What's it like in Lake Nona Medical City?

Lake Nona Medical City is a neighbourhood that travellers like for its restaurants.

What's the best accommodation in Lake Nona Medical City?

Based on Expedia customer reviews, Aloft Orlando Lake Nona is the highest ranked property in Lake Nona Medical City. This hotel offers a restaurant and an outdoor pool. Other favourite options in the area include Residence Inn Orlando Lake Nona and Courtyard Orlando Lake Nona .

How many hotels will I find in Lake Nona Medical City?

Expedia has 5 Lake Nona Medical City hotels and other accommodation options, and one might make a good home base for venturing out into the greater Orlando area.

If I need to cancel my hotel reservation in Lake Nona Medical City, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Lake Nona Medical City.

What is there to do around this Orlando neighbourhood?

Eagle Creek Golf Club, USTA National Campus and Austin-Tindall Regional Park are just a few of the places to visit in and around Lake Nona Medical City. When you're sightseeing around the area, Lake Hart and Moss Park are a couple of other sights to visit.

The Best Hotels in Lake Nona Medical City, Orlando - 2026 Updated Prices

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Our top choices for Lake Nona Medical City hotels

1. Courtyard Orlando Lake Nona

Lake Nona Medical City

William

Rp2.753.318 total

includes taxes & fees

16 Aug - 17 Aug

2. Residence Inn Orlando Lake Nona

Lake Nona Medical City

David

Rp3.410.816 total

includes taxes & fees

23 Aug - 24 Aug

3. Aloft by Marriott Orlando Lake Nona

Lake Nona Medical City

Claribel

Rp2.844.320 total

includes taxes & fees

4 Aug - 5 Aug

4. Hyatt House Orlando Airport

Airport North, 10.5 km from Lake Nona Medical City

Regina

Rp2.319.145 total

includes taxes & fees

23 Aug - 24 Aug

5. Hyatt Regency Orlando International Airport

7.7 km from Lake Nona Medical City

Corinne

Rp3.783.868 total

includes taxes & fees

10 Aug - 11 Aug

6. Hampton Inn & Suites Orlando Airport @ Gateway Village

Airport North, 10.6 km from Lake Nona Medical City

Nadina

Rp1.901.698 total

includes taxes & fees

3 Aug - 4 Aug

7. Wingate by Wyndham - Orlando International Airport

Airport North, 11.1 km from Lake Nona Medical City

Terry

Rp1.519.651 total

includes taxes & fees

3 Aug - 4 Aug

8. Wyndham Garden Orlando Airport

Belle Isle, 11.9 km from Lake Nona Medical City

Carlos

Rp1.815.646 total

includes taxes & fees

30 Jul - 31 Jul

9. Cambria Hotel Orlando Airport

11.1 km from Lake Nona Medical City

Eman

Rp2.049.311 total

includes taxes & fees

23 Aug - 24 Aug

Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility/Hearing Accessible) | Premium bedding, in-room safe, desk, blackout curtains

10. Ramada by Wyndham Suites Orlando Airport

Airport North, 10.4 km from Lake Nona Medical City

Iris

Rp1.574.576 total

includes taxes & fees

30 Jul - 31 Jul

11. Holiday Inn Express Orlando International Airport by IHG

11.1 km from Lake Nona Medical City

Turrell

Rp1.682.806 total

includes taxes & fees

11 Aug - 12 Aug

12. DoubleTree by Hilton Orlando Airport

Airport North, 11.2 km from Lake Nona Medical City

Mark

Rp2.143.116 total

includes taxes & fees

11 Aug - 12 Aug

13. Holiday Inn Orlando International Airport by IHG

Airport North, 10.8 km from Lake Nona Medical City

Edward

Rp1.727.763 total

includes taxes & fees

2 Aug - 3 Aug

14. avid hotel Orlando International Airport by IHG

11.2 km from Lake Nona Medical City

Meshia

Rp1.663.964 total

includes taxes & fees

4 Aug - 5 Aug

15. Country Inn & Suites by Radisson, Orlando Airport, FL

Airport North, 11 km from Lake Nona Medical City

Gregory

Rp1.659.304 total

includes taxes & fees

4 Aug - 5 Aug

Premium bedding, pillow-top beds, in-room safe, desk

16. Hyatt Place Orlando Airport

Airport North, 11 km from Lake Nona Medical City

Gregory

Rp1.904.139 total

includes taxes & fees

30 Jul - 31 Jul

17. Hampton Inn Orlando-International Airport

Airport North, 10.8 km from Lake Nona Medical City

Nolan

Rp1.901.699 total

includes taxes & fees

5 Aug - 6 Aug

18. La Quinta Inn & Suites by Wyndham Orlando Airport

Airport North, 10.9 km from Lake Nona Medical City

Kevin

Rp1.448.448 total

includes taxes & fees

23 Aug - 24 Aug

19. EVEN Hotel Orlando International Airport by IHG

Airport North, 11.1 km from Lake Nona Medical City

Angel Luis Rivera

Rp1.689.676 total

includes taxes & fees

17 Aug - 18 Aug

20. La Quinta Inn & Suites by Wyndham Orlando UCF

25.4 km from Lake Nona Medical City

Luisa

Rp1.810.651 total

includes taxes & fees

2 Aug - 3 Aug

View all properties

Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas for the activities you enjoy most. Learn more about Lake Nona Medical City

The entrance to the Hollywood Studios area with a large sign and distinctive architecture.

Bay Lake

Exciting theme parks plentiful wildlife and top sights from Epcot® to Walt Disney World® Resort – discover Bay Lake, a destination also famous for its entertainment.

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The entrance to Aquatica with colorful signage and a water slide.

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

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A golf course with bunkers, water hazards, and a large lake.

Reunion

The top golf courses and fun-filled water parks are top of the list for many visitors to Reunion. A stop by Reunion Resort Golf Course or Jack Nicklaus Course might round out your trip.

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A roller coaster at Universal Orlando Resort, featuring a tall palm tree and a clear blue sky.

Florida Center

If you're spending some time in Florida Center, Universal Orlando Resort and Universal Studios Florida are top sights worth seeing.

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A large Ferris wheel with blue lighting, surrounded by a parking lot and buildings.

Champions Gate

Ample dining options and top golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

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Top Lake Nona Medical City Hotel Reviews

Westgate Lakes Resort & Spa Universal Studios Area

10/10 Excellent

"Amazing trip, accommodating staff and overall perfect trip.."

Vacation Village Orlando, Celebration

10/10 Excellent

"Très bien situé à Orlando. Nous étions dans le bâtiment 19 et avons vraiment apprécié la présence du boisé autour de la piscine et la tranquillité. Seul bémol, il devait y avoir une cuisine complète et nous n’avions pas de four, seulement une plaque à cuisson comme pour le camping, mais nous nous sommes quand même débrouillés. Il manquait quelques fournitures de cuisine comme une paire de ciseaux et une fourchette pour les pâtes mais encore là rien de majeur. La suite une chambre est parfaite pour une famille avec un enfant et nous avons vraiment aimé le fait que les chambres ont un balcon. Nous reviendrons."

Sheraton Vistana Villages Resort Villas, I-Drive/Orlando

10/10 Excellent

"I am a return guest- that is how much I love to stay here. I did not appreciate such a long check in and 1 person working. We had a group of people with us (3 suites). I did not appreciate the nightly parking fee either. I also did not like that I called them to reserve my third suite and asked what the price was - to find out that booking companies offered it for a lot less. The staff checking on that said he’s give me a discount which was significantly here than the booking company. Still, we went and had a great time. I do love it there!"

Search Hotels in Lake Nona Medical City, Orlando

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Our top choices for Lake Nona Medical City hotels

1. Courtyard Orlando Lake Nona

2. Residence Inn Orlando Lake Nona

3. Aloft by Marriott Orlando Lake Nona

4. Hyatt House Orlando Airport

5. Hyatt Regency Orlando International Airport

6. Hampton Inn & Suites Orlando Airport @ Gateway Village

7. Wingate by Wyndham - Orlando International Airport

8. Wyndham Garden Orlando Airport

9. Cambria Hotel Orlando Airport

10. Ramada by Wyndham Suites Orlando Airport

11. Holiday Inn Express Orlando International Airport by IHG

12. DoubleTree by Hilton Orlando Airport

13. Holiday Inn Orlando International Airport by IHG

14. avid hotel Orlando International Airport by IHG

15. Country Inn & Suites by Radisson, Orlando Airport, FL

16. Hyatt Place Orlando Airport

17. Hampton Inn Orlando-International Airport

18. La Quinta Inn & Suites by Wyndham Orlando Airport

19. EVEN Hotel Orlando International Airport by IHG

20. La Quinta Inn & Suites by Wyndham Orlando UCF

Where to stay in Lake Nona Medical City

Bay Lake

International Drive District

Reunion

Florida Center

Champions Gate

Top Lake Nona Medical City Hotel Reviews

Westgate Lakes Resort & Spa Universal Studios Area

Frequently asked questions

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