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Our top choices for Santa Ana hotels

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (92 reviews)
"yes there was laundryroom, iron and nice pool. the stay was very good"
United States
melvin
The price is Rp1.445.380
Rp2.106.248 total
includes taxes & fees
4 May - 5 May
Casco View Apartments

La Manzana by Wynwood House

La Manzana by Wynwood House
3.0 star property
Santa Ana
7.4 out of 10, Good, (16 reviews)
"Very clean and safe property"
United States
Javier Alberto Lindauer
The price is Rp1.082.572
Rp1.664.132 total
includes taxes & fees
3 May - 4 May
La Manzana by Wynwood House

Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (70 reviews)
"Excellent staff, close to metro and embassies. A good location, good room for a great price. I would stay again. "
United Kingdom
Mark
The price is Rp492.861
Rp542.147 total
includes taxes & fees
29 Apr - 30 Apr
Hostal La Cigarra

Hotel República

Hotel República
2.0 star property
Santa Ana
6.6 out of 10, (189 reviews)
"It's meant for a short stay, close to Casco Viejo and coast line. Clean bed and bathroom. Needs some maintenance. Beware, there's no hot water if that's a deal breaker for you."
United States
Mario
The price is Rp503.422
Rp553.850 total
includes taxes & fees
29 Apr - 30 Apr
Hotel República

ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.0 out of 10, (11 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
The price is Rp634.341
Rp697.775 total
includes taxes & fees
29 Apr - 30 Apr
ART CASCO The Hotel

Hotel Riazor

Hotel Riazor
3.0 star property
Santa Ana
3.8 out of 10, (11 reviews)
"Rough neighborhood "
Canada
Del
Hotel Riazor

ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport
2.0 star property
20.5 km from Santa Ana
8.8 out of 10, Excellent, (109 reviews)
"Great place to stay with plenty of places nearby for food and drinks"
United States
Thomas
The price is Rp2.065.320
Rp2.680.786 total
includes taxes & fees
29 Apr - 30 Apr
ORHO HOTEL BOUTIQUE PANAMA Airport

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
21.1 km from Santa Ana
8.6 out of 10, Excellent, (2,505 reviews)
"Good place to stay while traveling."
United States
Annery
The price is Rp2.185.797
Rp2.517.969 total
includes taxes & fees
5 May - 6 May
Crowne Plaza Panama Airport by IHG

Villa Caprichosa

Villa Caprichosa
2.5 star property
18.3 km from Santa Ana
9.8 out of 10, Exceptional, (66 reviews)
"What a beautiful place! A dream come true. "
United States
Mariela
The price is Rp3.291.604
Rp3.620.764 total
includes taxes & fees
2 May - 3 May
Villa Caprichosa

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
19.8 km from Santa Ana
8.4 out of 10, Very good, (1,849 reviews)
"Friendly staff."
Canada
Samuel
The price is Rp1.882.023
Rp2.070.225 total
includes taxes & fees
16 May - 17 May
Riande Aeropuerto Hotel & Casino

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este, 10.2 km from Santa Ana
9.4 out of 10, Exceptional, (278 reviews)
"Very good place to stay and safe place..!"
United States
Somnueg
The price is Rp2.065.320
Rp2.271.852 total
includes taxes & fees
30 Apr - 1 May
Arcadia Condo Suites

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
14.7 km from Santa Ana
9.0 out of 10, Wonderful, (1,003 reviews)
"Great service, very comfortable beds, truly excellent breakfast manager and staff. "
United States
Elizabeth
The price is Rp1.594.599
Rp1.754.059 total
includes taxes & fees
23 May - 24 May
Courtyard by Marriott Panama Metromall

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz, 12.7 km from Santa Ana
9.6 out of 10, Exceptional, (688 reviews)
"Breakfast was exceptional, everything you could think of was available. The spa was great and the staff 10/10"
United States
Aeon
The price is Rp4.634.062
Rp5.097.554 total
includes taxes & fees
8 May - 9 May
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Westin Panama

The Westin Panama
4.0 star property
Costa del Este, 9.4 km from Santa Ana
9.0 out of 10, Wonderful, (330 reviews)
"Excellent stay, friendly and attentive staff, beautiful property!!!"
United States
Erica
The price is Rp3.833.578
Rp4.216.936 total
includes taxes & fees
2 May - 3 May
The Westin Panama

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco, 5.7 km from Santa Ana
8.6 out of 10, Excellent, (1,001 reviews)
"Everything was great, really nice stay"
United States
Hary
The price is Rp2.307.995
Rp2.538.795 total
includes taxes & fees
17 May - 18 May
Sheraton Grand Panama

The Beach House

The Beach House
3.0 star property
Amador, 4.8 km from Santa Ana
8.4 out of 10, Very good, (432 reviews)
"Everting was clean and good nice place to stay "
United States
Kristine
The price is Rp1.280.326
Rp1.408.376 total
includes taxes & fees
4 May - 5 May
The Beach House

Taboga Palace Spa Hotel

Taboga Palace Spa Hotel
3.5 star property
17.7 km from Santa Ana
9.4 out of 10, Exceptional, (51 reviews)
"My room was perfect just steps from the pool with a great view of the ocean. Dave was a great host and help make my stay truly enjoyable. "
United States
James
The price is Rp2.237.430
Rp2.461.173 total
includes taxes & fees
30 Apr - 1 May
Taboga Palace Spa Hotel

MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel
3.5 star property
Amador, 4.8 km from Santa Ana
8.2 out of 10, Very good, (249 reviews)
"The breakfast was good and lots of parking in a safe place "
United States
Tessa
The price is Rp1.723.165
Rp1.895.447 total
includes taxes & fees
30 Apr - 1 May
MARINN Tropical Vibes Hotel

Hotel Bardot Boutique

Hotel Bardot Boutique
3.0 star property
San Felipe, 1.1 km from Santa Ana
9.6 out of 10, Exceptional, (22 reviews)
"Excellent location in the most tourist part of Panama City, Casco Antiguo. Safe area, local to everything, and a beautiful hotel. "
United States
Fatin
The price is Rp2.104.303
Rp2.314.733 total
includes taxes & fees
4 May - 5 May
Hotel Bardot Boutique

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Campo Alegre, 3.4 km from Santa Ana
8.6 out of 10, Excellent, (200 reviews)
"It's a very nice hotel and the staff is very nice as well"
United States
Shaied
The price is Rp2.185.797
Rp2.404.377 total
includes taxes & fees
5 May - 6 May
Renaissance Panama City Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, pool loungers
Casco View Apartments
3.5 star property
9.0
Wonderful
92 reviews
View
Bar (on property)
Hostal La Cigarra
2.0 star property
7.6
Good
70 reviews
View
Apartment (20) | Iron/ironing board, free WiFi, bed sheets
La Manzana by Wynwood House
3.0 star property
7.4
Good
16 reviews
View
Double Room | View from room
Hotel República
2.0 star property
6.6
189 reviews
View
Front of property
ART CASCO The Hotel
2.0 star property
6.0
11 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

Top Santa Ana Hotel Reviews

Find out more about Santa Ana

Top reasons to visit Santa Ana

  • Vibrant Shopping Centres: Santa Ana boasts a range of shopping venues, perfect for family outings and leisurely exploration.
  • Scenic Avenida Balboa: Enjoy breathtaking views and impressive architecture along this iconic promenade.
  • Cultural Attractions: Discover historical museums and cathedrals that offer a glimpse into Panama's rich heritage.
  • Outdoor Activities: Engage in bike lanes, boat tours, and city walks for an adventurous experience.
  • Diverse Accommodation: Choose from various lodging options catering to both leisure and business travellers, ensuring a comfortable stay.

Find great hotels near Santa Ana

In Santa Ana, you’ll discover a delightful selection of accommodation options, ranging from hotels to apartments, perfect for every type of traveller. Whether you're seeking a city-themed retreat, a pet-friendly haven, or a comfortable base for business travel, Santa Ana has you covered. Many establishments offer essential amenities such as air conditioning and all-inclusive options, ensuring a pleasant stay in this charming area of Panama City.

  • Residencial & Hotel Palazzo: Experience the vibrant city life at Residencial & Hotel Palazzo, a comfortable 3-star hotel located just 1.4km from Santa Ana. Ideal for urban adventurers, this property offers a city-themed vacation experience with easy access to local attractions. Guests can enjoy well-appointed rooms and a welcoming atmosphere, making it a great base for exploring the bustling streets of Panama City.
  • Tantalo Hotel: Positioned a mere 644m from Santa Ana, the 3.5-star Tantalo Hotel is perfect for both business travellers and those seeking an exciting city escape. With a chic, contemporary design, this hotel features modern amenities and a vibrant social scene, including a rooftop bar that offers stunning views of the city skyline. Its prime location allows guests to immerse themselves in the local culture and nightlife, ensuring a memorable stay.
  • La Concordia Boutique Hotel: For a family-friendly and pet-friendly experience, look no further than La Concordia Boutique Hotel, located just 483m from Santa Ana. This 4-star establishment caters to families with children, offering amenities such as babysitting services and high chairs. The hotel is also welcoming to pets, with specific policies in place to ensure a comfortable stay for all guests. With its charming atmosphere and focus on family care, La Concordia is a delightful choice for those travelling with loved ones.

Where to stay near Santa Ana

Santa Ana, a vibrant neighbourhood in Panama City, offers an array of experiences for all types of travellers. Explore the stunning Avenida Balboa with its breathtaking views and impressive architectural elements. The friendly atmosphere and family-friendly options make it perfect for a leisurely visit. Nearby, you can discover beautiful places that reflect the charm of an Asian city, providing a unique blend of relaxation and luxury. Santa Ana truly captures the essence of Panamanian hospitality.

  • Panama City: As the vibrant capital of Panama, Panama City serves as a gateway to the rich culture and history of the country. Located in close proximity to Santa Ana, this bustling metropolis offers a mix of modern skyscrapers and historical sites. Visitors can indulge in shopping at various centres and enjoy the local beaches, parks, and lively streets. The city is particularly popular among families and business travellers, and with its year-round appeal, there’s always something to experience, whether it’s the vibrant nightlife or the serene parks.
  • Casco Viejo: A mere 644m from Santa Ana, Casco Viejo is a UNESCO World Heritage site renowned for its colonial charm and historical significance. This picturesque neighbourhood is filled with cobblestone streets, colourful buildings, and a variety of shops and restaurants. Popular for family outings and cultural explorations, visitors can enjoy relaxing at parks, shopping in the local area, or soaking up the sun at nearby beaches. The atmosphere here is energetic, particularly during peak seasons in January and March to April, making it a must-visit destination.
  • Barrio Chino: Just 322m from Santa Ana, Barrio Chino, or Chinatown, is a vibrant neighbourhood that celebrates Chinese culture within Panama. This area boasts a variety of shopping options, from bustling markets to modern shopping centres, as well as theatres showcasing local performances. Visitors can immerse themselves in the rich history at nearby museums and historic places of worship. With its peak visitor arrivals in February to March and December, Barrio Chino offers a unique blend of cultural experiences, making it an intriguing stop on your journey.

Things to do near Santa Ana

Santa Ana in Panama City is perfect for family, city, and business-themed vacations. Visitors can explore vibrant shopping centres and areas, while also enjoying activities such as bike lanes, boat tours, and city walks. Adventure seekers will find plenty to do, making it an ideal destination for those looking to experience the charm and excitement of Panama City.

Shopping

In Santa Ana, you can enjoy shopping at Albrook Shopping Mall, just 1.6km away, offering a vibrant mix of entertainment and family-friendly options. For a local experience, visit Avenida Central, 483m away, featuring a lively atmosphere perfect for souvenirs and gifts.

Recreation

Experience the vibrant atmosphere at Maracana Stadium, only 1.3km from Santa Ana, where you can enjoy exciting sports events. For a broader range of activities, Estadio Nacional Rod Carew and Estadio Rommel Fernandez, located 6 and 11.3km away respectively, also offer thrilling sports experiences.

Adventure

Embark on the Honeycreeper Ridge Trail, located 43.5km from Santa Ana, where you'll encounter breathtaking scenery and a true outdoor adventure. Experience the thrill of Gatun Eco Adventures, a zipline ropes course 48.3km away, offering exhilarating rides amidst lush surroundings and vibrant adventure vibes.

Nightlife

Experience the vibrant nightlife in Santa Ana by visiting the National Theatre, offering a blend of romance and culture just 966m away. For more theatrical charm, check out Anita Villalaz Theatre, located 1.3km away, or enjoy a show at Amador Theatre, a mere 483m from Santa Ana.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Ana

For a budget-friendly trip to Santa Ana, consider visiting between September and November when accommodation prices are lower. Tuesdays are the cheapest days to stay, while Saturdays tend to be more expensive. Utilise Expedia’s search tool to find the best deals based on your budget and preferences, and consider booking a package that combines flights and hotels for additional savings. Look for app deals and instant savings to further cut costs. Additionally, explore free activities in the area to make the most of your visit without overspending.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Santa Ana are September to November, where the prices are slightly lower. This is in comparison to January and March to April, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Santa Ana is Tuesday. The most expensive day to stay around Santa Ana is Saturday.
  • Find cheap hotels on Expedia: Utilise Expedia’s search tool to refine your preferences, including your budget, preferred location, and ideal type of accommodation. To discover the best prices and offers, sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel reservation in Santa Ana with your flights and activities through an Expedia package deal.

Find the best attractions near Santa Ana

Santa Ana, located in Panama City, offers a delightful mix of family-friendly, city-themed, and business-oriented activities. Visitors can explore captivating attractions such as hills, historical museums, and cathedrals, perfect for those seeking cultural immersion, scenic beauty, and outdoor adventures. Whether you're travelling with family or on a business trip, Santa Ana presents a variety of experiences that cater to every type of traveller.

  • Metropolitan Cathedral of Panama: This stunning cathedral, located 805m from Santa Ana, showcases a blend of architectural styles, reflecting Panama's rich cultural heritage. Its serene atmosphere and intricate details make it a must-visit for those seeking a glimpse into the nation's history.
  • Interoceanic Canal Museum: Situated 805m from Santa Ana, this museum offers an engaging exploration of the Panama Canal's history and significance. Interactive exhibits and informative displays provide a fascinating insight into this engineering marvel and its impact on global trade.
  • Ancon Hill: Just 966m from Santa Ana, Ancon Hill provides breathtaking views of the city and surrounding nature. Ideal for outdoor enthusiasts, the hill features trails that allow visitors to immerse themselves in Panamanian flora and fauna while enjoying panoramic scenery.

Best time to go to Santa Ana

The best time to visit Santa Ana is dependent on what kind of holiday you are seeking. April is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. November is its coolest month on average. At this time, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.8°F (26.0°C)No RainMostly SunnyAverageSlightly High
February79.2°F (26.2°C)No RainMostly SunnySlightly HighAverage
March79.7°F (26.5°C)No RainMostly SunnySlightly HighSlightly High
April80.4°F (26.9°C)Light RainMostly SunnyAverageSlightly High
May80.2°F (26.8°C)Frequent RainMostly CloudySlightly LowAverage
June79.9°F (26.6°C)Frequent RainMostly CloudySlightly LowAverage
July79.3°F (26.3°C)Frequent RainMostly CloudyAverageAverage
August79.2°F (26.2°C)Frequent RainMostly CloudyAverageAverage
September79.3°F (26.3°C)Frequent RainMostly CloudySlightly LowSlightly Low
October78.6°F (25.9°C)Frequent RainMostly CloudyAverageSlightly Low
November78.3°F (25.7°C)Frequent RainMostly CloudyAverageSlightly Low
December78.6°F (25.9°C)Light RainMostly CloudySlightly HighAverage

The nearest major airports for your trip to Santa Ana

Visiting Santa Ana is convenient with three major airports nearby. Panama City (PAC-Marcos A. Gelabert Intl.) is situated 3.2km away, with luxurious hotels such as W Panama and Bristol Panama, both offering 24-hour airport shuttles. Balboa (BLB-Panama Pacifico Intl.) is located 6.4km from Santa Ana, and the Sortis Hotel, Spa & Casino provides scheduled airport shuttle services. Lastly, Panama City (PTY-Tocumen Intl.) is 20.9km away, with hotels like Las Americas Golden Tower Panama and Hotel El Panama, both offering shuttle services to the airport. Each hotel ensures easy access to the respective airports for a seamless travel experience.

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighbourhood that travellers like for its seafood restaurants, shopping and parks. Are you looking for Santa Ana travel tips? Make sure that you visit Avenida Balboa and El Machetazo Santa Ana while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Ana?
Based on our traveller data, Casco View Apartments is one of the top choices for your stay in Santa Ana. This condo is a short 8-minute walk from Avenida Balboa, and it offers an outdoor pool and in-room kitchens.
How many hotels can I expect to find in Santa Ana?
Expedia has 119 hotels and other accommodation options in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Santa Ana.
What is there to do in this Panama City neighbourhood?
If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana or Avenida Balboa, and pick out the perfect souvenir. When you're sightseeing in Panama City, Albrook Shopping Mall and Avenida Central are also worth a stop.