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Check prices for these dates

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25 Jan - 26 Jan
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26 Jan - 27 Jan
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30 Jan - 1 Feb
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6 Feb - 8 Feb

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Our top choices for Sioux Empire Medical Museum hotels

Interior detail

Hotel On Phillips

Hotel On Phillips
2.5 star property
Downtown Sioux Falls, 1.9 km from Sioux Empire Medical Museum
9.6 out of 10, Exceptional, (1,345 reviews)
"Nice place to stay"
United States
Andy
Hotel On Phillips
Terrace/patio

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
3.0 star property
University Heights, 0.2 km from Sioux Empire Medical Museum
9.4 out of 10, Exceptional, (600 reviews)
"Clean room | Breakfast Great | Wonderful and Helpful Staff"
United States
Natalie
The price is Rp1.973.827
Rp2.198.928 total
includes taxes & fees
22 Feb - 23 Feb
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
Exterior detail

Clubhouse Hotel Suites Sioux Falls

Clubhouse Hotel Suites Sioux Falls
3.0 star property
Mall District, 2.8 km from Sioux Empire Medical Museum
9.6 out of 10, Exceptional, (1,010 reviews)
"The stay was fantastic!"
United States
Cleo
Clubhouse Hotel Suites Sioux Falls
Meeting facility

Canopy By Hilton Sioux Falls Downtown

Canopy By Hilton Sioux Falls Downtown
4.0 star property
Downtown Sioux Falls, 2.5 km from Sioux Empire Medical Museum
9.4 out of 10, Exceptional, (171 reviews)
"Room was clean and the beds were pretty comfortable. The hotel is in a great location. Only issue, it’s way to close to Smithfield pork processing plant."
United States
Brett
The price is Rp2.275.746
Rp2.597.414 total
includes taxes & fees
8 Feb - 9 Feb
Canopy By Hilton Sioux Falls Downtown
Exterior

Hampton Inn Sioux Falls

Hampton Inn Sioux Falls
2.5 star property
Mall District, 3.1 km from Sioux Empire Medical Museum
9.2 out of 10, Wonderful, (1,004 reviews)
"It was a very nice stay. "
United States
Lenore
The price is Rp1.917.144
Rp2.136.747 total
includes taxes & fees
1 Feb - 2 Feb
Hampton Inn Sioux Falls
Meeting facility

Hilton Garden Inn Sioux Falls Downtown

Hilton Garden Inn Sioux Falls Downtown
3.0 star property
Downtown Sioux Falls, 2.1 km from Sioux Empire Medical Museum
8.8 out of 10, Excellent, (896 reviews)
"Friendly front desk staff, clean room, great location, safe "
United States
Hannah
The price is Rp1.917.144
Rp2.204.027 total
includes taxes & fees
1 Feb - 2 Feb
Hilton Garden Inn Sioux Falls Downtown
Porch

Historic Victorian Inn

Historic Victorian Inn
3.0 star property
Cathedral, 1.5 km from Sioux Empire Medical Museum
8.8 out of 10, Excellent, (56 reviews)
"It was a great place to stay and super interesting."
United States
Kathy
The price is Rp1.747.496
Rp2.192.854 total
includes taxes & fees
21 Feb - 22 Feb
Historic Victorian Inn
Exterior

Holiday Inn Sioux Falls-City Centre by IHG

Holiday Inn Sioux Falls-City Centre by IHG
3.0 star property
Downtown Sioux Falls, 1.9 km from Sioux Empire Medical Museum
8.6 out of 10, Excellent, (1,007 reviews)
"Beds and pillows were comfortable"
United States
Lori
The price is Rp1.530.620
Rp1.712.781 total
includes taxes & fees
8 Feb - 9 Feb
Holiday Inn Sioux Falls-City Centre by IHG
Exterior

Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG

Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG
2.5 star property
Mall District, 3.1 km from Sioux Empire Medical Museum
8.8 out of 10, Excellent, (1,000 reviews)
"The breakfast was amazing and plenty of options with cold food and hot. The staff were great too and so was our room. "
United States
JACKIE
The price is Rp1.799.740
Rp2.007.956 total
includes taxes & fees
1 Feb - 2 Feb
Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG
Exterior

Country Inn & Suites by Radisson, Sioux Falls

Country Inn & Suites by Radisson, Sioux Falls
3.0 star property
Downtown Sioux Falls, 2 km from Sioux Empire Medical Museum
8.4 out of 10, Very good, (1,187 reviews)
"Staff was awesome and the room was nice and clean beds were comfortable. The breakfast was great."
United States
Debra
The price is Rp1.369.266
Rp1.535.725 total
includes taxes & fees
22 Feb - 23 Feb
Country Inn & Suites by Radisson, Sioux Falls
Lobby

Sheraton Sioux Falls Hotel & Convention Center

Sheraton Sioux Falls Hotel & Convention Center
4.0 star property
Northwest Sioux Falls, 2.9 km from Sioux Empire Medical Museum
8.6 out of 10, Excellent, (1,003 reviews)
"Clean and friendly "
United States
Eddie
The price is Rp1.772.828
Rp1.978.433 total
includes taxes & fees
8 Feb - 9 Feb
Sheraton Sioux Falls Hotel & Convention Center
Suite 2 Queens, Recliner, Pullout Sofa | Free WiFi, bed sheets

The Center Inn

The Center Inn
2.5 star property
All Saints, 2.4 km from Sioux Empire Medical Museum
8.4 out of 10, Very good, (717 reviews)
"Room and staff were great. "
United States
Annette
The Center Inn
Basic Studio, 1 King Bed | Desk, free WiFi, wheelchair access

Valley Inn

Valley Inn
2.5 star property
University Heights, 0.2 km from Sioux Empire Medical Museum
7.8 out of 10, Good, (1,001 reviews)
"Clean room Friendliness Great location for us "
United States
Rhonda or doug
Valley Inn
3 indoor pools, open 9:00 AM to 10:00 PM, pool loungers

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
3.0 star property
Northwest Sioux Falls, 2.9 km from Sioux Empire Medical Museum
7.8 out of 10, Good, (1,497 reviews)
"Great pool! And lifeguards that let your kids be kids!"
United States
Jordan
The price is Rp1.080.517
Rp1.218.967 total
includes taxes & fees
29 Jan - 30 Jan
Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
Double Room, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout curtains

Highpoint Hotel

Highpoint Hotel
3.0 star property
University Heights, 0.2 km from Sioux Empire Medical Museum
10.0 out of 10, Exceptional, (2 reviews)
"Excellent staff. "
United States
Peter
The price is Rp1.984.760
Rp2.210.922 total
includes taxes & fees
4 Feb - 5 Feb
Highpoint Hotel
Pool

Ramada by Wyndham Sioux Falls Arpt & Suites

Ramada by Wyndham Sioux Falls Arpt & Suites
2.0 star property
Northwest Sioux Falls, 3 km from Sioux Empire Medical Museum
7.2 out of 10, Good, (53 reviews)
"Very friendly at check in. Great service at bar."
United States
Chris
Ramada by Wyndham Sioux Falls Arpt & Suites
50-inch flat-screen TV with cable channels, fireplace, Netflix

Historic Twin Tudors Inn

Historic Twin Tudors Inn
3.0 star property
1.4 km from Sioux Empire Medical Museum
8.8 out of 10, Excellent, (3 reviews)
"Lovely place! Wish we could have stayed longer. Steve was attentive and helpful. "
United States
Anonymous traveller
The price is Rp4.526.262
Rp5.132.668 total
includes taxes & fees
27 Jan - 28 Jan
Historic Twin Tudors Inn
Lobby

Ramada by Wyndham Sioux Falls

Ramada by Wyndham Sioux Falls
2.0 star property
2.6 km from Sioux Empire Medical Museum
5.6 out of 10, (1,001 reviews)
"Good room for the price."
United States
Michael
The price is Rp829.226
Rp943.301 total
includes taxes & fees
2 Feb - 3 Feb
Ramada by Wyndham Sioux Falls
Terrace/patio

Hyatt Place Sioux Falls South

Hyatt Place Sioux Falls South
3.0 star property
Mall District, 3.7 km from Sioux Empire Medical Museum
9.4 out of 10, Exceptional, (1,003 reviews)
"Great stay!"
United States
Nick
The price is Rp1.984.760
Rp2.210.922 total
includes taxes & fees
1 Feb - 2 Feb
Hyatt Place Sioux Falls South
Exterior

Holiday Inn & Suites Sioux Falls - Airport by IHG

Holiday Inn & Suites Sioux Falls - Airport by IHG
3.0 star property
Northwest Sioux Falls, 3.4 km from Sioux Empire Medical Museum
9.2 out of 10, Wonderful, (852 reviews)
"Clean Room. Beautiful pool and hot tub area. Great location. "
United States
Carissa
The price is Rp1.799.740
Rp2.007.972 total
includes taxes & fees
22 Feb - 23 Feb
Holiday Inn & Suites Sioux Falls - Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Sioux Empire Medical Museum Hotel Reviews

Highpoint Hotel

Highpoint Hotel

10/10 Excellent
"Excellent staff. "
Peter 1-night trip
Posted 1 day ago
Highpoint Hotel

Hotels near other Sioux Empire Medical Museum attractions

Great Plains Zoo

4.3/5 (74 reviews)
Why not meet the animals who live at Great Plains Zoo during your holiday in Sioux Falls? Attend a sporting event or discover the area's beautiful waterfalls.
See properties

University of Sioux Falls

4.1/5 (170 reviews)
Explore the campus of University of Sioux Falls during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.
See properties

Frequently asked questions

What's the area like around Sioux Empire Medical Museum?
Sioux Empire Medical Museum is located in a welcoming area of Sioux Falls known for its beautiful waterfalls and sporting events. If you're looking for a convenient place to stay, take a look at the 127 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Sioux Empire Medical Museum?
Adjacent to Sioux Empire Medical Museum, Home2 Suites By Hilton Sioux Falls/Sanford Medical Center is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. Other good choices within a few miles include Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr and Hotel On Phillips.
How many hotels are there close to Sioux Empire Medical Museum?
Expedia has 127 hotels and other accommodation options within a mile from Sioux Empire Medical Museum.
If I need to cancel the hotel reservation for my stay near Sioux Empire Medical Museum, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then use the "fully refundable" filter to view the best options available near Sioux Empire Medical Museum.
What can I see and do near Sioux Empire Medical Museum?
Washington Pavilion of Arts and Science, Center for Western Studies and Old Courthouse Museum feature a variety of fascinating exhibits to see while you're in town. Learn about local history at St. Joseph Cathedral and Pettigrew Home and Museum. You can wander around Falls Park, Sherman Park or Fawick Park if you want a dose of fresh air.