Santa Ana Travel Guide

Antigua Guatemala

A white colonial church with ornate architecture and a large wooden door.

Things to do


Top hotels in Santa Ana

Barceló Guatemala City

Barceló Guatemala City

4.5 out of 5
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
The price is Rp1.770.942 per night from 25 Oct to 26 Oct
Rp1.770.942
Rp2.160.549 total
25 Oct - 26 Oct
includes taxes & fees
Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the breakfast and the pool in their reviews. ...
9.2/10 Wonderful! (3,311 reviews)
"Loved it"

Reviewed on 8 Oct 2026

Barceló Guatemala City
Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

4.5 out of 5
3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
Fully refundableReserve now, pay when you stay
The price is Rp4.409.145 per night from 13 Oct to 14 Oct
Rp4.409.145
Rp5.597.379 total
13 Oct - 14 Oct
includes taxes & fees
Stay at this luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa and 2 restaurants. Our guests praise the helpful staff and the property ...
Hotel Museo Spa Casa Santo Domingo
Wyndham Garden Guatemala City

Wyndham Garden Guatemala City

4 out of 5
1a Avenida 12-46 Zona 10 Guatemala City Guatemala
The price is Rp1.675.052 per night from 1 Nov to 2 Nov
Rp1.675.052
Rp2.043.563 total
1 Nov - 2 Nov
includes taxes & fees
Stay at this business-friendly hotel in Guatemala City. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,933 reviews)
"Stay for 5 days The place was beautiful also walking distance to everything shop, restaurant ,mall, etc. the hotel driver Mr. Caesar is the best very patient no complain about him."

Reviewed on 8 Oct 2026

Wyndham Garden Guatemala City
Adriatika Hotel & Residence

Adriatika Hotel & Residence

4.5 out of 5
4 av 20-44 Zona 14 Guatemala City Guatemala
The price is Rp1.926.356 per night from 11 Oct to 12 Oct
Rp1.926.356
Rp2.350.155 total
11 Oct - 12 Oct
includes taxes & fees
Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms ...
9.6/10 Exceptional! (1,008 reviews)
"Very convenient"

Reviewed on 7 Oct 2026

Adriatika Hotel & Residence
Hotel Camino Real Antigua

Hotel Camino Real Antigua

4 out of 5
7a Calle Poniente 33B Antigua Guatemala Sacatepequez
The price is Rp3.380.643 per night from 11 Oct to 12 Oct
Rp3.380.643
Rp4.571.559 total
11 Oct - 12 Oct
includes taxes & fees
Stay at this spa hotel in Antigua Guatemala. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
Hotel Camino Real Antigua
Hotel Biltmore Guatemala

Hotel Biltmore Guatemala

3.5 out of 5
15 Calle 0-31, Zona 10 Guatemala City Guatemala
The price is Rp1.580.103 per night from 1 Nov to 2 Nov
Rp1.580.103
Rp1.927.725 total
1 Nov - 2 Nov
includes taxes & fees
Stay at this business-friendly hotel in Guatemala City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff in their ...
Hotel Biltmore Guatemala
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Historic Center

If you're spending some time in Historic Center, Central Park and Santa Catalina Arch are top sights worth seeing.

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.



Santa Ana Travel Guide