Upstate South Carolina Holidays

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Where to stay in Upstate South Carolina

Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
A pedestrian bridge with colorful lights, surrounded by trees and a distant building.

Greenville Downtown

3 out of top 10 points of interest in this area

The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.

Find hotels in Greenville Downtown

Top hotels in Upstate South Carolina

Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
The price is Rp2.295.702 per night from 26 Jul to 27 Jul
Rp2.295.702
Rp2.594.244 total
26 Jul - 27 Jul
includes taxes & fees
8.4/10 Very good! (1,000 reviews)
"Be prepared to pay for parking and breakfast. Also your room will not be ready for check in. Check your sheets for hair"

Reviewed on 1 Jul 2026

Hilton Greenville
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
The price is Rp5.188.128 per night from 5 Jul to 6 Jul
Rp5.188.128
Rp5.862.586 total
5 Jul - 6 Jul
includes taxes & fees
9.6/10 Exceptional! (516 reviews)
"We spent our honeymoon here and it was absolutely breathtaking. What a fantastic experience and we highly recommend that anybody looking for acquaint and beautiful place to stay, this is it. 👍👍 two thumbs up."

Reviewed on 29 Jun 2026

Grand Bohemian Lodge Greenville, Autograph Collection
Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5
220 N Main St Greenville SC
Fully refundableReserve now, pay when you stay
The price is Rp3.195.456 per night from 14 Jul to 15 Jul
Rp3.195.456
Rp3.620.452 total
14 Jul - 15 Jul
includes taxes & fees
8.8/10 Excellent! (1,000 reviews)
"Great hotel overall. The night we stayed they were booked to capacity and our AC wasn’t working below 75. After being in the heat for a concert, it was really inconvenient."

Reviewed on 30 Jun 2026

Hyatt Regency Greenville
See all 3,085 properties in Upstate South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)
Take a campus tour or just explore the area of Clemson University during your travels in Clemson. Experience the area's theatre scene or attend a football match.
See properties

What to do in Upstate South Carolina

Greenville: Saturday Morning Breakfast Tour

Greenville: Saturday Morning Breakfast Tour

Rp1.607.310
per adult
Greenville: Saturday Morning Breakfast Tour
Greenville: 2-Hour Dessert Tour

Greenville: 2-Hour Dessert Tour

Rp1.607.310
per adult
Greenville: 2-Hour Dessert Tour
Gorgeous loop around Swan Lake at Furman University.

Guided E-Bike Tour in Greenville South Carolina with Brunch

Rp1.874.123
per adult
Guided E-Bike Tour in Greenville South Carolina with Brunch
See all activities in Upstate South Carolina

Frequently asked questions

How much does a Upstate South Carolina holiday package cost?
Our Upstate South Carolina holiday packages, which begin from just , are an awesome way to save loads of cash. Choose your preferred flights, hotels and rental cars to create your dream getaway.
How do I get a cheap travel package to Upstate South Carolina?
You'll save piles of cash if you bundle your hotels, flights and car rentals into a Upstate South Carolina holiday package. Sometimes cheap packages mean fewer options. But that's not the case with Expedia. We offer more than 550 partner airlines and 1,000,000 hotels across the world, so you'll always have plenty of options to choose from. Eager to save even more? Add some fun activities to your package deal to unlock even bigger bargains! After all, travel is about more than simply getting to your destination.
Where should I stay in Upstate South Carolina?
Falls Park on the Reedy is one of the main things that attracts visitors to Upstate South Carolina, so it makes perfect sense that many choose to book their hotel in Greenville.
What are the top hotels in Upstate South Carolina?
Best Western Plus Greenville I-385 Inn & Suites and Comfort Inn Greenville - Haywood Mall know how to make their guests feel at home in Greenville. If you also plan to explore Seneca, take a look at Quality Inn Seneca US-123 and Tru by Hilton Seneca Clemson. Both are very popular with travellers.
How far in advance should I book my Upstate South Carolina holiday?
It can be hard to know exactly when the best time is to book your Upstate South Carolina holiday. But typically the earlier you book, the more affordable the prices. Sometimes, you can lock in your flights and hotels up to 12 months prior to departure. If you're considering a last-minute getaway, no need to fret! There are plenty of fantastic bargains announced on Expedia every single day.
What does an Expedia Upstate South Carolina travel package include?
That depends on what sort of trip you have in mind. Upstate South Carolina holiday deals can include car rentals, flights and hotels. You can mix and match to find the travel package that suits your budget and style. You can also add on activities and experiences after you've booked to score even bigger discounts.
What should I know before booking a Upstate South Carolina travel package?
An Expedia travel package can be customized for your budget and is a fantastic way to make your budget go further. What you include is totally up to you. Rental cars, hotels and flights — decide on a combination that suits your style.
Can I choose my airline with a Upstate South Carolina Expedia holiday package?
Yes, of course. Expedia has access to more than 550 airline partners globally, so go with the carrier that best fits your budget and travel needs.
If I'm not able to travel, can I cancel my Upstate South Carolina holiday package?
If your travel plans in Upstate South Carolina have been upended, it's comforting to know that you can cancel your booking. If you made your booking in the last 24 hours, you may be eligible for a refund. If your booking was made more than 24 hours ago, your airline, hotel or car rental company may impose fees. To learn more, check our Customer Service Portal.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.