Medical Center District Hotel Guide - 4 Stars Hotels in Medical Center District, San Antonio

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Our top choices for Medical Center District 4-star hotels

Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk
4.0 star property
Downtown San Antonio
9.4 out of 10, Exceptional, (4,610 reviews)
"Very friendly staff, breakfast is great and the location is wonderful, we really enjoyed our time there."
United States
alberto
The price is Rp2.607.126
Rp3.081.858 total
includes taxes & fees
7 Jun - 8 Jun
Drury Plaza Hotel San Antonio Riverwalk

Riverwalk Plaza

Riverwalk Plaza
4.0 star property
Downtown San Antonio
8.0 out of 10, Very good, (6,464 reviews)
"Great stay overall… convenient and comfortable."
United States
Ray
The price is Rp1.548.736
Rp1.830.746 total
includes taxes & fees
11 May - 12 May
Riverwalk Plaza

Hotel Contessa

Hotel Contessa
4.0 star property
Downtown San Antonio
9.0 out of 10, Wonderful, (3,564 reviews)
"Great Stay, easy the hot spots downtown and right on the riverwalk."
United States
Abram
The price is Rp3.558.964
Rp4.732.823 total
includes taxes & fees
13 May - 14 May
Hotel Contessa

Kimpton Santo San Antonio - Riverwalk by IHG

Kimpton Santo San Antonio - Riverwalk by IHG
4.5 star property
Downtown San Antonio
9.4 out of 10, Exceptional, (908 reviews)
"Great stay! Super clean, wonderful staff!"
United States
Robert
The price is Rp2.937.558
Rp3.922.596 total
includes taxes & fees
17 May - 18 May
Kimpton Santo San Antonio - Riverwalk by IHG

Hyatt Regency Hill Country Resort and Villas

Hyatt Regency Hill Country Resort and Villas
4.0 star property
Far West Side
8.8 out of 10, Excellent, (1,004 reviews)
"It was a beautiful place, cant wait to go back "
United States
Melissa
The price is Rp5.895.105
Rp8.329.856 total
includes taxes & fees
17 May - 18 May
Hyatt Regency Hill Country Resort and Villas

Hotel Valencia Riverwalk

Hotel Valencia Riverwalk
4.5 star property
Downtown San Antonio
9.4 out of 10, Exceptional, (2,720 reviews)
"Excellent hotel, excellent breakfast choices and very clean."
United States
Sherri
The price is Rp2.228.288
Rp3.130.640 total
includes taxes & fees
4 Jun - 5 Jun
Hotel Valencia Riverwalk

Omni La Mansion del Rio

Omni La Mansion del Rio
4.0 star property
Downtown San Antonio
9.4 out of 10, Exceptional, (2,931 reviews)
"Good stay, great location."
United States
Tammy
The price is Rp3.633.012
Rp4.358.965 total
includes taxes & fees
1 Jun - 2 Jun
Omni La Mansion del Rio

Hilton Palacio Del Rio

Hilton Palacio Del Rio
4.0 star property
Downtown San Antonio
9.0 out of 10, Wonderful, (1,176 reviews)
"Enjoyed the stay "
United States
HOMA
The price is Rp3.235.659
Rp3.824.841 total
includes taxes & fees
17 May - 18 May
Hilton Palacio Del Rio

Hyatt Regency San Antonio Riverwalk

Hyatt Regency San Antonio Riverwalk
4.0 star property
Downtown San Antonio
9.2 out of 10, Wonderful, (2,142 reviews)
"Beautiful stay. "
United States
Cassandra
The price is Rp3.285.198
Rp4.442.927 total
includes taxes & fees
30 May - 31 May
Hyatt Regency San Antonio Riverwalk

The Westin Riverwalk, San Antonio

The Westin Riverwalk, San Antonio
4.0 star property
Downtown San Antonio
8.8 out of 10, Excellent, (1,535 reviews)
"Beautiful hotel"
United States
CHRISTINA
The price is Rp3.087.912
Rp3.677.480 total
includes taxes & fees
31 May - 1 Jun
The Westin Riverwalk, San Antonio

JW Marriott San Antonio Hill Country Resort & Spa

JW Marriott San Antonio Hill Country Resort & Spa
4.5 star property
San Antonio
9.0 out of 10, Wonderful, (1,007 reviews)
"Very family friendly!"
United States
Craig
The price is Rp6.587.778
Rp8.977.803 total
includes taxes & fees
26 May - 27 May
JW Marriott San Antonio Hill Country Resort & Spa

Signia by Hilton La Cantera Resort & Spa

Signia by Hilton La Cantera Resort & Spa
4.0 star property
La Cantera District
9.0 out of 10, Wonderful, (1,043 reviews)
"Clean room and friendly staff. Everyone on the property always has a big smile!"
United States
Richie
The price is Rp4.905.200
Rp6.911.705 total
includes taxes & fees
27 May - 28 May
Signia by Hilton La Cantera Resort & Spa

Grand Hyatt San Antonio River Walk

Grand Hyatt San Antonio River Walk
4.0 star property
Downtown San Antonio
9.2 out of 10, Wonderful, (1,378 reviews)
"Loved my room and enjoyed my stay"
United States
Esmeralda
The price is Rp3.215.670
Rp4.463.465 total
includes taxes & fees
31 May - 1 Jun
Grand Hyatt San Antonio River Walk

InterContinental San Antonio Riverwalk by IHG

InterContinental San Antonio Riverwalk by IHG
4.5 star property
Downtown San Antonio
9.2 out of 10, Wonderful, (681 reviews)
"Great place to stay."
United States
Edward
The price is Rp2.937.558
Rp4.193.637 total
includes taxes & fees
31 May - 1 Jun
InterContinental San Antonio Riverwalk by IHG

Canopy by Hilton San Antonio Riverwalk

Canopy by Hilton San Antonio Riverwalk
4.0 star property
Downtown San Antonio
9.4 out of 10, Exceptional, (1,680 reviews)
"Nice place to stay"
United States
Ivan
The price is Rp2.585.572
Rp3.525.692 total
includes taxes & fees
1 Jun - 2 Jun
Canopy by Hilton San Antonio Riverwalk

Plaza San Antonio Hotel & Spa, Autograph Collection

Plaza San Antonio Hotel & Spa, Autograph Collection
4.0 star property
Downtown San Antonio
9.4 out of 10, Exceptional, (799 reviews)
"Beautiful hotel, valet is pricey around $70.00 per night, but other than that we had a great stay. Lots to do in the area and staff was very friendly."
United States
brandee
The price is Rp2.112.782
Rp3.035.220 total
includes taxes & fees
17 May - 18 May
Plaza San Antonio Hotel & Spa, Autograph Collection

The Westin San Antonio North

The Westin San Antonio North
4.0 star property
Vance Jackson
8.6 out of 10, Excellent, (1,372 reviews)
"A wonderful and beautiful place to stay "
United States
Uriel
The price is Rp1.755.582
Rp2.103.762 total
includes taxes & fees
17 May - 18 May
The Westin San Antonio North

Mokara Hotel & Spa San Antonio

Mokara Hotel & Spa San Antonio
4.5 star property
Downtown San Antonio
9.6 out of 10, Exceptional, (1,003 reviews)
"Beautiful Property"
United States
John Paul
The price is Rp5.371.212
Rp6.364.953 total
includes taxes & fees
11 May - 12 May
Mokara Hotel & Spa San Antonio

Hilton San Antonio Hill Country

Hilton San Antonio Hill Country
4.0 star property
Far West Side
8.6 out of 10, Excellent, (1,106 reviews)
"nice hotel"
United States
Zeeshan
The price is Rp2.040.647
Rp3.098.469 total
includes taxes & fees
31 May - 1 Jun
Hilton San Antonio Hill Country

Aiden San Antonio Riverwalk

Aiden San Antonio Riverwalk
4.0 star property
Downtown San Antonio
9.2 out of 10, Wonderful, (1,267 reviews)
"The staff was very friendly and helpful. Definitely going to stay there in the future."
United States
Miriam
The price is Rp1.786.001
Rp2.085.157 total
includes taxes & fees
25 May - 26 May
Aiden San Antonio Riverwalk
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Top Medical Center District Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Medical Centre District?
When you plan your visit to The Westin San Antonio North, you can count on excellent service, comfortable bedding and plenty of handy amenities. This 4-star hotel located conveniently around Medical Centre District consistently receives top marks from our guests.
How much does it cost to stay in a 4-star hotel in Medical Centre District?
Expedia can help you quickly track down the ideal 4-star hotel for your holiday in Medical Centre District. Use our handy filter tool to tailor your search by things like budget, amenities and star rating and get access to awesome deals in a few clicks.

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What's the difference between 5-star and 4-star hotels in Medical Centre District?
Offering a friendly traveller experience and upmarket surroundings, 4-star hotels are an excellent option for your Medical Centre District break. These types of stays generally feature lots of handy amenities that make it easy to unpack and unwind — think large beds, bathrobes, pools and restaurants. Or live the high life at a 5-star hotel designed to spoil you with luxury perks and amenities. On-site health clubs, complimentary toiletries and gourmet dining are typically included at these deluxe properties.