The entrance to the Kentucky Science Center with a large circular structure in the foreground.

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Check prices for these dates

Tonight
21 Oct - 22 Oct
Tomorrow
22 Oct - 23 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

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Our top choices for Louisville Science Center hotels

A grand staircase with a wooden handrail and carpeted steps, leading to an upper floor.
A spacious dining area with a chandelier, a fireplace, and a view of greenery outside.
A covered outdoor seating area with wicker furniture and a wooden railing.
A living room with a sofa, armchair, coffee table, fireplace, and large windows.

1. Louisville Bourbon Inn

Louisville Bourbon Inn
Old Louisville, 2.9 km from Louisville Science Center
United States
Roy
Rp5.019.768
Rp5.826.445 total
includes taxes & fees
1 Nov - 2 Nov
Louisville Bourbon Inn
A wooden staircase with a balustrade leading to a landing.
A bedroom with a bed, a dresser, a television, and a desk with a lamp.
A brick building with a covered porch, columns, and potted plants.
A dining area with brick walls, wooden shelves, and tables set for a meal.

2. Market Street Inn

Market Street Inn
2.1 km from Louisville Science Center
United States
Holly
Rp3.978.571
Rp4.495.841 total
includes taxes & fees
25 Oct - 26 Oct
Market Street Inn
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.
A living room with a sofa, a fireplace, a staircase, and a chandelier.
A room with a red velvet sofa, a blue armchair, and a small round table with books.
An outdoor patio with red furniture, including a table and chairs, and two red umbrellas providing shade.

3. DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
Old Louisville, 2.8 km from Louisville Science Center
United States
Casey
Rp2.932.295
Rp3.403.476 total
includes taxes & fees
16 Nov - 17 Nov
DuPont Mansion Bed & Breakfast
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.
An outdoor dining area with tables and chairs, a green building facade, and a row of plants along the wall.
A modern living room with a leather sectional sofa, a glass coffee table, and a view of the city skyline through large windows.

4. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
Downtown Louisville, 0.9 km from Louisville Science Center
United States
Heather
Rp4.113.044
Rp4.839.407 total
includes taxes & fees
8 Nov - 9 Nov
Hotel Distil, Autograph Collection
A grand lobby with ornate columns, plush seating, and a chandelier.
A grand lobby with ornate ceiling and chandeliers, a large vase, and a seating area with multiple sofas and armchairs.
A grand lobby with ornate ceiling, large windows, and classic furniture.
A grand lobby with ornate ceiling, multiple seating areas, and a staircase.

5. The Brown Hotel

The Brown Hotel
Downtown Louisville, 1.2 km from Louisville Science Center
United States
John
Rp2.576.454
Rp3.031.455 total
includes taxes & fees
15 Nov - 16 Nov
The Brown Hotel
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
A building with a sign reading "THE GRADY" at the entrance.
A multi-level interior with a staircase, bookshelves, and a prominent sign reading "THE GRADY".
A modern restaurant interior with a staircase, round tables, and a brick wall.

6. The Grady

The Grady
Downtown Louisville, 0.2 km from Louisville Science Center
United States
Donna
Rp2.802.161
Rp3.297.022 total
includes taxes & fees
15 Nov - 16 Nov
The Grady
An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.
A modern hotel lobby with a brick wall, grey sofas, a coffee table, and a large TV screen displaying "TEMPO by Hilton".
A modern hotel lobby with a reception desk, seating area, and a large abstract ceiling artwork.
A modern hotel room with a large bed, a desk with a chair, a flat-screen TV, and a large window offering a city view.

7. Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
Phoenix Hill, 2.1 km from Louisville Science Center
United States
Addison
Rp2.139.249
Rp2.517.039 total
includes taxes & fees
29 Oct - 30 Oct
Tempo By Hilton Louisville Downtown Nulu
A classical gold statue in front of a multi-story building with large windows and a brick facade.
A restaurant with multiple dining tables, a long bench seating area, and framed artwork on the walls.
A steam fountain in a brick alleyway.
A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.

8. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville, < 0.1 km from Louisville Science Center
United States
Matt
Rp2.890.415
Rp3.490.824 total
includes taxes & fees
15 Nov - 16 Nov
21c Museum Hotel Louisville
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A modern interior with a fireplace, bookshelves, and seating areas.
A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.
A lobby with a marble floor, a reception desk, and a large chandelier.

9. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville, 0.8 km from Louisville Science Center
United States
Kristan
Rp3.655.974
Rp4.301.618 total
includes taxes & fees
16 Nov - 17 Nov
Omni Louisville Hotel
An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.
A modern lobby with a central reception desk, seating area, and a large abstract wall art piece.
A modern living room with a sofa, a coffee table, a side table with a plant, and a view of a building with a clock tower.

10. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Downtown Louisville, 0.8 km from Louisville Science Center
United States
Cameron
Rp2.791.639
Rp3.284.641 total
includes taxes & fees
9 Nov - 10 Nov
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
An outdoor seating area with wicker furniture and a fire pit.
A modern hotel lobby with a large central table, multiple seating areas, and large windows offering city views.
A modern lounge area with seating, tables, and a view of the city through large windows.
An indoor swimming pool with clear water, a diving board, and lounge chairs around the pool area.

11. Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
Downtown Louisville, 0.3 km from Louisville Science Center
United States
Derek
Rp1.745.224
Rp2.053.430 total
includes taxes & fees
8 Nov - 9 Nov
Towneplace Suites By Marriott Louisville Downtown
A modern bar area with a circular bar, multiple seating options, and a large screen.
A modern interior with a central wooden table, refrigerated beverage dispensers, and shelves stocked with snacks and condiments.
A modern living room with a sectional sofa, a small table, and a floor lamp. Large windows offer a view of a cityscape and a building with glass windows.
A spacious indoor area with a large dining table, multiple chairs, a fireplace, and a kitchen area with a bar.

12. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
Downtown Louisville, 1.2 km from Louisville Science Center
United States
Sarah
Rp1.856.774
Rp2.184.680 total
includes taxes & fees
15 Nov - 16 Nov
Cambria Hotel Louisville Downtown-Whiskey Row
A covered patio with a stone wall, a glass table, and a bench.
A stone house with a balcony, a front door, and a staircase leading to the entrance.
Staircase
A grand room with a fireplace, a staircase, and a chandelier.

13. Central Park Bed & Breakfast

Central Park Bed & Breakfast
Old Louisville, 3 km from Louisville Science Center
United States
Nicole
Rp3.072.494
Rp3.566.374 total
includes taxes & fees
2 Nov - 3 Nov
Central Park Bed & Breakfast
An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.
A modern bar area with sofas, tables, and a bar stocked with bottles.
A modern lounge area with a pool table, comfortable seating, a fireplace, and a brick accent wall.
A modern hotel with a prominent 'Aloft Hotels' sign, multiple floors, and a corner location with a view of the city skyline.

14. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
Downtown Louisville, 0.9 km from Louisville Science Center
United States
Anthony
Rp2.359.291
Rp2.775.941 total
includes taxes & fees
15 Nov - 16 Nov
Aloft by Marriott Louisville Downtown
A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.
A modern hotel with a prominent 'Marriott' sign, large windows, and a brick facade.
A modern hotel room with a large bed, a desk with a chair, a TV mounted on the wall, and a window with a city view.
A cozy living room with a fireplace, a black leather sofa, and a patterned rug.

15. Moxy Louisville Downtown

Moxy Louisville Downtown
Downtown Louisville, 0.9 km from Louisville Science Center
United States
Alicia
Rp2.159.040
Rp2.540.326 total
includes taxes & fees
15 Nov - 16 Nov
Moxy Louisville Downtown
Bar (on property)
A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.
A bedroom with a bed, a chair, a TV, and a window with curtains.
A bar area with a wooden bar counter, two stools, a chandelier, and a mirror.

16. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
East Market District, 2.1 km from Louisville Science Center
United States
Tyler
Rp2.428.920
Rp2.857.867 total
includes taxes & fees
31 Oct - 1 Nov
Hotel Genevieve part of JdV by Hyatt
A modern bar area with a marble countertop, seating, and a central bar stocked with bottles.
A modern hotel building with a prominent AC Hotel NULU sign, multiple floors, and a well-lit entrance.
A modern interior with a central seating area, a television screen, and a wooden partition with various items displayed.
A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.

17. AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
East Market District, 2.1 km from Louisville Science Center
United States
Jen
Rp2.574.655
Rp3.029.338 total
includes taxes & fees
31 Oct - 1 Nov
AC Hotel Louisville Downtown
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.
A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.
A balcony with a view of a river, a bridge, and a cityscape.

18. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville, 0.5 km from Louisville Science Center
United States
Judy
Rp2.530.230
Rp2.977.069 total
includes taxes & fees
8 Nov - 9 Nov
Galt House Hotel Trademark Collection by Wyndham
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.
An indoor swimming pool with clear water, surrounded by white marble walls and columns, and furnished with lounge chairs and tables.
A modern bar area with a long counter, multiple chairs, and a bookshelf filled with bottles.
A hotel dining area with long tables, booths, and a bar.

19. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
Downtown Louisville, 0.8 km from Louisville Science Center
United States
Frances
Rp2.352.837
Rp2.768.349 total
includes taxes & fees
15 Nov - 16 Nov
Embassy Suites Louisville Downtown
A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.
A reception area with marble counters, modern pendant lighting, and potted orchids.
A modern bar area with glass partitions, bar stools, and a variety of bottles.
A modern hotel room with a large window offering a city view, a cozy seating area with a sofa and chairs, a dining table with lamps, and a wooden floor.

20. Louisville Marriott Downtown

Louisville Marriott Downtown
Downtown Louisville, 0.8 km from Louisville Science Center
United States
Ricardo
Rp3.553.979
Rp4.181.611 total
includes taxes & fees
8 Nov - 9 Nov
Louisville Marriott Downtown
View all properties

Compare popular hotels close to Louisville Science Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A grand staircase with a wooden handrail and carpeted steps, leading to an upper floor.
Louisville Bourbon Inn
10.0
Exceptional
25 reviews
View
A wooden staircase with a balustrade leading to a landing.
Market Street Inn
9.8
Exceptional
125 reviews
View
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.
DuPont Mansion Bed & Breakfast
9.6
Exceptional
150 reviews
View
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
Hotel Distil, Autograph Collection
9.6
Exceptional
511 reviews
View
A grand lobby with ornate columns, plush seating, and a chandelier.
The Brown Hotel
9.4
Exceptional
1,402 reviews
View

Top Louisville Science Center Hotel Reviews

Omni Louisville Hotel

Omni Louisville Hotel

8/10 Good
"Good"
Nicole 1-night trip
Posted 6 hours ago
Omni Louisville Hotel
21c Museum Hotel Louisville

21c Museum Hotel Louisville

10/10 Excellent
"If you love ORIGINALITY this is the place!!! We absolutely loved our stay …. funky, innovative and simply refreshing. The inspiring art is an absolute treat. Great taste and finally not another copycat hotel. AND the service was excellent, bed super comfortable, lovely bathroom and we couldn’t have been happier. If you haven’t tried it. It’s an absolute must!!!"
Petra 1-night trip
Posted 6 hours ago
21c Museum Hotel Louisville
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

10/10 Excellent
"Easy quick check in.excellent location of room to event.ease of check in and check out."
Jackie 2-night trip
Posted 6 hours ago
Galt House Hotel Trademark Collection by Wyndham
Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown

8/10 Good
"Traveled with a partner for a long weekend. Location is great for Whisky Row and a lot of walkable things to do. Parking is across the street in garage $35 a day. The bathrooms have a shower only and toilet in one room. Sink, mirror and small counter top. The shower has good water pressure, but nowhere to put a razor, wash cloth. No where to prop your foot to shave. Towel s are hard to reach, beds are comfyand blackout curtains are wonderful"
Chloe 4-night trip
Posted 9 hours ago
Aloft by Marriott Louisville Downtown
Holiday Inn Louisville Downtown by IHG

Holiday Inn Louisville Downtown by IHG

10/10 Excellent
"Very clean, modern facility for a quick overnight. I did not use many of the amenities due to the shortness of my stay. Staff was very friendly and helpful."
Edward 1-night trip
Posted 10 hours ago
Holiday Inn Louisville Downtown by IHG
Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG

8/10 Good
"Loved the area and the staff"
evelyn 1-night trip
Posted 11 hours ago
Holiday Inn Express & Suites Louisville Downtown by IHG
Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY

10/10 Excellent
"A five star hotel with a three star budget. This place was wonderful in all ways. So thankful to have found them"
Mark 3-night trip
Posted 12 hours ago
Homewood Suites by Hilton Louisville Downtown, KY
Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown

10/10 Excellent
"déjeuner hors pair en plus de l'endroit propre et agréable"
Denise 2-night trip
Posted 13 hours ago
Towneplace Suites By Marriott Louisville Downtown
Courtyard by Marriott Louisville Downtown

Courtyard by Marriott Louisville Downtown

8/10 Good
"The hotel room was clean and spacious. Nice big TV. Road noise was a bit much late at night, but the white noise machine and ear plugs helped."
Robin 1-night trip
Posted 13 hours ago
Courtyard by Marriott Louisville Downtown

Other attractions near Louisville Science Center

A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

Louisville Slugger Museum

9.2/10 (2,299 reviews)
Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.
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A modern building with a cylindrical structure and a glass facade.

Muhammad Ali Center

8.8/10 (295 reviews)
One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.
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The Frazier History Museum with red doors and a tree in front.

Frazier International History Museum

9.4/10 (10 reviews)
Get to know Louisville with a visit to this esteemed museum. It’s a great spot for social interaction as well.
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The Kentucky Center for the Performing Arts building facade with large glass windows and a prominent sign.

Kentucky Center for the Performing Arts

8.8/10 (49 reviews)
Enjoy a pleasant night at the opera or attend a concert, live dance or stage production at this glass-fronted venue in downtown Louisville.
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Kentucky Museum of Art and Craft

You can spend an afternoon exploring the galleries in Kentucky Museum of Art and Craft during your trip to Louisville. Stroll along the area's riverfront or experience its lively festivals.
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Golden Statue of David

Find out about the history of Louisville when you spend time at Golden Statue of David. Attend a sporting event or simply enjoy the lively bars while you're in the area.
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SAR Genealogical Research Library: NSSAR Library

You can spend time exploring the galleries in SAR Genealogical Research Library: NSSAR Library in Louisville. Amble around this family-friendly area's riverfront and enjoy its top-notch restaurants.
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Louisville Glassworks

You can spend an afternoon browsing the exhibits at Louisville Glassworks in Louisville. Experience the area's lively festivals or attend a sporting event.
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Frequently asked questions

What's the area like around Louisville Science Center?
Louisville Science Center is located in an area of Louisville known for its stunning river views, sporting events and great live music scene. If you're looking for a convenient place to stay, take a look at the 292 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Louisville Science Center?
Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a 24-hour fitness centre. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.
How many hotels can I expect to find close to Louisville Science Center?
Expedia has 292 hotels and other accommodation options within a mile from Louisville Science Center.
If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?
Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer near Louisville Science Center.
What can I see and do near Louisville Science Center?
21c Museum Hotel, Louisville Slugger Museum and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row and Big Four Bridge. You can catch a show at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall.