Upstate South Carolina Holidays

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Where to stay in Upstate South Carolina

Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
A pedestrian bridge with colorful lights, surrounded by trees and a distant building.

Greenville Downtown

3 out of top 10 points of interest in this area

The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.

Find hotels in Greenville Downtown

Top hotels in Upstate South Carolina

Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
The price is Rp2.291.865 per night from 5 Jul to 6 Jul
Rp2.291.865
Rp2.589.807 total
5 Jul - 6 Jul
includes taxes & fees
8.4/10 Very good! (1,001 reviews)
"Wonderful business stay!"

Reviewed on 18 Jun 2026

Hilton Greenville
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
The price is Rp4.821.018 per night from 5 Jul to 6 Jul
Rp4.821.018
Rp5.447.751 total
5 Jul - 6 Jul
includes taxes & fees
9.6/10 Exceptional! (513 reviews)
"The decorations were fantastic!"

Reviewed on 19 Jun 2026

Grand Bohemian Lodge Greenville, Autograph Collection
Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5
220 N Main St Greenville SC
Fully refundableReserve now, pay when you stay
The price is Rp2.726.832 per night from 2 Jul to 3 Jul
Rp2.726.832
Rp3.089.501 total
2 Jul - 3 Jul
includes taxes & fees
8.8/10 Excellent! (1,004 reviews)
"Great location"

Reviewed on 27 Jun 2026

Hyatt Regency Greenville
See all 3,019 properties in Upstate South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/5 (1,439 reviews)
Take a campus tour or just explore the area of Clemson University during your travels in Clemson. Experience the area's theatre scene or attend a football match.
See properties

What to do in Upstate South Carolina

Greenville: Saturday Morning Breakfast Tour

Greenville: Saturday Morning Breakfast Tour

Rp1.607.310
per adult
Greenville: Saturday Morning Breakfast Tour
Greenville: 2-Hour Dessert Tour

Greenville: 2-Hour Dessert Tour

Rp1.607.310
per adult
Greenville: 2-Hour Dessert Tour
Gorgeous loop around Swan Lake at Furman University.

Guided E-Bike Tour in Greenville South Carolina with Brunch

Rp1.874.123
per adult
Guided E-Bike Tour in Greenville South Carolina with Brunch
See all activities in Upstate South Carolina

Frequently asked questions

Can I cancel my flight booking to Upstate South Carolina due to COVID-19?
Head to our Customer Service Portal for important information about changing or cancelling flights due to COVID-19. Make sure you also read through the terms and conditions of your chosen airline before booking your fare to Upstate South Carolina.
What's the best way to find cheap flights to Upstate South Carolina that have flexible change policies?
We understand that travel plans can change in the blink of an eye, so reserving a flexible ticket with Expedia is a sensible idea. Simply tick the "No change fee" box under the "Flexible change policies" filter. Your low-cost, flexible flight to Upstate South Carolina is just a few clicks away.
What are some of the general tips for travellers to Upstate South Carolina during the COVID-19 outbreak?
COVID-19 has affected how the world works in endless ways, and travel has changed with it. These tips will help you navigate these new challenges and prepare you for your trip to Upstate South Carolina:
  • Before booking anything, see if any travel bans or restrictions apply — in both your origin and destination. Get up-to-date information by reviewing government and travel websites.
  • Wear a face mask even during airport screening. A TSA employee will require you to lower your mask temporarily to verify your identity.
  • You're no longer required to hand your boarding pass (paper or electronic) directly to a TSA officer. Rather, place your pass on the scanner and then hold it up for inspection.
  • One container of liquid hand sanitizer is now allowed in your carry-on luggage. It must not be larger than 12 oz (350 ml), and you'll need to remove it from your bag for screening.
  • To reduce handling during screening, place items such as your phone and loose change into your carry-on rather than the bins.
  • Separate any food you're carrying for X-ray screening. Placing it in a clear plastic bag and into a bin reduces the need for a TSA officer to touch and inspect your belongings.

Which airlines fly to Upstate South Carolina?
Secure your ticket with American Airlines and then start piecing together your Upstate South Carolina itinerary. This leading carrier offers 19932 flights each month to Charlotte-Douglas Intl. Airport (CLT), a key gateway.
How can I find cheap tickets to Upstate South Carolina?
You'll always nab a fabulous deal with Expedia, but our "flexible dates" feature makes it that much easier. Enter your preferred flight date, then check the flexible dates box above to see a list of prices for nearby days. was the lowest price for a flight to Upstate South Carolina in the last seven days.
How much is a flight to Upstate South Carolina?
One-way trips departing from () sold for as little as in the last seven days. During this period, the price of a round-trip fare to Upstate South Carolina ranged between and . If you find a bargain ticket, book as fast as you can — these prices don't stick around.
What are the most popular airports to fly into in Upstate South Carolina?
Book your flight to Charlotte-Douglas Intl. Airport (CLT) and experience everything that Upstate South Carolina has to offer. As the region's primary entry point, about 21666 flights touch down here every month.
When is the cheapest time to fly to Upstate South Carolina?
If you'd prefer to spend your hard-earned holiday money experiencing the delights of Upstate South Carolina rather than on your trip there, leave early in the week. The most affordable day to travel is normally Tuesday, with Monday coming in second. With many people travelling over the weekend, Saturday often has the costliest fares.
How much is a plane ticket to Upstate South Carolina?
Plane fares ranged anywhere from to in the last seven days. When you're ready to book, we'll help you find a low-cost flight to Upstate South Carolina.
Which airlines with flights to Upstate South Carolina employ COVID-19 cleanliness policies?
In response to the global COVID-19 pandemic, many airlines have introduced new rules and standards to help everybody get back in the skies. These carriers include:
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Delta - this airline is known for electrostatic cleaning and cleaning with disinfectant.
  • United Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.

How long is a flight to Upstate South Carolina?
It depends on where in the States you're travelling from. This list of top domestic routes and their average flight times will give you an idea of how long it'll take to reach Upstate South Carolina:
  • Atlanta, GA Airport (ATL-Hartsfield-Jackson Atlanta Intl.) to Charlotte-Douglas Intl. Airport (CLT) - 1 hour and 20 minutes
  • Orlando, FL Airport (MCO-Orlando Intl.) to Charlotte-Douglas Intl. Airport (CLT) - 1 hour and 49 minutes
  • New York, NY Airport (LGA-LaGuardia) to Charlotte-Douglas Intl. Airport (CLT) - 2 hours and 12 minutes

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.