New Madrid Holidays
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to Rp173.195 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top hotels in New Madrid
Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is Rp1.818.252 per night from 16 May to 17 May
Rp1.818.252
Rp2.058.715 total
16 May - 17 May
includes taxes & fees
9/10 Wonderful! (538 reviews)
You walk in to a fresh & clean smell, that you can’t help but notice! Vibrant & comfy colors, very friendly staff who greet you with a smile, the check-in was took maybe 2 minutes. They had breakfast 6a-10a with a variety of choices. I
Reviewed on 15 Apr 2026
Holiday Inn Express & Suites Sikeston Southwest by IHG
115 Hospitality Dr Sikeston MO
Fully refundable
The price is Rp1.736.089 per night from 3 May to 4 May
Rp1.736.089
Rp1.965.686 total
3 May - 4 May
includes taxes & fees
8.6/10 Excellent! (459 reviews)
The room was clean, beds were comfortable. Breakfast was very good with a nice selection of choices.
Reviewed on 15 Apr 2026
Fairfield Inn & Suites by Marriott Sikeston
1239 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is Rp2.028.302 per night from 15 May to 16 May
Rp2.028.302
Rp2.296.545 total
15 May - 16 May
includes taxes & fees
9.4/10 Exceptional! (72 reviews)
The breakfast was good, the service was good, and the staff was very friendly
Reviewed on 12 Apr 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
New Madrid Historical Museum
You can study the exhibits at New Madrid Historical Museum, a museum with a storied past, during your travels to New Madrid. Amble around the area's parks or experience its museums.
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
