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Our top choices for Santa Ana hotels

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (62 reviews)
"We live this property and stay here whenever we are in town."
United States
chris
The price is Rp1.553.604
Rp1.708.964 total
includes taxes & fees
25 Jan - 26 Jan
Casco View Apartments

La Manzana by Wynwood House

La Manzana by Wynwood House
3.0 star property
Santa Ana
7.2 out of 10, Good, (15 reviews)
"Great hotel. Very close to Casco viejo"
United States
LUCILA
The price is Rp1.109.476
Rp1.684.817 total
includes taxes & fees
20 Jan - 21 Jan
La Manzana by Wynwood House

Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (58 reviews)
"Excelente "
Mexico
David
The price is Rp428.254
Rp471.147 total
includes taxes & fees
20 Jan - 21 Jan
Hostal La Cigarra

Hotel República

Hotel República
2.0 star property
Santa Ana
6.6 out of 10, (182 reviews)
"Fantastic customer service"
United States
OLGA
Hotel República

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Obarrio, 4.1 km from Santa Ana
8.8 out of 10, Excellent, (1,000 reviews)
"Great hotel"
United States
Hugh
The price is Rp2.279.745
Rp2.507.720 total
includes taxes & fees
20 Jan - 21 Jan
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
4.0 star property
Bella Vista, 3.3 km from Santa Ana
7.8 out of 10, Good, (1,004 reviews)
"Clean, nice location, bery friendly staff"
United States
Hadjera
The price is Rp1.588.222
Rp1.747.044 total
includes taxes & fees
21 Jan - 22 Jan
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 3.6 km from Santa Ana
9.0 out of 10, Wonderful, (4,851 reviews)
"Great place to stay"
United States
Maria Teresa
The price is Rp1.953.747
Rp2.149.122 total
includes taxes & fees
18 Feb - 19 Feb
Hotel Riu Plaza Panama

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este, 10.2 km from Santa Ana
9.4 out of 10, Exceptional, (195 reviews)
"Really loved this place"
United States
Alejandra
The price is Rp1.413.442
Rp2.334.965 total
includes taxes & fees
20 Jan - 21 Jan
Arcadia Condo Suites

ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport
2.5 star property
20.5 km from Santa Ana
9.0 out of 10, Wonderful, (53 reviews)
"Great staff and nice boutique hotel "
United States
Margie
The price is Rp2.026.440
Rp2.630.319 total
includes taxes & fees
20 Jan - 21 Jan
ORHO HOTEL BOUTIQUE PANAMA Airport

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
Punta Paitilla, 3.5 km from Santa Ana
8.4 out of 10, Very good, (1,375 reviews)
"Lovely breakfast and very clean and friendly staff!!!"
United States
Ravindra
Megapolis Hotel Panamá

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
Punta Paitilla, 3.6 km from Santa Ana
8.6 out of 10, Excellent, (1,509 reviews)
"Nice comfortable hotel and very friendly staff."
Canada
norah
The price is Rp2.417.256
Rp2.658.982 total
includes taxes & fees
13 Feb - 14 Feb
Decapolis Hotel Panama City

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
San Felipe, 0.9 km from Santa Ana
9.2 out of 10, Wonderful, (1,005 reviews)
"Great hotel!"
United States
Alejandro
The price is Rp17.982.291
Rp19.780.520 total
includes taxes & fees
14 Feb - 15 Feb
Central Hotel Panama Casco Viejo

Hilton Panama

Hilton Panama
5.0 star property
Bella Vista, 3 km from Santa Ana
8.8 out of 10, Excellent, (1,003 reviews)
"Amazing location in downtown Panama City. Staff is super "
Canada
Karianne
The price is Rp3.480.073
Rp3.828.114 total
includes taxes & fees
15 Feb - 16 Feb
Hilton Panama

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
El Cangrejo, 3.5 km from Santa Ana
9.0 out of 10, Wonderful, (660 reviews)
"Great staff, good location"
United States
Lazaro
The price is Rp1.238.324
Rp1.838.994 total
includes taxes & fees
20 Jan - 21 Jan
Waymore Hotel Spa & Casino

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
Punta Paitilla, 3.6 km from Santa Ana
9.0 out of 10, Wonderful, (1,004 reviews)
"Great staff, great room, great time in Panama"
United States
Darius
The price is Rp2.580.502
Rp2.838.552 total
includes taxes & fees
9 Feb - 10 Feb
Las Americas Golden Tower Panama

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 3.4 km from Santa Ana
9.4 out of 10, Exceptional, (2,153 reviews)
"Definitely a great place to stay. Staff was excellent. "
United States
Eric
The price is Rp1.822.952
Rp2.005.331 total
includes taxes & fees
24 Jan - 25 Jan
Plaza Paitilla Inn Hotel

MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel
3.5 star property
Amador, 4.8 km from Santa Ana
8.2 out of 10, Very good, (215 reviews)
"Great rooms, pleasant staff, lovely location, lots of eats and drinks options"
United States
Rajiv Sachin
The price is Rp1.170.269
Rp1.287.296 total
includes taxes & fees
20 Jan - 21 Jan
MARINN Tropical Vibes Hotel

Riande Urban Hotel

Riande Urban Hotel
3.5 star property
El Cangrejo, 3.8 km from Santa Ana
8.8 out of 10, Excellent, (1,056 reviews)
"good location most staff very friendly "
Canada
Ron
The price is Rp1.420.282
Rp1.562.310 total
includes taxes & fees
21 Jan - 22 Jan
Riande Urban Hotel

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
7.5 km from Santa Ana
8.0 out of 10, Very good, (1,002 reviews)
"Beautiful property and amazing staff"
United States
CARMEN
The price is Rp4.294.702
Rp4.724.172 total
includes taxes & fees
30 Jan - 31 Jan
The Westin Playa Bonita Panama

MARINN PLACE Financial District

MARINN PLACE Financial District
3.5 star property
Campo Alegre, 3.3 km from Santa Ana
9.2 out of 10, Wonderful, (302 reviews)
"Second stay, very nice"
Canada
Xiaozhi
MARINN PLACE Financial District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Crown Casino.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Felipe

While visiting San Felipe, you might make a stop by sights like Interoceanic Canal Museum and Museum of History Panama.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Top Santa Ana Hotel Reviews

Find out more about Santa Ana

Top reasons to visit Santa Ana

  • Vibrant Shopping Centres: Santa Ana boasts a range of shopping venues, perfect for family outings and leisurely exploration.
  • Scenic Avenida Balboa: Enjoy breathtaking views and impressive architecture along this iconic promenade.
  • Cultural Attractions: Discover historical museums and cathedrals that offer a glimpse into Panama's rich heritage.
  • Outdoor Activities: Engage in bike lanes, boat tours, and city walks for an adventurous experience.
  • Diverse Accommodation: Choose from various lodging options catering to both leisure and business travellers, ensuring a comfortable stay.

Find great hotels near Santa Ana

In Santa Ana, you’ll discover a delightful selection of accommodation options, ranging from hotels to apartments, perfect for every type of traveller. Whether you're seeking a city-themed retreat, a pet-friendly haven, or a comfortable base for business travel, Santa Ana has you covered. Many establishments offer essential amenities such as air conditioning and all-inclusive options, ensuring a pleasant stay in this charming area of Panama City.

  • Residencial & Hotel Palazzo: Experience the vibrant city life at Residencial & Hotel Palazzo, a comfortable 3-star hotel located just 1.4km from Santa Ana. Ideal for urban adventurers, this property offers a city-themed vacation experience with easy access to local attractions. Guests can enjoy well-appointed rooms and a welcoming atmosphere, making it a great base for exploring the bustling streets of Panama City.
  • Tantalo Hotel: Positioned a mere 644m from Santa Ana, the 3.5-star Tantalo Hotel is perfect for both business travellers and those seeking an exciting city escape. With a chic, contemporary design, this hotel features modern amenities and a vibrant social scene, including a rooftop bar that offers stunning views of the city skyline. Its prime location allows guests to immerse themselves in the local culture and nightlife, ensuring a memorable stay.
  • La Concordia Boutique Hotel: For a family-friendly and pet-friendly experience, look no further than La Concordia Boutique Hotel, located just 483m from Santa Ana. This 4-star establishment caters to families with children, offering amenities such as babysitting services and high chairs. The hotel is also welcoming to pets, with specific policies in place to ensure a comfortable stay for all guests. With its charming atmosphere and focus on family care, La Concordia is a delightful choice for those travelling with loved ones.

Where to stay near Santa Ana

Santa Ana, a vibrant neighbourhood in Panama City, offers an array of experiences for all types of travellers. Explore the stunning Avenida Balboa with its breathtaking views and impressive architectural elements. The friendly atmosphere and family-friendly options make it perfect for a leisurely visit. Nearby, you can discover beautiful places that reflect the charm of an Asian city, providing a unique blend of relaxation and luxury. Santa Ana truly captures the essence of Panamanian hospitality.

  • Panama City: As the vibrant capital of Panama, Panama City serves as a gateway to the rich culture and history of the country. Located in close proximity to Santa Ana, this bustling metropolis offers a mix of modern skyscrapers and historical sites. Visitors can indulge in shopping at various centres and enjoy the local beaches, parks, and lively streets. The city is particularly popular among families and business travellers, and with its year-round appeal, there’s always something to experience, whether it’s the vibrant nightlife or the serene parks.
  • Casco Viejo: A mere 644m from Santa Ana, Casco Viejo is a UNESCO World Heritage site renowned for its colonial charm and historical significance. This picturesque neighbourhood is filled with cobblestone streets, colourful buildings, and a variety of shops and restaurants. Popular for family outings and cultural explorations, visitors can enjoy relaxing at parks, shopping in the local area, or soaking up the sun at nearby beaches. The atmosphere here is energetic, particularly during peak seasons in January and March to April, making it a must-visit destination.
  • Barrio Chino: Just 322m from Santa Ana, Barrio Chino, or Chinatown, is a vibrant neighbourhood that celebrates Chinese culture within Panama. This area boasts a variety of shopping options, from bustling markets to modern shopping centres, as well as theatres showcasing local performances. Visitors can immerse themselves in the rich history at nearby museums and historic places of worship. With its peak visitor arrivals in February to March and December, Barrio Chino offers a unique blend of cultural experiences, making it an intriguing stop on your journey.

Things to do near Santa Ana

Santa Ana in Panama City is perfect for family, city, and business-themed vacations. Visitors can explore vibrant shopping centres and areas, while also enjoying activities such as bike lanes, boat tours, and city walks. Adventure seekers will find plenty to do, making it an ideal destination for those looking to experience the charm and excitement of Panama City.

Shopping

In Santa Ana, you can enjoy shopping at Albrook Shopping Mall, just 1.6km away, offering a vibrant mix of entertainment and family-friendly options. For a local experience, visit Avenida Central, 483m away, featuring a lively atmosphere perfect for souvenirs and gifts.

Recreation

Experience the vibrant atmosphere at Maracana Stadium, only 1.3km from Santa Ana, where you can enjoy exciting sports events. For a broader range of activities, Estadio Nacional Rod Carew and Estadio Rommel Fernandez, located 6 and 11.3km away respectively, also offer thrilling sports experiences.

Adventure

Embark on the Honeycreeper Ridge Trail, located 43.5km from Santa Ana, where you'll encounter breathtaking scenery and a true outdoor adventure. Experience the thrill of Gatun Eco Adventures, a zipline ropes course 48.3km away, offering exhilarating rides amidst lush surroundings and vibrant adventure vibes.

Nightlife

Experience the vibrant nightlife in Santa Ana by visiting the National Theatre, offering a blend of romance and culture just 966m away. For more theatrical charm, check out Anita Villalaz Theatre, located 1.3km away, or enjoy a show at Amador Theatre, a mere 483m from Santa Ana.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Ana

For a budget-friendly trip to Santa Ana, consider visiting between September and November when accommodation prices are lower. Tuesdays are the cheapest days to stay, while Saturdays tend to be more expensive. Utilise Expedia’s search tool to find the best deals based on your budget and preferences, and consider booking a package that combines flights and hotels for additional savings. Look for app deals and instant savings to further cut costs. Additionally, explore free activities in the area to make the most of your visit without overspending.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Santa Ana are September to November, where the prices are slightly lower. This is in comparison to January and March to April, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Santa Ana is Tuesday. The most expensive day to stay around Santa Ana is Saturday.
  • Find cheap hotels on Expedia: Utilise Expedia’s search tool to refine your preferences, including your budget, preferred location, and ideal type of accommodation. To discover the best prices and offers, sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel reservation in Santa Ana with your flights and activities through an Expedia package deal.

Find the best attractions near Santa Ana

Santa Ana, located in Panama City, offers a delightful mix of family-friendly, city-themed, and business-oriented activities. Visitors can explore captivating attractions such as hills, historical museums, and cathedrals, perfect for those seeking cultural immersion, scenic beauty, and outdoor adventures. Whether you're travelling with family or on a business trip, Santa Ana presents a variety of experiences that cater to every type of traveller.

  • Metropolitan Cathedral of Panama: This stunning cathedral, located 805m from Santa Ana, showcases a blend of architectural styles, reflecting Panama's rich cultural heritage. Its serene atmosphere and intricate details make it a must-visit for those seeking a glimpse into the nation's history.
  • Interoceanic Canal Museum: Situated 805m from Santa Ana, this museum offers an engaging exploration of the Panama Canal's history and significance. Interactive exhibits and informative displays provide a fascinating insight into this engineering marvel and its impact on global trade.
  • Ancon Hill: Just 966m from Santa Ana, Ancon Hill provides breathtaking views of the city and surrounding nature. Ideal for outdoor enthusiasts, the hill features trails that allow visitors to immerse themselves in Panamanian flora and fauna while enjoying panoramic scenery.

Best time to go to Santa Ana

The best time to visit Santa Ana is dependent on what kind of holiday you are seeking. April is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. November is its coolest month on average. At this time, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.8°F (26.0°C)No RainMostly SunnyAverageSlightly High
February79.2°F (26.2°C)No RainMostly SunnySlightly HighAverage
March79.7°F (26.5°C)No RainMostly SunnySlightly HighSlightly High
April80.4°F (26.9°C)Light RainMostly SunnyAverageSlightly High
May80.2°F (26.8°C)Frequent RainMostly CloudySlightly LowAverage
June79.9°F (26.6°C)Frequent RainMostly CloudySlightly LowAverage
July79.3°F (26.3°C)Frequent RainMostly CloudyAverageAverage
August79.2°F (26.2°C)Frequent RainMostly CloudyAverageAverage
September79.3°F (26.3°C)Frequent RainMostly CloudySlightly LowSlightly Low
October78.6°F (25.9°C)Frequent RainMostly CloudyAverageSlightly Low
November78.3°F (25.7°C)Frequent RainMostly CloudyAverageSlightly Low
December78.6°F (25.9°C)Light RainMostly CloudySlightly HighAverage

The nearest major airports for your trip to Santa Ana

Visiting Santa Ana is convenient with three major airports nearby. Panama City (PAC-Marcos A. Gelabert Intl.) is situated 3.2km away, with luxurious hotels such as W Panama and Bristol Panama, both offering 24-hour airport shuttles. Balboa (BLB-Panama Pacifico Intl.) is located 6.4km from Santa Ana, and the Sortis Hotel, Spa & Casino provides scheduled airport shuttle services. Lastly, Panama City (PTY-Tocumen Intl.) is 20.9km away, with hotels like Las Americas Golden Tower Panama and Hotel El Panama, both offering shuttle services to the airport. Each hotel ensures easy access to the respective airports for a seamless travel experience.

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighbourhood that travellers like for its seafood restaurants, shopping and parks. Are you looking for Santa Ana travel tips? Make sure that you visit Cinta Costera and Avenida Balboa while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Ana?
Expedia customers rank Hostal La Cigarra the highest for a stay in Santa Ana.
How many hotels can I expect to find in Santa Ana?
Expedia has 108 hotels and other accommodation options in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Santa Ana.
What is there to do in this Panama City neighbourhood?
If you're looking forward to a day of shopping in Santa Ana, consider Avenida Central or Avenida Balboa, and pick out the perfect souvenir. A visit to Cinta Costera is also worth the trip while you're discovering the neighbourhood. Albrook Shopping Mall, Amador Theater and Museum of Contemporary Art Panama are just a few of the places to visit in and around Santa Ana. When you're sightseeing in Panama City, Mi Pueblito and Iglesia de la Merced are also worth a stop.