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17 Aug - 18 Aug
Tomorrow
18 Aug - 19 Aug
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21 Aug - 23 Aug
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28 Aug - 30 Aug

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Our top choices for St. Charles hotels

Inn
Budget
Hotel
Reserve now, pay later
Breakfast included
Reception
In-room safe, laptop workspace, blackout curtains, iron/ironing board
Lobby
Restaurant

1. Hampton Inn Rochester-South

Hampton Inn Rochester-South
Rochester
United States
Lynne
Rp1.666.468
Rp1.918.521 total
includes taxes & fees
28 Aug - 29 Aug
Hampton Inn Rochester-South
Desk, blackout curtains, iron/ironing board, free cots/infant beds
Fitness facility
Standard Room, 1 King Bed, Non Smoking | Desk, blackout curtains, iron/ironing board, free cots/infant beds
Indoor pool, open 7:00 AM to 11:00 PM, pool loungers

2. Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic
Rochester
United States
Anne
Rp1.373.392
Rp1.581.117 total
includes taxes & fees
30 Aug - 31 Aug
Comfort Inn & Suites Rochester South Mayo Clinic
Exterior
Exterior
Restaurant
Suite, 1 King Bed, Jetted Tub | In-room safe, desk, laptop workspace, iron/ironing board

3. Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
Rochester
United States
Stephanie
Rp1.657.911
Rp1.908.671 total
includes taxes & fees
23 Aug - 24 Aug
Holiday Inn Express Rochester South - Mayo Area by IHG
Lunch and dinner served
Bar (on property)
Reception
Terrace/patio

4. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Historic Southwest
United States
Brandolyn
Rp2.035.839
Rp2.343.758 total
includes taxes & fees
21 Aug - 22 Aug
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Front of property
Restaurant
Lobby sitting area
Lobby

5. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Rochester
United States
Darrel
Rp1.348.613
Rp1.552.591 total
includes taxes & fees
23 Aug - 24 Aug
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
2 indoor pools
Lobby sitting area
Free daily continental breakfast
Fitness facility

6. Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area
Kutzky Park
United States
Olivia
Rp1.347.721
Rp1.551.563 total
includes taxes & fees
18 Aug - 19 Aug
Med City Inn & Suites - Mayo Clinic Area
Terrace/patio
Exterior
Indoor pool, open 7:00 AM to 10:00 PM, pool loungers
Lobby

7. Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
Downtown Rochester
United States
Melissa
Rp2.834.493
Rp3.263.211 total
includes taxes & fees
20 Aug - 21 Aug
Hyatt House Rochester/Mayo Clinic Area
Serves lunch, dinner and happy hour
Apartment, 1 Bedroom, 2 Queen Beds, Non Smoking | Premium bedding, down duvets, pillow-top beds, desk
Lunch and dinner served
Apartment, 1 King Bed, Accessible, Non Smoking (Mobility/Hearing, Tub w/Grab bars) | Premium bedding, down duvets, pillow-top beds, desk

8. AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
Rochester
United States
Luis
Rp1.344.869
Rp1.548.281 total
includes taxes & fees
23 Aug - 24 Aug
AmericInn by Wyndham Rochester Near Mayo Clinic
Indoor pool, open 7:00 AM to 10:00 PM, pool loungers
Suite, 2 Double Beds, Poolside | Desk, blackout curtains, iron/ironing board, free cots/infant beds
Exterior
Restaurant

9. Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area
Downtown Rochester
United States
Hafsa
Rp2.230.158
Rp2.567.623 total
includes taxes & fees
18 Aug - 19 Aug
Kahler Inn and Suites - Mayo Clinic Area
Indoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, pool loungers
Standard Room, 2 Queen Beds, Accessible, Refrigerator & Microwave | Blackout curtains, soundproofing, iron/ironing board, rollaway beds
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room) | Blackout curtains, soundproofing, iron/ironing board, rollaway beds
Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Living Room) | Blackout curtains, soundproofing, iron/ironing board, rollaway beds

10. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Rochester
United States
Margita
Rp1.676.629
Rp1.930.219 total
includes taxes & fees
23 Aug - 24 Aug
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Studio Suite, 1 King Bed, Non Smoking | Desk, blackout curtains, iron/ironing board, free cots/infant beds
Lobby
Exterior
Suite, 1 King Bed, Non Smoking | Desk, blackout curtains, iron/ironing board, free cots/infant beds

11. AmericInn by Wyndham Winona

AmericInn by Wyndham Winona
Winona
United States
Jacob
Rp2.106.260
Rp2.351.114 total
includes taxes & fees
13 Sept - 14 Sept
AmericInn by Wyndham Winona
Reception
Snack bar
Studio, 1 Queen Bed | Living area | 40-inch flat-screen TV with digital channels, TV
Exterior

12. Spark by Hilton Rochester South

Spark by Hilton Rochester South
Rochester
United States
Susanne
Rp1.447.196
Rp1.666.085 total
includes taxes & fees
23 Aug - 24 Aug
Spark by Hilton Rochester South
Exterior
Exterior
Room amenity
Indoor pool

13. Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Kutzky Park
United States
Janet
Rp1.693.565
Rp1.949.716 total
includes taxes & fees
22 Aug - 23 Aug
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Lobby sitting area
Courtyard
Reception
Desk, iron/ironing board (on request), free WiFi, bed sheets

14. Brentwood Inn & Suites

Brentwood Inn & Suites
Downtown Rochester
United States
Bryan
Rp2.228.375
Rp2.565.484 total
includes taxes & fees
18 Aug - 19 Aug
Brentwood Inn & Suites
Indoor pool
Premium bedding, desk, laptop workspace, blackout curtains
2 restaurants; breakfast, lunch and dinner served
Ballroom

15. Kahler Grand Hotel

Kahler Grand Hotel
Downtown Rochester
United States
Kevin
Rp2.390.601
Rp2.752.311 total
includes taxes & fees
20 Aug - 21 Aug
Kahler Grand Hotel
Terrace/patio
Lobby
Free daily buffet breakfast
Egyptian cotton sheets, premium bedding, pillow-top beds, minibar

16. Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
Rochester
United States
Timothy
Rp2.040.300
Rp2.348.896 total
includes taxes & fees
27 Aug - 28 Aug
Home2 Suites by Hilton Rochester Mayo Clinic Area
Iron/ironing board (on request), free cots/infant beds, free WiFi
Free daily continental breakfast
Iron/ironing board (on request), free cots/infant beds, free WiFi
Indoor pool

17. Baymont by Wyndham Rochester Mayo Clinic Area

Baymont by Wyndham Rochester Mayo Clinic Area
Rochester
United States
Denise
Rp1.060.885
Rp1.221.344 total
includes taxes & fees
30 Aug - 31 Aug
Baymont by Wyndham Rochester Mayo Clinic Area
Exterior
Terrace/patio
Exterior
Breakfast, lunch and dinner served

18. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
Downtown Rochester
United States
Misty
Rp1.836.181
Rp2.113.904 total
includes taxes & fees
21 Aug - 22 Aug
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Free daily full breakfast
Standard Room, 1 King Bed, Non Smoking | Desk, free WiFi, bed sheets
Laundry room
Lobby sitting area

19. Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
Rochester
United States
Markus
Rp1.248.603
Rp1.437.454 total
includes taxes & fees
13 Sept - 14 Sept
Econo Lodge Mayo Clinic Area
Restaurant
Exterior
Two queens bed non smoking | Premium bedding, in-room safe, laptop workspace, blackout curtains
Indoor pool, open 6 AM to midnight, pool loungers

20. Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
Rochester
United States
Albert
Rp1.739.559
Rp2.002.667 total
includes taxes & fees
30 Aug - 31 Aug
Hampton Inn & Suites Rochester-North
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Learn more about St. Charles

St. Charles awaits: its natural setting and more!

See all hotels in St. Charles
An aerial view of a town with industrial buildings, roads, and green areas.

Top St. Charles Hotel Reviews

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

8/10 Good
"Clean, nice breakfast"
Nancy 2-night trip
Posted 8 hours ago
AmericInn by Wyndham Rochester Near Mayo Clinic
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

10/10 Excellent
"Nice hotel in a great location. They had patio dining. We didn’t get a chance to eat there but would like to the next time we’re in the area. Customer service was excellent! I had an early flight which they accommodated and let me check in early and I was able to take a long nap. Hotel could use a renovation but then rates would be a lot higher. The room was clean and that was what counted the most. The air freshener on the 2nd floor was a little strong for my liking. They had a nice selection for breakfast which was complimentary. The breakfast area was spacious with plenty of room to eat. I would stay here again. Thank you!"
Sandra 2-night trip
Posted 11 hours ago
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

8/10 Good
"We loved the pool."
Abigail 3-night trip
Posted 11 hours ago
Med City Inn & Suites - Mayo Clinic Area
Super 8 by Wyndham Winona MN

Super 8 by Wyndham Winona MN

10/10 Excellent
"Great location and view over the town/river."
Noel 1-night trip
Posted 11 hours ago
Super 8 by Wyndham Winona MN
Kahler Grand Hotel

Kahler Grand Hotel

10/10 Excellent
"Clean room, location is perfect for visits to Mayo Clinic."
James 1-night trip
Posted 12 hours ago
Kahler Grand Hotel
Super 8 by Wyndham Rochester Mayo Clinic Area

Super 8 by Wyndham Rochester Mayo Clinic Area

10/10 Excellent
"It was a convenient stop on my trip."
Madison 1-night trip
Posted 13 hours ago
Super 8 by Wyndham Rochester Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent
"Easy access yo Mayo Clinic. Right across the street. This is a no frills just hotel spot."
CYNTHIA 4-night trip
Posted 13 hours ago
Kahler Inn and Suites - Mayo Clinic Area
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

10/10 Excellent
"Great hotel and the coffee station and free meals were a pleasant surprise !"
Patricia 7-night trip
Posted 21 hours ago
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Hampton Inn Rochester-South

Hampton Inn Rochester-South

10/10 Excellent
"Everything functioned as it should."
William 1-night trip
Posted 2 days ago
Hampton Inn Rochester-South

More cheap stays in St. Charles

Super 8 by Wyndham Rochester Mayo Clinic Area

Super 8 by Wyndham Rochester Mayo Clinic Area

106 SE 21st Street Rochester MN
Rp924.330
Rp1.064.134 total
30 Aug - 31 Aug
includes taxes & fees
7.8/10 Good! (1,007 reviews)
Super 8 by Wyndham Rochester Mayo Clinic Area
Super 8 by Wyndham Winona MN

Super 8 by Wyndham Winona MN

1025 Sugar Loaf Rd Winona MN
Rp1.105.274
Rp1.255.867 total
13 Sept - 14 Sept
includes taxes & fees
7.6/10 Good! (1,019 reviews)
Super 8 by Wyndham Winona MN
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN
Rp1.347.721
Rp1.551.563 total
18 Aug - 19 Aug
includes taxes & fees
Med City Inn & Suites - Mayo Clinic Area
Hampton Inn Rochester-South

Hampton Inn Rochester-South

1755 S Broadway Rochester MN
Rp1.666.468
Rp1.918.521 total
28 Aug - 29 Aug
includes taxes & fees
9/10 Wonderful! (1,004 reviews)
Hampton Inn Rochester-South
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

1517 16th St Sw Rochester MN
Rp1.676.629
Rp1.930.219 total
23 Aug - 24 Aug
includes taxes & fees
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Brentwood Inn & Suites

Brentwood Inn & Suites

123 Fourth Ave. NW Rochester MN
Rp2.228.375
Rp2.565.484 total
18 Aug - 19 Aug
includes taxes & fees
8.8/10 Excellent! (1,006 reviews)
Brentwood Inn & Suites

Frequently asked questions

Where is the best place to stay in St. Charles?
Kahler Grand Hotel, located 20.6 mi (33.1 km) from the heart of St. Charles, is a top choice for your stay, based on our traveller data. Two other options for your stay in the area are Med City Inn & Suites - Mayo Clinic Area and Kahler Inn and Suites - Mayo Clinic Area. See all available top hotels, or vacation rentals in St. Charles.
If I need to cancel my hotel reservation in St. Charles, will I receive a refund?
Yes! The majority of room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in St. Charles.
What's it like to stay in St. Charles?
Visitors can enjoy all that St. Charles has to offer, including its parks. This city also attracts tourists with its welcoming locals. In St. Charles, there are 3 hotels and other accommodation options to choose from. Find out more about St. Charles.
What is there to see in St. Charles?
A couple of favourite places to visit are Whitewater State Park and Whitewater River. You'll also find Regional Sports Center and National Volleyball Center in the area. Take a look at what more there is to see and do in Expedia's St. Charles guide.
What's the weather like in St. Charles?
The hottest months are usually July and August, with an average temperature of 19°C, while the coldest months are January and February, with an average of -6°C. The snowiest months in St. Charles are January, March, February and April, with each month seeing an average of 20 cm of snowfall.

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