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Our top choices for San Francisco hotels

1. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,329 reviews)
"Great location, helpful staff, efficient check-in and check-out, good breakfast, clean property, free parking"
United States
Bettyanne
The price is Rp1.860.914
Rp2.047.006 total
includes taxes & fees
28 Aug - 29 Aug
Ramada Plaza by Wyndham Panama Punta Pacifica

2. Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,000 reviews)
"Super staff Overall excellent hotel"
United States
Luis
The price is Rp3.110.387
Rp3.421.425 total
includes taxes & fees
7 Sept - 8 Sept
Sheraton Grand Panama

3. Aloft by Marriott Panama

Aloft by Marriott Panama
3.5 star property
San Francisco
8.8 out of 10, Excellent, (1,018 reviews)
"Nice hotel, rooms are comfortable and clean. Breakfast is ok with some alternatives"
United States
Mauricio
The price is Rp2.214.739
Rp2.436.213 total
includes taxes & fees
6 Sept - 7 Sept
Aloft by Marriott Panama

4. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,244 reviews)
"Excellent Room with a view - very diverse breakfast - nice location, really close to everything including the waterfront walk. Safe - thank you for a great stay."
Canada
Edward
The price is Rp2.033.520
Rp2.236.872 total
includes taxes & fees
3 Sept - 4 Sept
Plaza Paitilla Inn Hotel

5. Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,718 reviews)
"Clean room, Excellent breakfast options and tasty"
United States
Diana
The price is Rp1.992.257
Rp2.191.483 total
includes taxes & fees
27 Sept - 28 Sept
Decapolis Hotel Panama City

6. Modern Apartments at the Hub City views

Modern Apartments at the Hub City views
3.0 star property
San Francisco
10.0 out of 10, Exceptional, (1 review)
The price is Rp2.088.106
Rp2.296.917 total
includes taxes & fees
9 Sept - 10 Sept
Modern Apartments at the Hub City views

7. Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,006 reviews)
"Buffet breakfast was switched up daily, room was spacious and clean, staff was very accommodating, great access to nearby mall and good location for shuttle pickup for excursions. Would definitely stay again and highly recommend."
United States
Shereen
The price is Rp2.093.972
Rp2.303.369 total
includes taxes & fees
13 Sept - 14 Sept
Courtyard by Marriott Panama Multiplaza Mall

8. Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
San Francisco
9.2 out of 10, Wonderful, (664 reviews)
"Everything was perfect, breakfast was good with many options and the fruits amazing, staff are very friendly and helpful, I really recommend this hotel."
United States
Frank David Delgado
The price is Rp3.650.938
Rp4.016.032 total
includes taxes & fees
25 Sept - 26 Sept
Residence Inn by Marriott Panama City

9. San Francisco by Wynwood House

San Francisco by Wynwood House
3.0 star property
San Francisco
9.2 out of 10, Wonderful, (61 reviews)
"I enjoyed my stay, during my one night layover in Panama City. The apartment was beautiful, cozy and charming - just like in the pictures. It was a little hard to find, because it’s in a residential building and not a hotel - but the staff was responsive and kind."
United States
Claire
The price is Rp1.944.470
Rp2.581.992 total
includes taxes & fees
1 Sept - 2 Sept
San Francisco by Wynwood House

10. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,105 reviews)
"Absolutely loved the view from my room and the staff was very forthcoming and helpful, the breakfast was lovely too, definitely a 10/10 stay."
United States
Mariah
The price is Rp3.046.406
Rp3.351.065 total
includes taxes & fees
30 Aug - 31 Aug
Las Americas Golden Tower Panama

11. Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
8.0 out of 10, Very good, (48 reviews)
"Excellent apartment and service."
United States
Dustin M
The price is Rp679.341
Rp2.686.171 total
includes taxes & fees
30 Aug - 31 Aug
Boutique Apartments Atlapa

12. Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.6 out of 10, Good, (223 reviews)
"Great location"
United States
Hugo
The price is Rp1.051.470
Rp3.641.382 total
includes taxes & fees
31 Aug - 1 Sept
Boutique Apartments Panamá Coco del Mar

13. Modern Apartments PH Living 73 SF

Modern Apartments PH Living 73 SF
3.5 star property
San Francisco
7.4 out of 10, Good, (3 reviews)
"To the owner, it would help if the top sheet is larger than the bed, difficult for two people to cover themselves"
United States
Dawid
The price is Rp1.421.207
Rp1.563.328 total
includes taxes & fees
5 Sept - 6 Sept
Modern Apartments PH Living 73 SF

14. Casa Orquídea

Casa Orquídea
2.0 star property
San Francisco
7.8 out of 10, Good, (14 reviews)
"Really great location, very kind and helpful staff. Some things may need some updating, but i would not think twice before booking the place!"
United States
Brett
The price is Rp1.403.662
Rp1.544.028 total
includes taxes & fees
9 Sept - 10 Sept
Casa Orquídea

15. Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very good, (1,695 reviews)
"The staff are welcoming, the property is extremely clean and well kept and the food was excellent."
United States
Martin
The price is Rp3.475.418
Rp3.822.960 total
includes taxes & fees
3 Sept - 4 Sept
Megapolis Hotel Panamá

16. Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
4.0 star property
San Francisco
8.4 out of 10, Very good, (27 reviews)
"Exactly like the photos was very nice"
Canada
Jessica
The price is Rp2.452.421
Rp2.697.663 total
includes taxes & fees
28 Aug - 29 Aug
Dovle Residences by HMS-Preferred Member

17. The Hub Modern Apartments by Wynwood

The Hub Modern Apartments by Wynwood
3.0 star property
San Francisco
The price is Rp2.552.112
Rp3.392.182 total
includes taxes & fees
29 Aug - 30 Aug
The Hub Modern Apartments by Wynwood

18. Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (3 reviews)
"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "
United States
Gary
The price is Rp1.467.630
Rp4.324.546 total
includes taxes & fees
6 Sept - 7 Sept
Wanders Panama by Boutique Apartments

19. JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,007 reviews)
"Hotel was clean and staff was very helpful."
United States
Benjamin A
The price is Rp4.664.694
Rp5.131.163 total
includes taxes & fees
20 Sept - 21 Sept
JW Marriott Panama

20. Stylish Apartment With Pool Gym in Panama

Stylish Apartment With Pool Gym in Panama
2.0 star property
San Francisco
8.0 out of 10, Very good, (1 review)
"Would stay here again"
United States
Stepp
The price is Rp2.391.134
Rp2.934.408 total
includes taxes & fees
27 Sept - 28 Sept
Stylish Apartment With Pool Gym in Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in San Francisco

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A balcony with wicker chairs and a view of the cityscape.
Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
9.6
Exceptional
1,329 reviews
View
A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.
Aloft by Marriott Panama
3.5 star property
8.8
Excellent
1,018 reviews
View
A covered outdoor seating area with a view of a city skyline and water.
Plaza Paitilla Inn Hotel
3.5 star property
9.4
Exceptional
2,244 reviews
View
A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.
Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
9.0
Wonderful
1,006 reviews
View
A buffet with various food items and a decorative plant.
Sheraton Grand Panama
4.0 star property
8.6
Excellent
1,000 reviews
View

Where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most. Learn more about San Francisco
Learn more about San Francisco

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Lotería Station or Santo Tomás Station to explore sights like Via Espana.

Top San Francisco Hotel Reviews

Find out more about San Francisco

Top reasons to visit San Francisco

  • Vibrant City Life: San Francisco is known for its lively atmosphere, offering a mix of trendy bars, delightful eateries, and cool hangouts.
  • Stunning Waterfront Promenade: Avenida Balboa provides a picturesque setting for leisurely strolls along the waterfront.
  • Diverse Accommodation Options: From luxury hotels to budget-friendly hostels, there's something for every type of traveller.
  • Rich Cultural Experiences: Immerse yourself in the local culture through historical neighbourhoods and friendly locals.
  • Family-Friendly Activities: The city offers a range of attractions suitable for visitors of all ages.

Find great hotels near San Francisco

Discover a variety of accommodation options in San Francisco, catering to every type of traveller. Whether you prefer a comfortable hotel, a vibrant hostel, or a family-friendly apartment, you'll find it all here. Enjoy essential amenities such as air conditioning and explore unique lodging like beach houses or the charming casa escondida, ensuring an unforgettable experience during your stay in this lively city.

  • Las Americas Golden Tower Panama: Experience a blend of business sophistication and relaxation at the 4-star Las Americas Golden Tower Panama. Located conveniently in the city centre, this hotel caters to those seeking a spa-themed getaway with its full-service spa and relaxing pool amenities. Guests can unwind in the sauna or enjoy the accessible pool, making it an ideal choice for travellers looking for a rejuvenating stay amidst the vibrant atmosphere of the city.
  • Megapolis Hotel Panamá: With a luxurious 4.5-star experience, Megapolis Hotel Panamá is perfect for families and business travellers alike. Situated just 1.6km from San Francisco, this hotel offers a wide array of child-friendly amenities, including an arcade game room, playground, and on-site babysitting services to ensure a fun-filled stay for younger guests. Its upscale facilities and attentive service create an inviting environment for families seeking a memorable vacation.
  • Hampton by Hilton Panama: The 3-star Hampton by Hilton Panama provides an excellent base for business travellers and city explorers. Located in the heart of the city, this hotel offers comfort and convenience with essential amenities for a productive stay. Guests appreciate the welcoming atmosphere and the strategic location that allows easy access to local attractions, making it a reliable choice for those looking to balance work and leisure during their visit.

Where to stay near San Francisco

San Francisco offers a delightful blend of family-friendly activities and vibrant city life. Nestled in Panama City, the area is known for its appealing atmosphere, from luxury accommodations to budget-friendly options. Don’t miss Avenida Balboa, a stunning waterfront promenade perfect for leisurely strolls. Nearby neighbourhoods provide a rich historical backdrop, making it an attractive destination for both relaxation and exploration. Experience the warmth of friendly locals while indulging in the region’s diverse offerings.

  • Panama City: Nestled at the heart of Panama Province, Panama City is a dynamic urban centre that welcomes travellers year-round. Peak visitor times occur in January, July, and September, making it an ideal destination for family holidays, business trips, and city-themed adventures. This vibrant metropolis boasts a plethora of shopping centres and malls, perfect for indulging in retail therapy. Visitors can explore local landmarks such as beautiful beaches, lush parks, and lively streets, ensuring an enriching travel experience.
  • Obarrio: Located a mere 1.4km from San Francisco, Obarrio is a bustling neighbourhood that captures the essence of urban life in Panama City. It experiences a steady flow of visitors throughout the year, with heightened interest in February, April, and September. Families and business travellers alike will find plenty to do here, from exploring the numerous shopping areas to relaxing in nearby parks and tourist precincts. Obarrio's blend of modernity and local charm makes it a must-visit for any tourist.
  • Bella Vista: Just 1.6km away from San Francisco, Bella Vista is a lively neighbourhood that enchants visitors with its cultural vibrancy. This area sees a consistent influx of tourists, particularly in February, March, and December. Bella Vista is ideal for families and business travellers, offering a variety of shopping centres, malls, and areas. The neighbourhood is also home to pleasant streets, parks, and a tourist precinct, making it a delightful spot for leisurely exploration and immersion in local life.

Things to do in and around San Francisco

San Francisco is an ideal destination for family and business-themed vacations, offering a vibrant array of activities. Visitors can explore various shopping centres and areas, while also enjoying numerous entertainment options. The city boasts trendy bars, delightful eateries, and cool hangouts, making it a perfect place to unwind and experience the local culture.

Shopping

In San Francisco, you can explore Multiplaza Pacific Mall and Multicentro Panama, both offering a vibrant mix of shops and entertainment. For a broader selection, head to Pacific Center, located 1.6km away, where you'll find family-friendly options and unique gifts to take home.

Recreation

Experience the vibrant sports atmosphere at Estadio Nacional Rod Carew, Estadio Rommel Fernandez, and Maracana Stadium, all located a mere 6.4km from San Francisco. Engage in various recreational activities, from lively matches to fitness events, ensuring a rejuvenating blend of wellness and excitement.

Adventure

Embark on the Honeycreeper Ridge Trail, a scenic hike located 37.0km from San Francisco, where you can immerse yourself in nature and enjoy the stunning views. For an adrenaline rush, try Gatun Eco Adventures, a thrilling zipline ropes course situated 46.7km away, surrounded by lush landscapes.

Nightlife

Experience the vibrant nightlife in San Francisco with a visit to the National Theater and Anita Villalaz Theater, both offering a rich blend of romance, entertainment, and culture just 4.8km away. For a closer option, enjoy the Theatre Circle, only 1.6km away, immersing yourself in the city's artistic charm.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for San Francisco

To save money during your visit to San Francisco, consider travelling between September and November when prices are lower. Book your stay on a Tuesday for the best rates, and avoid Saturdays which are the priciest. Use Expedia’s search tool to filter for your budget and preferences, and opt for Eco-certified hotels for sustainable options. Combine your hotel with flights and activities for additional savings. Keep an eye out for deal alerts to ensure you snag the best offers.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around San Francisco are September to November, where the prices are slightly lower. This is in comparison to January and March to April, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around San Francisco is Tuesday. The most expensive day to stay around San Francisco is Saturday.
  • Find cheap hotels on Expedia: Utilise Expedia’s search tool to refine your preferences, such as your budget, preferred location, and the type of hotel you desire. For instance, selecting the Eco-certified filter will showcase sustainable and environmentally friendly hotels currently available. To find the most affordable prices and offers, simply sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel reservation in San Francisco with your flights and activities through an Expedia package.

Find the best attractions near San Francisco

San Francisco is an ideal destination for family, city-themed, and business vacations, offering a diverse array of attractions such as vibrant streets, urban parks, and event venues. Visitors can immerse themselves in the city's rich culture and enjoy outdoor experiences, making it a perfect locale for those seeking both urban exploration and leisure activities. With its unique charm, San Francisco promises to leave a lasting impression on every traveller.

  • Cinta Costera: A vibrant urban park, Cinta Costera offers a scenic promenade perfect for leisurely strolls and family outings. Enjoy stunning views of the bay and the city skyline, making it a fantastic spot for picnics and outdoor activities.
  • Avenida Balboa: This iconic street is a bustling artery of the city, lined with modern skyscrapers and lush greenery. Ideal for a relaxing walk or a bike ride, Avenida Balboa features a lively atmosphere and picturesque views of the waterfront.
  • Panama Viejo: A UNESCO World Heritage site, Panama Viejo is steeped in history and culture. Explore the remnants of the old city, including ancient ruins and historical landmarks, providing a fascinating glimpse into Panama's colonial past.

Best time to go to San Francisco

The best time to visit San Francisco is dependent on what kind of holiday you are seeking. April is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. November is its coolest month on average. At this time, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.8°F (26.0°C)No RainMostly SunnyAverageSlightly High
February79.2°F (26.2°C)No RainMostly SunnySlightly HighAverage
March79.7°F (26.5°C)No RainMostly SunnyAverageSlightly High
April80.4°F (26.9°C)Light RainMostly SunnyAverageSlightly High
May80.2°F (26.8°C)Frequent RainMostly CloudySlightly LowAverage
June79.9°F (26.6°C)Frequent RainMostly CloudyAverageAverage
July79.3°F (26.3°C)Frequent RainMostly CloudySlightly HighAverage
August79.2°F (26.2°C)Frequent RainMostly CloudyAverageAverage
September79.3°F (26.3°C)Frequent RainMostly CloudySlightly HighSlightly Low
October78.6°F (25.9°C)Frequent RainMostly CloudySlightly LowSlightly Low
November78.3°F (25.7°C)Frequent RainMostly CloudyAverageSlightly Low
December78.6°F (25.9°C)Light RainMostly CloudySlightly LowAverage

The nearest major airports for your trip to San Francisco

When travelling to San Francisco, you can fly into two major airports: Panama City (PAC-Marcos A. Gelabert International), located 6.4km away, with nearby hotels such as the luxurious W Panama and Hilton Panama, both offering various airport transportation services. Alternatively, Balboa (BLB-Panama Pacifico International) is situated 12.9km away, with excellent hotel options like Sortis Hotel, Spa & Casino and Megapolis Hotel Panamá, which also provide comprehensive shuttle services. For those seeking a more secluded experience, Contadora Island (OTD) lies 66.0km from San Francisco, with charming accommodations like Mar Y Oro and B&B Gerald's, both ensuring easy access to the airport.

Frequently asked questions

What is San Francisco like?
San Francisco is a welcoming neighbourhood that travellers like for its restaurants. Make sure that you visit Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.
Where is the best hotel for a stay in San Francisco?
Based on our traveller data, Megapolis Hotel Panamá is one of the top choices for your stay in San Francisco. This hotel is steps from Avenida Balboa, and offers a full-service spa and a casino. Other good choices for your stay in the area include Aloft by Marriott Panama and Courtyard by Marriott Panama Multiplaza Mall.
How many hotels can I expect to find in San Francisco?
If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 329 San Francisco hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in San Francisco, will I receive a refund?
Yes! Most hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in San Francisco.
What is there to do in this Panama City neighbourhood?
While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa or Multicentro Panama might be the perfect way to find that souvenir you've been looking for. Calle 50 and Via Espana are some other stops worth a visit in the neighbourhood. A few places to visit in the area around San Francisco include Panama Canal Murals, Colonial Religious Art Museum and Bingo 90. When you're sightseeing in Panama City, Pacific Center and Soho City Center are also worth a stop.