San Francisco Travel Guide

Panama City

Photo by Hideki Yamagata
Photo by ‎James Barrow
Photo by Adrian Damian
Photo by Nóra Széll
Photo by Panama Roadrunner

Popular places to visit

Things to do


Top hotels in San Francisco

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
The price is Rp2.500.649 per night from 31 Jan to 1 Feb
Rp2.500.649
Rp2.750.747 total
31 Jan - 1 Feb
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,019 reviews)
Going location, great city views

Reviewed on 4 Jan 2026

Las Americas Golden Tower Panama
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. ...
8.4/10 Very Good! (1,351 reviews)
El hotel nos brindó una excelente atención.

Reviewed on 4 Jan 2026

Megapolis Hotel Panamá
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla Panama City Panama
The price is Rp1.887.092 per night from 24 Jan to 25 Jan
Rp1.887.092
Rp2.075.801 total
24 Jan - 25 Jan
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the pool in their ...
9.2/10 Wonderful! (2,165 reviews)
The room was very nice with wrap around windows to see the skyline. Beds comfortable, breakfast was very good.

Reviewed on 6 Jan 2026

Plaza Paitilla Inn Hotel
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
Stay at this spa hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free valet parking. Our guests praise the breakfast and the helpful staff in their ...
8.4/10 Very Good! (1,485 reviews)
Nothing to write home about. Generally ok and clean but building is aging, pool opens late & closes early (10am - 8pm), sauna not free. Room missing some basic amenities & light bulbs, had to request. Breakfast buffet is decent but a bit disappointing in food options and presentation. Sushi restaurant ...

Reviewed on 7 Jan 2026

Decapolis Hotel Panama City
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
The price is Rp2.300.839 per night from 23 Jan to 24 Jan
Rp2.300.839
Rp2.530.923 total
23 Jan - 24 Jan
includes taxes & fees
Stay at this 4-star spa resort in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (1,003 reviews)
Our stay was exceptional overall, and we truly enjoyed our time at the hotel. The room was comfortable, the atmosphere was relaxing, and the service across the property was very good. We stayed in room 1122, and while nothing took away from the quality of our stay, there were a few maintenance items ...

Reviewed on 5 Jan 2026

Sheraton Grand Panama
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica Panama City Panama
The price is Rp4.860.691 per night from 7 Feb to 8 Feb
Rp4.860.691
Rp5.346.760 total
7 Feb - 8 Feb
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free Wi-Fi, 4 outdoor pools and 3 restaurants. Our guests praise the helpful staff in their reviews. Popular ...
8.8/10 Excellent! (1,004 reviews)
Clean room

Reviewed on 8 Jan 2026

JW Marriott Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around San Francisco

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Obarrio

Unique features of Obarrio include the casinos and coffee shops. Make a stop by Calle 50 or Soho City Center while you're exploring the area.

Obarrio
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Punta Pacifica

Notable for its seaside views, restaurants and casinos, Punta Pacifica is a sought-after destination for many travellers visiting Panama City. If you want to see some sights in the area, check out Avenida Balboa or Multiplaza Pacific Mall.

Punta Pacifica
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Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Punta Paitilla
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Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Crown Casino.

Bella Vista
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Pueblo Nuevo

While there might not be top attractions in Pueblo Nuevo, you can explore the larger area and discover places like El Dorado Mall and Multiplaza Pacific Mall.

Pueblo Nuevo
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Campo Alegre

3.5/5(5 area reviews)

If you're spending some time in Campo Alegre, Uruguay Street and Calle 50 are top sights worth seeing.

Campo Alegre


San Francisco Travel Guide