Find hotels in Santa Ana from Rp509.200

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23 Dec - 24 Dec
Tomorrow
24 Dec - 25 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for Santa Ana hotels

Exterior
QUINTA MARIA ISABEL

QUINTA MARIA ISABEL

QUINTA MARIA ISABEL
3.0 star property
Gualaceo
10.0 out of 10, Exceptional, (1)
Set in Gualaceo's entertainment district, this charming colonial retreat offers complimentary continental breakfast daily. Enjoy the tranquil garden and terrace, or explore nearby Gualaceo Market and Ecuagenera Orchids. The 24-hour front desk ensures convenience throughout your stay.
The price is Rp904.500
Rp904.500 total
6 Jan - 7 Jan 2026
QUINTA MARIA ISABEL
Outdoor pool
Uzhupud Garden Hotel & lodge

Uzhupud Garden Hotel & lodge

Uzhupud Garden Hotel & lodge
3.0 star property
Paute
8.6 out of 10, Excellent, (36)
This garden hotel offers a peaceful escape with outdoor swimming pools for both adults and children. Unwind at the bar or grab a bite at the café. Near Lineal Park and Adrenalina Kart Racing, with convenient access to Cuenca.
"Wonderful relaxing area. "
United States
Melany
Uzhupud Garden Hotel & lodge
Indoor pool
Twelve Hummingbirds Andes Retreat

Twelve Hummingbirds Andes Retreat

Twelve Hummingbirds Andes Retreat
4.5 star property
Dugdug
Escape to the Andes at this luxury hotel offering massages, facials, and detox wraps. Enjoy the indoor pool, fitness centre, and bar after exploring nearby Lineal Park. Free breakfast, WiFi, and parking enhance your mountain getaway.
The price is Rp2.010.000
Rp2.010.000 total
24 Dec - 25 Dec
Twelve Hummingbirds Andes Retreat
Outdoor pool
Arhaná Hostería Resort

Arhaná Hostería Resort

Arhaná Hostería Resort
3.5 star property
Gualaceo
8.4 out of 10, Very good, (16)
Escape to this family-friendly resort featuring an outdoor pool, hot tub, and sauna. Enjoy international cuisine at Mikuna restaurant and sip drinks at the bar. Near Adrenalina Kart Racing and Ecuagenera Orchids with free breakfast, WiFi, and parking.
"a pleasant stay as usual"
United States
Juan
The price is Rp1.172.500
Rp1.172.500 total
27 Dec - 28 Dec
Arhaná Hostería Resort
Terrace/patio
Hotel Cruz del Vado by Art Hotels Ecuador

Hotel Cruz del Vado by Art Hotels Ecuador

Hotel Cruz del Vado by Art Hotels Ecuador
4.5 star property
Cuenca
9.4 out of 10, Exceptional, (40)
Experience refined comfort at this Cuenca gem with free breakfast and WiFi. Unwind at the bar or dine at the on-site restaurant after exploring nearby San Sebastian Plaza and Museum of Modern Art. Just 12 minutes from the airport.
"Excellent service. I was pregnant and the wokers were very attentive. If you want to have a beautiful experience, It’s worth staying here."
United States
Yenifer
The price is Rp3.261.449
Rp3.587.594 total
12 Jan - 13 Jan 2026
Hotel Cruz del Vado by Art Hotels Ecuador
Courtyard
Mansión Alcázar Boutique Hotel

Mansión Alcázar Boutique Hotel

Mansión Alcázar Boutique Hotel
4.0 star property
Downtown Cuenca
9.6 out of 10, Exceptional, (332)
Set in Cuenca's heart, this boutique hotel combines old-world elegance with modern comforts. Unwind with hot stone massages at the full-service spa, savour local cuisine at Casa Alonso, or relax in the sauna after exploring nearby San Francisco Plaza Market.
"Food and service was great "
United States
frank
The price is Rp2.306.475
Rp2.537.123 total
24 Dec - 25 Dec
Mansión Alcázar Boutique Hotel
Front of property – evening/night
Villa Ana Maria Cuenca

Villa Ana Maria Cuenca

Villa Ana Maria Cuenca
3.5 star property
Cuenca
6.6 out of 10, (9)
Set in Cuenca, this welcoming hotel offers La Chococafetería among its 3 restaurants serving international cuisine. Enjoy complimentary breakfast, WiFi, and parking while exploring nearby attractions like Río Burgay. A terrace and garden provide peaceful outdoor spaces.
"Llegando y no había reserva, no tenían habitaciones.. todo mal "
Mexico
Stefano
The price is Rp1.842.500
Rp1.842.500 total
5 Jan - 6 Jan 2026
Villa Ana Maria Cuenca
Superior Duplex, 1 Bedroom | Down duvets, Select Comfort beds, in-room safe, blackout curtains
Hotel Raymipampa

Hotel Raymipampa

Hotel Raymipampa
3.5 star property
Downtown Cuenca
9.6 out of 10, Exceptional, (71)
Within walking distance to Convent of the Assumption and San Francisco Plaza Market, this hotel offers free continental breakfast and WiFi. Gaspar Sangurima Tram Station is just 11 minutes away, and Antonio Borrero Station is an easy 5-minute stroll.
"Everything about my stay has been fantastic! The hotel has old world charm and the staff have been superb! My every need has been taken care of. "
United States
Cheistopher
The price is Rp778.875
Rp1.197.625 total
26 Dec - 27 Dec
Hotel Raymipampa
Pool
Four Points By Sheraton Cuenca

Four Points By Sheraton Cuenca

Four Points By Sheraton Cuenca
3.5 star property
Cuenca
9.0 out of 10, Wonderful, (419)
Immerse yourself in Cuenca's charm at this welcoming hotel with free breakfast and WiFi. After visiting nearby Mall del Rio, unwind in the health club, sauna, or hot tub. The restaurant and bar provide delicious dining options with exceptional service.
"The place was perfect clean and the the staff very kind "
United States
Diana Patricia Asmal
The price is Rp1.608.000
Rp1.768.800 total
28 Dec - 29 Dec
Four Points By Sheraton Cuenca
Egyptian cotton sheets, premium bedding, in-room safe, desk
TRYP by Wyndham Cuenca Zahir

TRYP by Wyndham Cuenca Zahir

TRYP by Wyndham Cuenca Zahir
4.0 star property
Downtown Cuenca
8.6 out of 10, Excellent, (458)
Enjoy free breakfast, WiFi, and parking at this boutique hotel just 12 minutes from Cuenca Airport. The 24-hour fitness centre keeps you active while the fusion restaurant and stylish bar provide refreshment after exploring nearby Yanuncay Tram Station.
"Very clean place, excellent staff, great breakfast included "
United States
JUAN
The price is Rp1.675.000
Rp1.842.500 total
24 Dec - 25 Dec
TRYP by Wyndham Cuenca Zahir
2 restaurants, breakfast, lunch, dinner served; Italian cuisine
Hotel Boutique Santa Lucia

Hotel Boutique Santa Lucia

Hotel Boutique Santa Lucia
4.0 star property
Downtown Cuenca
9.2 out of 10, Wonderful, (370)
This boutique hotel offers 2 restaurants including SANTA LUCIA serving Italian cuisine. Just minutes from Calderon Park and 5 min from the airport with complimentary shuttle, parking, and breakfast. A terrace, bar, and excellent staff enhance your stay.
"Was a espectacular hotel thanx for all guys "
United States
Pablo
The price is Rp1.793.924
Rp1.973.317 total
23 Jan - 24 Jan 2026
Hotel Boutique Santa Lucia
Reception
Santa Lucia House - Forum

Santa Lucia House - Forum

Santa Lucia House - Forum
4.0 star property
Downtown Cuenca
9.4 out of 10, Exceptional, (469)
Just a 12-minute drive from the airport, this welcoming hotel offers free breakfast, WiFi, and parking. Unwind at the bar after exploring nearby Plaza Rotary Market and Civic Plaza. With tram stations only minutes away, city adventures are effortless.
"All the employees very helpful and friendly, breakfast really good and delicious, room very clean with everything needed."
United States
CLEMENTE
The price is Rp1.193.946
Rp1.313.341 total
24 Dec - 25 Dec
Santa Lucia House - Forum
Restaurant
Vaway Hotel

Vaway Hotel

Vaway Hotel
3.0 star property
Downtown Cuenca
9.0 out of 10, Wonderful, (104)
This business-friendly hotel offers free WiFi and self parking. Explore Convent of the Assumption and San Francisco Plaza Market nearby, or catch public transit from Antonio Borrero Station just 6 minutes away. The rooftop terrace provides a relaxing space after city adventures.
"Clean room and friendly staff. Beautiful neighborhood right in the heart of the historic district."
United States
Sandra
Vaway Hotel
Deluxe Double Room, Balcony, City View | Free WiFi
Melody Hotel

Melody Hotel

Melody Hotel
2.0 star property
Downtown Cuenca
8.0 out of 10, Very good, (3)
This centrally located B&B offers continental breakfast and WiFi at no charge. Just 6 minutes from Luis Cordero Station and 10 minutes from Gaspar Sangurima Tram, you'll easily reach Las Conceptas Museum and Museum of the Canari Identity.
"It is NOT a hotel. It is more like"
United States
Johanna
The price is Rp1.055.250
Rp1.055.250 total
24 Dec - 25 Dec
Melody Hotel
Garden
Apartamentos Otorongo

Apartamentos Otorongo

Apartamentos Otorongo
3.0 star property
Cuenca
10.0 out of 10, Exceptional, (2)
Situated near Unidad Nacional Tram Station, this apartment offers all the conveniences of home with full kitchens and Smart TVs. Museum of Modern Art and San Sebastian Plaza are just moments away, while rainfall showerheads add a touch of luxury to your Ecuadorian adventure.
"The space is big and bright with loads of natural light. Clean, with tile floors. Fridge, stove and whatever you need to cook for yourself. Right by the river"
United States
Allan
The price is Rp640.855
Rp640.855 total
6 Jan - 7 Jan 2026
Apartamentos Otorongo
Outdoor pool, pool umbrellas, pool loungers
Oro Verde Cuenca

Oro Verde Cuenca

Oro Verde Cuenca
4.5 star property
San Sebastián
9.4 out of 10, Exceptional, (544)
Elegant rooms await at this luxury hotel with an outdoor pool, sauna, and 24-hour airport shuttle. Only minutes from Museum of Modern Art and tram stations, the property offers free breakfast, WiFi, and parking, with local cuisine at Altitud restaurant.
"Great service, staff, clean rooms. "
United States
Claudia
The price is Rp1.591.250
Rp1.750.375 total
28 Dec - 29 Dec
Oro Verde Cuenca
Deluxe Double Room, Private Bathroom, River View | Down duvets, pillow-top beds, minibar, in-room safe
Hostal Kolibri

Hostal Kolibri

Hostal Kolibri
3.5 star property
Huayna-Cápac
9.6 out of 10, Exceptional, (18)
"Desde el primer dia la atencion y el don de servicio fue excelente. Los recomiendo y volvería una vez mas. El rio que esta al frente sinceramente hermoso"
Mexico
Lorena
The price is Rp1.038.500
Rp1.038.500 total
24 Dec - 25 Dec
Hostal Kolibri
Front of property
Hotel Boutique Magdalena By Chat Noir

Hotel Boutique Magdalena By Chat Noir

Hotel Boutique Magdalena By Chat Noir
3.0 star property
Downtown Cuenca
9.2 out of 10, Wonderful, (9)
Relax at this charming Cuenca retreat offering indulgent spa massages and a refreshing indoor pool. Just a 9-minute walk from Antonio Borrero Station and near Sombrero Museum. Enjoy complimentary breakfast and WiFi during your cultural exploration.
"All good. The suite has a great view of the cathedral "
United States
David
The price is Rp539.350
Rp706.850 total
22 Jan - 23 Jan 2026
Hotel Boutique Magdalena By Chat Noir
Terrace/patio
Casa 11-24 by Casa Bolivar

Casa 11-24 by Casa Bolivar

Casa 11-24 by Casa Bolivar
2.0 star property
Downtown Cuenca
9.8 out of 10, Exceptional, (8)
Located steps from Antonio Borrero Station, this charming B&B offers free continental breakfast each morning. Explore nearby San Sebastian Plaza and Museum of Modern Art, then return to comfortable accommodation with complimentary WiFi and convenient laundry facilities.
"Clean, safe. Good location. Easy to get to. Clear instructions on how Casa Bolivar works. "
United States
Dario
The price is Rp705.510
Rp705.510 total
5 Jan - 6 Jan 2026
Casa 11-24 by Casa Bolivar
Interior detail
Hotel & Suites El Quijote

Hotel & Suites El Quijote

Hotel & Suites El Quijote
3.0 star property
Downtown Cuenca
7.6 out of 10, Good, (7)
"The hotel was well situated and easy to get to. Walking distance to many activities, shops churches and museums etc Room was nice and clean each time we returned from our outings. The only inconvenience was not being able to go out early for church service as the hotel was closed until 7.30am. A Comfortable stay in beautiful city that Cuenca turned out to be. "
Australia
Marlene
The price is Rp746.073
Rp857.976 total
24 Dec - 25 Dec
Hotel & Suites El Quijote
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Ana Hotel Reviews

Hotel Azul de la Plaza

Hotel Azul de la Plaza

10/10 Excellent
"Great location, service and value for money. The staff were very helpful and assisted us in calling taxi and answering all the questions we had about Cuenca. Highly recommended"
Mohammed 4-night trip
Posted 2 months ago
Hotel Azul de la Plaza

More cheap stays in Santa Ana

Hotel Boutique La Ronda by Chat Noir

Hotel Boutique La Ronda by Chat Noir

calle larga y presidente Borrero Cuenca Azuay
The price is Rp610.537 per night from 29 Dec to 30 Dec
Rp610.537
Rp610.537 total
29 Dec - 30 Dec
8.8/10 Excellent! (41 reviews)

Frequently asked questions

What's the best place for a stay in Santa Ana?
Located 8.4 mi (13.5 km) from the heart of Santa Ana, Oro Verde Cuenca is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are Apartamento 3 habitaciones y parqueo and TRYP by Wyndham Cuenca Zahir. See all available top hotels, or vacation rentals in Santa Ana.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Ana.
What is staying in Santa Ana like?
Visitors to Santa Ana will definitely find plenty to explore and enjoy. There are 377 hotels and other accommodation options in the surrounding area. Find out more about Santa Ana.
What should I see while I'm in Santa Ana?
Places to visit in the wider area include Mirador de Turi, Puente Roto and Alejandro Serrano Aguilar Stadium. You'll also find Río Tomebamba & Calle Larga and Plaza Rotary Market in the area. Take a look at what more there is to see and do in Expedia's Santa Ana guide.
What's the seasonal weather in Santa Ana?
The hottest months are usually November and October, with an average temperature of 13°C, while the coldest months are July and August, with an average of 11°C. The rainiest months in Santa Ana are April, March, February and January, with each month seeing an average of 327 mm of rainfall.