Find hotels in Santa Cruz from Rp598.102

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Check prices for these dates

Tonight
28 Dec - 29 Dec
Tomorrow
29 Dec - 30 Dec
Next weekend
2 Jan - 4 Jan
In two weeks
9 Jan - 11 Jan

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Our top choices for Santa Cruz hotels

Front of property
Hotel El Zarzo

Hotel El Zarzo

Hotel El Zarzo
4.0 star property
El Poblado
9.6 out of 10, Exceptional, (251)
"Great hotel and location. Amazing staff and very clean. "
United States
Jeremy
The price is Rp2.887.977
Rp2.887.977 total
5 Jan - 6 Jan 2026
Hotel El Zarzo
Front of property
HOTEL SELIS

HOTEL SELIS

HOTEL SELIS
3.5 star property
El Poblado
9.6 out of 10, Exceptional, (295)
"Clean room nice staff"
United States
Arlene
The price is Rp1.370.901
Rp1.370.901 total
5 Jan - 6 Jan 2026
HOTEL SELIS
Restaurant
23Hotel Medellin

23Hotel Medellin

23Hotel Medellin
3.5 star property
El Poblado
9.4 out of 10, Exceptional, (346)
"Great place "
Mexico
David
23Hotel Medellin
Restaurant
The Click Clack Hotel Medellin

The Click Clack Hotel Medellin

The Click Clack Hotel Medellin
5.0 star property
El Poblado
9.2 out of 10, Wonderful, (1076)
"Great hotel."
United States
Luz Alma
The price is Rp3.500.908
Rp3.500.908 total
20 Jan - 21 Jan 2026
The Click Clack Hotel Medellin
Terrace/patio
The Somos Bold Hotel

The Somos Bold Hotel

The Somos Bold Hotel
4.0 star property
El Poblado
9.4 out of 10, Exceptional, (228)
"WAS PERFECT!"
Canada
Irina
The price is Rp1.685.492
Rp1.685.492 total
15 Jan - 16 Jan 2026
The Somos Bold Hotel
Al fresco dining
Selvario 36 Hotel

Selvario 36 Hotel

Selvario 36 Hotel
4.0 star property
El Poblado
9.4 out of 10, Exceptional, (590)
"We really loved the FOOD and drinks at the hotel. The staff was friendly and fully bilingual. They were helpful in telling us great places to visit nearby and I felt extremely safe during my stay."
United States
Tonya
The price is Rp3.822.970
Rp3.822.970 total
8 Jan - 9 Jan 2026
Selvario 36 Hotel
Reception
The Host Medellin Only Adults

The Host Medellin Only Adults

The Host Medellin Only Adults
3.0 star property
El Poblado
9.8 out of 10, Exceptional, (13)
"Great ambience and room, excellent breakfast "
United States
Shailendra
The price is Rp2.538.881
Rp2.538.881 total
1 Jan - 2 Jan 2026
The Host Medellin Only Adults
32-inch TV with cable channels
The Art Hotel Medellin

The Art Hotel Medellin

The Art Hotel Medellin
3.5 star property
El Poblado
7.8 out of 10, Good, (1000)
"The staff was great! It was really close to everything in El Poblado. The restaurant was really good too. Definitely recommend!"
United States
Miguel Jose Sanchez
The price is Rp1.409.218
Rp1.409.218 total
30 Dec - 31 Dec
The Art Hotel Medellin
Property grounds
ANTÍPODA HOTEL

ANTÍPODA HOTEL

ANTÍPODA HOTEL
3.0 star property
El Poblado
9.2 out of 10, Wonderful, (180)
"Great location clean room and great staff. A bit noisy though"
Canada
Yuting
The price is Rp915.828
Rp1.141.868 total
29 Dec - 30 Dec
ANTÍPODA HOTEL
Free daily buffet breakfast
Hotel Du Parc

Hotel Du Parc

Hotel Du Parc
4.5 star property
El Poblado
9.4 out of 10, Exceptional, (1004)
"Great hotel. Excellent and friendly staff. Breakfast is fantastic. Great location. "
United States
Steven
The price is Rp2.797.855
Rp2.797.855 total
4 Jan - 5 Jan 2026
Hotel Du Parc
Arcade
Diez Hotel Categoria Colombia

Diez Hotel Categoria Colombia

Diez Hotel Categoria Colombia
4.0 star property
El Poblado
9.4 out of 10, Exceptional, (1006)
"This hotel is so good , stay here when I go to Medellin "
United States
Luis
The price is Rp1.963.363
Rp1.963.363 total
19 Jan - 20 Jan 2026
Diez Hotel Categoria Colombia
Standard Double Room, 2 Queen Beds | Hypo-allergenic bedding, down duvets, pillow-top beds, minibar
The Somos Beats Hotel & Rooftop

The Somos Beats Hotel & Rooftop

The Somos Beats Hotel & Rooftop
3.5 star property
El Poblado
8.4 out of 10, Very good, (348)
"Great stay no complaints at all "
United States
Casey
The price is Rp1.388.052
Rp1.388.052 total
4 Jan - 5 Jan 2026
The Somos Beats Hotel & Rooftop
Indoor pool, outdoor pool, pool loungers
York Medellin, Curio Collection by Hilton

York Medellin, Curio Collection by Hilton

York Medellin, Curio Collection by Hilton
4.0 star property
El Poblado
9.6 out of 10, Exceptional, (1427)
"The rooms were clean, the view was stunning, and the staff were incredibly friendly and professional."
United States
RAMON
The price is Rp2.157.259
Rp2.157.259 total
4 Jan - 5 Jan 2026
York Medellin, Curio Collection by Hilton
Reception
Moet Medellin Hotel

Moet Medellin Hotel

Moet Medellin Hotel
3.0 star property
El Poblado
9.2 out of 10, Wonderful, (126)
"Very clean and friendly environment "
United States
Jennifer
Moet Medellin Hotel
Bar (on property)
Binn Hotel

Binn Hotel

Binn Hotel
4.5 star property
El Poblado
9.2 out of 10, Wonderful, (1004)
"Excellent hotel and staff! Rooftop restaurant and pool was amazing "
Canada
Sahar
The price is Rp3.382.123
Rp3.382.123 total
10 Jan - 11 Jan 2026
Binn Hotel
Terrace/patio
Lettera Hotel

Lettera Hotel

Lettera Hotel
3.5 star property
El Poblado
9.8 out of 10, Exceptional, (456)
"Excellent hotel and staff "
United States
Jose
Lettera Hotel
Front of property
Hotel Lleras 10

Hotel Lleras 10

Hotel Lleras 10
3.0 star property
El Poblado
8.2 out of 10, Very good, (334)
"Great hotel , staff is great "
United States
Luis
Hotel Lleras 10
Superior Double Room, 1 Queen Bed | Minibar, in-room safe, desk, blackout curtains
Hotel Lagoon

Hotel Lagoon

Hotel Lagoon
3.5 star property
Rionegro
9.2 out of 10, Wonderful, (301)
"Nice property, very good food, very relaxing."
United States
Kevin
The price is Rp2.275.413
Rp2.275.413 total
6 Jan - 7 Jan 2026
Hotel Lagoon
Terrace/patio
Landmark Hotel

Landmark Hotel

Landmark Hotel
4.0 star property
El Poblado
9.6 out of 10, Exceptional, (232)
"Very nice hotel. "
United States
Andres F.
The price is Rp2.328.710
Rp2.328.710 total
13 Jan - 14 Jan 2026
Landmark Hotel
Jetted bathtub
La Martina Boutique Hotel

La Martina Boutique Hotel

La Martina Boutique Hotel
3.5 star property
El Poblado
8.4 out of 10, Very good, (290)
"Very nice hotel, will be staying here again when I come back to Medellín "
United States
Ryan
La Martina Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Landmark Hotel

Landmark Hotel

10/10 Excellent
"I loved everything about this hotel! It’s a super stylish hotel in a great location in Poblado. The staff were amazing, the room super perfect for my wife, son and I, and the complimentary restaurant breakfast was delicious. I would highly recommend this hotel if you want to stay in a cool, vibrant and quiet area of Medellin. "
mark 2-night trip
Posted 2 days ago
Landmark Hotel

More cheap stays in Santa Cruz

Hotel Villanueva Comfort

Hotel Villanueva Comfort

57-12 Cra. 49 Medellín Antioquia
The price is Rp598.102 per night from 31 Dec to 1 Jan
Rp598.102
Rp598.102 total
31 Dec - 1 Jan 2026
8.6/10 Excellent! (29 reviews)

Frequently asked questions

Where is the best place to stay in Santa Cruz?
Located 5.9 mi (9.4 km) from the heart of Santa Cruz, Heiss Hotel By Jalo is a top choice for your stay, based on our traveller data. Two other options for your stay in the area are Calle Flora Hotel by Jalo and York Medellin, Curio Collection by Hilton. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best holiday rentals that Santa Cruz has to offer?
La Gracia Hotel & Spa: This holiday home rental outside of Santa Cruz offers a terrace, a garden and free WiFi to help you feel perfectly comfortable in your new surroundings. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! Most hotel bookings are fully refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What is staying in Santa Cruz like?
Visitors will definitely enjoy all that Santa Cruz has to offer. In Santa Cruz, there are 3 hotels and other accommodation options to choose from. Find out more about Santa Cruz.
What should I do while I'm visiting Santa Cruz?
Places to visit in the wider area include Medellin Botanical Garden, Explora Park and Arvi Park. You'll also find Antioquia Museum and Botero Plaza in the area. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.
How can I get around Santa Cruz?
Make your way to Andalucía MetroCable Station for metro travel. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the seasonal weather in Santa Cruz?
The hottest months are usually August and July, with an average temperature of 19°C, while the coldest months are December and January, with an average of 18°C. The rainiest months in Santa Cruz are May, April, October and November, with each month seeing an average of 406 mm of rainfall.