San Francisco Travel Guide

Panama City

Photo by Hideki Yamagata
Photo by ‎James Barrow
Photo by Adrian Damian
Photo by Nóra Széll
Photo by Panama Roadrunner

Popular places to visit

Things to do


Top hotels in San Francisco

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
The price is Rp2.929.743 per night from 10 Jan to 11 Jan
Rp2.929.743
Rp3.222.700 total
10 Jan - 11 Jan 2026
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,013 reviews)
It was a very nice stay. The room is nice, organized and clean with a great view of the city. The blankets are a little too warm and we wished for a lighter blankets. Breakfast buffet was very good with many food choices and best custom eggs cooked tailored to our demands. Uber to Casco Viejo was ...

Reviewed on 15 Dec 2025

Las Americas Golden Tower Panama
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
The price is Rp2.323.544 per night from 21 Dec to 22 Dec
Rp2.323.544
Rp2.555.898 total
21 Dec - 22 Dec
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. ...
8.4/10 Very Good! (1,284 reviews)
Amazing

Reviewed on 18 Dec 2025

Megapolis Hotel Panamá
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
The price is Rp2.121.387 per night from 9 Jan to 10 Jan
Rp2.121.387
Rp2.333.525 total
9 Jan - 10 Jan 2026
includes taxes & fees
Stay at this 4-star spa resort in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (993 reviews)
Yes

Reviewed on 11 Dec 2025

Sheraton Grand Panama
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla Panama City Panama
The price is Rp1.805.248 per night from 28 Dec to 29 Dec
Rp1.805.248
Rp1.985.856 total
28 Dec - 29 Dec
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the pool in their ...
9.2/10 Wonderful! (2,132 reviews)
Good

Reviewed on 19 Dec 2025

Plaza Paitilla Inn Hotel
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica Panama City Panama
The price is Rp4.959.675 per night from 10 Jan to 11 Jan
Rp4.959.675
Rp5.455.643 total
10 Jan - 11 Jan 2026
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free Wi-Fi, 4 outdoor pools and 3 restaurants. Our guests praise the helpful staff in their reviews. Popular ...
8.8/10 Excellent! (1,008 reviews)
Just wonderful hotel

Reviewed on 16 Dec 2025

JW Marriott Panama
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
The price is Rp1.917.520 per night from 20 Jan to 21 Jan
Rp1.917.520
Rp2.109.272 total
20 Jan - 21 Jan 2026
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free valet parking. Our guests praise the breakfast and the helpful staff in their ...
8.4/10 Very Good! (1,446 reviews)
Muito bom

Reviewed on 12 Dec 2025

Decapolis Hotel Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around San Francisco

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Obarrio

Unique features of Obarrio include the casinos and coffee shops. Make a stop by Calle 50 or Soho City Center while you're exploring the area.

Obarrio
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Punta Pacifica

Notable for its seaside views, restaurants and casinos, Punta Pacifica is a sought-after destination for many travellers visiting Panama City. If you want to see some sights in the area, check out Avenida Balboa or Multiplaza Pacific Mall.

Punta Pacifica
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Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Punta Paitilla
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Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Crown Casino.

Bella Vista
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Campo Alegre

3.5/5(5 area reviews)

If you're spending some time in Campo Alegre, Uruguay Street and Calle 50 are top sights worth seeing.

Campo Alegre
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Marbella

You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.

Marbella


San Francisco Travel Guide