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Our top choices for Lewis and Clark Trail Trailhead hotels

Premium bedding, desk, iron/ironing board, free WiFi

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
3.2 km from Lewis and Clark Trail Trailhead
9.0 out of 10, Wonderful, (1,007 reviews)
"The room was very clean and staff very helpful."
United States
Cheryl
The price is Rp1.327.811
Rp1.566.153 total
includes taxes & fees
24 Mar - 25 Mar
Sleep Inn & Suites O'Fallon MO - Technology Drive
Exterior

Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG
2.5 star property
3.2 km from Lewis and Clark Trail Trailhead
8.6 out of 10, Excellent, (881 reviews)
"It was a wonderful stay for my girls and her birthday. She had a blast and the room was Lovely 😍🌹"
United States
Amanda
The price is Rp1.475.346
Rp1.740.172 total
includes taxes & fees
22 Mar - 23 Mar
Holiday Inn Express St. Louis West - O'Fallon by IHG
Exterior

Staybridge Suites O'Fallon Chesterfield by IHG

Staybridge Suites O'Fallon Chesterfield by IHG
3.0 star property
3.2 km from Lewis and Clark Trail Trailhead
8.6 out of 10, Excellent, (425 reviews)
"Room, staff,and breakfast was great!!"
United States
Renee
The price is Rp2.153.666
Rp2.540.249 total
includes taxes & fees
5 Apr - 6 Apr
Staybridge Suites O'Fallon Chesterfield by IHG
Lobby

Residence Inn by Marriott O'Fallon

Residence Inn by Marriott O'Fallon
3.0 star property
3.6 km from Lewis and Clark Trail Trailhead
8.4 out of 10, Very good, (467 reviews)
"Hey thank you guys we had a great time rarong 100 out of 10"
United States
Donald
The price is Rp2.221.498
Rp2.620.256 total
includes taxes & fees
3 Apr - 4 Apr
Residence Inn by Marriott O'Fallon
Property amenity

TownePlace Suites by Marriott St. Louis Chesterfield

TownePlace Suites by Marriott St. Louis Chesterfield
3.0 star property
5.8 km from Lewis and Clark Trail Trailhead
9.0 out of 10, Wonderful, (286 reviews)
"The parking was Perfect & the front desk, Amy was Absolutely Phenomenal! Very friendly, polite, warm & welcoming! "
United States
Annette
The price is Rp2.119.750
Rp2.487.802 total
includes taxes & fees
29 Mar - 30 Mar
TownePlace Suites by Marriott St. Louis Chesterfield
Standard Room, 2 Queen Beds, Non Smoking | Hypo-allergenic bedding, desk, laptop workspace, blackout curtains

Comfort Inn & Suites Chesterfield - St. Louis

Comfort Inn & Suites Chesterfield - St. Louis
2.5 star property
6.6 km from Lewis and Clark Trail Trailhead
7.8 out of 10, Good, (1,001 reviews)
"Enjoying the relaxing stay!"
United States
Naikia
The price is Rp1.427.016
Rp1.719.871 total
includes taxes & fees
22 Mar - 23 Mar
Comfort Inn & Suites Chesterfield - St. Louis
Lobby sitting area

Hilton Garden Inn St. Louis/O'Fallon MO

Hilton Garden Inn St. Louis/O'Fallon MO
3.0 star property
7.1 km from Lewis and Clark Trail Trailhead
8.8 out of 10, Excellent, (729 reviews)
"The front desk staff was outstanding. Great location for us"
United States
Timothy
The price is Rp2.003.588
Rp2.375.755 total
includes taxes & fees
29 Mar - 30 Mar
Hilton Garden Inn St. Louis/O'Fallon MO
Free daily full breakfast

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
2.5 star property
10.3 km from Lewis and Clark Trail Trailhead
9.0 out of 10, Wonderful, (1,002 reviews)
"This property is currently under some remodeling, but it is being updated nicely! The staff is very accommodating and friendly. And there is so much to do in this area! We really enjoyed our stay."
United States
Julie
The price is Rp2.136.708
Rp2.486.338 total
includes taxes & fees
5 Apr - 6 Apr
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
Courtyard

Hampton Inn & Suites St. Louis/Chesterfield

Hampton Inn & Suites St. Louis/Chesterfield
3.5 star property
10.9 km from Lewis and Clark Trail Trailhead
8.8 out of 10, Excellent, (861 reviews)
"Great location, free breakfast "
United States
Lynn
The price is Rp1.807.723
Rp2.103.520 total
includes taxes & fees
5 Apr - 6 Apr
Hampton Inn & Suites St. Louis/Chesterfield
BBQ/picnic Area

Courtyard by Marriott St. Louis Chesterfield

Courtyard by Marriott St. Louis Chesterfield
3.0 star property
10.9 km from Lewis and Clark Trail Trailhead
9.0 out of 10, Wonderful, (603 reviews)
"Nice hotel. Clean and comfortable rooms. "
United States
David
The price is Rp1.967.128
Rp2.289.009 total
includes taxes & fees
2 Apr - 3 Apr
Courtyard by Marriott St. Louis Chesterfield
Lobby

Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
3.0 star property
14.8 km from Lewis and Clark Trail Trailhead
9.8 out of 10, Exceptional, (1,101 reviews)
"It’s a great place very happy!"
United States
Chris
The price is Rp2.204.370
Rp2.556.805 total
includes taxes & fees
3 Apr - 4 Apr
Drury Plaza Hotel St. Louis Chesterfield
Property entrance

The Wildwood Hotel

The Wildwood Hotel
3.5 star property
14.7 km from Lewis and Clark Trail Trailhead
9.2 out of 10, Wonderful, (1,631 reviews)
"Great space for a couple "
United States
John
The price is Rp1.587.269
Rp1.849.100 total
includes taxes & fees
15 Apr - 16 Apr
The Wildwood Hotel
Room, Accessible | Desk, iron/ironing board, free WiFi, bed sheets

Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area
2.0 star property
12.5 km from Lewis and Clark Trail Trailhead
6.8 out of 10, (1,000 reviews)
"Staff was awesome and accomodating. Room and price was great. "
United States
Anthony
The price is Rp1.167.558
Rp1.377.135 total
includes taxes & fees
22 Mar - 23 Mar
Super 8 by Wyndham O'Fallon MO/St. Louis Area
Property amenity

Residence Inn by Marriott St. Louis Chesterfield

Residence Inn by Marriott St. Louis Chesterfield
3.0 star property
12.4 km from Lewis and Clark Trail Trailhead
9.6 out of 10, Exceptional, (209 reviews)
"Room was clean and the property was well maintained. I wish there had been an extra pillow or two in the closet and the doors shut more quietly."
United States
Christina
The price is Rp3.205.062
Rp3.749.539 total
includes taxes & fees
22 Mar - 23 Mar
Residence Inn by Marriott St. Louis Chesterfield
Lobby

Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
15 km from Lewis and Clark Trail Trailhead
9.4 out of 10, Exceptional, (1,004 reviews)
"Greatest stay ever "
United States
Eddie
The price is Rp1.865.210
Rp2.144.057 total
includes taxes & fees
22 Mar - 23 Mar
Drury Inn & Suites St. Louis St. Peters
Cleanliness standards

Relax Inn Saint Charles

Relax Inn Saint Charles
2.0 star property
18.2 km from Lewis and Clark Trail Trailhead
6.8 out of 10, (1,003 reviews)
"Cozy and retro"
United States
Erin
The price is Rp1.068.354
Rp1.227.759 total
includes taxes & fees
17 Mar - 18 Mar
Relax Inn Saint Charles
Bar (on property)

Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield
3.0 star property
14.9 km from Lewis and Clark Trail Trailhead
9.6 out of 10, Exceptional, (1,003 reviews)
"Clean rooms, quiet area. Check in easy, breakfast good! "
United States
Jamie
The price is Rp2.136.708
Rp2.478.325 total
includes taxes & fees
5 Apr - 6 Apr
Hyatt Place St. Louis/Chesterfield
Exterior

Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG
2.5 star property
13.4 km from Lewis and Clark Trail Trailhead
9.4 out of 10, Exceptional, (396 reviews)
"Very clean room, great guest service, excellent bed "
United States
Margaret
The price is Rp1.882.338
Rp2.267.361 total
includes taxes & fees
29 Mar - 30 Mar
Holiday Inn Express & Suites St Peters by IHG
Lobby

Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles
2.0 star property
13.7 km from Lewis and Clark Trail Trailhead
6.2 out of 10, (1,001 reviews)
"Room was excellent and clean"
United States
catherine
The price is Rp1.153.144
Rp1.325.539 total
includes taxes & fees
5 Apr - 6 Apr
Days Inn by Wyndham St Peters/St Charles
Interior

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
16.1 km from Lewis and Clark Trail Trailhead
6.4 out of 10, (520 reviews)
"Really cozy place to stay at!"
United States
Yufei
The price is Rp1.017.480
Rp1.154.331 total
includes taxes & fees
18 Mar - 19 Mar
Economy Inn Wentzville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Lewis and Clark Trail Trailhead Hotel Reviews

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

10/10 Excellent
"Room was clean and very nice! Casino was nice. We didn’t use the spa or weight room."
Erica 2-night trip
Posted 2 hours ago
Ameristar Casino Resort and Spa

Hotels near other Lewis and Clark Trail Trailhead attractions

Wetlands landscape with a bird blind and cloudy sky reflected in a lake at the August A. Busch Memorial Conservation Area in St. Charles County Missouri

August A. Busch Memorial Conservation Area

Explore the great outdoors at August A. Busch Memorial Conservation Area, a lovely green space in Defiance. While in this family-friendly area, you can savour the top-notch restaurants.
See properties
9-11 memorial in New York

9-11 Memorial

3.9/5 (30 reviews)
Learn about the local history of O'Fallon when you spend time at 9-11 Memorial. While in this family-friendly area, you can savour the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Lewis and Clark Trail Trailhead?
Lewis and Clark Trail Trailhead is located in Weldon Spring Heights. You'll find 27 hotels and other accommodations within a few miles for a convenient home base.
What's the best hotel to stay close to Lewis and Clark Trail Trailhead?
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. You'll find it 6.4 mi (10.3 km) from Lewis and Clark Trail Trailhead. Other good options around the area include The Wildwood Hotel and Drury Plaza Hotel St. Louis Chesterfield.
How many hotels can I expect to find near Lewis and Clark Trail Trailhead?
Expedia has 27 hotels and other accommodation options a few miles from Lewis and Clark Trail Trailhead.
If I need to cancel the hotel reservation for my stay near Lewis and Clark Trail Trailhead, will I receive a refund?
Yes, most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to get the best options available near Lewis and Clark Trail Trailhead.
What can I see and do near Lewis and Clark Trail Trailhead?
Explore nature at August A. Busch Memorial Conservation Area and Hamburg Trail Trailhead. Missouri Bluffs Golf Course, Babler State Park and Golf Headquarters are worth a stop while you're in the area. St. Louis Premium Outlets and Weldon Spring Site Interpretive Center are both worth a visit while you're out exploring.