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Check prices for these dates

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30 Oct - 1 Nov
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6 Nov - 8 Nov

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Our top choices for Substance hotels

A rooftop lounge with a fire pit, large windows, and a city view.

1. Circa Resort & Casino – Adults Only

Circa Resort & Casino – Adults Only
4.5 star property
Downtown Las Vegas, 0.5 km from Substance
9.4 out of 10, Exceptional, (5,750 reviews)
"Great place to stay"
United States
Cesar
The price is Rp2.158.303
Rp3.463.623 total
includes taxes & fees
2 Nov - 3 Nov
Circa Resort & Casino – Adults Only
A storefront with a glass door, a black awning, and a floral archway.

2. The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over

The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over
4.0 star property
Arts District, 1.4 km from Substance
9.2 out of 10, Wonderful, (158 reviews)
"Great stay"
United States
Enrico
The price is Rp2.920.057
Rp3.299.664 total
includes taxes & fees
22 Nov - 23 Nov
The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over
A bar area with multiple stools and tables, a well-stocked bar counter, and framed signs on the wall.

3. Fremont Hotel & Casino

Fremont Hotel & Casino
3.0 star property
Downtown Las Vegas, 0.3 km from Substance
8.8 out of 10, Excellent, (4,659 reviews)
"Will definitely stay here again 🤗"
United States
Dianne
The price is Rp666.488
Rp1.449.774 total
includes taxes & fees
16 Nov - 17 Nov
Fremont Hotel & Casino
A bar area with a leather couch, red chairs, and a bar counter.

4. Downtown Grand Las Vegas

Downtown Grand Las Vegas
3.5 star property
Downtown Las Vegas, 0.2 km from Substance
8.6 out of 10, Excellent, (9,939 reviews)
"Great place"
United States
Chase
The price is Rp755.406
Rp1.652.908 total
includes taxes & fees
22 Nov - 23 Nov
Downtown Grand Las Vegas
A hotel room with a large bed, a desk, a chair, a lamp, and a window with curtains.

5. Four Queens Hotel and Casino

Four Queens Hotel and Casino
3.5 star property
Downtown Las Vegas, 0.3 km from Substance
8.6 out of 10, Excellent, (7,443 reviews)
"Always a nice place to stay"
United States
jose
The price is Rp1.251.421
Rp1.414.106 total
includes taxes & fees
9 Nov - 10 Nov
Four Queens Hotel and Casino
A brick-walled interior with a wooden floor and a black metal railing.

6. the D Las Vegas

the D Las Vegas
3.5 star property
Downtown Las Vegas, 0.2 km from Substance
8.6 out of 10, Excellent, (7,724 reviews)
"Nice place to stay."
United States
Dave
The price is Rp525.973
Rp1.413.053 total
includes taxes & fees
9 Nov - 10 Nov
the D Las Vegas
A bedroom with a bed, a small table, and a chair. There is a bathroom with a sink, mirror, and shower.

7. Desert Moon Motel

Desert Moon Motel
2.5 star property
Downtown Las Vegas, 1.5 km from Substance
8.4 out of 10, Very good, (522 reviews)
"A great value for an extremely nice and clean hotel room. Great staff and location too !"
United States
Grant
The price is Rp899.365
Rp1.016.282 total
includes taxes & fees
1 Dec - 2 Dec
Desert Moon Motel
A restaurant with a view of a neon-lit building and a large screen displaying an image of a person.

8. Hotel Apache

Hotel Apache
3.5 star property
Downtown Las Vegas, 0.4 km from Substance
8.4 out of 10, Very good, (1,167 reviews)
"Always a nice place to stay"
United States
jose
The price is Rp889.294
Rp1.004.902 total
includes taxes & fees
1 Dec - 2 Dec
Hotel Apache
A large, modern steakhouse with a curved roof and multiple dining areas, surrounded by other buildings.

9. Plaza Hotel & Casino

Plaza Hotel & Casino
4.0 star property
Downtown Las Vegas, 0.6 km from Substance
8.4 out of 10, Very good, (5,699 reviews)
"The location is great free parking and breakfast options"
United States
saul
The price is Rp636.609
Rp1.518.792 total
includes taxes & fees
22 Nov - 23 Nov
Plaza Hotel & Casino
A hotel with a large indoor pool, palm trees, and a modern building in the background.

10. Golden Nugget Las Vegas Hotel & Casino

Golden Nugget Las Vegas Hotel & Casino
4.0 star property
Downtown Las Vegas, 0.4 km from Substance
8.2 out of 10, Very good, (14,786 reviews)
"Wonderful stay, clean rooms, comfy beds, large bathrooms, and lovely restaurants!"
United States
Andrea
The price is Rp642.050
Rp1.668.278 total
includes taxes & fees
1 Nov - 2 Nov
Golden Nugget Las Vegas Hotel & Casino
A hotel room with two beds, a desk, a chair, a large mirror, and a decorative wall with geometric patterns.

11. Downtowner Boutique Hotel

Downtowner Boutique Hotel
3.0 star property
Downtown Las Vegas, 0.4 km from Substance
8.0 out of 10, Very good, (183 reviews)
"Cute clean hotel, located just off the hustle and bustle of Fremont street."
United States
Nicholas
The price is Rp636.609
Rp1.129.264 total
includes taxes & fees
8 Nov - 9 Nov
Downtowner Boutique Hotel
A nighttime view of a pool area with a city skyline in the background, including a prominent tower.

12. Bposhtels Las Vegas

Bposhtels Las Vegas
2.5 star property
1.8 km from Substance
7.8 out of 10, Good, (351 reviews)
"The manager was very kind The house keeping was great and polite I. Would love to stay again but now have a local id Thanks Nichole"
United States
Nichole
The price is Rp417.151
Rp676.328 total
includes taxes & fees
1 Nov - 2 Nov
Bposhtels Las Vegas
A hotel with a prominent sign reading "California Hotel & Casino."

13. California Hotel and Casino

California Hotel and Casino
3.5 star property
Downtown Las Vegas, 0.5 km from Substance
8.8 out of 10, Excellent, (1,471 reviews)
"Love the location and the food was great."
United States
Norman Paul Cruz
The price is Rp577.664
Rp1.328.907 total
includes taxes & fees
16 Nov - 17 Nov
California Hotel and Casino
A hotel with a prominent tower and the name "STRAT" illuminated on the facade.

14. The STRAT Hotel, Casino & Tower

The STRAT Hotel, Casino & Tower
4.0 star property
Las Vegas Strip, 2.9 km from Substance
7.8 out of 10, Good, (25,893 reviews)
"I love staying here when I visit!"
United States
Steve
The price is Rp244.849
Rp1.304.708 total
includes taxes & fees
9 Nov - 10 Nov
The STRAT Hotel, Casino & Tower
A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and tall buildings.

15. Oasis at Gold Spike

Oasis at Gold Spike
3.5 star property
Downtown Las Vegas, < 0.1 km from Substance
8.2 out of 10, Very good, (2,342 reviews)
"Great hotel"
United States
Zachary
The price is Rp799.842
Rp1.416.191 total
includes taxes & fees
1 Nov - 2 Nov
Oasis at Gold Spike
The exterior of the Golden Gate Hotel with a prominent sign, a modern architectural design, and a parking lot with visible cars.

16. Golden Gate Hotel and Casino

Golden Gate Hotel and Casino
2.5 star property
Downtown Las Vegas, 0.5 km from Substance
7.6 out of 10, Good, (1,162 reviews)
"Great place to stay"
United States
Christian
The price is Rp435.288
Rp1.310.579 total
includes taxes & fees
9 Nov - 10 Nov
Golden Gate Hotel and Casino
A neon sign for a hotel with a large '8' and the word 'HOTEL' in bold letters.

17. Super 8 by Wyndham Las Vegas North Strip/Fremont St. Area

Super 8 by Wyndham Las Vegas North Strip/Fremont St. Area
2.0 star property
1.7 km from Substance
7.0 out of 10, Good, (1,002 reviews)
"Absolutely amazing love staying here"
United States
Colleen
The price is Rp585.825
Rp866.930 total
includes taxes & fees
22 Nov - 23 Nov
Super 8 by Wyndham Las Vegas North Strip/Fremont St. Area
An outdoor seating area with wicker furniture, palm trees, and a clear sky.

18. Thunderbird Hotel

Thunderbird Hotel
2.5 star property
Gateway District, 1.8 km from Substance
7.2 out of 10, Good, (1,003 reviews)
"Great location clean room and bedding"
United States
Edgar
The price is Rp799.842
Rp1.252.178 total
includes taxes & fees
1 Nov - 2 Nov
Thunderbird Hotel
A hotel room with a large bed, a bedside table, a chair, a desk, and a mirror.

19. Crown Motel

Crown Motel
2.5 star property
Sunrise Manor, 3.1 km from Substance
7.4 out of 10, Good, (80 reviews)
"Decent hotel"
United States
Jeff
The price is Rp2.432.172
Rp2.929.725 total
includes taxes & fees
1 Nov - 2 Nov
Crown Motel
A hotel room with two beds, a desk, a chair, a TV, and a minibar.

20. Motel 6 Las Vegas, Nv – Downtown Fremont St

Motel 6 Las Vegas, Nv – Downtown Fremont St
2.0 star property
2.6 km from Substance
6.6 out of 10, (317 reviews)
"The office was pleasant and cancelled the reservation immediately. The neighborhood was scary. We were uncomfortable parking and leaving new car overnite. Have stayed in numerous Motel 6s and enjoyed them all. This location is not comfortable. Not the old Vegas we knew. Sorry..."
United States
Kaye
The price is Rp1.432.460
Rp1.618.546 total
includes taxes & fees
1 Nov - 2 Nov
Motel 6 Las Vegas, Nv – Downtown Fremont St
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels near Substance

A rooftop lounge with a fire pit, large windows, and a city view.

Circa Resort & Casino – Adults Only

4.5 star property
Downtown Las Vegas, 0.5 km from Substance
View
A storefront with a glass door, a black awning, and a floral archway.

The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over

4.0 star property
Arts District, 1.4 km from Substance
View
A bar area with multiple stools and tables, a well-stocked bar counter, and framed signs on the wall.

Fremont Hotel & Casino

3.0 star property
Downtown Las Vegas, 0.3 km from Substance
View
A bar area with a leather couch, red chairs, and a bar counter.

Downtown Grand Las Vegas

3.5 star property
Downtown Las Vegas, 0.2 km from Substance
View
A hotel room with a large bed, a desk, a chair, a lamp, and a window with curtains.

Four Queens Hotel and Casino

3.5 star property
Downtown Las Vegas, 0.3 km from Substance
View
9.4
Exceptional
5,750 reviews
9.2
Wonderful
158 reviews
8.8
Excellent
4,659 reviews
8.6
Excellent
9,939 reviews
8.6
Excellent
7,443 reviews
The price is Rp2.158.303
Rp3.463.623 total
includes taxes & fees
2 Nov - 3 Nov
The price is Rp2.920.057
Rp3.299.664 total
includes taxes & fees
22 Nov - 23 Nov
The price is Rp666.488
Rp1.449.774 total
includes taxes & fees
16 Nov - 17 Nov
The price is Rp755.406
Rp1.652.908 total
includes taxes & fees
22 Nov - 23 Nov
The price is Rp1.251.421
Rp1.414.106 total
includes taxes & fees
9 Nov - 10 Nov
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • No Pool
  • No Spa
  • No Pet-friendly
  • No WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking

Hotels recommended for families near Substance

A hotel room with a large bed, a desk, a chair, a lamp, and a window with curtains.

Four Queens Hotel and Casino

Four Queens Hotel and Casino
3.5 star property
Downtown Las Vegas
8.6 out of 10, Excellent, (7,443)
The price is Rp1.251.421
Rp1.414.106 total
includes taxes & fees
9 Nov - 10 Nov
Four Queens Hotel and Casino

Top Substance Hotel Reviews

Fremont Hotel & Casino

Fremont Hotel & Casino

10/10 Excellent
"As always our stay and customer service is always consistent that’s why we never stay anywhere else."
Mylene 2-night trip
Posted less than an hour ago
Fremont Hotel & Casino

Other attractions near Substance

The exterior of the Neonopolis building with the Telemundo Las Vegas sign above.

Neonopolis

You can spend time exploring the galleries in Neonopolis in Las Vegas. Discover the entertainment choices and casinos in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Substance?
Substance is located in Las Vegas. This welcoming area is known for its array of dining options and bar scene. If you're looking for a convenient place to stay, take a look at the 156 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near Substance?
Adjacent to Substance, Golden Nugget Las Vegas Hotel & Casino is one of the top choices for your stay based on our traveller data, and this resort offers 2 outdoor pools and a full-service spa. Other good options within a short distance include Plaza Hotel & Casino and Downtown Grand Las Vegas.
How many hotels will I be able to find close to Substance?
Expedia has 156 hotels and other accommodation options within a mile from Substance.
If I need to cancel the hotel reservation for my stay near Substance, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to view the top deals on offer near Substance.
What can I see and do near Substance?
You might want to spend some time browsing the exhibits at Mob Museum, The Neon Museum or Zak Bagans Haunted Museum. Old Las Vegas Mormon Fort State Historic Park, Harrison House and First AME Church are monuments to see when you're exploring the area around Substance. You can watch performances at Colosseum at Caesars Palace, Sphere and Dolby Live if you're interested in local theatre.