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Top Trending Hotels Near Museum of Life and Science

Lobby
Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85

2.5 star property
1.4 km from Museum of Life and Science
9.0 out of 10, Wonderful, (1012)
"Nice place to stay and close to everything. "
United States
Christy
The price is Rp1.719.622
Rp1.951.737 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hampton Inn & Suites Durham/North I-85
Free buffet breakfast
Holiday Inn Express Durham by IHG

Holiday Inn Express Durham by IHG

2.5 star property
2.2 km from Museum of Life and Science
8.8 out of 10, Excellent, (944)
"Love my stay , great staff"
United States
Oscar
The price is Rp1.587.460
Rp1.801.766 total
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Express Durham by IHG
Lobby
Red Roof Inn Durham - Duke Univ Medical Center

Red Roof Inn Durham - Duke Univ Medical Center

2.0 star property
2.2 km from Museum of Life and Science
6.8 out of 10, (1005)
"Good motel...clean, easy acess "
United States
Howard
The price is Rp967.137
Rp1.126.070 total
includes taxes & fees
21 Dec - 22 Dec
Red Roof Inn Durham - Duke Univ Medical Center
Premium bedding, desk, blackout curtains, iron/ironing board
Comfort Inn & Suites Durham near Duke University

Comfort Inn & Suites Durham near Duke University

2.5 star property
Croasdaile Farm Master, 3.2 km from Museum of Life and Science
8.6 out of 10, Excellent, (1012)
"Loved our stay"
United States
Brian
The price is Rp1.498.504
Rp1.700.802 total
includes taxes & fees
28 Dec - 29 Dec
Comfort Inn & Suites Durham near Duke University
Miscellaneous
Super 8 by Wyndham Durham/University Area NC

Super 8 by Wyndham Durham/University Area NC

2.0 star property
2.1 km from Museum of Life and Science
5.0 out of 10, (344)
"The environment was not pleasant "
United States
Denise
The price is Rp1.062.266
Rp1.205.672 total
includes taxes & fees
3 Dec - 4 Dec
Super 8 by Wyndham Durham/University Area NC
Apartment | 3 bedrooms
Walk to Duke Campus 3 Bedroom in Trinity Park

Walk to Duke Campus 3 Bedroom in Trinity Park

2.0 star property
Trinity Park, 2.9 km from Museum of Life and Science
The price is Rp1.300.815
Rp3.518.974 total
includes taxes & fees
7 Dec - 8 Dec
Walk to Duke Campus 3 Bedroom in Trinity Park
Apartment | 2 bedrooms
Renovated 2 Bed Walltown Home Walk to Duke A

Renovated 2 Bed Walltown Home Walk to Duke A

2.0 star property
2.2 km from Museum of Life and Science
The price is Rp1.100.639
Rp2.985.392 total
includes taxes & fees
8 Dec - 9 Dec
Renovated 2 Bed Walltown Home Walk to Duke A
Courtyard
Residence Inn Durham McPherson/Duke University Medical Cntr

Residence Inn Durham McPherson/Duke University Medical Cntr

3.0 star property
Trinity Park, 3.3 km from Museum of Life and Science
9.2 out of 10, Wonderful, (458)
"Hotel was great - very friendly staff."
United States
Lisa
The price is Rp1.915.582
Rp2.174.185 total
includes taxes & fees
2 Jan - 3 Jan 2026
Residence Inn Durham McPherson/Duke University Medical Cntr
Meeting facility
Hilton Garden Inn Durham/University Medical Center

Hilton Garden Inn Durham/University Medical Center

3.0 star property
9th Street District, 3.4 km from Museum of Life and Science
9.2 out of 10, Wonderful, (1007)
"Clean rooms, nice staff. Clean hotel. Ample parking. "
United States
Emana
The price is Rp2.040.051
Rp2.315.459 total
includes taxes & fees
19 Dec - 20 Dec
Hilton Garden Inn Durham/University Medical Center
BBQ/picnic Area
Courtyard Durham Near Duke University/Downtown

Courtyard Durham Near Duke University/Downtown

3.0 star property
Croasdaile Farm Master, 3.3 km from Museum of Life and Science
8.2 out of 10, Very good, (1011)
"Staff was wonderful, hotel clean, & location was perfect!"
United States
Gena
The price is Rp1.757.545
Rp1.994.814 total
includes taxes & fees
7 Dec - 8 Dec
Courtyard Durham Near Duke University/Downtown
Outdoor pool
Royal Inn

Royal Inn

2.0 star property
4.4 km from Museum of Life and Science
5.8 out of 10, (1030)
"Awful “hotel”"
United Kingdom
Andrew
The price is Rp1.332.873
Rp1.512.810 total
includes taxes & fees
10 Dec - 11 Dec
Royal Inn
Exterior
SureStay Plus Hotel by Best Western Durham Medical Center

SureStay Plus Hotel by Best Western Durham Medical Center

2.5 star property
5.1 km from Museum of Life and Science
5.8 out of 10, (1001)
"Staff was nice & breakfast was good."
United States
Zelma
The price is Rp1.109.756
Rp1.259.572 total
includes taxes & fees
9 Dec - 10 Dec
SureStay Plus Hotel by Best Western Durham Medical Center
Premium bedding, desk, blackout curtains, iron/ironing board
The Durham Hotel

The Durham Hotel

4.0 star property
Downtown Durham, 3.6 km from Museum of Life and Science
9.0 out of 10, Wonderful, (635)
"Perfect place to stay for an easy walk to see a show at the charming Carolina Theater. Food, service and atmosphere were outstanding. "
United States
Jo
The price is Rp3.099.485
Rp3.517.916 total
includes taxes & fees
7 Dec - 8 Dec
The Durham Hotel
Daily cooked-to-order breakfast (USD 19.95 per person)
Durham Marriott City Center

Durham Marriott City Center

3.5 star property
Downtown Durham, 3.6 km from Museum of Life and Science
8.8 out of 10, Excellent, (821)
"The room was clean. The staff was very helpful and the food was good. "
United States
Tia
The price is Rp2.110.369
Rp2.395.268 total
includes taxes & fees
16 Dec - 17 Dec
Durham Marriott City Center
Exterior
Unscripted Durham, Part of JDV by Hyatt

Unscripted Durham, Part of JDV by Hyatt

3.5 star property
Downtown Durham, 3.7 km from Museum of Life and Science
8.2 out of 10, Very good, (1007)
"Staff was nice, room was large and very clean, location was excellent"
United States
Janice
The price is Rp2.116.201
Rp2.685.326 total
includes taxes & fees
16 Dec - 17 Dec
Unscripted Durham, Part of JDV by Hyatt
Interior entrance
21c Museum Hotel Durham

21c Museum Hotel Durham

4.0 star property
Downtown Durham, 3.7 km from Museum of Life and Science
8.4 out of 10, Very good, (1014)
"Overall good hotel and friendly staff. Building and rooms show some age but that is part of the charm. Enjoyable stay. "
United States
Lisa H
The price is Rp2.684.409
Rp3.130.119 total
includes taxes & fees
16 Dec - 17 Dec
21c Museum Hotel Durham
Front of property – evening/night
University Inn Durham next to Duke University Medical Center

University Inn Durham next to Duke University Medical Center

2.0 star property
4 km from Museum of Life and Science
8.8 out of 10, Excellent, (1010)
"Courteous staff, clean room"
United States
Bruce
The price is Rp1.785.892
Rp2.026.988 total
includes taxes & fees
24 Dec - 25 Dec
University Inn Durham next to Duke University Medical Center
Property amenity
Aloft Durham Downtown

Aloft Durham Downtown

3.0 star property
American Tobacco District, 4.1 km from Museum of Life and Science
9.0 out of 10, Wonderful, (730)
"Very friendly staff, very clean and convenient location"
United States
Robert
The price is Rp3.101.550
Rp3.520.260 total
includes taxes & fees
21 Dec - 22 Dec
Aloft Durham Downtown
Desk, iron/ironing board, free WiFi, bed sheets
Extended Stay America Suites Durham University

Extended Stay America Suites Durham University

2.5 star property
8.3 km from Museum of Life and Science
5.0 out of 10, (818)
"I would not recommend this place unless you are on a really tight budget. The only nice thing about it was the kind person who checked us in. The room was dingy and smelled faintly of smoke. The smoke alarm was chirping and I had to borrow tools to disconnect it so we could sleep. There was constant noise throughout the night from other guests, and the whole place smelled like weed."
United States
Derek
The price is Rp1.253.574
Rp1.422.806 total
includes taxes & fees
16 Dec - 17 Dec
Extended Stay America Suites Durham University
Front of property
The Lodge at Duke Medical Center

The Lodge at Duke Medical Center

3.0 star property
4 km from Museum of Life and Science
8.4 out of 10, Very good, (1008)
"Older property but very convenient and clean for our quick trip. "
United States
Stacie
The price is Rp2.149.527
Rp2.439.714 total
includes taxes & fees
16 Dec - 17 Dec
The Lodge at Duke Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Museum of Life and Science Hotel Reviews

Unscripted Durham, Part of JDV by Hyatt

Unscripted Durham, Part of JDV by Hyatt

10/10 Excellent
"Nice"
isaiah 1-night trip
Posted 2 weeks ago
Unscripted Durham, Part of JDV by Hyatt

Hotels near other Museum of Life and Science attractions

Brightleaf Square

You can do some window-shopping at Brightleaf Square during your visit to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area.
See properties

Vietnam Veterans Living Memorial

You can find out about the history of Durham with a trip to Vietnam Veterans Living Memorial. Attend a sporting event or visit the stunning cathedral in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Museum of Life and Science?
Museum of Life and Science is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, take a look at the 9 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near Museum of Life and Science?
Hampton Inn & Suites Durham/North I-85 is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.8 mi (1.4 km) from Museum of Life and Science. Other good options within 5 miles include Red Roof Inn Durham - Duke Univ Medical Center and Holiday Inn Express Durham by IHG.
How many hotels can I expect to find close to Museum of Life and Science?
Expedia has 9 hotels and other accommodation options within a mile from Museum of Life and Science.
If I need to cancel the hotel reservation for my stay near Museum of Life and Science, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best deals near Museum of Life and Science.
What can I see and do near Museum of Life and Science?
You'll want to browse the exhibits at Nasher Museum of Art at Duke University and Bennett Place. Explore landmarks like American Tobacco Campus, Cameron Indoor Stadium and Wallace Wade Stadium. You can watch performances at Carolina Theatre, Durham Performing Arts Center and Manbites Dog Theater if you're interested in local theatre.

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