Search Hotels in Serra Highlands, San Francisco

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Check prices for these dates

Tonight
22 Dec - 23 Dec
Tomorrow
23 Dec - 24 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for Serra Highlands hotels

Lobby sitting area
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf
4.0 star property
17 km from Serra Highlands
9.0 out of 10, Wonderful, (7220)
"Great place to stay!"
United States
Isaiah
The price is Rp1.800.153
Rp2.808.789 total
includes taxes & fees
5 Jan - 6 Jan 2026
Hotel Riu Plaza Fisherman's Wharf
Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds
Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf
4.0 star property
16.9 km from Serra Highlands
9.0 out of 10, Wonderful, (3842)
"Excellent stay and great location! "
United States
CHRISTINE
The price is Rp2.037.386
Rp3.166.727 total
includes taxes & fees
22 Jan - 23 Jan 2026
Hotel Caza Fisherman's Wharf
Terrace/patio
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco
4.0 star property
15.9 km from Serra Highlands
8.8 out of 10, Excellent, (2819)
"Clean room, friendly staff and good location"
United States
Jose Eduardo
The price is Rp1.528.049
Rp1.798.438 total
includes taxes & fees
25 Dec - 26 Dec
Club Quarters Hotel in San Francisco
Lobby
Hilton San Francisco Financial District

Hilton San Francisco Financial District

Hilton San Francisco Financial District
4.0 star property
15.9 km from Serra Highlands
8.6 out of 10, Excellent, (2159)
"Great hotel "
United States
Tanya
The price is Rp1.953.385
Rp2.299.036 total
includes taxes & fees
25 Dec - 26 Dec
Hilton San Francisco Financial District
Exterior
Aloft San Francisco Airport

Aloft San Francisco Airport

Aloft San Francisco Airport
3.0 star property
8.7 km from Serra Highlands
9.0 out of 10, Wonderful, (2244)
"All good, friendly staff, spotless room. "
United States
Michael
The price is Rp1.680.025
Rp1.931.105 total
includes taxes & fees
29 Dec - 30 Dec
Aloft San Francisco Airport
Courtyard
Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront
4.0 star property
12 km from Serra Highlands
8.6 out of 10, Excellent, (2756)
"Nice airport hotel…staff was great, breakfast was amazing "
United States
Lynne
The price is Rp1.568.314
Rp1.783.094 total
includes taxes & fees
3 Jan - 4 Jan 2026
Hilton San Francisco Airport Bayfront
Exterior
The Westin San Francisco Airport

The Westin San Francisco Airport

The Westin San Francisco Airport
4.0 star property
8.8 km from Serra Highlands
8.8 out of 10, Excellent, (2029)
"Comfortable room, welcome glass of wine, easy shuttle to and from airport, friendly staff."
United States
Carole
The price is Rp1.723.910
Rp2.471.853 total
includes taxes & fees
25 Dec - 26 Dec
The Westin San Francisco Airport
Lobby sitting area
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

Chancellor Hotel on Union Square
3.5 star property
15.1 km from Serra Highlands
9.4 out of 10, Exceptional, (3093)
"Great hotel, great location, super friendly all staff "
Mexico
Claudia
The price is Rp1.268.644
Rp1.499.032 total
includes taxes & fees
4 Jan - 5 Jan 2026
Chancellor Hotel on Union Square
Breakfast and dinner served
DoubleTree by Hilton San Francisco Airport North Bayfront

DoubleTree by Hilton San Francisco Airport North Bayfront

DoubleTree by Hilton San Francisco Airport North Bayfront
4.0 star property
5.8 km from Serra Highlands
8.0 out of 10, Very good, (1335)
"Great location, clean and comfortable beds "
United States
Rubia
The price is Rp1.444.500
Rp1.706.350 total
includes taxes & fees
2 Jan - 3 Jan 2026
DoubleTree by Hilton San Francisco Airport North Bayfront
Bar (on property)
Hotel Shattuck Plaza

Hotel Shattuck Plaza

Hotel Shattuck Plaza
4.0 star property
28.5 km from Serra Highlands
8.8 out of 10, Excellent, (1088)
"Wonderful, will stay here again."
United States
Jennifer
Hotel Shattuck Plaza
Lounge
King George Hotel

King George Hotel

King George Hotel
3.0 star property
14.8 km from Serra Highlands
8.6 out of 10, Excellent, (2112)
"Great place!"
United States
Troy
The price is Rp1.423.248
Rp1.926.418 total
includes taxes & fees
24 Dec - 25 Dec
King George Hotel
Hypo-allergenic bedding, in-room safe, desk, laptop workspace
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG
3.5 star property
15 km from Serra Highlands
9.0 out of 10, Wonderful, (5033)
"Rooms were great, staff was great, location was great. "
United States
Jonathan
The price is Rp1.993.250
Rp2.346.005 total
includes taxes & fees
24 Dec - 25 Dec
Holiday Inn Golden Gateway by IHG
Courtyard
Hotel Zephyr San Francisco

Hotel Zephyr San Francisco

Hotel Zephyr San Francisco
4.0 star property
17 km from Serra Highlands
8.6 out of 10, Excellent, (2339)
"Great decor and really great location"
United States
Jose
The price is Rp2.237.130
Rp3.224.433 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Zephyr San Francisco
Exterior
Handlery Union Square Hotel

Handlery Union Square Hotel

Handlery Union Square Hotel
3.5 star property
14.9 km from Serra Highlands
8.8 out of 10, Excellent, (2798)
"Clean hotel, great location, kind staff! "
United States
Felix
The price is Rp17.574.938
Rp20.684.823 total
includes taxes & fees
11 Jan - 12 Jan 2026
Handlery Union Square Hotel
Indoor pool
Hotel Nikko San Francisco

Hotel Nikko San Francisco

Hotel Nikko San Francisco
4.5 star property
14.7 km from Serra Highlands
9.4 out of 10, Exceptional, (2658)
"Great service, great location, great hotel. "
United States
Laura
The price is Rp2.548.512
Rp3.769.531 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Nikko San Francisco
Lobby
Hotel 1550

Hotel 1550

Hotel 1550
3.5 star property
6.5 km from Serra Highlands
9.0 out of 10, Wonderful, (1047)
"Great front desk experience, nice room and very convenient to the airport. "
United States
Elmaz
The price is Rp1.724.580
Rp2.040.078 total
includes taxes & fees
16 Jan - 17 Jan 2026
Hotel 1550
Daily buffet breakfast (USD 22 per person)
citizenM San Francisco Union Square

citizenM San Francisco Union Square

citizenM San Francisco Union Square
4.0 star property
14.8 km from Serra Highlands
9.4 out of 10, Exceptional, (1431)
"Great service, great room!!"
United States
Arlindo
The price is Rp1.979.012
Rp2.329.197 total
includes taxes & fees
1 Jan - 2 Jan 2026
citizenM San Francisco Union Square
Two Queens Deluxe Room | Desk, blackout curtains, soundproofing, free WiFi
Good Nite Inn - Redwood City

Good Nite Inn - Redwood City

Good Nite Inn - Redwood City
2.5 star property
26 km from Serra Highlands
8.6 out of 10, Excellent, (1526)
"Just a nice stay"
United States
Francisco
The price is Rp1.423.750
Rp1.608.168 total
includes taxes & fees
25 Dec - 26 Dec
Good Nite Inn - Redwood City
Exterior
DoubleTree by Hilton Hotel Berkeley Marina

DoubleTree by Hilton Hotel Berkeley Marina

DoubleTree by Hilton Hotel Berkeley Marina
4.0 star property
26.4 km from Serra Highlands
8.2 out of 10, Very good, (4000)
"It was a great stay "
United States
Yagnesh
The price is Rp1.879.350
Rp2.164.917 total
includes taxes & fees
4 Jan - 5 Jan 2026
DoubleTree by Hilton Hotel Berkeley Marina
Interior
FOUND Hotel Carlton, Nob Hill

FOUND Hotel Carlton, Nob Hill

FOUND Hotel Carlton, Nob Hill
2.0 star property
14.8 km from Serra Highlands
8.6 out of 10, Excellent, (1130)
"such clean rooms & wonderful staff they are very helpful felt so comfortable in my stay!"
United States
heidi
The price is Rp1.202.985
Rp1.415.854 total
includes taxes & fees
5 Jan - 6 Jan 2026
FOUND Hotel Carlton, Nob Hill
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Serra Highlands

Find the best Serra Highlands areas for the activities you enjoy most.
Union Square featuring a skyscraper and a city

Union Square

Fashion puts on its finest face in one of the country’s largest shopping plazas.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

Fisherman\'s Wharf featuring a bay or harbour

Fisherman's Wharf

This waterfront neighborhood dates back to the gold rush era and is a hub for tourist activities, sea lions and seafood restaurants.

South of Market which includes skyline, a park and cbd

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill showing street scenes and a city

Nob Hill

Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.

Top Serra Highlands Hotel Reviews

Hotel Zoe Fisherman's Wharf

Hotel Zoe Fisherman's Wharf

10/10 Excellent
"nice hotel great location walkable "
GIDEON 6-night trip
Posted 11 hours ago
Hotel Zoe Fisherman's Wharf

Frequently asked questions

What is Serra Highlands like?
Travellers to South San Francisco's Serra Highlands neighbourhood will be sure to enjoy a stay here.
How many hotels will I find in the Serra Highlands area?
Book one of Expedia's 5 hotels and other accommodation options in Serra Highlands and start exploring everything South San Francisco has to offer.
If I need to cancel my hotel reservation in Serra Highlands, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the best deals in Serra Highlands.
What is there to do in this South San Francisco neighbourhood?
Cypress Lawn Memorial Park, Hills of Eternity Memorial Park and Wyatt Earp's Grave are just a few of the places to visit in and around Serra Highlands. While you're out sightseeing, Pet's Rest Cemetery and Serramonte Center are a couple of additional sights to visit in South San Francisco.