What's it like in Lake Nona Medical City?

Lake Nona Medical City is a neighbourhood that travellers like for its restaurants.

What's the best accommodation in Lake Nona Medical City?

Based on Expedia customer reviews, Aloft Orlando Lake Nona is the highest ranked property in Lake Nona Medical City. This hotel offers a restaurant and an outdoor pool. Other favourite options in the area include Residence Inn Orlando Lake Nona and Courtyard Orlando Lake Nona .

How many hotels will I find in Lake Nona Medical City?

Expedia has 5 Lake Nona Medical City hotels and other accommodation options, and one might make a good home base for venturing out into the greater Orlando area.

If I need to cancel my hotel reservation in Lake Nona Medical City, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Lake Nona Medical City.

What is there to do around this Orlando neighbourhood?

Eagle Creek Golf Club, USTA National Campus and Austin-Tindall Regional Park are just a few of the places to visit in and around Lake Nona Medical City. When you're sightseeing around the area, Lake Hart and Moss Park are a couple of other sights to visit.

The Best Hotels in Lake Nona Medical City, Orlando - 2026 Updated Prices

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Our top choices for Lake Nona Medical City hotels

1. Courtyard Orlando Lake Nona

Lake Nona Medical City

William

Rp2.742.050 total

includes taxes & fees

16 Aug - 17 Aug

2. Residence Inn Orlando Lake Nona

Lake Nona Medical City

David

Rp3.396.857 total

includes taxes & fees

23 Aug - 24 Aug

3. Aloft by Marriott Orlando Lake Nona

Lake Nona Medical City

Claribel

Rp2.837.054 total

includes taxes & fees

4 Aug - 5 Aug

4. Hyatt House Orlando Airport

Airport North, 10.5 km from Lake Nona Medical City

Shivashankar

Rp2.303.754 total

includes taxes & fees

10 Aug - 11 Aug

5. Hyatt Regency Orlando International Airport

7.7 km from Lake Nona Medical City

Beau

Rp4.437.057 total

includes taxes & fees

27 Aug - 28 Aug

6. Hampton Inn & Suites Orlando Airport @ Gateway Village

Airport North, 10.6 km from Lake Nona Medical City

Nadina

Rp1.889.078 total

includes taxes & fees

10 Aug - 11 Aug

7. Wingate by Wyndham - Orlando International Airport

Airport North, 11.1 km from Lake Nona Medical City

Emerson

Rp1.513.431 total

includes taxes & fees

3 Aug - 4 Aug

8. Wyndham Garden Orlando Airport

Belle Isle, 11.9 km from Lake Nona Medical City

Carlos

Rp1.975.370 total

includes taxes & fees

30 Jul - 31 Jul

9. Cambria Hotel Orlando Airport

11.1 km from Lake Nona Medical City

Eman

Rp1.877.101 total

includes taxes & fees

27 Aug - 28 Aug

Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility/Hearing Accessible) | Premium bedding, in-room safe, desk, blackout curtains

10. Ramada by Wyndham Suites Orlando Airport

Airport North, 10.4 km from Lake Nona Medical City

Jennifer

Rp1.568.044 total

includes taxes & fees

29 Jul - 30 Jul

11. Holiday Inn Express Orlando International Airport by IHG

11.1 km from Lake Nona Medical City

Turrell

Rp1.678.463 total

includes taxes & fees

10 Aug - 11 Aug

12. DoubleTree by Hilton Orlando Airport

Airport North, 11.2 km from Lake Nona Medical City

Mark

Rp2.060.049 total

includes taxes & fees

12 Aug - 13 Aug

13. Holiday Inn Orlando International Airport by IHG

Airport North, 10.8 km from Lake Nona Medical City

Edward

Rp1.720.692 total

includes taxes & fees

2 Aug - 3 Aug

14. avid hotel Orlando International Airport by IHG

11.2 km from Lake Nona Medical City

Jacob

Rp1.659.713 total

includes taxes & fees

25 Aug - 26 Aug

15. Country Inn & Suites by Radisson, Orlando Airport, FL

Airport North, 11 km from Lake Nona Medical City

Gregory

Rp1.567.121 total

includes taxes & fees

19 Aug - 20 Aug

Premium bedding, pillow-top beds, in-room safe, desk

16. Hyatt Place Orlando Airport

Airport North, 11 km from Lake Nona Medical City

Gregory

Rp2.101.671 total

includes taxes & fees

10 Aug - 11 Aug

17. Hampton Inn Orlando-International Airport

Airport North, 10.8 km from Lake Nona Medical City

Shezan

Rp1.894.323 total

includes taxes & fees

27 Aug - 28 Aug

18. La Quinta Inn & Suites by Wyndham Orlando Airport

Airport North, 10.9 km from Lake Nona Medical City

Kevin

Rp1.442.521 total

includes taxes & fees

23 Aug - 24 Aug

19. EVEN Hotel Orlando International Airport by IHG

Airport North, 11.1 km from Lake Nona Medical City

Angel Luis Rivera

Rp1.852.992 total

includes taxes & fees

13 Aug - 14 Aug

20. La Quinta Inn & Suites by Wyndham Orlando UCF

25.4 km from Lake Nona Medical City

Luisa

Rp1.803.241 total

includes taxes & fees

2 Aug - 3 Aug

View all properties

Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas for the activities you enjoy most. Learn more about Lake Nona Medical City

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Bay Lake

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The entrance to Aquatica with colorful signage and a water slide.

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

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A golf course with bunkers, water hazards, and a large lake.

Reunion

The top golf courses and fun-filled water parks are top of the list for many visitors to Reunion. A stop by Reunion Resort Golf Course or Jack Nicklaus Course might round out your trip.

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Florida Center

If you're spending some time in Florida Center, Universal Orlando Resort and Universal Studios Florida are top sights worth seeing.

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A large Ferris wheel with blue lighting, surrounded by a parking lot and buildings.

Champions Gate

Ample dining options and top golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

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Top Lake Nona Medical City Hotel Reviews

Hyatt Regency Orlando International Airport

10/10 Excellent

"We thoroughly enjoyed our overnight stay. The whole facility was great to explore. Rooms were quiet, cleaned really well and so guest friendly with amenities provided. Every single staff member we interacted with were friendly, helpful and professional."