
80% of travellers recommend
San Diego: Museum of Illusions Entry Ticket
See all activities in San Diego
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.