Uptown Greenville Holidays
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Save up to Rp173.195 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Where to stay in Uptown Greenville
Find the best Uptown Greenville areas and neighborhoods for the activities you enjoy most. Learn more about Uptown Greenville
Medical District
2 out of top 10 points of interest in this area
If you're looking for some top things to see and do in Medical District and surrounding area, you can visit Arlington Crossing and Town Common.
Top hotels in Uptown Greenville
Hilton Garden INN Greenville University
423 EVANS ST, Greenville, NC
Fully refundableReserve now, pay when you stay
The price is Rp2.064.395 per night from 20 Jul to 21 Jul
Rp2.064.395
Rp2.332.766 total
20 Jul - 21 Jul
includes taxes & fees
9.2/10 Wonderful! (32 reviews)
"Awesome"
Reviewed on 23 Jun 2025
Microtel Inn & Suites by Wyndham Greenville/University Medic
450 Moye Blvd, Greenville, NC
Fully refundableReserve now, pay when you stay
The price is Rp1.163.820 per night from 29 Jun to 30 Jun
Rp1.163.820
Rp1.315.117 total
29 Jun - 30 Jun
includes taxes & fees
7/10 Good! (1,000 reviews)
"Clean, convenient"
Reviewed on 22 Jun 2025
Baymont by Wyndham Greenville
3439 S Memorial Drive, Greenville, NC
Fully refundableReserve now, pay when you stay
The price is Rp1.163.820 per night from 21 Jul to 22 Jul
Rp1.163.820
Rp1.315.117 total
21 Jul - 22 Jul
includes taxes & fees
6.4/10 (1,001 reviews)
"Nice"
Reviewed on 25 Jun 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Vidant Medical Center
If Vidant Medical Center is what brings you to town, hopefully you'll have a chance to explore more of Greenville.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.