Search Hotels in Santa María, Oaxaca

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9 Dec - 10 Dec
Tomorrow
10 Dec - 11 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

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Our top choices for Santa María hotels

Exterior
One Oaxaca Centro Hotel

One Oaxaca Centro Hotel

3.0 star property
Ruta Independencia, 2.5 km from Santa María
8.8 out of 10, Excellent, (1002)
"Very good hotel"
United States
Hugo
The price is Rp1.331.840
Rp1.584.890 total
includes taxes & fees
15 Dec - 16 Dec
One Oaxaca Centro Hotel
Building design
Quinta Real Oaxaca

Quinta Real Oaxaca

4.5 star property
Ruta Independencia, 1.9 km from Santa María
9.6 out of 10, Exceptional, (1003)
"We loved everything about our stay at Quinta Real in Oaxaca, highly recommend, would definitely stay again!"
United States
Valerie
The price is Rp4.895.050
Rp5.825.110 total
includes taxes & fees
10 Dec - 11 Dec
Quinta Real Oaxaca
Restaurant
Capital O Posada La Casa De La Tia, Oaxaca

Capital O Posada La Casa De La Tia, Oaxaca

3.0 star property
Ruta Independencia, 2 km from Santa María
7.8 out of 10, Good, (195)
"You can walk around downtown "
United States
GORGONIO
The price is Rp739.629
Rp961.518 total
includes taxes & fees
7 Jan - 8 Jan 2026
Capital O Posada La Casa De La Tia, Oaxaca
Garden
Hotel Hacienda

Hotel Hacienda

3.5 star property
3.1 km from Santa María
9.0 out of 10, Wonderful, (1005)
"Super friendly and helpful staff, clean room and very good food at the restaurant!!!"
Mexico
Carlos
The price is Rp934.420
Rp1.111.967 total
includes taxes & fees
12 Dec - 13 Dec
Hotel Hacienda
Terrace/patio
LePetit

LePetit

2.5 star property
Ruta Independencia, 2.2 km from Santa María
9.4 out of 10, Exceptional, (21)
"The staff is amazing"
United States
Carmen
The price is Rp1.538.910
Rp1.831.306 total
includes taxes & fees
10 Dec - 11 Dec
LePetit
Outdoor dining
Happy Express Hotel

Happy Express Hotel

2.5 star property
Oaxaca Centro, 1.8 km from Santa María
9.0 out of 10, Wonderful, (319)
"Nice and clean close to everything easy walking Quiet, comfortable bed and pillows "
United States
MIRIAM
Happy Express Hotel
Terrace/patio
Casa de los Frailes Hotel

Casa de los Frailes Hotel

3.0 star property
Ruta Independencia, 1.9 km from Santa María
9.2 out of 10, Wonderful, (363)
"Good location close to the centre but on a fairly quiet street. Large rooms, decent shower. "
United Kingdom
Richard
The price is Rp1.164.007
Rp1.385.167 total
includes taxes & fees
10 Dec - 11 Dec
Casa de los Frailes Hotel
Outdoor pool
Hotel Victoria Oaxaca

Hotel Victoria Oaxaca

3.5 star property
0.8 km from Santa María
8.8 out of 10, Excellent, (1004)
"Good breakfast at the restaurant. Nice setting. Friendly front desk staff."
Canada
David
The price is Rp1.211.011
Rp1.441.101 total
includes taxes & fees
16 Dec - 17 Dec
Hotel Victoria Oaxaca
Courtyard
Grand Fiesta Americana Oaxaca

Grand Fiesta Americana Oaxaca

5.0 star property
Ruta Independencia, 2 km from Santa María
9.6 out of 10, Exceptional, (665)
"Great staff, beautiful rooms, wonderful food. Also perfect location."
United States
John Lester
The price is Rp3.612.616
Rp4.299.013 total
includes taxes & fees
15 Dec - 16 Dec
Grand Fiesta Americana Oaxaca
Lunch and dinner served
Casa De Sierra Azul

Casa De Sierra Azul

3.5 star property
Oaxaca Centro, 2.2 km from Santa María
9.2 out of 10, Wonderful, (898)
"Hospitality was the best. Great location with a lot of shops and Zocalo at walkable distance. rooms were beautiful and comfortable "
United States
Brian
Casa De Sierra Azul
Exterior
Casa Los Cantaros Hotel Boutique

Casa Los Cantaros Hotel Boutique

3.5 star property
Reforma, 1.8 km from Santa María
9.4 out of 10, Exceptional, (264)
"Nice staff and huge room with all the amenities."
United States
Celia
The price is Rp1.211.011
Rp1.441.103 total
includes taxes & fees
10 Dec - 11 Dec
Casa Los Cantaros Hotel Boutique
Exterior
Hotel Boutique Parador San Miguel

Hotel Boutique Parador San Miguel

3.0 star property
Ruta Independencia, 1.8 km from Santa María
9.4 out of 10, Exceptional, (777)
"Was one of the best hotels, clean the people were awesome and helped whenever needed"
United States
Asokaraj
The price is Rp2.129.141
Rp2.533.678 total
includes taxes & fees
7 Jan - 8 Jan 2026
Hotel Boutique Parador San Miguel
Reception
Marqués Oaxaca - Hotel

Marqués Oaxaca - Hotel

2.0 star property
2.5 km from Santa María
7.2 out of 10, Good, (104)
"Staff was friendly, & helpful. The location was perfect! Everything was in walking distance, but if you needed a cab the hotel gladly arranged one for you. "
United States
Daisy
The price is Rp828.731
Rp986.195 total
includes taxes & fees
14 Dec - 15 Dec
Marqués Oaxaca - Hotel
Terrace/patio
Hotel Danibaan

Hotel Danibaan

3.0 star property
Del Ex-marquezado, 1.1 km from Santa María
9.4 out of 10, Exceptional, (169)
"Clean Gustavo and staff were very nice and i slept so well. It felt like home away from home. "
United States
Marisol
The price is Rp912.180
Rp1.085.494 total
includes taxes & fees
11 Dec - 12 Dec
Hotel Danibaan
Property grounds
Hotel Trebol

Hotel Trebol

3.0 star property
Oaxaca Centro, 2.1 km from Santa María
9.2 out of 10, Wonderful, (1007)
"Amazing staff and accommodations will be coming back"
United States
Christopher Joel Romo
The price is Rp1.944.180
Rp2.313.574 total
includes taxes & fees
5 Jan - 6 Jan 2026
Hotel Trebol
Coffee shop
Hotel Boutique Naura Centro

Hotel Boutique Naura Centro

3.5 star property
Oaxaca Centro, 2.2 km from Santa María
9.2 out of 10, Wonderful, (978)
"wonderful staff and great amenities. Delicious food in their restaurant + cafe."
United States
Edna
Hotel Boutique Naura Centro
Hallway
Casa Antonieta

Casa Antonieta

3.5 star property
Oaxaca Centro, 2.1 km from Santa María
10.0 out of 10, Exceptional, (59)
"A lovely spot all around. "
Canada
Kelly
The price is Rp5.240.117
Rp6.235.740 total
includes taxes & fees
10 Dec - 11 Dec
Casa Antonieta
Standard Double Room, 1 Double Bed | Desk, laptop workspace, free WiFi, bed sheets
HOTEL POSADA DON MATIAS

HOTEL POSADA DON MATIAS

2.0 star property
Oaxaca Centro, 2 km from Santa María
9.0 out of 10, Wonderful, (189)
"Nice and simple hotel right in the city center. Easy access to sights downtown. Safe and nice and cool during the day. "
Canada
Rachel
The price is Rp559.983
Rp666.385 total
includes taxes & fees
7 Jan - 8 Jan 2026
HOTEL POSADA DON MATIAS
Exterior
Hotel Los Ciruelos

Hotel Los Ciruelos

2.5 star property
Reforma, 2 km from Santa María
8.6 out of 10, Excellent, (66)
"A good place to stay for the neighborhood, a lot of good things around the place "
Canada
Josimar
Hotel Los Ciruelos
Terrace/patio
Hotel Real Alma

Hotel Real Alma

3.5 star property
Oaxaca Centro, 1.8 km from Santa María
9.0 out of 10, Wonderful, (406)
"Cozy and comfortable hotel. Very clean and staff was very nice and friendly ready to help you with any questions."
United States
Julia
The price is Rp1.624.124
Rp1.932.708 total
includes taxes & fees
20 Dec - 21 Dec
Hotel Real Alma
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa María

Find the best Santa María areas for the activities you enjoy most.
Oaxaca showing a city
Photo by PhotoJoy
Open Photo by PhotoJoy

Oaxaca Centro

Churches, museums and art galleries are some highlights of Oaxaca Centro. Make a stop by Macedonio Alcalá Theater or Oaxaca Textile Museum while you're exploring.

Ruta Independencia

While visiting Ruta Independencia, you might make a stop by sights like Oaxaca Ethnobotanical Garden and Jardín Etnobotánico.

Jalatlaco

While Jalatlaco isn't home to many top sights, El Llano Park and Oaxaca Ethnobotanical Garden are some notable places to visit nearby.

Reforma

While visiting Reforma, you might make a stop by sights like Plaza Mazari and Plaza Parque.

San Agustín Yatareni

San Agustín Yatareni might not have many top sights, but El Llano Park and Oaxaca Ethnobotanical Garden are two attractions nearby that you can check out.

Top Santa María Hotel Reviews

Casa Mayahuel

Casa Mayahuel

10/10 Excellent
"El lugar, perfecto para un par de días, cerca de tiendas muy cerca del centro del Zócalo, lugares hermosos para visitar"
Laura 5-night trip
Posted 5 days ago
Casa Mayahuel
HOTEL POSADA DON MATIAS

HOTEL POSADA DON MATIAS

10/10 Excellent
"Staff is extremely friendly and helpful to our family. "
Laura 2-night trip
Posted 2 weeks ago
HOTEL POSADA DON MATIAS

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Frequently asked questions

What is Santa María like?
Travellers to the Santa María neighbourhood in Oaxaca will be sure to enjoy their stay.
If I need to cancel my hotel reservation in Santa María, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to review the best options available in Santa María.
What is there to do in this Oaxaca neighbourhood?
Cerro del Fortín, Parque Juarez El Llano and Auditorio Guelaguetza are just a few of the places to visit in and around Santa María. While you're out sightseeing in Oaxaca, make sure that you visit other sights such as Ex-Convento de Santa Catalina or El Mirador.