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11 Sept - 13 Sept
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18 Sept - 20 Sept

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Our top choices for Isle of Palms hotels

A spacious living area with a high ceiling, a fireplace, and a bar area in the background.

1. Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
Isle of Palms
9.6 out of 10, Exceptional, (594 reviews)
"Great stay"
United States
Michaelanne
The price is Rp2.411.564
Rp2.737.126 total
includes taxes & fees
2 Oct - 3 Oct
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
A multi-story hotel with a modern design, featuring a prominent "HYATT PLACE" sign.

2. Hyatt Place Jacksonville Airport

Hyatt Place Jacksonville Airport
3.0 star property
31.1 km from Isle of Palms
9.0 out of 10, Wonderful, (2,561 reviews)
"Good place to stay."
United States
Henry
The price is Rp1.678.566
Rp1.905.174 total
includes taxes & fees
29 Sept - 30 Sept
Hyatt Place Jacksonville Airport
A spacious lobby with a glass floor, a reception desk, and a view of the ocean.

3. Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
Oceanfront, 4.6 km from Isle of Palms
9.0 out of 10, Wonderful, (4,457 reviews)
"Enjoyed our overnight stay"
United States
Melissa
The price is Rp2.631.576
Rp2.986.839 total
includes taxes & fees
10 Sept - 11 Sept
Margaritaville Jacksonville Beach
A modern restaurant with a bar area, wooden ceiling, and large windows.

4. Hilton Jacksonville at Mayo Clinic near Beaches

Hilton Jacksonville at Mayo Clinic near Beaches
4.5 star property
2.1 km from Isle of Palms
9.4 out of 10, Exceptional, (351 reviews)
"Excellent hotel and staff."
United States
Kristen
The price is Rp2.740.189
Rp3.110.114 total
includes taxes & fees
20 Sept - 21 Sept
Hilton Jacksonville at Mayo Clinic near Beaches
An outdoor seating area with a fire pit, wicker furniture, and a covered patio.

5. TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
3 km from Isle of Palms
9.2 out of 10, Wonderful, (656 reviews)
"Comfy beds"
United States
Tiffany
The price is Rp2.098.208
Rp2.381.465 total
includes taxes & fees
17 Sept - 18 Sept
TownePlace Suites by Marriott Jacksonville East
A hotel room with two beds, a desk with a computer, a chair, and a colorful carpet.

6. Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
3.3 km from Isle of Palms
9.2 out of 10, Wonderful, (1,000 reviews)
"The staff was nice, and the breakfast was very good,"
United States
Jose
The price is Rp2.080.576
Rp2.361.453 total
includes taxes & fees
16 Sept - 17 Sept
Holiday Inn Express Jacksonville Beach by IHG
A covered entrance with a dark tiled floor, white columns, and a green bench.

7. Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
3.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1,222 reviews)
"I loved everything about this hotel! Me and my family definitely enjoyed the stay ! Highly recommended"
United States
Torresia
The price is Rp2.083.221
Rp2.364.455 total
includes taxes & fees
27 Sept - 28 Sept
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
A beach with a sandy shore, waves, and buildings in the background.

8. Best Western Oceanfront

Best Western Oceanfront
3.0 star property
Oceanfront, 4.4 km from Isle of Palms
9.0 out of 10, Wonderful, (1,000 reviews)
"The location was great."
United States
Shawna
The price is Rp2.147.401
Rp2.437.300 total
includes taxes & fees
10 Sept - 11 Sept
Best Western Oceanfront
A modern outdoor seating area with white wicker chairs, a glass fire pit with burning wood, and a view of palm trees and a building in the background.

9. Element by Marriott Jacksonville Beach

Element by Marriott Jacksonville Beach
3.0 star property
Oceanfront, 4.2 km from Isle of Palms
9.6 out of 10, Exceptional, (579 reviews)
"Nice lodging a block from the beach. Great food nearby."
United States
Nick
The price is Rp2.540.160
Rp2.883.081 total
includes taxes & fees
20 Sept - 21 Sept
Element by Marriott Jacksonville Beach
An outdoor patio area with wicker furniture, a fire feature, and string lights.

10. Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel
4.0 star property
10.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1,000 reviews)
"Great stay for the price. Definitely recommend."
United States
Danielle
The price is Rp2.180.549
Rp2.474.924 total
includes taxes & fees
11 Sept - 12 Sept
Sheraton Jacksonville Hotel
A modern living room with a sectional sofa, a coffee table, and vibrant abstract art on the walls.

11. Weekly Inn

Weekly Inn
2.0 star property
14.9 km from Isle of Palms
7.8 out of 10, Good, (1,477 reviews)
"I enjoyed my stay here. it was clean and for the price it wasn’t bad."
United States
Presley
The price is Rp666.490
Rp756.467 total
includes taxes & fees
16 Sept - 17 Sept
Weekly Inn
An outdoor patio with seating, a fire pit, and string lights.

12. Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
9.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1,162 reviews)
"Certainly located and very clean."
United States
Gary
The price is Rp2.242.790
Rp2.545.566 total
includes taxes & fees
13 Sept - 14 Sept
Hyatt Place Jacksonville / St. Johns Town Center
A spacious lobby with a reception desk, seating area, and large windows.

13. Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1,005 reviews)
"Family of 5 stayed comfortably! Very accommodating and friendly! Room was clean, pool was also fun!"
United States
Brooke
The price is Rp2.279.553
Rp2.541.701 total
includes taxes & fees
8 Oct - 9 Oct
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
A modern dining area with wooden tables and chairs, pendant lighting, and artwork on the walls.

14. Fairfield Inn & Suites by Marriott Jacksonville Beach

Fairfield Inn & Suites by Marriott Jacksonville Beach
3.0 star property
Oceanfront, 5 km from Isle of Palms
8.6 out of 10, Excellent, (980 reviews)
"clean room nice beach location"
United States
Anne
The price is Rp2.159.136
Rp2.450.619 total
includes taxes & fees
20 Sept - 21 Sept
Fairfield Inn & Suites by Marriott Jacksonville Beach
A spacious lobby with a reception desk, large wooden columns, and a central table with a vase.

15. Wyndham Garden Jacksonville

Wyndham Garden Jacksonville
3.0 star property
15.5 km from Isle of Palms
7.8 out of 10, Good, (2,048 reviews)
"The room was spotless and the bed was very comfortable"
United States
Maria
The price is Rp1.318.874
Rp1.496.921 total
includes taxes & fees
16 Sept - 17 Sept
Wyndham Garden Jacksonville
A lobby with a reception desk, seating area, and a staircase.

16. Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
3.9 km from Isle of Palms
9.0 out of 10, Wonderful, (1,012 reviews)
"Plesurable stay"
United States
Sam
The price is Rp1.851.360
Rp2.101.293 total
includes taxes & fees
20 Sept - 21 Sept
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
A hotel lobby with a bar area, seating arrangements, and a reception desk.

17. Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
3 km from Isle of Palms
9.0 out of 10, Wonderful, (1,005 reviews)
"Great place to stay."
United States
Patsy
The price is Rp2.077.286
Rp2.357.719 total
includes taxes & fees
4 Oct - 5 Oct
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
A modern kitchen with dark cabinets, a marble countertop, and a built-in oven. There is a dining area with a table and chairs, and a flat-screen TV mounted above the fireplace.

18. Baymont by Wyndham Jacksonville/Butler Blvd

Baymont by Wyndham Jacksonville/Butler Blvd
2.5 star property
16.4 km from Isle of Palms
8.2 out of 10, Very good, (1,470 reviews)
"Thanks for a friendly nice stay"
United States
Robert
The price is Rp1.169.002
Rp1.326.818 total
includes taxes & fees
4 Oct - 5 Oct
Baymont by Wyndham Jacksonville/Butler Blvd
A spacious hotel atrium with multiple floors, a central staircase, and lush indoor plants.

19. Embassy Suites by Hilton Jacksonville Baymeadows

Embassy Suites by Hilton Jacksonville Baymeadows
3.5 star property
14.2 km from Isle of Palms
8.4 out of 10, Very good, (1,493 reviews)
"The room was clean, breakfast was great, and staff was great!"
United States
Anthony
The price is Rp2.081.987
Rp2.363.056 total
includes taxes & fees
13 Sept - 14 Sept
Embassy Suites by Hilton Jacksonville Baymeadows
An outdoor seating area with a fire pit, chairs, and tables.

20. Home2 Suites by Hilton Jacksonville Airport

Home2 Suites by Hilton Jacksonville Airport
3.0 star property
31.3 km from Isle of Palms
9.0 out of 10, Wonderful, (1,024 reviews)
"Great location, clean rooms, friendly staff."
United States
Daris
The price is Rp1.720.531
Rp1.952.803 total
includes taxes & fees
4 Oct - 5 Oct
Home2 Suites by Hilton Jacksonville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Isle of Palms

Find the best Isle of Palms areas for the activities you enjoy most.
A coastal cityscape at dusk with a prominent clock tower, waterfront, and historic buildings.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

A city skyline with modern skyscrapers, a prominent Wells Fargo building, and a blue bridge over a river.
Photo by Ryan Ketterman
Open Photo by Ryan Ketterman

Downtown Jacksonville

The picturesque St. Johns River meanders through the center of this hub of skyscrapers, cultural landmarks and exciting nightlife.

A sunset over a beach with waves and a pier.

Oceanfront

While visiting Oceanfront, you might make a stop by sights like Oceanfront Park and Northeast Florida Beaches.

A city skyline at night with illuminated buildings and a bridge reflecting on the water.

Southside

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

A golf course with a pond, trees, and buildings in the background.

Sawgrass

Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.

Top Isle of Palms Hotel Reviews

Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront

10/10 Excellent
"Lovely hotel"
Ovidiu 1-night trip
Posted 6 hours ago
Springhill Suites By Marriott Jacksonville Beach Oceanfront

Frequently asked questions

What is Isle of Palms like?
Travellers are sure to enjoy a stay in Jacksonville Beach's Isle of Palms neighbourhood.
What's a favourite hotel to stay in Isle of Palms?
Based on our traveller data, Residence Inn By Marriott Jacksonville - Mayo Clinic Area is one of the top choices for your stay in Isle of Palms. This hotel is a short 6-minute walk from Mayo Clinic Florida, and it offers free breakfast and an outdoor pool.
How many hotels should I expect to find in Isle of Palms?
Expedia has 38 hotels and other accommodation options in Isle of Palms to choose from, making this an ideal home base for exploring the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to view the best deals available in Isle of Palms.
What is there to do in this Jacksonville Beach neighbourhood?
A few places to visit in the area around Isle of Palms include Cradle Creek Preserve, Jacksonville Beach Golf Club and Windsor Parke Golf Club. While you're out sightseeing in Jacksonville Beach, make sure that you visit other sights such as Players by the Sea or Rhoda Martin Cultural Heritage Center.