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Our top choices for Santa Ana hotels

1. Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (73 reviews)
"Excellent staff, close to metro and embassies. A good location, good room for a great price. I would stay again. "
United Kingdom
Mark
The price is Rp560.320
Rp616.352 total
includes taxes & fees
4 Aug - 5 Aug
Hostal La Cigarra

2. Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (102 reviews)
"Always an amazing stay"
United States
chris
The price is Rp1.351.650
Rp2.027.475 total
includes taxes & fees
6 Aug - 7 Aug
Casco View Apartments

3. Hotel República

Hotel República
2.0 star property
Santa Ana
6.8 out of 10, (196 reviews)
"Good location. Walking distance to shops and public transport."
Canada
Danilo
The price is Rp527.143
Rp1.661.177 total
includes taxes & fees
4 Aug - 5 Aug
Hotel República

4. La Manzana Barrio Vivo by Wynwood

La Manzana Barrio Vivo by Wynwood
3.0 star property
Santa Ana
7.6 out of 10, Good, (18 reviews)
"Very clean and safe property"
United States
Javier Alberto Lindauer
The price is Rp1.260.352
Rp2.179.355 total
includes taxes & fees
11 Aug - 12 Aug
La Manzana Barrio Vivo by Wynwood

5. Hotel Riazor

Hotel Riazor
3.0 star property
Santa Ana
3.8 out of 10, (11 reviews)
"Rough neighborhood "
Canada
Del
The price is Rp486.594
Rp535.253 total
includes taxes & fees
4 Aug - 5 Aug
Hotel Riazor

6. Hotel Caracas - Casco Viejo

Hotel Caracas - Casco Viejo
3.0 star property
Santa Ana
9.0 out of 10, Wonderful, (2 reviews)
"It is what you would expect for the $30/ night. Clean bed, and room, a/c worked well, limited water for showers at times, limited hot water. Great location for walking around close to Casco Viejo."
United States
William
The price is Rp486.594
Rp535.253 total
includes taxes & fees
18 Aug - 19 Aug
Hotel Caracas - Casco Viejo

7. ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.0 out of 10, (11 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
The price is Rp442.260
Rp486.414 total
includes taxes & fees
29 Aug - 30 Aug
ART CASCO The Hotel

8. Hotel Caribe

Hotel Caribe
3.0 star property
Calidonia, 1.2 km from Santa Ana
7.6 out of 10, Good, (326 reviews)
"Nice clean, safe hotel in a great location."
Canada
James
The price is Rp761.607
Rp837.768 total
includes taxes & fees
10 Aug - 11 Aug
Hotel Caribe

9. Best Western El Dorado Panama Hotel

Best Western El Dorado Panama Hotel
3.0 star property
Bethania, 5.5 km from Santa Ana
9.0 out of 10, Wonderful, (759 reviews)
"The room was well kept, staff was very friendly, helpful and professional."
United States
Romain
The price is Rp1.773.365
Rp1.950.701 total
includes taxes & fees
7 Aug - 8 Aug
Best Western El Dorado Panama Hotel

10. Hotel Magnolia Boutique

Hotel Magnolia Boutique
2.0 star property
San Felipe, 0.7 km from Santa Ana
8.8 out of 10, Excellent, (497 reviews)
"Hotel located near shops and restaurants. Great for exploring Casco Viejo."
United States
ivania e
The price is Rp1.724.345
Rp1.896.816 total
includes taxes & fees
1 Sept - 2 Sept
Hotel Magnolia Boutique

11. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 3.4 km from Santa Ana
9.4 out of 10, Exceptional, (2,221 reviews)
"Great breakfast, location excellent, staff friendly and spacious room"
United States
Gilberto
The price is Rp1.861.111
Rp2.047.222 total
includes taxes & fees
28 Aug - 29 Aug
Plaza Paitilla Inn Hotel

12. Hotel Marparaiso

Hotel Marparaiso
3.0 star property
Calidonia, 1.7 km from Santa Ana
7.8 out of 10, Good, (191 reviews)
"The location was ideal for walking around."
United States
Erold
The price is Rp655.280
Rp720.880 total
includes taxes & fees
4 Aug - 5 Aug
Hotel Marparaiso

13. American Trade Hotel

American Trade Hotel
4.5 star property
San Felipe, 0.7 km from Santa Ana
9.4 out of 10, Exceptional, (785 reviews)
"A lovely friendly hotel with excellent staff"
United Kingdom
Ann
The price is Rp3.196.922
Rp3.516.614 total
includes taxes & fees
24 Aug - 25 Aug
American Trade Hotel

14. Tantalo Hotel

Tantalo Hotel
3.5 star property
San Felipe, 0.7 km from Santa Ana
8.8 out of 10, Excellent, (317 reviews)
"Great Location , helpful staff"
United States
David
The price is Rp1.681.993
Rp1.850.192 total
includes taxes & fees
9 Aug - 10 Aug
Tantalo Hotel

15. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
San Felipe, 0.9 km from Santa Ana
9.2 out of 10, Wonderful, (1,007 reviews)
"Love the breakfast and the rooms were amazing"
United States
querube
The price is Rp2.974.689
Rp3.272.158 total
includes taxes & fees
2 Sept - 3 Sept
Central Hotel Panama Casco Viejo

16. The District Hotel Panama

The District Hotel Panama
3.0 star property
El Cangrejo, 3.8 km from Santa Ana
7.4 out of 10, Good, (20 reviews)
"Great staff!"
United States
Angela
The price is Rp1.371.384
Rp1.508.522 total
includes taxes & fees
9 Aug - 10 Aug
The District Hotel Panama

17. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 3.6 km from Santa Ana
9.0 out of 10, Wonderful, (5,761 reviews)
"Great staff great hotel best breakfast"
United States
Vivian
The price is Rp2.377.972
Rp2.615.769 total
includes taxes & fees
2 Sept - 3 Sept
Hotel Riu Plaza Panama

18. Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
El Cangrejo, 3.4 km from Santa Ana
8.8 out of 10, Excellent, (571 reviews)
"Breakfast was great, location offered beautiful scenery with higher floor room."
United States
Solomon
The price is Rp1.666.953
Rp1.833.648 total
includes taxes & fees
9 Aug - 10 Aug
Torres de Alba Hotel & Suites

19. The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 3.2 km from Santa Ana
9.2 out of 10, Wonderful, (1,211 reviews)
"This is an exceptionally nice hotel, location, service and amenities were all on point."
United States
Geraldeen
The price is Rp1.598.544
Rp1.758.398 total
includes taxes & fees
17 Aug - 18 Aug
The Executive Hotel

20. La Concordia Boutique Hotel

La Concordia Boutique Hotel
4.0 star property
San Felipe, 0.5 km from Santa Ana
9.6 out of 10, Exceptional, (230 reviews)
"Very nice rooms and bathrooms. Great location in Casco Viejo"
Canada
Shrinand
The price is Rp3.632.197
Rp3.995.417 total
includes taxes & fees
9 Aug - 10 Aug
La Concordia Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, pool loungers
Casco View Apartments
3.5 star property
9.0
Wonderful
102 reviews
View
Bar (on property)
Hostal La Cigarra
2.0 star property
7.6
Good
73 reviews
View
Apartment (20) | Iron/ironing board, free WiFi, bed sheets
La Manzana Barrio Vivo by Wynwood
3.0 star property
7.6
Good
18 reviews
View
Twin Room | In-room safe, desk, soundproofing, free WiFi
Hotel República
2.0 star property
6.8
196 reviews
View
Exterior
Hotel Caracas - Casco Viejo
3.0 star property
9.0
Wonderful
2 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Pacific Center while you're in town.

Top Santa Ana Hotel Reviews

Find out more about Santa Ana

Top reasons to visit Santa Ana

  • Vibrant Walking Tours: Explore Santa Ana through free walking tours led by knowledgeable locals, offering insights into the culture and history of the neighbourhood.
  • Historical Attractions: Visit notable sites such as the Santa Ana Church and the nearby San Miguel, enriching your experience with the area's historical significance.
  • Family-Friendly Atmosphere: Santa Ana provides a welcoming environment for families, making it an ideal destination for both leisure and business-themed holidays.
  • Diverse Accommodation: Choose from a variety of accommodations, including pet-friendly hotels and comfortable apartments tailored to suit all travellers.
  • Local Culture: Immerse yourself in the warm Panamanian culture, characterised by friendly locals and a lively atmosphere.

Find great hotels near Santa Ana

Discover the charm of Santa Ana, a vibrant area in Panama City, offering a diverse selection of accommodations to suit every traveller's needs. From inviting hotels to comfortable apartments, you’ll find pet-friendly options and facilities tailored for business and leisure. Experience the unique city-themed vibes and enjoy your stay in this captivating destination, with convenient access to Panama’s rich culture and attractions.

  • American Trade Hotel: The American Trade Hotel is a charming 4.5-star accommodation that captures the essence of romance and adventure. With a guest rating of 9.4 out of 10, this hotel is located 644m from Santa Ana. It is ideally suited for families and couples seeking both relaxation and excitement. Guests can indulge in various adventure sports, including nearby Segway tours, bicycle rentals, and hiking. The hotel offers amenities for children, such as breakfast options and travel cribs. Guests can enjoy delightful garden views from the restaurant and savour romantic dining experiences with room service and champagne services. For those looking to unwind, the hotel features outdoor pools and in-room massage services, making it a perfect getaway for relaxation.
  • Sofitel Legend Casco Viejo, Panama City: With a prestigious 5-star rating and an impressive guest rating of 9.8 out of 10, the Sofitel Legend Casco Viejo is a luxurious haven located 1km from Santa Ana. This elegant property caters to business travellers and those seeking a rejuvenating spa experience. Guests can indulge in a comprehensive range of spa services, including body scrubs and treatments, alongside a serene pool area with sun loungers. The hotel’s sophisticated atmosphere and high-end amenities create a refined environment perfect for unwinding after a busy day in the city.
  • Innfiniti Hotel & Suites: The Innfiniti Hotel & Suites offers a 3.5-star experience in the heart of the city, situated 1km from Santa Ana. This hotel caters to business travellers and those looking to immerse themselves in the urban landscape. Its central location allows easy access to local attractions and business centres, making it a convenient choice for professionals. The hotel features modern accommodations and essential amenities, ensuring guests have a comfortable and efficient stay during their visit to Panama City.

Where to stay near Santa Ana

Santa Ana, a vibrant neighbourhood in Panamá Province, offers a delightful blend of family-friendly atmospheres and business vibes. During your visit, immerse yourself in the warm Panamanian culture, where friendly locals enhance the lively experience. Explore nearby areas to uncover the best parts of Panama, characterised by luxurious relaxation and a welcoming environment. Whether you're seeking adventure or tranquillity, Santa Ana promises a memorable getaway.

  • Panama City: As the bustling capital of Panama, Panama City is a vibrant metropolis that blends modernity with rich history. Situated in close proximity to Santa Ana, the city offers a plethora of experiences for travellers. With consistent visitor numbers throughout the year, the city showcases a diverse cultural landscape, making it ideal for family, business, or city-themed adventures. Notably, you can explore various shopping centres and bustling malls, while local landmarks such as beaches and parks provide a refreshing escape from the urban hustle.
  • Casco Viejo: Located a mere 644m from Santa Ana, Casco Viejo is a historic neighbourhood that captures the essence of Panama's colonial past. This UNESCO World Heritage site is renowned for its charming streets, colonial architecture, and vibrant atmosphere. Visitors flock here for family-friendly activities, business meetings, and immersive city experiences. With its proximity to beaches and parks, plus an array of shopping options, Casco Viejo is an idyllic spot to enjoy leisurely strolls and cultural explorations.
  • Barrio Chino: Just 322m from Santa Ana, Barrio Chino, or Chinatown, is a lively neighbourhood that reflects the cultural diversity of Panama City. This vibrant area attracts visitors seeking business, family, and city-themed experiences. With its array of shopping centres and malls, it’s a haven for those looking to indulge in retail therapy. Additionally, the local museums and research facilities add an educational touch, making Barrio Chino a fascinating destination to explore the confluence of cultures in Panama.

Things to do near Santa Ana

Shopping

Nearby, you can explore the vibrant Mercado de Santa Ana, where local artisans offer unique crafts and souvenirs. For a more modern experience, visit Multiplaza Pacific Mall, featuring a range of international brands and local boutiques, perfect for finding gifts to take home.

Recreation

Wellness Centre Santa Ana offers a tranquil environment with holistic treatments, yoga classes, and meditation sessions to rejuvenate your mind and body. Nearby, Parque Natural Metropolitano provides scenic trails for hiking and birdwatching, allowing you to connect with nature while enjoying the beauty of Panama's diverse wildlife.

Adventure

Gatun Eco Adventures offers an exhilarating zipline and ropes course experience, located 48km from Santa Ana. Soar through the treetops and navigate challenging obstacles, immersing yourself in the lush surroundings and embracing the thrill of this outdoor adventure.

Nightlife

Explore the vibrant nightlife in Santa Ana by visiting Casa de la Cerveza for a variety of local brews. For a lively atmosphere, head to Bar El Bongo, where you can dance to rhythmic music and enjoy the company of locals and fellow travellers alike.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Ana

For a budget-friendly trip to Santa Ana, consider visiting between September and November when accommodation prices are lower. Tuesdays are the cheapest days to stay, while Saturdays tend to be more expensive. Utilise Expedia’s search tool to find the best deals based on your budget and preferences, and consider booking a package that combines flights and hotels for additional savings. Look for app deals and instant savings to further cut costs. Additionally, explore free activities in the area to make the most of your visit without overspending.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Santa Ana are September to November, where the prices are slightly lower. This is in comparison to January and March to April, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Santa Ana is Tuesday. The most expensive day to stay around Santa Ana is Saturday.
  • Find cheap hotels on Expedia: Utilise Expedia’s search tool to refine your preferences, including your budget, preferred location, and ideal type of accommodation. To discover the best prices and offers, sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel reservation in Santa Ana with your flights and activities through an Expedia package deal.

Find the best attractions near Santa Ana

Santa Ana in Panama City is an ideal destination for family and business-themed vacations, offering a delightful mix of culture and outdoor experiences. Visitors can explore local attractions such as the Santa Ana Church, Iglesia Santa Ana, and the nearby San Miguel, along with scenic hills and history museums that enrich the area’s historical significance. Whether you're seeking a cultural immersion or a leisurely day out, Santa Ana has something for everyone.

  • Metropolitan Cathedral of Panama: This stunning cathedral, located 805m from Santa Ana, showcases a blend of architectural styles, reflecting the rich cultural heritage of Panama. Its impressive façade and ornate interiors make it a significant religious and historical site.
  • Interoceanic Canal Museum: Situated 805m away, this museum offers fascinating insights into the history and significance of the Panama Canal. Visitors can explore interactive exhibits that capture the spirit of innovation and engineering behind this monumental achievement.
  • Independence Square: Also 805m from Santa Ana, this vibrant piazza serves as a gathering place, steeped in history and culture. Surrounded by colonial architecture, it is a perfect spot to immerse oneself in the local atmosphere and enjoy leisurely strolls.

Best time to go to Santa Ana

The best time to visit Santa Ana can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Santa Ana falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature around Santa Ana falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January78.8°F (26.0°C)No RainMostly SunnyAverageSlightly High
February79.2°F (26.2°C)No RainMostly SunnySlightly HighAverage
March79.7°F (26.5°C)No RainMostly SunnySlightly HighSlightly High
April80.4°F (26.9°C)Light RainMostly SunnyAverageSlightly High
May80.2°F (26.8°C)Frequent RainMostly CloudySlightly LowAverage
June79.9°F (26.6°C)Frequent RainMostly CloudySlightly LowAverage
July79.3°F (26.3°C)Frequent RainMostly CloudyAverageAverage
August79.2°F (26.2°C)Frequent RainMostly CloudyAverageAverage
September79.3°F (26.3°C)Frequent RainMostly CloudySlightly LowSlightly Low
October78.6°F (25.9°C)Frequent RainMostly CloudyAverageSlightly Low
November78.3°F (25.7°C)Frequent RainMostly CloudyAverageSlightly Low
December78.6°F (25.9°C)Light RainMostly CloudySlightly HighAverage

The nearest major airports for your trip to Santa Ana

Reaching Santa Ana, Panama, is convenient with three major airports nearby. Panama City (PAC-Marcos A. Gelabert Intl.) is located 3km from Santa Ana, with luxurious hotels such as Hilton Panama and Sofitel Legend Casco Viejo, both offering various airport transportation services. Balboa (BLB-Panama Pacifico Intl.) is 6km away, featuring The Westin Playa Bonita Panama among other upscale options. Lastly, Panama City (PTY-Tocumen Intl.) is 21km from Santa Ana, where guests can stay at The Santa Maria, A Luxury Collection Hotel, with accessible airport shuttles. Each airport provides a range of transport services to ensure a seamless journey.

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighbourhood that travellers like for its seafood restaurants, shopping and parks. Are you looking for Santa Ana travel tips? Make sure that you visit Avenida Balboa and El Machetazo Santa Ana while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Ana?
Based on our traveller data, Casco View Apartments is one of the top choices for your stay in Santa Ana. This condo is a short 8-minute walk from Avenida Balboa, and it offers an outdoor pool and in-room kitchens.
How many hotels can I expect to find in Santa Ana?
Expedia has 122 hotels and other accommodation options in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Santa Ana.
What is there to do in this Panama City neighbourhood?
If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana or Avenida Balboa, and pick out the perfect souvenir. When you're sightseeing in Panama City, Albrook Shopping Mall and Avenida Central are also worth a stop.