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Search Hotels in Downtown Clayton, St. Louis

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Our top choices for Downtown Clayton hotels

Exterior
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
Downtown Clayton
8.8 out of 10, Excellent, (3045)
"Great stay‼️"
United States
Calvin
The price is Rp1.581.545
Rp1.846.264 total
includes taxes & fees
30 Jan - 31 Jan 2026
Clayton Plaza Hotel & Extended Stay
Property entrance
Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Seven Gables, St. Louis West, a Tribute Portfolio Hotel
3.5 star property
Downtown Clayton
8.4 out of 10, Very good, (577)
"Love this place."
United States
Robert
The price is Rp2.197.001
Rp2.724.424 total
includes taxes & fees
4 Jan - 5 Jan 2026
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Outdoor pool, open 8:00 AM to 8:30 PM, pool umbrellas, pool loungers
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Downtown Clayton
8.8 out of 10, Excellent, (681)
"The gym was amazing! "
United States
Hannah
The price is Rp2.267.439
Rp2.669.637 total
includes taxes & fees
3 Jan - 4 Jan 2026
Le Méridien St. Louis Clayton
2 bars/lounges, rooftop bar
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton
3.0 star property
Downtown Clayton
9.0 out of 10, Wonderful, (230)
"Staff was amazing "
Canada
Sham
The price is Rp2.180.230
Rp2.545.158 total
includes taxes & fees
25 Jan - 26 Jan 2026
AC Hotel St. Louis Clayton
Meeting facility
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Downtown Clayton
9.2 out of 10, Wonderful, (554)
"The stay was ok even though nothing was explained to be. The hours of restaurant, where the gym is located about the bar in the room nothing. "
United States
Shemelle
The price is Rp8.368.729
Rp9.769.486 total
includes taxes & fees
1 Jan - 2 Jan 2026
The Ritz-Carlton, St. Louis
Lobby
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 13.2 km from Downtown Clayton
8.4 out of 10, Very good, (4032)
"Staff was supper nice and it all went so smooth."
United States
Brayden
The price is Rp2.163.459
Rp2.551.346 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hyatt Regency St. Louis at The Arch
Bar (on property)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis, 12.8 km from Downtown Clayton
8.8 out of 10, Excellent, (1178)
"Great staff and location"
United States
Robin or David
The price is Rp1.628.436
Rp1.936.683 total
includes taxes & fees
25 Jan - 26 Jan 2026
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Exterior
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
25 km from Downtown Clayton
8.0 out of 10, Very good, (1001)
"very friendly staff and good location "
United States
Heather
The price is Rp1.626.116
Rp1.868.845 total
includes taxes & fees
25 Jan - 26 Jan 2026
Hampton Inn St. Charles St. Peters
Exterior
Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis, 13.1 km from Downtown Clayton
8.8 out of 10, Excellent, (1020)
"Staff were real nice. Accommodating. "
United States
Tim
The price is Rp1.797.851
Rp2.120.187 total
includes taxes & fees
14 Jan - 15 Jan 2026
Hilton Pennywell St. Louis at the Arch
Rooftop terrace
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 13.1 km from Downtown Clayton
9.4 out of 10, Exceptional, (3292)
"Comfortable stay "
United States
Jose
The price is Rp2.414.856
Rp2.823.666 total
includes taxes & fees
5 Jan - 6 Jan 2026
Drury Plaza Hotel St. Louis at the Arch
Ballroom
The Wildwood Hotel

The Wildwood Hotel

The Wildwood Hotel
3.5 star property
26.5 km from Downtown Clayton
9.2 out of 10, Wonderful, (1613)
"Very nice hotel"
United States
sharon
The Wildwood Hotel
Terrace/patio
Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
2.2 km from Downtown Clayton
9.4 out of 10, Exceptional, (844)
"Clean, would stay again."
United States
Eryka
The price is Rp1.696.387
Rp2.081.146 total
includes taxes & fees
1 Jan - 2 Jan 2026
Courtyard by Marriott St. Louis Brentwood
Lobby
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
10.4 km from Downtown Clayton
9.4 out of 10, Exceptional, (2770)
"Very clean and will definitely stay there again next time!"
United States
Tonya
The price is Rp1.509.222
Rp1.776.720 total
includes taxes & fees
5 Jan - 6 Jan 2026
Pear Tree Inn St. Louis Airport
Lobby
Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown
3.0 star property
Downtown West, 12.2 km from Downtown Clayton
8.0 out of 10, Very good, (624)
"Great stay "
United States
Kevin
The price is Rp1.306.461
Rp1.527.632 total
includes taxes & fees
14 Jan - 15 Jan 2026
Home2 Suites by Hilton St. Louis Downtown
Exterior
Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 12.9 km from Downtown Clayton
8.8 out of 10, Excellent, (1263)
"Very cool hotel, rooms were clean and nice design, the food at the bar/restaurant was fantastic!!!"
United States
Cullin
The price is Rp1.911.559
Rp2.273.399 total
includes taxes & fees
15 Jan - 16 Jan 2026
Embassy Suites by Hilton St. Louis Downtown
Room, 2 Queen Beds, Accessible, Non Smoking (Mobility, Tub W/Grab Bars) | Desk, laptop workspace, iron/ironing board, free cots/infant beds
Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
2.5 star property
10.4 km from Downtown Clayton
9.2 out of 10, Wonderful, (1505)
"Good transport to and from car rental, a plus "
United States
Ralph
The price is Rp1.810.429
Rp2.131.563 total
includes taxes & fees
1 Jan - 2 Jan 2026
Wingate by Wyndham St. Louis Airport
Exterior
Moonrise Hotel

Moonrise Hotel

Moonrise Hotel
4.0 star property
3.4 km from Downtown Clayton
9.0 out of 10, Wonderful, (1919)
"Great place"
United States
Edward
The price is Rp2.072.955
Rp2.465.346 total
includes taxes & fees
1 Jan - 2 Jan 2026
Moonrise Hotel
Indoor pool, open 6:00 AM to 10:00 PM, pool loungers
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
2.5 star property
Downtown St. Louis, 13.2 km from Downtown Clayton
8.8 out of 10, Excellent, (1193)
"The staff was probably the best part of the stay. "
United States
Ja Nelle
The price is Rp1.636.514
Rp1.913.560 total
includes taxes & fees
14 Jan - 15 Jan 2026
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Daily cooked-to-order breakfast for a fee
River City Casino & Hotel

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
14.7 km from Downtown Clayton
9.0 out of 10, Wonderful, (1455)
"Everything was absolutely wonderfull"
United States
Suada
The price is Rp1.660.161
Rp2.176.373 total
includes taxes & fees
5 Jan - 6 Jan 2026
River City Casino & Hotel
Lobby sitting area
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
16.4 km from Downtown Clayton
8.0 out of 10, Very good, (1060)
"While the water constantly ran in the bathtub, the staff was amazing, the beds were comfy enough, the free breakfast was filling and checkout was easy. "
United States
jessica
The price is Rp1.425.535
Rp1.646.577 total
includes taxes & fees
4 Jan - 5 Jan 2026
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Downtown Clayton

Find the best Downtown Clayton areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Busch Stadium to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

Berkeley

Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Top Downtown Clayton Hotel Reviews

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

10/10 Excellent
"Absolutely beautiful hotel!!! Highly recommend!"
Matthew 2-night trip
Posted 1 month ago
The Ritz-Carlton, St. Louis

Frequently asked questions

What's it like in Downtown Clayton?
Travellers to the Downtown Clayton neighbourhood in St. Louis will be sure to enjoy their stay.
What's a favourite hotel to stay in Downtown Clayton?
Based on Expedia customer reviews, AC Hotel St. Louis Clayton is the highest ranked property in Downtown Clayton. This hotel offers 2 restaurants and 2 bars. Other favourite options in the area include The Ritz-Carlton, St. Louis and Clayton Plaza Hotel & Extended Stay.
How many hotels can I expect to find in the Downtown Clayton area?
Expedia has 5 Downtown Clayton hotels and other accommodation options, and one might make a good home base for venturing out into the greater St. Louis area.
If I need to cancel my hotel reservation in Downtown Clayton, will I receive a refund?
Yes! Most hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the top deals on offer in Downtown Clayton.
What can I see and do in this St. Louis neighbourhood?
Shaw Park Tennis Center, Saint Louis Galleria Mall and Tao Tennis Center are just a few of the places to visit in and around Downtown Clayton. While you're out sightseeing, Center of Creative Arts and Chapel of St. Timothy And St. Titus, Concordia Seminary are a couple of additional sights to visit in St. Louis.
How can I get around Downtown Clayton and the greater St. Louis area?
Ready to get out and explore the city? Clayton Station is the closest metro station.