The Best Hotels in Downtown Clayton, St. Louis - 2026 Updated Prices

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Compare popular hotels in Downtown Clayton

Property	Property class	Guest rating
AC Hotel St. Louis Clayton	3.0 star property	9.2 Wonderful 346 reviews	View
Clayton Plaza Hotel & Extended Stay	3.5 star property	9.0 Wonderful 3,273 reviews	View
The Ritz-Carlton, St. Louis	5.0 star property	9.2 Wonderful 575 reviews	View
Le Méridien St. Louis Clayton	4.0 star property	8.8 Excellent 745 reviews	View
Seven Gables, St. Louis West, a Tribute Portfolio Hotel	3.5 star property	8.4 Very good 597 reviews	View

Where to stay in Downtown Clayton

Find the best Downtown Clayton areas for the activities you enjoy most.

The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

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A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

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An ornate hall with arched ceilings and intricate patterns.

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

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A modern building with a brick facade, parked cars, and a flower bed with tulips.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

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A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

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Top Downtown Clayton Hotel Reviews

Live by Loews - St.Louis

10/10 Excellent

"Very nice and we were about to walk to many places near by. Would definitely stay again!"

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

10/10 Excellent

"An absolute gem in St. Louis! I cannot recommend the Magnolia Hotel enough—you truly won't be disappointed! The hotel itself is lovely, featuring rooms that are beautifully appointed and immaculately clean. What really sets this place apart, though, is the exceptional service. A special shout-out to the gentlemen working the night shift on Wednesday night, who went above and beyond and made the stay extra special. To top it all off, the breakfast was amazing! I didn't have nearly enough time to explore the city, but I will definitely be back. Five stars!"

Clayton Plaza Hotel & Extended Stay

8/10 Good

"Although the hotel was nice, I didn’t realize it was downtown much less that parking was in a parking garage. It was completely on the other side, which you had to go around a couple blocks to get to it. Even thought it was attached, the elevator to the garage was out of order. So it was impossible to take your stuff out the door to the parking garage unless you were on that side of the building or on that floor. The game place was closed. Breakfast was really good. Wished it wasn’t dine in only though."

Renaissance St. Louis Airport Hotel

8/10 Good

"Hotel is very nice and well situated to the airport. Check in was very smooth and the bar is very nice and spacious. The only downside side is that you have to pay for parking and since they allow extended parking for people going to the airport it can be a very long walk from your parking space to the entrance to the hotel. That is particularly bad if it is raining or other inclement weather."

Frequently asked questions

What's it like in Downtown Clayton?

Travellers to the Downtown Clayton neighbourhood in St. Louis will be sure to enjoy their stay.

What's a favourite hotel to stay in Downtown Clayton?

Based on our traveller data, Clayton Plaza Hotel & Extended Stay is one of the top choices for your stay in Downtown Clayton. This hotel offers free breakfast and an indoor pool. Other good options for your stay in the area include Le Méridien St. Louis Clayton and AC Hotel St. Louis Clayton.

How many hotels can I expect to find in the Downtown Clayton area?

Expedia has 5 Downtown Clayton hotels and other accommodation options, and one might make a good home base for venturing out into the greater St. Louis area.

If I need to cancel my hotel reservation in Downtown Clayton, will I receive a refund?

Yes! Most hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the top deals on offer in Downtown Clayton.

What can I see and do in this St. Louis neighbourhood?

St. Louis Zoo, Shaw Park Tennis Center and Saint Louis Galleria Mall are just a few of the places to visit in and around Downtown Clayton. While you're out sightseeing, Tao Tennis Center and Center of Creative Arts are a couple of additional sights to visit in St. Louis.

How can I get around Downtown Clayton and the greater St. Louis area?

Ready to get out and explore the city? Clayton Station is the closest metro station.

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Our top choices for Downtown Clayton hotels

1. Clayton Plaza Hotel & Extended Stay

2. AC Hotel St. Louis Clayton

3. Le Méridien St. Louis Clayton

4. Seven Gables, St. Louis West, a Tribute Portfolio Hotel

5. The Ritz-Carlton, St. Louis

6. Hampton Inn & Suites Clayton/St. Louis-Galleria Area

7. Pear Tree Inn St. Louis Airport

8. Drury Inn & Suites St. Louis Airport

9. Hyatt Select St. Louis Airport

10. The Knight Center at Washington University

11. Wingate by Wyndham St. Louis Airport

12. Courtyard by Marriott St. Louis Brentwood

13. Moonrise Hotel

14. Renaissance St. Louis Airport Hotel

15. SpringHill Suites St. Louis Brentwood

16. Hampton Inn By Hilton St Louis Airport

17. Holiday Inn Express & Suites St Louis Airport by IHG

18. Drury Plaza Hotel St. Louis Brentwood

19. Drury Plaza Hotel St. Louis at the Arch

20. The Cheshire

Compare popular hotels in Downtown Clayton

Where to stay in Downtown Clayton

Downtown St. Louis

Clayton

Downtown West

Central West End

Creve Coeur

Top Downtown Clayton Hotel Reviews

Live by Loews - St.Louis

Frequently asked questions

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