Search Hotels Near Piazza Santo Spirito, Florence

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
22 Dec - 23 Dec
Tomorrow
23 Dec - 24 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Piazza Santo Spirito hotels

Royal Double Room | Minibar, in-room safe, soundproofing, free WiFi
Oltrarno Splendid

Oltrarno Splendid

Oltrarno Splendid
San Frediano, 0.2 km from Piazza Santo Spirito
10.0 out of 10, Exceptional, (97)
"It was Wonderful!!!"
United States
MARGARITA
The price is Rp2.578.027
Rp3.110.419 total
includes taxes & fees
18 Jan - 19 Jan 2026
Oltrarno Splendid
Front of property
Soprarno Suites

Soprarno Suites

Soprarno Suites
Historic Centre of Florence, 0.1 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (395)
"Beautiful rooms in ideal location and staff was friendly and helpful"
Canada
Dara
The price is Rp3.674.872
Rp4.316.949 total
includes taxes & fees
23 Dec - 24 Dec
Soprarno Suites
Lobby sitting area
AdAstra Suites

AdAstra Suites

AdAstra Suites
San Frediano, 0.2 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (221)
"Great Room - Lovely breakfast excellent strong Cappuccino and lovely yoghurts. Thanks see you soon. "
United Kingdom
Tim
The price is Rp3.032.973
Rp3.610.861 total
includes taxes & fees
18 Jan - 19 Jan 2026
AdAstra Suites
Courtyard
Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
San Frediano, 0.5 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (136)
"Ver clean and quiet, wonderful stay."
United States
kevin
Drom Florence Rooms & Apartments
Restaurant
Portrait Firenze - Lungarno Collection

Portrait Firenze - Lungarno Collection

Portrait Firenze - Lungarno Collection
5.0 star property
San Giovanni, 0.5 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (303)
"Great location and got fantastic service from the hotel. Room was very clean and comfortable. Definitely my first choice for staying in Firenze!"
Canada
LEI
The price is Rp15.013.306
Rp16.828.454 total
includes taxes & fees
8 Jan - 9 Jan 2026
Portrait Firenze - Lungarno Collection
Standard Double Room, City View (Tornabuoni Small Size Room) | Premium bedding, in-room safe, soundproofing, free WiFi
Toscanelli Residenza D'epoca

Toscanelli Residenza D'epoca

Toscanelli Residenza D'epoca
Historic Centre of Florence, 0.2 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (366)
"Great location with lots of sights and restaurants in walklng distance. "
Ireland
jennifer
The price is Rp1.540.558
Rp1.969.204 total
includes taxes & fees
19 Jan - 20 Jan 2026
Toscanelli Residenza D'epoca
Exclusive Suite | View from room
Palazzo Martellini Residenza d'Epoca

Palazzo Martellini Residenza d'Epoca

Palazzo Martellini Residenza d'Epoca
Historic Centre of Florence, 0.2 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (70)
"The whole experience was very pleasurable."
Canada
Dejan
Palazzo Martellini Residenza d'Epoca
Fireplace
Ottantotto Firenze

Ottantotto Firenze

Ottantotto Firenze
San Frediano, 0.2 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (169)
"Fabulous hotel , breakfast was amazing , great location "
United Kingdom
SAMANTHA
The price is Rp3.090.657
Rp3.674.313 total
includes taxes & fees
21 Jan - 22 Jan 2026
Ottantotto Firenze
Standard Loft | Premium bedding, memory-foam beds, in-room safe, laptop workspace
Numa Florence Palazzo Belfiore

Numa Florence Palazzo Belfiore

Numa Florence Palazzo Belfiore
Historic Centre of Florence, 0.2 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (371)
"Great property, plenty of space for my family. The location is great, we were able to walk everywhere including the train station. "
United States
Loren
The price is Rp2.564.992
Rp3.056.854 total
includes taxes & fees
11 Jan - 12 Jan 2026
Numa Florence Palazzo Belfiore
Aerial view
Ponte Vecchio Suites & Spa

Ponte Vecchio Suites & Spa

Ponte Vecchio Suites & Spa
4.0 star property
Historic Centre of Florence, 0.4 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (1001)
"Great location and beautiful accommodation "
United States
Amy
Ponte Vecchio Suites & Spa
Exterior
Hotel Lungarno - Lungarno Collection

Hotel Lungarno - Lungarno Collection

Hotel Lungarno - Lungarno Collection
5.0 star property
Historic Centre of Florence, 0.4 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (600)
"Excellent location! Truly a 5 star hotel ! Great service, breakfast, and service . Bedrooms were clean! Bathrooms were excellent!"
Canada
Pam
The price is Rp10.787.471
Rp12.180.035 total
includes taxes & fees
23 Dec - 24 Dec
Hotel Lungarno - Lungarno Collection
Food court
Leone Blu Suites | UNA Esperienze

Leone Blu Suites | UNA Esperienze

Leone Blu Suites | UNA Esperienze
Duomo, 0.5 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (195)
"We had a wonderful stay. Service was impeccable. Wonderful breakfast is recommended. Great location, comfortable bed and plenty of hot water pressure."
United States
Peter
The price is Rp4.956.887
Rp5.727.165 total
includes taxes & fees
23 Dec - 24 Dec
Leone Blu Suites | UNA Esperienze
Daily buffet breakfast (EUR 20.00 per person)
Antica Torre di Via Tornabuoni 1

Antica Torre di Via Tornabuoni 1

Antica Torre di Via Tornabuoni 1
Duomo, 0.5 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (583)
"Incredible location and services!"
United States
William
Antica Torre di Via Tornabuoni 1
Deluxe Room (Camera Deluxe Spaziosa) | View from room
Residenza Alessandra

Residenza Alessandra

Residenza Alessandra
San Giovanni, 0.5 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (77)
"Lovely apartment in an excellent location. Linked to a hotel so helpful for check-in and daily cleaning."
United Kingdom
Rosa
Residenza Alessandra
Interior
Tornabuoni View

Tornabuoni View

Tornabuoni View
Duomo, 0.5 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (310)
"Great Location and very friendly staff!"
United States
Aaron
Tornabuoni View
Reception
B & Beatrice

B & Beatrice

B & Beatrice
Historic Centre of Florence, 0.1 km from Piazza Santo Spirito
9.4 out of 10, Exceptional, (110)
"Good location Helpful staff"
United States
maryjo
The price is Rp1.711.677
Rp2.118.208 total
includes taxes & fees
23 Dec - 24 Dec
B & Beatrice
Lobby
Hotel Berchielli

Hotel Berchielli

Hotel Berchielli
4.0 star property
San Giovanni, 0.5 km from Piazza Santo Spirito
9.4 out of 10, Exceptional, (1001)
"Staff were all very accommodating and friendly. Breakfast buffet great and location of hotel wonderful"
United States
Polly
The price is Rp4.108.636
Rp4.794.090 total
includes taxes & fees
7 Jan - 8 Jan 2026
Hotel Berchielli
Property amenity
Hotel Continentale - Lungarno Collection

Hotel Continentale - Lungarno Collection

Hotel Continentale - Lungarno Collection
4.0 star property
San Giovanni, 0.5 km from Piazza Santo Spirito
9.4 out of 10, Exceptional, (728)
"Great location and a very clean hotel. Excellent staff. "
United States
Robert
The price is Rp5.830.583
Rp6.688.232 total
includes taxes & fees
21 Jan - 22 Jan 2026
Hotel Continentale - Lungarno Collection
Deluxe Studio | View from room
Le stanze degli amidei

Le stanze degli amidei

Le stanze degli amidei
San Giovanni, 0.5 km from Piazza Santo Spirito
9.4 out of 10, Exceptional, (123)
"Great location and amenities. Had everything we needed, including water!"
United States
Natalie
Le stanze degli amidei
Terrace/patio
Palazzo Alfieri Residenza d’epoca

Palazzo Alfieri Residenza d’epoca

Palazzo Alfieri Residenza d’epoca
Duomo, 0.4 km from Piazza Santo Spirito
9.2 out of 10, Wonderful, (727)
"This was such a lovely hotel! It was in a great location with an incredible view. The staff was great and the breakfast was absolutely fantastic! I would highly recommend this hotel "
United States
Christine
The price is Rp2.451.698
Rp2.971.458 total
includes taxes & fees
23 Dec - 24 Dec
Palazzo Alfieri Residenza d’epoca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Piazza Santo Spirito Hotel Reviews

Hotel Pendini

Hotel Pendini

10/10 Excellent
"Old hotel but clean room, friendly staff, and great location (central location to everything). We enjoyed breakfast every morning."
Noriko Tomioka 6-night trip
Posted 5 days ago
Hotel Pendini

Hotels near other Piazza Santo Spirito attractions

Santo Spirito Basilica

Learn about the local history of Florence when you take a trip to Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area.
See properties

Pitti Vintage

You can browse for the perfect souvenirs at Pitti Vintage during your trip to Florence. Stroll along the riverfront or visit the notable monuments in this vibrant area.
See properties

Frequently asked questions

What's the area like around Piazza Santo Spirito?
Piazza Santo Spirito is located in a historic area of Florence known for its stunning cathedral and popular art scene. If you're looking for a convenient place to stay, take a look at the 3052 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay close to Piazza Santo Spirito?
Adjacent to Piazza Santo Spirito, Palazzo Alfieri Residenza d'epoca is one of the top choices for your stay based on our traveller data, and this residence offers a fitness centre and a rooftop terrace. Other good choices close by include 25hours Hotel Florence Piazza San Paolino and Solo Experience Hotel.
How many hotels will I find close to Piazza Santo Spirito?
Expedia has 3052 hotels and other accommodation options within a mile from Piazza Santo Spirito.
If I need to cancel the hotel reservation for my stay near Piazza Santo Spirito, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to get the best deals near Piazza Santo Spirito.
What can I see and do near Piazza Santo Spirito?
Study the collections at Uffizi Gallery, Galileo Museum - Institute and Museum of the History of Science or Basilica of Santa Maria Novella. Via Maggio, Pitti Palace and Via de' Tornabuoni are landmarks that you won't want to miss. You can check out the local talent at Teatro Verdi, Visarno Arena and Teatro Comunale Florence.
How can I get to Piazza Santo Spirito?
With so many ways to get around, seeing all of the area near Piazza Santo Spirito is easy. Nearby metro stations include Unità Tram Stop, Valfonda - Stazione Santa Maria Novella Tram Stop and San Marco University Tram Stop. If you're taking a train into town, Florence (ZMS-Santa Maria Novella Train Station) and Florence Santa Maria Novella Station are the closest stops to Historic Centre of Florence.