A beach with a pier extending into the ocean, a person standing on the shore, and the sun setting over the water.

South San Diego hotel guide. La Quinta Inn & Suites hotel in South San Diego, California

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
14 Sept - 15 Sept
Tomorrow
15 Sept - 16 Sept
This weekend
18 Sept - 20 Sept
Next weekend
25 Sept - 27 Sept

Our top choices for South San Diego La Quinta Inn & Suites

1. La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista
Chula Vista
United States
Kaye
Rp1.811.291
Rp1.992.420 total
includes taxes & fees
11 Oct - 12 Oct
La Quinta Inn by Wyndham San Diego Chula Vista

2. La Quinta Inn & Suites by Wyndham San Diego Mission Bay

La Quinta Inn & Suites by Wyndham San Diego Mission Bay
Pacific Beach
United States
Virgen
Rp2.056.260
Rp2.364.072 total
includes taxes & fees
1 Oct - 2 Oct
La Quinta Inn & Suites by Wyndham San Diego Mission Bay
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Top South San Diego Hotel Reviews

The Alcala Hotel Mission Valley/Seaworld

The Alcala Hotel Mission Valley/Seaworld

10/10 Excellent
"clean room, king size bed is the best way to go. Breakfast is on point, 2nd time staying here and have not been disappointed!!!"
Alfredo M. 1-night trip
Posted 4 hours ago
The Alcala Hotel Mission Valley/Seaworld
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

10/10 Excellent
"Definitely an amazing hotel for our first visit to San Diego!"
Myra 2-night trip
Posted 5 hours ago
Hard Rock Hotel San Diego
Sheraton San Diego Resort

Sheraton San Diego Resort

10/10 Excellent
"Clean property , nice pool"
Kayleen 1-night trip
Posted 8 hours ago
Sheraton San Diego Resort
The Dana on Mission Bay

The Dana on Mission Bay

10/10 Excellent
"My wife and I stayed at the Dana and we had a great time and the staff was so friendly. The area is close by to Mission Beach and the hotel has a lot to offer. We felt at home and will come back for sure!"
Jerron Felix 3-night trip
Posted 11 hours ago
The Dana on Mission Bay
Gaylord Pacific Resort & Convention Center

Gaylord Pacific Resort & Convention Center

8/10 Good
"My husband and I took our three toddlers. The hotel was amazing and the kids had a blast! Although we wished they had a pizza place or something quick to offer, instead of just a restaurant or marketplace. We had to get outside food. Which wasn’t too bad, because it wasn’t too far from the hotel. But would have been nice to have something that was available late in the hotel. Since the kitchen at the pool area ends at 7."
Yessenia 2-night trip
Posted 11 hours ago
Gaylord Pacific Resort & Convention Center
Best Western Seven Seas

Best Western Seven Seas

8/10 Good
"A great quick place to catch some sleep"
Leslie 4-night trip
Posted 13 hours ago
Best Western Seven Seas
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

10/10 Excellent
"Everyone from valet to bell hops to check in was great. We always get a corner room the views are great. Didn’t use the pool this trip but highly recommend the breakfast buffet all the staff and food are awesome. 👏"
Bob 2-night trip
Posted 14 hours ago
Manchester Grand Hyatt San Diego

Explore a world of travel with Expedia