A coastal town with terracotta-roofed houses, a beach, and a castle on a hill.

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Check availability on Mytilene Luxury Hotels

Tonight
28 Sept - 29 Sept
Tomorrow
29 Sept - 30 Sept
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Our top choices for Mytilene luxury hotels

A buffet with various food items including fruits, vegetables, and desserts.
A multi-story hotel with balconies, a central staircase, and a well-lit entrance.
A hotel room with a large bed, a desk, a chair, a small refrigerator, a staircase, and a nightstand with a lamp.
A multi-story hotel with a central courtyard, balconies, and a rooftop terrace.

1. Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel
Lesvos
  • Luxuriate in this Lesvos boutique haven where pillowtop beds meet spa indulgences, all within steps of the beach and local art.
Rp2.237.187
Rp2.654.656 total
includes taxes & fees
4 Oct - 5 Oct
Theofilos Paradise Boutique Hotel
A resort with a pool, outdoor seating, and a view of the sea at dusk.
A dining area with a table and chairs, a vase with a flower, and a view of the sea through large windows.
A spacious living room with a large window, a sofa, a coffee table, and a dining area with chairs and a table.
A modern hotel room with a large bed, a desk, and a view of the ocean.

2. Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat
Lesvos
  • Seaside luxury awaits at this Greek retreat, where beachfront bliss meets wellness indulgence with 3 indoor pools and a full-service spa.
Rp1.667.153
Rp2.132.177 total
includes taxes & fees
1 Oct - 2 Oct
Mythical Coast Wellness Retreat
A pathway flanked by lush greenery and palm trees, leading to a distant structure.
A room with a view of the sea through a window with white curtains. There is a small table with a decorative item on it.
A swimming pool with a stone building and outdoor seating area.
A stone building with a central staircase, surrounded by palm trees and a cobblestone driveway.

3. Loriet Hotel

Loriet Hotel
Lesvos
Rp1.865.610
Rp2.247.612 total
includes taxes & fees
1 Oct - 2 Oct
Loriet Hotel
A swimming pool with tiled flooring, lounge chairs, and a bar area.
A spacious outdoor lounge area with a grand piano, comfortable seating, and large windows offering a view of the pool and night lights.
A modern hotel room with a large bed, bedside table, desk, and chair.
An outdoor bar area with a pool view, wooden deck, and bar stools.

4. Heliotrope Hotels

Heliotrope Hotels
Lesvos
Rp1.558.166
Rp1.910.823 total
includes taxes & fees
1 Oct - 2 Oct
Heliotrope Hotels
A person standing on a balcony overlooking a pool and a modern building with a clear view of the sea.
A modern bar area with seating and a bar counter.
A person standing by a glass railing, holding a cup, with a view of the sea and mountains in the background.
A modern hotel with a swimming pool, outdoor seating, and a view of the sea.

5. Elysion Hotel

Elysion Hotel
Lesvos
  • Experience tranquil luxury and refined comfort at this 5-star seaside retreat with outdoor tennis courts and multiple dining options.
Rp1.991.415
Rp2.997.216 total
includes taxes & fees
3 Oct - 4 Oct
Elysion Hotel
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Top Mytilene Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your Mytilene holiday?
Mytilene has some interesting things to see and do including Port of Mytilene and Mytilini Castle, so you might want to take in the local sights during your visit.
What's the best luxury hotel in Mytilene?
Elysion Hotel is a luxury hotel with 2 restaurants and 2 bars, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Mythical Coast Wellness Retreat and Theofilos Paradise Boutique Hotel are two other upscale options for your stay.
When can I expect good weather in Mytilene?
Planning for the weather is a good way to make your trip to Mytilene relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July, with an average temperature of 25°C, while the coldest months are January and February, with an average of 11°C. Average annual precipitation for Mytilene is 873 mm.
What's there to see and do in Mytilene?
Take in the sights and attractions that Mytilene offers with a visit to Port of Mytilene, Mytilini Castle and Roman Aqueduct at Moria. If you have a little extra time during your trip, you might want to make a stop at Thermes Gera Hot Springs and St Hermogenes Charamida Lesvos.