Photo by Bill Dillard

Find hotels in Southeast Missouri, MO from Rp1.003.635
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Southeast Missouri
Family friendly
Apartment
Check prices for these dates
Our top choices for Southeast Missouri hotels

Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (897 reviews)
The price is Rp1.922.360
Rp2.171.786 total
includes taxes & fees
4 Jun - 5 Jun

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,000 reviews)
The price is Rp1.577.435
Rp1.667.743 total
includes taxes & fees
10 Jun - 11 Jun

The Farmstead Hotel
The Farmstead HotelCaruthersville
8.6 out of 10, Excellent, (549 reviews)
The price is Rp1.660.220
Rp1.888.085 total
includes taxes & fees
1 Jun - 2 Jun

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (764 reviews)
The price is Rp1.624.062
Rp1.757.640 total
includes taxes & fees
21 May - 22 May

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
The price is Rp1.928.190
Rp2.175.268 total
includes taxes & fees
31 May - 1 Jun

Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MOPoplar Bluff
8.0 out of 10, Very good, (1,001 reviews)
The price is Rp1.227.030
Rp1.374.274 total
includes taxes & fees
16 May - 17 May

Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar BluffPoplar Bluff
9.2 out of 10, Wonderful, (1,001 reviews)
The price is Rp1.922.185
Rp2.171.588 total
includes taxes & fees
28 May - 29 May

Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (182 reviews)
The price is Rp1.624.062
Rp1.832.169 total
includes taxes & fees
7 Jun - 8 Jun

Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
The price is Rp1.735.196
Rp1.957.543 total
includes taxes & fees
14 Jun - 15 Jun

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,002 reviews)
The price is Rp1.752.725
Rp1.977.319 total
includes taxes & fees
7 Jun - 8 Jun

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
La Quinta Inn & Suites by Wyndham Festus - St. Louis SouthFestus
8.0 out of 10, Very good, (980 reviews)
The price is Rp1.773.058
Rp2.027.492 total
includes taxes & fees
20 May - 21 May

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,000 reviews)
The price is Rp1.945.544
Rp2.236.889 total
includes taxes & fees
31 May - 1 Jun

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (560 reviews)
The price is Rp1.782.349
Rp2.018.064 total
includes taxes & fees
14 Jun - 15 Jun

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.0 out of 10, Wonderful, (1,000 reviews)
The price is Rp1.261.913
Rp1.423.614 total
includes taxes & fees
14 Jun - 15 Jun

Super 8 by Wyndham Potosi
Super 8 by Wyndham PotosiPotosi
7.0 out of 10, Good, (396 reviews)
The price is Rp1.046.113
Rp1.142.618 total
includes taxes & fees
30 May - 31 May

Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (836 reviews)
The price is Rp1.710.480
Rp1.915.310 total
includes taxes & fees
8 Jun - 9 Jun

Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MOFarmington
8.0 out of 10, Very good, (1,001 reviews)
The price is Rp1.009.670
Rp1.099.025 total
includes taxes & fees
14 Jun - 15 Jun

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (77 reviews)
The price is Rp1.922.360
Rp2.176.591 total
includes taxes & fees
11 Jun - 12 Jun

Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
8.4 out of 10, Very good, (1,010 reviews)
The price is Rp1.579.012
Rp1.799.679 total
includes taxes & fees
20 May - 21 May

New Orleans Inn Portageville
New Orleans Inn PortagevillePortageville
8.0 out of 10, Very good, (764 reviews)
The price is Rp990.889
Rp1.069.912 total
includes taxes & fees
31 May - 1 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Southeast Missouri
Cabin

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (66 reviews)
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Southeast Missouri attractions
Learn more about Southeast Missouri
Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to K Bridge Recreation Area.

Photo by Bill Dillard
Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
10/10 Excellent
More cheap stays in Southeast Missouri

Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
The price is Rp1.009.670 per night from 14 Jun to 15 Jun
Rp1.009.670
Rp1.099.025 total
14 Jun - 15 Jun
includes taxes & fees
8/10 Very Good! (1,001 reviews)







































































































