Cape Girardeau County Holidays

Book a Hotel + Flight or Car together to unlock savings

Photo by Skyy

  • Plan, book, travel with confidence

    • Better together

    Save up to Rp173.195 when you book a flight and hotel together*

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

    Rest easy

    Plan, book, and manage your trip all in one place

Top hotels in Cape Girardeau County

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is Rp1.491.134 per night from 19 Oct to 20 Oct
Rp1.491.134
Rp1.682.021 total
19 Oct - 20 Oct
includes taxes & fees
9.4/10 Exceptional! (1,015 reviews)
"Great staff"

Reviewed on 12 Oct 2025

Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

2 out of 5
777 Main St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is Rp1.893.951 per night from 19 Oct to 20 Oct
Rp1.893.951
Rp2.136.642 total
19 Oct - 20 Oct
includes taxes & fees
9.2/10 Wonderful! (433 reviews)
"Newer hotel so clean. Walk-in shower with no door but works. Control is on opposite side of shower head so alittle awkward. Starbucks was nice. Front desk very accommodating. Close to old downtown but too far to walk. Railroad tracks on east side but didn’t reallly hear."

Reviewed on 7 Oct 2025

The Riverview
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
Fully refundableReserve now, pay when you stay
The price is Rp1.394.366 per night from 15 Oct to 16 Oct
Rp1.394.366
Rp1.509.052 total
15 Oct - 16 Oct
includes taxes & fees
8.8/10 Excellent! (634 reviews)
"Clean"

Reviewed on 8 Oct 2025

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
See all 239 properties in Cape Girardeau County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Cape Girardeau County holiday package cost?
Perhaps less than you imagined — from a tempting , actually! By bundling hotels, flights and car rentals into your own customized travel package, your trip to Cape Girardeau County is just a few clicks away.
How do I get a cheap travel package to Cape Girardeau County?
Creating your own Cape Girardeau County holiday package with Expedia is one of the easiest ways to save. We have access to more than 550 air carriers and 1,000,000 properties spread across the globe. With such an awesome range to select from, you'll have no trouble creating your ideal trip.
What are the top hotels in Cape Girardeau County?
For hotels in Cape Girardeau with cosy beds and friendly service, you can't go past Drury Plaza Hotel Cape Girardeau Conference Centre and Pear Tree Inn Cape Girardeau West. If you're swinging by Jackson as well, you can look forward to a relaxing night's sleep at Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel or Auburn Place Hotel And Suites.
How far in advance should I book my Cape Girardeau County holiday?
Reserving your spot early with Expedia means one less thing to worry about. Most carriers advertise tickets up to 12 months in advance. Generally, this is the cheapest time to book. If circumstances have left you booking late, discount tickets to Cape Girardeau County sometimes occur in the weeks leading up to departure.
What does an Expedia Cape Girardeau County travel package include?
Choose from a combination of rental cars, hotels and flights. Once you've made your booking, you can add activities and tours. Want to pick your fare class? That's also possible. The choice is all yours when it comes to planning your perfect Cape Girardeau County getaway.
What should I know before booking a Cape Girardeau County travel package?
You'll save plenty with an Expedia travel package. Combine your flights, rental cars and hotels and land exciting discounts. Hotels aren't your only option, though. We have oceanfront condos, city apartments and everything in between!
Can I choose my airline with a Cape Girardeau County Expedia holiday package?
Definitely. Expedia has more than 550 airline partners to choose from around the world. With so much choice, finding the right carrier to bring you to Cape Girardeau County will be a breeze.
If I'm not able to travel, can I cancel my Cape Girardeau County holiday package?
Yes, you can. We realise life happens, so we're here to help if you have to make changes to your Cape Girardeau County holiday package. You may be able to cancel or amend your itinerary for free if you've booked in the last 24 hours. Your airline, hotel or car rental company may charge you a fee if you booked more than 24 hours ago. Take a look at our Customer Service Portal for more information. Also, check your itinerary for the finer details on change fees.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.