The Best Hotels in Uptown, Beaufort - 2026 Updated Prices

A sign welcoming visitors to Downtown Beaufort, established in 1711, with palm trees and a bridge over water.

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Our top choices for Uptown hotels

A modern hotel with a flat roof, large windows, and a well-lit entrance.

1. SpringHill Suites by Marriott Beaufort

2.1 km from Uptown

Michelle

Rp2.322.641 total

includes taxes & fees

4 Oct - 5 Oct

A modern hotel building with a prominent 'tru by Hilton' sign, large windows, and a parking lot.

2. Tru by Hilton Beaufort, SC

4.6 km from Uptown

Curtis

Rp1.920.707 total

includes taxes & fees

31 Oct - 1 Nov

An outdoor patio with wicker furniture, a central fire pit, and string lights.

3. Beaufort Inn

Downtown Beaufort, 0.9 km from Uptown

James

Rp3.607.769 total

includes taxes & fees

1 Nov - 2 Nov

A modern kitchen with a built-in island, a flat-screen TV, and a coffee station.

4. Best Western Sea Island Inn

The Bluff, 0.9 km from Uptown

Franco

Rp3.290.867 total

includes taxes & fees

11 Oct - 12 Oct

A modern hotel lobby with a long bar, seating area, and a view of the kitchen in the background.

5. Hampton Inn Beaufort

2.5 km from Uptown

Kimberly

Rp2.208.478 total

includes taxes & fees

12 Oct - 13 Oct

An outdoor lounge area with multiple seating options, including sofas and benches, under a covered structure with a grid-like ceiling.

6. Home2 Suites BY Hilton Beaufort, SC

4.7 km from Uptown

Edgardo

Rp2.082.109 total

includes taxes & fees

1 Nov - 2 Nov

A gym with cardio machines, weightlifting equipment, and a large exercise ball.

7. City Loft Hotel

The Old Point, 1 km from Uptown

Jim

Rp3.073.759 total

includes taxes & fees

5 Oct - 6 Oct

A two-story white colonial-style building with a central entrance, columns, and a balcony on the upper floor.

8. Anchorage 1770

The Bluff, 0.8 km from Uptown

Patricia

Rp5.184.250 total

includes taxes & fees

4 Oct - 5 Oct

A hotel lobby with a bar area, seating arrangements, and a patterned carpet.

9. Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG

2 km from Uptown

Shelia R

Rp2.165.175 total

includes taxes & fees

4 Oct - 5 Oct

A historic building with a balcony, large trees, and an American flag.

10. Rhett House Inn

The Bluff, 0.7 km from Uptown

Norman

Rp4.394.793 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a large bed, a nightstand with a lamp, a wall-mounted air conditioner, and framed pictures on the wall.

11. Sleep Inn Beaufort near MCAS

3.3 km from Uptown

Zinmar

Rp1.656.358 total

includes taxes & fees

30 Oct - 31 Oct

A modern living room with a fireplace, a flat-screen TV, and a bookshelf.

12. Country Inn & Suites by Radisson, Beaufort West, SC

2.9 km from Uptown

Erica

Rp1.930.941 total

includes taxes & fees

12 Oct - 13 Oct

A hotel with a prominent "Hilton Garden Inn" sign, featuring a classic architectural style with brick facade and large windows.

13. Hilton Garden Inn Beaufort

1.4 km from Uptown

Cheryl

Rp2.123.840 total

includes taxes & fees

1 Nov - 2 Nov

A pool area with a table set with a bottle, glasses, and roses.

14. Comfort Suites near MCAS Beaufort

3.8 km from Uptown

Stephen

Rp1.860.475 total

includes taxes & fees

1 Nov - 2 Nov

15. Circa 1785

The Old Commons, 0.5 km from Uptown

Rebecca

Rp4.310.665 total

includes taxes & fees

12 Oct - 13 Oct

A balcony with wicker chairs and a table, surrounded by columns and a brick wall.

16. 607 Bay Inn Downtown Beaufort

The Old Point, 1.1 km from Uptown

William

Rp5.080.679 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, white pillows, and a wall with a blue circuit board design.

17. Oasis Inn

2.2 km from Uptown

Steven

Rp2.164.977 total

includes taxes & fees

4 Oct - 5 Oct

A grassy area with a white picket fence and a building in the background.

18. Howard Johnson by Wyndham Beaufort/Parris Island

4.7 km from Uptown

Erica

Rp1.338.472 total

includes taxes & fees

1 Nov - 2 Nov

A marina with boats docked at wooden piers, calm water, and a clear sky.

19. Super 8 by Wyndham Port Royal/Beaufort

4.7 km from Uptown

John David Moore

Rp1.254.817 total

includes taxes & fees

12 Oct - 13 Oct

A two-story building with a covered entrance and a flagpole.

20. America's Best Inn and Suites Beaufort

2.9 km from Uptown

Jeffrey

Rp1.574.475 total

includes taxes & fees

28 Oct - 29 Oct

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Where to stay in Uptown

Find the best Uptown areas for the activities you enjoy most.

An aerial view of a coastal town with a marina, dense greenery, and a bridge connecting to the mainland.

Historic District

While visiting Historic District, you might make a stop by sights like USCB Center for the Arts and Bay Street.

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A paved path flanked by trees and greenery, leading into the distance.

Downtown Beaufort

While visiting Downtown Beaufort, you might make a stop by sights like Henry C. Chambers Waterfront Park and Bay Street.

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A wooden bridge over a river with a clear sky and distant land.

Northwest Quadrant

While there might not be top attractions in Northwest Quadrant, you can explore the larger area and discover places like Beaufort National Cemetery and USCB Center for the Arts.

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A park with a bench, trees, and flowering bushes.

Habersham

If you're looking for some top things to see and do in Habersham and surrounding area, you can visit Highway 21 Drive-In Theater and Ocean Creek.

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An aerial view of a coastal town with dense greenery, a marina with boats, and residential buildings.

Historic Downtown

If you're spending some time in Historic Downtown, Henry C. Chambers Waterfront Park and Bay Street are top sights worth seeing.

See properties

Top Uptown Hotel Reviews

City Loft Hotel

10/10 Excellent

"This was our second time staying here. We love Beaufort and love this Boutique motel. The location is wonderful and the staff is so helpful. Bonus is the Cafe. We love the coffee. We will always stay here."

The Westin Hilton Head Island Resort & Spa

8/10 Good

"Nice resort on a beautiful island. Great location for golfers. Unfortunately the weather didn't cooperate and most of our late-September visit was too cold to swim in the ocean. The heated pool may have been heated technically, but was still pretty cool to swim in. That left everyone trying to fit in the hot tub, which became a bit crowded. The property is in very good condition generally, although the elevator closest to the pool didn't work for us a couple of times and we had to take the stairs. As with most resorts, you are nickel and dimed for a lot... valet parking, self parking, daily resort fees, charges for chairs near the pool and cabanas. It seems like when you are paying these per-night fees that some of that would be included, especially in the off season. We might come back, but if so it would certainly be in the summer when we could swim in the ocean."

Hampton Inn Beaufort

10/10 Excellent

"We had a wonderful stay and couldn’t have been happier with our experience. From the moment we arrived, the staff was welcoming, friendly, and extremely helpful. The hotel was clean, comfortable, and well maintained, and everything we needed was easily accessible. What really stood out was the level of customer service. Everyone we interacted with was professional and genuinely seemed to care about making sure we had a great stay. Our room was clean and comfortable, and the overall atmosphere of the hotel made it easy to relax and enjoy our time there. We would absolutely stay here again and would highly recommend this hotel to anyone visiting the area. Thank you to the entire staff for making our stay such a positive experience!"

Frequently asked questions

What's it like in Uptown?

Travellers will be sure to enjoy their time in Beaufort's Uptown neighbourhood.

How many hotels will I be able to find in Uptown?

If you're searching for places to stay in Beaufort, choose from one of Expedia's 12 hotels and other accommodation options in Uptown.

If I need to cancel my hotel reservation in Uptown, will I receive a refund?

Yes, the majority of hotel bookings are refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then use the "fully refundable" filter to view the top deals on offer in Uptown.

What is there to do in this Beaufort neighbourhood?

A few places to visit in the area around Uptown include Beaufort National Cemetery, USCB Center for the Arts and St. Helena's Episcopal Church. Beaufort History Museum and Henry C. Chambers Waterfront Park are also worth a visit when you're out sightseeing in Beaufort.

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Our top choices for Uptown hotels

1. SpringHill Suites by Marriott Beaufort

2. Tru by Hilton Beaufort, SC

3. Beaufort Inn

4. Best Western Sea Island Inn

5. Hampton Inn Beaufort

6. Home2 Suites BY Hilton Beaufort, SC

7. City Loft Hotel

8. Anchorage 1770

9. Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG

10. Rhett House Inn

11. Sleep Inn Beaufort near MCAS

12. Country Inn & Suites by Radisson, Beaufort West, SC

13. Hilton Garden Inn Beaufort

14. Comfort Suites near MCAS Beaufort

15. Circa 1785

16. 607 Bay Inn Downtown Beaufort

17. Oasis Inn

18. Howard Johnson by Wyndham Beaufort/Parris Island

19. Super 8 by Wyndham Port Royal/Beaufort

20. America's Best Inn and Suites Beaufort

Where to stay in Uptown

Historic District

Downtown Beaufort

Northwest Quadrant

Habersham

Historic Downtown

Top Uptown Hotel Reviews

City Loft Hotel

Frequently asked questions

Explore a world of travel with Expedia