Photo by Fabiola Tile

Search Hotels in San Francisco, Panama City

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Top Trending Hotels Near San Francisco, Panama City

Courtyard by Marriott Panama Multiplaza Mall

4.0 star property
8.8 out of 10, Excellent, (1001)
"The breakfast buffet was excellent and the staff was friendly "
The price is Rp2.076.410
Rp2.284.051 total
includes taxes & fees
1 Nov - 2 Nov
Courtyard by Marriott Panama Multiplaza Mall

Aloft Panama

3.5 star property
8.6 out of 10, Excellent, (859)
"We stayed here for a week and it was filled with happy staff who were very courteous ! They made sure we were taken care of at all times and I will stay here again when we return. "
The price is Rp1.937.871
Rp2.131.659 total
includes taxes & fees
2 Nov - 3 Nov
Aloft Panama

Ramada Plaza by Wyndham Panama Punta Pacifica

4.0 star property
9.6 out of 10, Exceptional, (1059)
"Family-friendly hotel, tasty breakfast options daily and overall friendly staff and clean space."
The price is Rp1.802.054
Rp1.982.259 total
includes taxes & fees
2 Nov - 3 Nov
Ramada Plaza by Wyndham Panama Punta Pacifica

Sheraton Grand Panama

4.0 star property
8.6 out of 10, Excellent, (961)
"Relaxing but close by to everything "
The price is Rp2.221.098
Rp2.443.208 total
includes taxes & fees
1 Nov - 2 Nov
Sheraton Grand Panama

Boutique Apartments Panamá Coco del Mar

3.5 star property
7.6 out of 10, Good, (135)
"Beautiful view! "
The price is Rp636.666
Rp2.946.042 total
includes taxes & fees
5 Oct - 6 Oct
Boutique Apartments Panamá Coco del Mar

Megapolis Hotel Panamá

4.5 star property
8.4 out of 10, Very good, (1108)
"Great place "
The price is Rp2.136.934
Rp2.350.627 total
includes taxes & fees
26 Oct - 27 Oct
Megapolis Hotel Panamá

Plaza Paitilla Inn Hotel

3.5 star property
9.4 out of 10, Exceptional, (2112)
"Stayed 4 nights excellent property and views from the room"
The price is Rp2.501.118
Rp2.751.230 total
includes taxes & fees
12 Oct - 13 Oct
Plaza Paitilla Inn Hotel

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1002)
"The staff is top notch, the accommodations amazing, the dining options great, close to airport and activities "
The price is Rp3.654.050
Rp4.019.455 total
includes taxes & fees
17 Oct - 18 Oct
JW Marriott Panama

Decapolis Hotel Panama City

4.0 star property
8.6 out of 10, Excellent, (1345)
"Good price , location and tasty breakfast "
The price is Rp1.407.832
Rp1.548.615 total
includes taxes & fees
24 Oct - 25 Oct
Decapolis Hotel Panama City

San Francisco by Wynwood House

3.0 star property
9.2 out of 10, Wonderful, (50)
"Good comfy rooms"
The price is Rp1.562.467
Rp2.175.159 total
includes taxes & fees
7 Oct - 8 Oct
San Francisco by Wynwood House

Las Americas Golden Tower Panama

4.0 star property
9.0 out of 10, Wonderful, (1000)
"We ejoyed our stay here, very nice pool and gym area."
The price is Rp2.392.194
Rp2.631.364 total
includes taxes & fees
2 Nov - 3 Nov
Las Americas Golden Tower Panama

Residence Inn by Marriott Panama City

4.0 star property
9.0 out of 10, Wonderful, (516)
"Stayed here while a relative was hospitalized, easy access to the hospital and shopping center with lots of food options. If visiting Panama city it is very conveniently located."
The price is Rp2.379.275
Rp2.617.203 total
includes taxes & fees
2 Nov - 3 Nov
Residence Inn by Marriott Panama City

Boutique Apartments Atlapa

3.0 star property
7.4 out of 10, Good, (21)
"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"
Boutique Apartments Atlapa

Casa Orquídea

2.0 star property
9.0 out of 10, Wonderful, (2)
"For me was very convenient "
The price is Rp1.269.738
Rp1.396.712 total
includes taxes & fees
17 Oct - 18 Oct
Casa Orquídea

Wanders Panama by Boutique Apartments

4.0 star property
10.0 out of 10, Exceptional, (1)
"I will go again thank you so much"
The price is Rp2.641.073
Rp4.712.702 total
includes taxes & fees
17 Oct - 18 Oct
Wanders Panama by Boutique Apartments

w Bright 1BR w Private Balcony in San Francisco

2.0 star property
w Bright 1BR w Private Balcony in San Francisco

w Premium 1BR w Balcony in San Francisco

2.0 star property
w Premium 1BR w Balcony in San Francisco

Crowne Plaza Panama Airport by IHG

4.0 star property
8.4 out of 10, Very good, (2229)
"near airport, staff super helpful "
The price is Rp2.020.686
Rp2.222.755 total
includes taxes & fees
2 Nov - 3 Nov
Crowne Plaza Panama Airport by IHG

Central Hotel Panama Casco Viejo

4.0 star property
9.0 out of 10, Wonderful, (1000)
"Very beautiful hotel with helpful staff. Very good dining options. "
Central Hotel Panama Casco Viejo

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (4339)
"Excellent stay!!"
The price is Rp1.965.371
Rp2.161.908 total
includes taxes & fees
5 Oct - 6 Oct
Hotel Riu Plaza Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most. Learn more about San Francisco
Learn more about San Francisco

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Cinta Costera.

Top San Francisco Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What is San Francisco like?

San Francisco is a welcoming neighbourhood that travellers like for its restaurants. Make sure that you visit Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.

Where is the best hotel for a stay in San Francisco?

Based on Expedia customer reviews, Ramada Plaza by Wyndham Panama Punta Pacifica is the highest ranked property in San Francisco. This hotel is a short 4-minute walk from Multiplaza Pacific Mall, and it offers free breakfast and a restaurant. Other top choices in the neighbourhood include Plaza Paitilla Inn Hotel and Residence Inn by Marriott Panama City.

How many hotels can I expect to find in San Francisco?

If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 216 San Francisco hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in San Francisco, will I receive a refund?

Yes! Most hotel reservations are fully refundable provided that you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in San Francisco.

What is there to do in this Panama City neighbourhood?

While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa or Pacific Center might be the perfect way to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops worth a visit in the neighbourhood. A few places to visit in the area around San Francisco include Colonial Religious Art Museum, Bingo 90 and Soho City Center. When you're sightseeing in Panama City, National Shrine of the Heart of Mary and Panama Viejo Museum are also worth a stop.