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Check prices for these dates

Next weekend
6 Nov - 8 Nov
In two weeks
13 Nov - 15 Nov

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Our top choices for Lake Nona Medical City hotels

Exterior

1. Aloft by Marriott Orlando Lake Nona

Aloft by Marriott Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (464 reviews)
"nice clean hotel, close to restaurants"
United States
Ali
The price is Rp2.522.433
Rp2.866.113 total
includes taxes & fees
8 Nov - 9 Nov
Aloft by Marriott Orlando Lake Nona
A swimming pool with sun loungers and palm trees.

2. Courtyard Orlando Lake Nona

Courtyard Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (664 reviews)
"We had an amazing stay! Room was so nice and the perfect location! I dropped off balloons a day early to have in the room as a birthday surprise and the staff was so accommodating and nice! Shout out to Stephen who was great!"
United States
Christine
The price is Rp2.921.667
Rp3.319.721 total
includes taxes & fees
26 Nov - 27 Nov
Courtyard Orlando Lake Nona
A swimming pool with sun loungers and palm trees, surrounded by a modern building.

3. Residence Inn Orlando Lake Nona

Residence Inn Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (347 reviews)
"Hotel was very nice."
United States
Christine
The price is Rp3.264.660
Rp3.709.561 total
includes taxes & fees
25 Nov - 26 Nov
Residence Inn Orlando Lake Nona
A hotel pool area with lounge chairs and umbrellas, surrounded by tall buildings and a sunset sky.

4. Drury Plaza Hotel Orlando - Disney Springs Area

Drury Plaza Hotel Orlando - Disney Springs Area
4.0 star property
22.9 km from Lake Nona Medical City
9.8 out of 10, Exceptional, (6,201 reviews)
"Wonderful location with great amenities and an outstanding and welcoming staff."
United States
David
The price is Rp3.155.657
Rp3.550.115 total
includes taxes & fees
23 Nov - 24 Nov
Drury Plaza Hotel Orlando - Disney Springs Area
A hotel room with a bed, a sofa, a desk, a TV, and a painting on the wall.

5. Wingate by Wyndham - Orlando International Airport

Wingate by Wyndham - Orlando International Airport
3.0 star property
Airport North, 11.1 km from Lake Nona Medical City
8.8 out of 10, Excellent, (4,331 reviews)
"Stay was very pleasant"
United States
Rosacruz
The price is Rp1.551.568
Rp1.745.514 total
includes taxes & fees
2 Nov - 3 Nov
Wingate by Wyndham - Orlando International Airport
A modern lobby with a reception desk, seating area, and a green wall.

6. Holiday Inn Orlando International Drive by IHG

Holiday Inn Orlando International Drive by IHG
3.0 star property
International Drive District, 21.1 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (1,658 reviews)
"Location and hotel are great"
United States
Hector
The price is Rp1.740.660
Rp1.958.244 total
includes taxes & fees
29 Nov - 30 Nov
Holiday Inn Orlando International Drive by IHG
An outdoor patio area with seating, a bar, and a fire feature.

7. Hyatt House Orlando Airport

Hyatt House Orlando Airport
3.5 star property
Airport North, 10.5 km from Lake Nona Medical City
9.6 out of 10, Exceptional, (2,846 reviews)
"Great place to stay."
United States
CHRIS
The price is Rp2.504.286
Rp2.817.322 total
includes taxes & fees
22 Nov - 23 Nov
Hyatt House Orlando Airport
An aerial view of a resort with a large swimming pool surrounded by palm trees and lounge chairs.

8. Wyndham Grand Orlando Resort Bonnet Creek

Wyndham Grand Orlando Resort Bonnet Creek
4.0 star property
25.5 km from Lake Nona Medical City
8.8 out of 10, Excellent, (3,168 reviews)
"Great experience, will definitely stay here in the future!"
United States
Oscar
The price is Rp2.742.314
Rp3.942.077 total
includes taxes & fees
15 Nov - 16 Nov
Wyndham Grand Orlando Resort Bonnet Creek
A Holiday Inn Express building with a modern design, featuring a prominent entrance and a covered walkway.

9. Holiday Inn Express Orlando International Airport by IHG

Holiday Inn Express Orlando International Airport by IHG
2.5 star property
11.1 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (2,038 reviews)
"Wonderful 3 night stay. Very friendly staff"
United States
Andrea
The price is Rp1.778.406
Rp2.000.707 total
includes taxes & fees
1 Dec - 2 Dec
Holiday Inn Express Orlando International Airport by IHG
An outdoor seating area with green chairs and umbrellas, a fire pit, and a building with large windows in the background.

10. Hampton Inn & Suites Orlando Airport @ Gateway Village

Hampton Inn & Suites Orlando Airport @ Gateway Village
3.0 star property
Airport North, 10.6 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (2,928 reviews)
"Clean room, friendly staff, and great breakfast options"
United States
Imran
The price is Rp1.989.819
Rp2.238.547 total
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn & Suites Orlando Airport @ Gateway Village
An aerial view of a resort with a large swimming pool, sun loungers, and palm trees.

11. Caribe Royale Orlando, WorldHotels Elite

Caribe Royale Orlando, WorldHotels Elite
4.5 star property
21.4 km from Lake Nona Medical City
9.2 out of 10, Wonderful, (5,331 reviews)
"Perfect family resort."
United States
Omid
The price is Rp3.157.578
Rp4.328.060 total
includes taxes & fees
22 Nov - 23 Nov
Caribe Royale Orlando, WorldHotels Elite
An aerial view of a resort with multiple swimming pools, landscaped gardens, and outdoor seating areas.

12. Rosen Shingle Creek

Rosen Shingle Creek
4.5 star property
16.9 km from Lake Nona Medical City
9.6 out of 10, Exceptional, (4,990 reviews)
"Great staff, location, resort was amazing"
United States
Dominic
The price is Rp2.163.122
Rp2.433.512 total
includes taxes & fees
24 Nov - 25 Nov
Rosen Shingle Creek
A modern living room with a stone fireplace, a sofa, a coffee table, and a lamp.

13. Fairfield Inn By Marriott Orlando Airport

Fairfield Inn By Marriott Orlando Airport
3.5 star property
Airport North, 10.8 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (2,641 reviews)
"The staff was very friendly and breakfast was pretty good!"
United States
Eddie
The price is Rp1.527.070
Rp1.717.954 total
includes taxes & fees
29 Nov - 30 Nov
Fairfield Inn By Marriott Orlando Airport
Pool

14. Hyatt Regency Grand Cypress

Hyatt Regency Grand Cypress
4.0 star property
22.9 km from Lake Nona Medical City
9.2 out of 10, Wonderful, (2,400 reviews)
"Great hotel!"
United States
Christine
The price is Rp2.756.824
Rp4.121.633 total
includes taxes & fees
22 Nov - 23 Nov
Hyatt Regency Grand Cypress
A modern hotel lobby with a large flat-screen TV, a blue sofa, a round wooden table, and a curved reception desk.

15. Cambria Hotel Orlando Airport

Cambria Hotel Orlando Airport
3.0 star property
11.1 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (2,018 reviews)
"Loved our stay, check in was super duper easy and the bed was soo comfy!"
United States
Seth
The price is Rp1.727.594
Rp1.943.544 total
includes taxes & fees
25 Nov - 26 Nov
Cambria Hotel Orlando Airport
A hotel pool area with lounge chairs and umbrellas, surrounded by palm trees and modern buildings.

16. Universal's Endless Summer Resort - Surfside Inn and Suites

Universal's Endless Summer Resort - Surfside Inn and Suites
3.0 star property
International Drive District, 21.3 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (2,757 reviews)
"Convenient, clean, just a great place to stay"
United States
Jeff
The price is Rp2.812.785
Rp3.164.383 total
includes taxes & fees
8 Nov - 9 Nov
Universal's Endless Summer Resort - Surfside Inn and Suites
A modern dining area with a large table, chairs, and a coffee station.

17. avid hotel Orlando International Airport by IHG

avid hotel Orlando International Airport by IHG
2.5 star property
11.2 km from Lake Nona Medical City
9.2 out of 10, Wonderful, (2,180 reviews)
"Airport shuttle was nice, the hotel was very clean"
United States
Jamie
The price is Rp1.651.377
Rp1.857.798 total
includes taxes & fees
1 Dec - 2 Dec
avid hotel Orlando International Airport by IHG
A modern kitchen with a central island, bar stools, and pendant lighting.

18. Wyndham Garden Orlando Airport

Wyndham Garden Orlando Airport
3.0 star property
Belle Isle, 11.9 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (4,213 reviews)
"Excellent staff, dining options and clean property with convenient location."
United States
Linette
The price is Rp1.596.056
Rp1.795.562 total
includes taxes & fees
3 Nov - 4 Nov
Wyndham Garden Orlando Airport
A hotel lobby with a gallery wall, seating areas, and a reception desk.

19. Holiday Inn Orlando International Airport by IHG

Holiday Inn Orlando International Airport by IHG
3.5 star property
Airport North, 10.8 km from Lake Nona Medical City
8.4 out of 10, Very good, (1,541 reviews)
"Nice room and the service staff were excellent."
United States
Raul
The price is Rp1.705.818
Rp1.919.046 total
includes taxes & fees
30 Nov - 1 Dec
Holiday Inn Orlando International Airport by IHG
A modern hotel with a red carpet leading to the entrance, a wooden walkway, and a clear view of the building's facade.

20. EVEN Hotel Orlando International Airport by IHG

EVEN Hotel Orlando International Airport by IHG
3.5 star property
Airport North, 11.1 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (966 reviews)
"Good hotel"
United States
Bryan
The price is Rp1.681.320
Rp1.891.485 total
includes taxes & fees
1 Nov - 2 Nov
EVEN Hotel Orlando International Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels in Lake Nona Medical City

Exterior

Aloft by Marriott Orlando Lake Nona

3.0 star property
Lake Nona Medical City
View
A swimming pool with sun loungers and palm trees.

Courtyard Orlando Lake Nona

3.0 star property
Lake Nona Medical City
View
A swimming pool with sun loungers and palm trees, surrounded by a modern building.

Residence Inn Orlando Lake Nona

3.0 star property
Lake Nona Medical City
View
A hotel pool area with lounge chairs and umbrellas, surrounded by tall buildings and a sunset sky.

Drury Plaza Hotel Orlando - Disney Springs Area

4.0 star property
22.9 km from Lake Nona Medical City
View
A hotel room with a bed, a sofa, a desk, a TV, and a painting on the wall.

Wingate by Wyndham - Orlando International Airport

3.0 star property
Airport North, 11.1 km from Lake Nona Medical City
View
9.6
Exceptional
464 reviews
9.6
Exceptional
664 reviews
9.6
Exceptional
347 reviews
9.8
Exceptional
6,201 reviews
8.8
Excellent
4,331 reviews
The price is Rp2.522.433
Rp2.866.113 total
includes taxes & fees
8 Nov - 9 Nov
The price is Rp2.921.667
Rp3.319.721 total
includes taxes & fees
26 Nov - 27 Nov
The price is Rp3.264.660
Rp3.709.561 total
includes taxes & fees
25 Nov - 26 Nov
The price is Rp3.155.657
Rp3.550.115 total
includes taxes & fees
23 Nov - 24 Nov
The price is Rp1.551.568
Rp1.745.514 total
includes taxes & fees
2 Nov - 3 Nov
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking

Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas for the activities you enjoy most. Learn more about Lake Nona Medical City
Learn more about Lake Nona Medical City
The entrance to the Hollywood Studios area with a large sign and distinctive architecture.
Photo by Gary Burke
Open Photo by Gary Burke

Bay Lake

Exciting theme parks plentiful wildlife and top sights from Epcot® to Walt Disney World® Resort – discover Bay Lake, a destination also famous for its entertainment.

A large Ferris wheel with blue lights, surrounded by a cityscape with illuminated buildings and a tall green tower.

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

A roller coaster at Universal Orlando Resort, featuring a tall palm tree and a clear blue sky.
Photo by Peter Sutton
Open Photo by Peter Sutton

Florida Center

If you're spending some time in Florida Center, Universal Orlando Resort and Universal Studios Florida are top sights worth seeing.

A large Ferris wheel with blue lighting, surrounded by a parking lot and buildings.

Champions Gate

Ample dining options and top golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

A golf course with bunkers, water hazards, and a large lake.

Reunion

The top golf courses and fun-filled water parks are top of the list for many visitors to Reunion. A stop by Reunion Resort Golf Course or Jack Nicklaus Course might round out your trip.

Top Lake Nona Medical City Hotel Reviews

Universal's Cabana Bay Beach Resort

Universal's Cabana Bay Beach Resort

10/10 Excellent
"We have been staying at Cabana Bay for the past 3 years for HHN it is super easy to get to the park and back, buses are always running and they Bayline diner has different types of food even at 0300 when you comeback tired from the parks."
Yorika 2-night trip
Posted 2 hours ago
Universal's Cabana Bay Beach Resort

Frequently asked questions

What's it like in Lake Nona Medical City?
Lake Nona Medical City is a neighbourhood that travellers like for its restaurants.
What's the best accommodation in Lake Nona Medical City?
Based on Expedia customer reviews, Aloft Orlando Lake Nona is the highest ranked property in Lake Nona Medical City. This hotel offers a restaurant and an outdoor pool. Other favourite options in the area include Residence Inn Orlando Lake Nona and Courtyard Orlando Lake Nona.
How many hotels will I find in Lake Nona Medical City?
Expedia has 5 Lake Nona Medical City hotels and other accommodation options, and one might make a good home base for venturing out into the greater Orlando area.
If I need to cancel my hotel reservation in Lake Nona Medical City, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Lake Nona Medical City.
What is there to do around this Orlando neighbourhood?
Eagle Creek Golf Club, USTA National Campus and Austin-Tindall Regional Park are just a few of the places to visit in and around Lake Nona Medical City. When you're sightseeing around the area, Lake Hart and Kissimmee Bay Country Club are a couple of other sights to visit.