Search Spa Hotels in Key West

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Check availability on Key West Spa Hotels

Tonight
28 Dec - 29 Dec
Tomorrow
29 Dec - 30 Dec
Next weekend
2 Jan - 4 Jan
In two weeks
9 Jan - 11 Jan

Our top choices for Key West hotels with a spa

Couples treatment room(s), facials, massages
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses
4.0 star property
Old Town Key West
8.8 out of 10, Excellent, (2955)
"Wonderful stay!"
United States
Elisa
The price is Rp4.944.129
Rp6.786.707 total
includes taxes & fees
13 Jan - 14 Jan 2026
Southernmost Beach Resort and Guesthouses
Outdoor treatment area, hot stone massages, deep-tissue massages
The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton
4.0 star property
Old Town Key West
8.6 out of 10, Excellent, (1001)
"Great hotel, great beach, had a really good stay."
United States
Cristian Mihai
The price is Rp5.478.629
Rp7.168.158 total
includes taxes & fees
13 Jan - 14 Jan 2026
The Reach Key West, Curio Collection by Hilton
Couples treatment room(s), body treatments, aromatherapy
Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa
4.0 star property
Key West Historic District
9.0 out of 10, Wonderful, (1001)
"Staff was courteous and the location is perfect for a weekend in Key West."
United States
TIMOTHY
The price is Rp6.681.255
Rp8.609.022 total
includes taxes & fees
12 Jan - 13 Jan 2026
Hyatt Centric Key West Resort and Spa
Lobby
Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
4.0 star property
Old Town Key West
9.2 out of 10, Wonderful, (1027)
"Our stay was great!"
United States
Richard
The price is Rp7.016.155
Rp8.552.676 total
includes taxes & fees
4 Jan - 5 Jan 2026
Opal Key Resort & Marina, Key West
Couples treatment room(s), body treatments, hydrotherapy, aromatherapy
Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton
4.0 star property
Old Town Key West
8.4 out of 10, Very good, (490)
"Great place"
United States
ELENA
The price is Rp8.224.809
Rp10.257.610 total
includes taxes & fees
12 Jan - 13 Jan 2026
Casa Marina Key West, Curio Collection by Hilton
Body treatments, aromatherapy, deep-tissue massages, Swedish massages
Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
4.0 star property
Key West Historic District
9.2 out of 10, Wonderful, (1004)
"Location, large rooms"
United States
george
The price is Rp7.440.808
Rp9.670.822 total
includes taxes & fees
12 Jan - 13 Jan 2026
Ocean Key Resort - A Noble House Resort
Hot tub, body treatments, hot stone massages, deep-tissue massages
Pier House Resort & Spa

Pier House Resort & Spa

Pier House Resort & Spa
4.0 star property
Key West Historic District
9.0 out of 10, Wonderful, (1010)
"All accommodations were outstanding!"
United States
Bob
Pier House Resort & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Key West Hotel Reviews

Hyatt Vacation Club at Windward Pointe, Key West

Hyatt Vacation Club at Windward Pointe, Key West

10/10 Excellent
"Stayed for 4 days. Awesome "
Rakshya 3-night trip
Posted 2 days ago
Hyatt Vacation Club at Windward Pointe, Key West

Frequently asked questions

Looking to holiday at a spa hotel in Key West?
Forget the stress of everyday life and book yourself a lush spa hotel. Travellers love Key West for the sunsets and sea views so get ready to explore the great outdoors. Enjoy the live music and bars during your holiday. Spa hotels are a great way to break out of your routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Key West?
Southernmost Beach Resort and Guesthouses is a top beach spa hotel featuring 3 pools, a fitness centre, a bar and a restaurant. Enjoy a facial, couples treatments or massage at Petite Spa. In-room massages are also available. Other popular spa hotels in Key West include The Reach Key West, Curio Collection by Hilton and Casa Marina Key West, Curio Collection by Hilton.
How many spa hotels will I find in Key West?
Among Expedia's 2776 accommodation options in Key West, there are 6 spa hotels.
What's there to see and do in Key West?
Take in the sights and attractions that Key West offers with a visit to Duval Street, Ernest Hemingway Home and Museum and Key West Lighthouse and Keeper's Quarters Museum. If you have a bit of extra time while you're in the area, you might want to check out Harry S. Truman Little White House and Audubon House and Tropical Gardens.
What is a Key West spa hotel?
Spa hotels in Key West provide lodging and have an on-site spa which offers services such as massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your holiday.