Photo by Mark Rentz

Find hotels in Isla Santa María from Rp1.356.345

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
27 Dec - 28 Dec
Tomorrow
28 Dec - 29 Dec
Next weekend
2 Jan - 4 Jan
In two weeks
9 Jan - 11 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Isla Santa María hotels

Exterior
Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel
4.5 star property
Puerto Ayora
9.2 out of 10, Wonderful, (88)
Discover Puerto Ayora's natural wonders from this luxurious beachfront hotel. Enjoy the outdoor pool, indulge in spa massages, or savour meals at the restaurant after exploring nearby Playa de los Alemanes and Esplanade.
"Beautiful resort, impeccably clean, very kind and enthusiastic staff. Delicious restaurant. 5 stars all around, we will definitely return!"
United States
Jonathan
The price is Rp9.442.372
Rp10.412.229 total
20 Jan - 21 Jan 2026
Finch Bay Galapagos Hotel
Restaurant
Enchanted Galapagos Lodge

Enchanted Galapagos Lodge

Enchanted Galapagos Lodge
3.0 star property
Bella Vista
8.0 out of 10, Very good, (3)
"We booked this hotel under the pretense that the resturant was open for business and the taxi price rate was similar to the rest of Ecuador or the reviews in our travel book. Hotel served a nice breakfast BUT no other food is available so one must go into Puerto Ayora for lunch and dinner. The taxi rate to and from hotel into town can be anywhere from $10-$15 each way..... if u want to freshen up after a long tour that will be 4 taxi rides......$40-$60 per day. Lawrence offered us a ride...
United States
anne
Enchanted Galapagos Lodge
Free daily continental breakfast
Hotel Cucuve

Hotel Cucuve

Hotel Cucuve
4.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (269)
Wake up to complimentary continental breakfast at this Puerto Ayora B&B before exploring nearby Galápagos National Park. Enjoy snorkelling adventures, relax on the terrace, or grab a bite at the snack bar. The Fishing Piers and Gus Angermeyer Ferry Terminal are just minutes away.
"Wonderful staff, beautiful room, delicious breakfast!"
United States
Ashley
The price is Rp3.683.900
Rp4.052.290 total
13 Jan - 14 Jan 2026
Hotel Cucuve
Suite, 1 Bedroom | Free minibar, in-room safe, desk, free WiFi
Hotel Santa Fe

Hotel Santa Fe

Hotel Santa Fe
4.0 star property
Puerto Ayora
9.6 out of 10, Exceptional, (14)
Explore iconic Puerto Ayora from this hotel where hiking trails and snorkelling await nearby. Free breakfast, bike rentals, and room service enhance your island stay, with Las Ninfas Lagoon just moments away.
"Beautiful hotel, with amazing staff, and great location "
United States
Steven
The price is Rp2.845.813
Rp3.130.478 total
31 Dec - 1 Jan 2026
Hotel Santa Fe
Front of property
Blu Galapagos Sustainable Waterfront Lodge

Blu Galapagos Sustainable Waterfront Lodge

Blu Galapagos Sustainable Waterfront Lodge
4.0 star property
Puerto Ayora
8.8 out of 10, Excellent, (122)
Experience waterfront luxury at this sustainable lodge adjacent to Galápagos National Park. Enjoy international cuisine at Almar by Isla Grill, relax on the terrace, or borrow bikes to explore Puerto Ayora. Popular attractions like Charles Darwin Research Station and Fishing Piers await nearby.
"Beautiful property "
Canada
David
The price is Rp4.053.965
Rp4.459.361 total
13 Jan - 14 Jan 2026
Blu Galapagos Sustainable Waterfront Lodge
Exterior
Hotel Ninfa

Hotel Ninfa

Hotel Ninfa
3.5 star property
Puerto Ayora
8.4 out of 10, Very good, (218)
This Puerto Ayora hotel offers an outdoor pool, hot tub, and rejuvenating massages for unwinding after adventures. Conveniently located near Esplanade and the Gus Angermeyer Ferry Terminal, guests enjoy the on-site bar and coffee shop in well-maintained surroundings.
"Great, clean, and convenient place. Good location close to docks. Walkable to the Main Street. Hotel rooms clean with good service and breakfast. We stayed here two seperate times during Galapagos and would stay again. "
Canada
Aly
Hotel Ninfa
Spa
Hotel Flamingo

Hotel Flamingo

Hotel Flamingo
3.5 star property
Puerto Ayora
8.8 out of 10, Excellent, (112)
Located steps from Galápagos National Park, this hotel offers a rejuvenating hot tub and free breakfast. Unwind at the bar or explore nearby Gus Angermeyer Ferry Terminal, then return to the peaceful garden terrace.
"Amazing place to stay!"
United States
Eszter
Hotel Flamingo
Ninfas Suite | Terrace/patio
Casa del Lago Lodging House

Casa del Lago Lodging House

Casa del Lago Lodging House
2.0 star property
Puerto Ayora
7.8 out of 10, Good, (13)
Surrounded by natural wonders, this Puerto Ayora B&B offers easy access to Las Ninfas Lagoon and Esplanade. Enjoy hiking trails and kayaking adventures, then relax in the garden or terrace with free WiFi.
"The Tortuga bay suite is right by the street so you hear the street noise until about 10:30pm on workdays and about 11:30pm on a Friday. The air conditioner doesn’t work well. It makes a noise at night and is quite disturbing. With the many mosquitoes, we could not open the windows and it was quite a terrible experience to sleep at night. The soap and shampoo/body wash are diluted. The fridge is incredibly noisy and you cannot sleep with it being on. The plates are dirty and require extra...
United States
Jingyuan
The price is Rp1.130.288
Rp1.265.922 total
7 Jan - 8 Jan 2026
Casa del Lago Lodging House
Comfort Quadruple Room | Desk, bed sheets
Grand Hotel Leon Marino Galapagos

Grand Hotel Leon Marino Galapagos

Grand Hotel Leon Marino Galapagos
3.0 star property
Puerto Ayora
8.8 out of 10, Excellent, (13)
Inviting hotel steps from Galápagos National Park offers an outdoor pool for post-exploration relaxation. Enjoy complimentary breakfast at the café, sip drinks at the bar, and take advantage of laundry service while exploring nearby Fishing Piers.
"Staff was very friendly and location convenient. Modern interior."
United Kingdom
Marc
The price is Rp1.547.244
Rp1.547.244 total
2 Jan - 3 Jan 2026
Grand Hotel Leon Marino Galapagos
Front of property
Lava House Hostal

Lava House Hostal

Lava House Hostal
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (53)
This stylish Puerto Ayora hostal sits moments from Galápagos National Park with hiking trails and kayaking nearby. Free continental breakfast energises morning explorations, while the garden and terrace offer peaceful relaxation after outdoor adventures.
"I stayed here twice. Both times highly satisfactory. Staff was very friendly and accommodatding. The rooms and garden area are in excellent upkeep and pleasant to hang out in hammocks or seating arrangements. The owners are very kind people, who even helped me organize a free ride back to the airport upon my departure (a relative happened to also take a flight off the island). I highly recommend this establishment. "
United States
Irmgard
Lava House Hostal
Outdoor pool
Hotel Villa Escalesia Galapagos

Hotel Villa Escalesia Galapagos

Hotel Villa Escalesia Galapagos
2.5 star property
Puerto Ayora
10.0 out of 10, Exceptional, (3)
Steps from Galápagos National Park, this Puerto Ayora hotel provides a refreshing outdoor pool and soothing hot tub. Start your day with complimentary breakfast before exploring nearby Fishing Piers and Gus Angermeyer Ferry Terminal.
"Hidden gem of Santa Cruz"
United States
Robert
The price is Rp6.102.094
Rp6.102.094 total
20 Jan - 21 Jan 2026
Hotel Villa Escalesia Galapagos
Suite, Sea View | Beach/ocean view
Angermeyer Waterfront Inn

Angermeyer Waterfront Inn

Angermeyer Waterfront Inn
3.5 star property
Puerto Ayora
9.4 out of 10, Exceptional, (125)
Set along the waterfront in Puerto Ayora, this hotel with marina access sits steps from Galápagos National Park. Enjoy complimentary cooked-to-order breakfast each morning before heading out for kayaking, snorkelling, or scuba diving nearby.
"More 4 stars for the location, the rooms were ok, beds were extremely firm, we had an issue that was difficult to try and get resolved and never actually was resolved, food at their restaurant was great including the complementary breakfast, very nice that it’s five minutes from an amazing beach and 15 minutes from Las Grietas "
United States
Benjamin
The price is Rp4.595.314
Rp5.054.845 total
8 Jan - 9 Jan 2026
Angermeyer Waterfront Inn
Children’s play area – outdoor
Hostal Casa Eden Galapagos

Hostal Casa Eden Galapagos

Hostal Casa Eden Galapagos
3.0 star property
Puerto Ayora
8.8 out of 10, Excellent, (6)
Perfectly positioned beside Galápagos National Park, this inviting hostal offers complimentary full breakfast and WiFi. Nearby attractions include Fishing Piers and Charles Darwin Research Station. Enjoy daily housekeeping and explore local snorkelling spots during your island stay.
"breakfast was wonderful and Gloria was very kind"
Canada
Florence
The price is Rp1.220.710
Rp1.220.710 total
28 Dec - 29 Dec
Hostal Casa Eden Galapagos
Hallway
Hotel Brisas Del Pacifico

Hotel Brisas Del Pacifico

Hotel Brisas Del Pacifico
2.5 star property
Puerto Ayora
7.4 out of 10, Good, (80)
Wake to the sounds of nature at this serene Puerto Ayora hotel. Just moments from Fishing Piers and Las Ninfas Lagoon, it offers garden spaces, a welcoming terrace, and 24-hour assistance for your island exploration needs.
"Suprise by quality/price.front desk Denise very helpfulll"
Canada
regis
Hotel Brisas Del Pacifico
Terrace/patio
Lonesome George Ecolodge

Lonesome George Ecolodge

Lonesome George Ecolodge
2.5 star property
Puerto Ayora
9.2 out of 10, Wonderful, (23)
Experience Puerto Ayora's natural beauty at this welcoming hostal near Fishing Piers and Gus Angermeyer Ferry Terminal. Enjoy hiking trails, kayaking adventures, and mountain biking excursions. The garden, terrace, and bike shuttle enhance your island exploration.
"A cute hostel/hotel just two short blocks from the main road that runs along the harbor. Hot water and a/c worked well, and there was drinking water available for tea/coffee/water bottles. I did not take advantage of tour opportunites, but they were readily available at the front desk, as were bike and kayak rentals. Thanks for a great stay!"
United States
BOHDANNA
The price is Rp1.674.500
Rp1.674.500 total
27 Jan - 28 Jan 2026
Lonesome George Ecolodge
Terrace/patio
ECO HOSTAL ISLA AZUL

ECO HOSTAL ISLA AZUL

ECO HOSTAL ISLA AZUL
3.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (2)
Wake up to a complimentary local cuisine breakfast at this Puerto Ayora hotel before exploring nearby Fishing Piers and Gus Angermeyer Ferry Terminal. Free WiFi and daily housekeeping enhance your Galápagos adventure.
"Loved that they had purified water to refill your water bottle instead of buying plastic! Staff were incredibly kind. "
Canada
Jaclyn
The price is Rp2.360.710
Rp3.064.000 total
28 Dec - 29 Dec
ECO HOSTAL ISLA AZUL
Exterior
Maidith Galapagos Inn

Maidith Galapagos Inn

Maidith Galapagos Inn
3.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (102)
Discover this welcoming family-friendly hotel with outdoor and children's pools just steps from Galápagos National Park. Enjoy complimentary breakfast, convenient snack options at the café and deli, plus easy access to Fishing Piers and Gus Angermeyer Ferry Terminal.
"Super experience all around. The host and staff were polite and helpful"
United States
Arwen R
The price is Rp2.109.870
Rp2.109.870 total
1 Jan - 2 Jan 2026
Maidith Galapagos Inn
Courtyard
Hotel Red Booby

Hotel Red Booby

Hotel Red Booby
3.0 star property
Puerto Ayora
7.2 out of 10, Good, (20)
Located in Puerto Ayora, this inviting hotel offers a tranquil outdoor pool and complimentary breakfast. Just moments from natural wonders, with convenient access to Gus Angermeyer Ferry Terminal and Fishing Piers.
"Staff was very friendly and very helpful when we had some issues (issues not related to the hotel stay). The staff tried their best to be accommodating!"
United States
John B
Hotel Red Booby
Property grounds
Hostal España

Hostal España

Hostal España
3.0 star property
Puerto Ayora
7.6 out of 10, Good, (122)
Enjoy a refreshing swim in the outdoor pool before dining at the café or bar of this hostal. Convenient amenities include complimentary breakfast and parking. Nearby attractions like Gus Angermeyer Ferry Terminal and Fishing Piers enhance your Galapagos adventure.
"Good experience. "
United States
Mario David Paz
Hostal España
Front of property
Villa Galapagos

Villa Galapagos

Villa Galapagos
2.5 star property
Puerto Ayora
6.0 out of 10, (1)
Embracing the wonders of Puerto Ayora, this holiday home offers daily housekeeping and premium TV channels. Relax with free WiFi after exploring nearby Fishing Piers and Gus Angermeyer Ferry Terminal.
"着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。"
Japan
アオアシカツオドリ
Villa Galapagos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Isla Santa María attractions

Bedtime in the Galapagos #golden
Photo by Delen Wong
Open Photo by Delen Wong

Punta Suarez

Explore the great outdoors at Punta Suarez, a lovely green space in Isla Santa María. Wander the seaside and white-sand beaches while you're in the area.
See properties
Swimming with sea turtles was one of the many amazing moments of my Galapagos adventure. Like most of the other animals, they went about their business without seeming to even notice the people around.
Photo by Tove Martin
Open Photo by Tove Martin

Post Office Bay

Commune with nature and explore the great outdoors at Post Office Bay during your travels in Isla Santa María. While you're in the area, wander around the natural setting.
See properties

Learn more about Isla Santa María

Explore attractions like Galápagos National Park and Post Office Bay as you discover things to see and do in Isla Santa María.

See all hotels in Isla Santa María
A greater flamingo searching for dinner. There were a few hundred of them wading in the lagoon.
Photo by Mark Rentz
Open Photo by Mark Rentz

Top Isla Santa María Hotel Reviews

Hotel Fiesta

Hotel Fiesta

10/10 Excellent
"Staff was efficient room was clean "
Jonathan 3-night trip
Posted 2 weeks ago
Hotel Fiesta

More cheap stays in Isla Santa María

Hostal Casa Cascada

Hostal Casa Cascada

Pje. 1 Puerto Ayora Galápagos Islands
The price is Rp378.573 per night from 18 Jan to 19 Jan
Rp378.573
Rp755.246 total
18 Jan - 19 Jan 2026
9.6/10 Exceptional! (4 reviews)

Frequently asked questions

Where is the best place for a stay in Isla Santa María?
Located 38.3 mi (61.7 km) from the heart of Isla Santa María, Hotel Fiesta is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are Capitan Max B&B and El Barranco Galapagos. See all available top hotels, or vacation rentals in Isla Santa María.
What are some of the best holiday rentals that Isla Santa María has to offer?
Villa Galapagos: This holiday home rental outside of Isla Santa María is located near the beach, and offers a private garden, air conditioning and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave. See all vacation rentals in Isla Santa María.
If I need to cancel my hotel reservation in Isla Santa María, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Isla Santa María.
What is staying in Isla Santa María like?
Travellers to Isla Santa María will find plenty to explore and enjoy. There are 208 hotels and other accommodation options in the larger region. Find out more about Isla Santa María.
What is there to see in Isla Santa María?
Favourite places to visit include Galápagos National Park, Post Office Bay and Punta Suarez. Take a look at what more there is to see and do in Expedia's Isla Santa María guide.
What's the seasonal weather in Isla Santa María?
The hottest months are usually March and February, with an average temperature of 26°C, while the coldest months are September and October, with an average of 22°C. Average annual precipitation for Isla Santa María is 319 mm.