Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in South Carolina Lowcountry

Spa

Apart hotel

Our top choices for South Carolina Lowcountry hotels

OYO Hampton South Carolina Hwy 278

Hampton

James

Rp2.143.514 total

includes taxes & fees

12 Apr - 13 Apr

Microtel Inn & Suites by Wyndham Walterboro

Walterboro

Steven

Rp1.807.330 total

includes taxes & fees

13 Apr - 14 Apr

Best Western Plus Bluffton / Hilton Head Hotel

Bluffton

Alexandria

Rp2.393.332 total

includes taxes & fees

19 Apr - 20 Apr

607 Bay Inn Downtown Beaufort

Historic District

Susan

Rp2.898.271 total

includes taxes & fees

4 May - 5 May

Hilton Beachfront Resort & Spa Hilton Head Island

Mid Island

Marcus

Rp4.964.521 total

includes taxes & fees

26 Apr - 27 Apr

Beaufort Inn

Downtown Beaufort

Kristina

Rp4.141.291 total

includes taxes & fees

26 Apr - 27 Apr

Tru by Hilton Beaufort, SC

Beaufort

Chekina

Rp2.078.475 total

includes taxes & fees

13 Apr - 14 Apr

Basic Room, Multiple Beds, Non Smoking | Free WiFi, bed sheets

Simple Rewards Inn

Mid Island

anemaria

Rp1.705.204 total

includes taxes & fees

11 Apr - 12 Apr

Standard Room, 1 King Bed, Non Smoking, Refrigerator | Free WiFi, bed sheets

Motel 6 Walterboro, SC

Walterboro

Bradford

Holiday Inn Express Bluffton at Hilton Head Area by IHG

Bluffton

Blake

Rp2.634.170 total

includes taxes & fees

26 Apr - 27 Apr

Studio Suite, 1 King Bed with Sofa bed | In-room safe, iron/ironing board, WiFi, bed sheets

Palmera Inn and Suites

South End

Patricia

Rp2.293.336 total

includes taxes & fees

20 Apr - 21 Apr

Hilton Garden Inn Hilton Head

Hilton Head Island

Nick

Rp2.453.165 total

includes taxes & fees

19 Apr - 20 Apr

Best Western Sea Island Inn

Downtown Beaufort

Alison

Rp3.276.239 total

includes taxes & fees

27 Apr - 28 Apr

Quality Inn Yemassee - Point South I-95

Yemassee

George

Rp1.227.157 total

includes taxes & fees

14 Apr - 15 Apr

Hampton Inn Hardeeville

Hardeeville

dawn

Rp2.203.081 total

includes taxes & fees

4 May - 5 May

Best Western Plus Hardeeville Inn & Suites

Hardeeville

Ann

Rp1.963.262 total

includes taxes & fees

14 Apr - 15 Apr

City Loft Hotel

Historic District

Jeffrey

Rp3.408.855 total

includes taxes & fees

12 Apr - 13 Apr

Beach House Resort Hilton Head

South End

Danelle

Rp4.296.947 total

includes taxes & fees

22 Apr - 23 Apr

Desk, iron/ironing board, free WiFi, bed sheets

Comfort Inn & Suites Walterboro I-95

Walterboro

James

Rp2.199.103 total

includes taxes & fees

5 May - 6 May

The Westin Hilton Head Island Resort & Spa

Mid Island

Heather

Rp4.318.330 total

includes taxes & fees

22 Apr - 23 Apr

View all properties

Holiday Rentals in South Carolina Lowcountry

Aparthotel

Indoor pool, 2 outdoor pools, pool umbrellas, pool loungers

Bluewater Resort & Marina by Spinnaker Resorts

North End

"Property was very well kept, rooms were very clean and spacious. The location is excellent to Tanger Outlet and many restaurants. Will definitely stay there again. "

Condo

2 outdoor pools, pool umbrellas, pool loungers

Waterside by Spinnaker Resorts

South End

"Waling distance to shops, restaurants and beach. Great rooms, super spacious. Clean comfortable beds and furniture. Pools were top notch!"

Cottage

Fire Pit + Yard: Charming Port Royal Home!

Port Royal

"Amazing little place. 5 minutes from the front gates of Parris Island MCRC. Stayed three days everything we needed."

Condo

Fiddler's Cove 7L by Hilton Head Retreats

Mid Island

"The property was very clean and the beds were so comfortable. We love the pool area and the very short walk to a gorgeous beach. There are so many very good restaurants nearby and lots of shopping. The complex is very quiet and looked after. I would highly recommend this property!"

Condo

Carolina Club by Spinnaker Resorts

South End

"I really enjoyed my stay. I am looking forward to staying again."

Holiday Home

Townhome, 2 Bedrooms | Bathroom | Separate bathtub and shower, jetted bath, free toiletries, hair dryer

Coral Reef Resort

South End

"We loved our stay! No issues at all, everything was clean, functional, pool could use some TLC with cleaning not other then that it was great. We loved the steam sauna, jacuzzi, and we really loved the bike rentals. We will be back!"

Villa

838 Ketch Court at The Sea Pines Resort

Sea Pines

"Our stay in Harbor Town was very enjoyable! You can't beat the location or the views. We walked to the Quarterdeck and CQ's for dinner, and got some shopping in. This is a 1 bedroom, which was perfect for us. It was clean, the bed was comfy, spacious living room, and a small balcony to enjoy coffee or a cocktail overlooking the harbor. FYI, we needed to buy a bar of soap as there was just one tiny round one to share between the shower and the sinks. The kitchen was well stocked with what we...

Condo

Shipyard Resort by Spinnaker Resorts

South End

"We loved the setting among the Egret birds and lovely trees. Very tropical. The pool and beach access was excellent. "

Holiday Home

Montage Palmetto Bluff Residences

Palmetto Bluff

"This was our second visit to Montage Palmetto Bluff and once again it did not disappoint. The hospitality we find here is second to none. Everywhere we went we were greeted with smiling faces. We’d like to give a special shout out to Carmela at the concierge desk who was so incredibly wonderful with our 4 year-old son, Henry. Everything she did and every recommendation she provided enhanced our stay. The natural beauty of this place is beyond compare. We cannot wait to visit again. "

Apartment

Hilton Head Island Studio w/ Patio: Walk to Beach!

Sea Pines

"The unit is small - ideal for a single person or a couple - and is perfectly situated with a beautiful view of the sunrise over a marshy area. It is across the street from the beach and a short walk to the Salty Dog restaurant and nearby shops. "

Condo

Hilton Head Island Beach & Tennis Resort by Hilton Head Retreats

Mid Island

"The beach view is ok , condo had all the basic necessities . One thing I would suggest is the springs of the couch are popping thru the cushions so might be time to replace it . "

See all holiday rentals

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Southeastern United States attractions

Coligny Beach

4.6/5 (2,649 reviews)

If a restful holiday is part of your travel plans, Coligny Beach might be the perfect place to visit during your trip to Hilton Head Island. Wander the seaside and forests while you're in the area.

See properties

Coligny Plaza

4.5/5 (1,957 reviews)

You can enjoy retail therapy at Coligny Plaza during your trip to Hilton Head Island. Wander through the beautiful beaches and seaside in this family-friendly area.

See properties

Learn more about South Carolina Lowcountry

Check out the local area in South Carolina Lowcountry—home to attractions like Highway 21 Drive-In Theater and Beaufort National Cemetery.

See all hotels in South Carolina Lowcountry

Top South Carolina Lowcountry Hotel Reviews

Holiday Inn Express Hilton Head Island by IHG

6/10 Okay

"Internet was decently fast, the reason to staying here is all about location. The location is amazing. "

Hampton Inn Hilton Head

10/10 Excellent

""A hidden gem! Family friendly, minutes away from the beach, cozy, located on a quiet part of the beach, yet still within walking distance of restaurants:) The staff was very friendly and professional, Enjoyed the breakfast , confortable beds and pillows, a nice relaxing pool, anything else we nedeed one text away :) , I loved that. Perfect for a relaxing getaway with family." We definitely will be back. Our roooms were clean and spacious. Highly recommended . Is close to small island airport. And yet , was quite. "