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12 Nov - 13 Nov
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13 Nov - 14 Nov
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Our top choices for National Medical Center (Siglo XXI) hotels

A room with a wooden floor, a blue chair, a wooden cabinet, and a door leading to a balcony with a metal railing and greenery.

1. NaNa Vida CDMX

NaNa Vida CDMX
4.0 star property
Roma Norte, 0.9 km from National Medical Center (Siglo XXI)
10.0 out of 10, Exceptional, (475 reviews)
"Staff was great and great location"
United States
edward
The price is Rp1.715.757
Rp2.050.331 total
includes taxes & fees
13 Dec - 14 Dec
NaNa Vida CDMX
A building with ornate tiled facades, arched windows, and a balcony with a wrought iron railing.

2. Casa Talavera by Tasman

Casa Talavera by Tasman
2.5 star property
Roma Norte, 1.5 km from National Medical Center (Siglo XXI)
10.0 out of 10, Exceptional, (10 reviews)
"This was a great boutique hotel, staff was helpful, stayed in the cobalto suite which was clean and luxurious, they had pottery which they sell as souvenirs, we didn’t try the restaurant but it looked very nice, would stay here again."
United States
Saahir
The price is Rp4.939.135
Rp5.902.267 total
includes taxes & fees
30 Nov - 1 Dec
Casa Talavera by Tasman
A courtyard with a staircase leading to a second floor, surrounded by potted plants and a large hedge.

3. Casa Seis Siete

Casa Seis Siete
3.0 star property
Roma Norte, 1.3 km from National Medical Center (Siglo XXI)
10.0 out of 10, Exceptional, (67 reviews)
"Perfect location to stay for your time in CDMX. Easily walkable to public transportation as well as things to do and see in Roma Norte and Condessa. The staff go over the top to welcome you and make you feel at home. Breakfast is amazing as well. One of the favorite places I’ve ever stayed"
United States
Jennifer
The price is Rp5.387.254
Rp6.437.769 total
includes taxes & fees
1 Dec - 2 Dec
Casa Seis Siete
A courtyard with outdoor seating, a stone wall, and a variety of plants.

4. Casa Bamboo

Casa Bamboo
2.0 star property
1.2 km from National Medical Center (Siglo XXI)
9.8 out of 10, Exceptional, (18 reviews)
"Close yo my Family, very reasonably priced!"
United States
John
The price is Rp701.556
Rp838.361 total
includes taxes & fees
23 Nov - 24 Nov
Casa Bamboo
A modern kitchen with a wooden island, built-in shelves, and a view of a garden.

5. Lulu Condesa by Capitalia

Lulu Condesa by Capitalia
4.0 star property
Hipódromo, 1.8 km from National Medical Center (Siglo XXI)
10.0 out of 10, Exceptional, (20 reviews)
"Perfect location. Great service. Rooftop jacuzzi with great views"
United States
Anonymous traveller
The price is Rp8.976.814
Rp10.861.945 total
includes taxes & fees
9 Dec - 10 Dec
Lulu Condesa by Capitalia
A narrow alley with brick walls, potted plants, and a tree trunk.

6. Taá Guesthouse

Taá Guesthouse
4.0 star property
Roma Norte, 1.3 km from National Medical Center (Siglo XXI)
9.8 out of 10, Exceptional, (9 reviews)
"I enjoyed my stay and would highly recommend it, particularly if you are looking for something more interesting than chain hotels!"
United States
Jacob
The price is Rp1.469.706
Rp2.663.729 total
includes taxes & fees
1 Dec - 2 Dec
Taá Guesthouse
A modern interior with a wooden floor, a bed, a sofa, and a dining table.

7. La Valise Mexico City, Member of Small Luxury Hotels

La Valise Mexico City, Member of Small Luxury Hotels
5.0 star property
Roma Norte, 1.6 km from National Medical Center (Siglo XXI)
9.8 out of 10, Exceptional, (56 reviews)
"I can’t recommend the hotel enough. The rooms were very clean and the staff was very attentive. They helped us every step of the way. The location was also very central and the breakfast was amazing. The projectors were fun to use."
United States
Brandon
The price is Rp12.158.616
Rp15.252.095 total
includes taxes & fees
15 Nov - 16 Nov
La Valise Mexico City, Member of Small Luxury Hotels
A rooftop terrace with outdoor seating, a pergola, and a city view.

8. ULIV Pulse Roma - Condesa

ULIV Pulse Roma - Condesa
4.5 star property
Roma Sur, 1.7 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (1,064 reviews)
"Great location, shopping, restaurants, parks."
United States
Ricardo
The price is Rp1.873.288
Rp2.238.579 total
includes taxes & fees
13 Dec - 14 Dec
ULIV Pulse Roma - Condesa
A modern hotel room with a wooden ceiling, two beds, a desk, and a view of greenery through large windows.

9. Colima 71 Casa de Arte Hotel

Colima 71 Casa de Arte Hotel
3.0 star property
Roma Norte, 1.4 km from National Medical Center (Siglo XXI)
9.8 out of 10, Exceptional, (54 reviews)
"This was by far the coolest hotel in the best location with the best staff and ambiance"
United States
Bobbi
The price is Rp8.288.018
Rp10.781.228 total
includes taxes & fees
1 Dec - 2 Dec
Colima 71 Casa de Arte Hotel
A hotel room with a balcony, a bed with white linens, and a view of the cityscape.

10. Casa Oliva

Casa Oliva
3.0 star property
Roma Norte, 1.7 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (191 reviews)
"I will definitely go back The staff the apartment so cozy and clean Safe all secured just can’t stop raving about it"
United States
Lisa
The price is Rp2.087.720
Rp2.494.825 total
includes taxes & fees
17 Nov - 18 Nov
Casa Oliva
A dark arched entrance with a decorative metal gate, a street lamp above, and a building number sign.

11. Casa Mannach

Casa Mannach
3.5 star property
Hipódromo, 1.7 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (158 reviews)
"Truly couldn't have asked for a better spot to stay. Every person I spoke with was incredibly helpful and kind; from the cleaning staff to Luis and Pablo who always said hello whenever I would walk in and out. Would absolutely come back to stay again."
United States
Rebekah
The price is Rp2.152.108
Rp2.571.713 total
includes taxes & fees
16 Nov - 17 Nov
Casa Mannach
A modern living room with a sofa, dining table, and chairs, a kitchen area with a refrigerator, and large windows offering a view of greenery.

12. Boga Mexico City by Lumina

Boga Mexico City by Lumina
4.5 star property
Roma Norte, 1.6 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (99 reviews)
"Clean room & air conditioning was such a plus!! The bed was so comfy!!!! I would definitely stay here again"
United States
Dianaris
The price is Rp3.288.303
Rp3.929.522 total
includes taxes & fees
13 Dec - 14 Dec
Boga Mexico City by Lumina
An outdoor cafe area with tables and chairs, surrounded by palm trees and a building with a sign reading "Fritur".

13. Condesa Residence Campeche 276

Condesa Residence Campeche 276
3.0 star property
Hipódromo, 1.8 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (92 reviews)
"Excellent location. Everything was pretty much walkable. Beautiful green sceneries. Priceless!"
United States
Liliana
The price is Rp2.022.944
Rp2.417.418 total
includes taxes & fees
16 Nov - 17 Nov
Condesa Residence Campeche 276
A modern interior with a large window, wooden furniture, and potted plants.

14. Casa Tenue

Casa Tenue
3.5 star property
Roma Norte, 1.6 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (22 reviews)
"The design of Casa Tenue is exceptionally thoughtful and beautiful. Each detail has been carefully conceived to create a visual and functional environment. Both Jorge and Joseph were very attentive hosts. All together a totally unique and wonderful experience."
United States
Donald
The price is Rp8.726.439
Rp10.428.094 total
includes taxes & fees
9 Dec - 10 Dec
Casa Tenue
A modern building with a covered outdoor seating area surrounded by potted plants and trees.

15. Cuadra 134 Residencial Condesa

Cuadra 134 Residencial Condesa
4.5 star property
Roma Norte, 1 km from National Medical Center (Siglo XXI)
9.4 out of 10, Exceptional, (439 reviews)
"It was very safe close to everything and they were very helpful the entire time."
United States
Mariela
The price is Rp2.065.101
Rp2.467.796 total
includes taxes & fees
13 Dec - 14 Dec
Cuadra 134 Residencial Condesa
A modern bedroom with a large bed, a TV mounted on the wall, and a balcony with outdoor furniture.

16. OM686 Urban Lofts Short-Long Stays

OM686 Urban Lofts Short-Long Stays
3.0 star property
1 km from National Medical Center (Siglo XXI)
9.4 out of 10, Exceptional, (278 reviews)
"Excellent location during my time there. Staff were very helpful and accommodating."
United States
Aloefuna
The price is Rp1.032.414
Rp1.233.734 total
includes taxes & fees
30 Nov - 1 Dec
OM686 Urban Lofts Short-Long Stays
A rooftop terrace with a sofa, a small table, and a dining area with chairs.

17. ULIV Roma Norte

ULIV Roma Norte
4.0 star property
Roma Norte, 0.8 km from National Medical Center (Siglo XXI)
9.4 out of 10, Exceptional, (525 reviews)
"Great place. Location is great."
United States
Edgar
The price is Rp1.827.675
Rp2.184.072 total
includes taxes & fees
8 Dec - 9 Dec
ULIV Roma Norte
A modern living room with a grey sofa, two black side tables, and a painting of a bridge.

18. Narvarte Living

Narvarte Living
3.0 star property
1.1 km from National Medical Center (Siglo XXI)
9.4 out of 10, Exceptional, (20 reviews)
"Great space at a great rate. We would definitely stay here again."
United States
Daniel
The price is Rp1.320.500
Rp1.578.000 total
includes taxes & fees
9 Dec - 10 Dec
Narvarte Living
An outdoor dining area with multiple tables and chairs, set against a backdrop of a city skyline at dusk.

19. Hotel Casa Izel Roma Norte

Hotel Casa Izel Roma Norte
4.5 star property
Roma Norte, 1.8 km from National Medical Center (Siglo XXI)
9.4 out of 10, Exceptional, (185 reviews)
"Great location and sophisticated atmosphere yet friendly staff members. Would love to visit again!"
United States
Atsuko
The price is Rp4.269.297
Rp5.101.810 total
includes taxes & fees
15 Nov - 16 Nov
Hotel Casa Izel Roma Norte
A modern office space with a wooden reception desk, a door with a number sign, and a computer monitor on a stand.

20. Hotel Escala Colonia Roma

Hotel Escala Colonia Roma
2.0 star property
Roma Norte, 0.6 km from National Medical Center (Siglo XXI)
9.2 out of 10, Wonderful, (543 reviews)
"Great location"
Canada
Seyedeh Zahra
The price is Rp818.576
Rp978.198 total
includes taxes & fees
13 Dec - 14 Dec
Hotel Escala Colonia Roma
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to National Medical Center (Siglo XXI)

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A room with a wooden floor, a blue chair, a wooden cabinet, and a door leading to a balcony with a metal railing and greenery.
NaNa Vida CDMX
4.0 star property
10.0
Exceptional
475 reviews
View
A building with ornate tiled facades, arched windows, and a balcony with a wrought iron railing.
Casa Talavera by Tasman
2.5 star property
10.0
Exceptional
10 reviews
View
A courtyard with a staircase leading to a second floor, surrounded by potted plants and a large hedge.
Casa Seis Siete
3.0 star property
10.0
Exceptional
67 reviews
View
A courtyard with outdoor seating, a stone wall, and a variety of plants.
Casa Bamboo
2.0 star property
9.8
Exceptional
18 reviews
View
A modern kitchen with a wooden island, built-in shelves, and a view of a garden.
Lulu Condesa by Capitalia
4.0 star property
10.0
Exceptional
20 reviews
View

Top National Medical Center (Siglo XXI) Hotel Reviews

A historic building with multiple balconies, a ground-floor shop, and a well-lit entrance.
Histórico Central Hotel

Histórico Central Hotel

Histórico Central Hotel
Historic Center

10/10 Excellent

Excellent location - 2 mins walk to Zocalo. There is a 24hr cafe and all food and drinks are completely free. The only main point is that they have a very limited vegetarian choice.
United Kingdom
Sonal
Reviewed July 28, 2026
Histórico Central Hotel

Frequently Asked Questions

What's the area like around National Medical Center (Siglo XXI)?

National Medical Center (Siglo XXI) is located in a historic area of Mexico City known for its top museums and popular art scene. If you're looking for a convenient place to stay, take a look at the 712 hotels and other accommodation options you'll find within a mile.

What's the best place to stay close to National Medical Center (Siglo XXI)?

Hotel Benidorm Mexico City is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and free valet parking. It's located just a short 0.4 mi (0.7 km) from National Medical Center (Siglo XXI). Other good choices close by include ULIV Roma Norte and Hotel El Estadio.

How many hotels will I be able to find close to National Medical Center (Siglo XXI)?

Expedia has 712 hotels and other accommodation options within a mile from National Medical Center (Siglo XXI).

If I need to cancel the hotel reservation for my stay near National Medical Center (Siglo XXI), will I receive a refund?

Yes, most room reservations are refundable provided that you cancel before the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best deals near National Medical Center (Siglo XXI).

What can I see and do near National Medical Center (Siglo XXI)?

Chapultepec Castle, Templo Mayor Museum and San Ildefonso College feature a variety of fascinating exhibits to see while you're in town. Palacio de Bellas Artes, Paseo de la Reforma and Cibeles Fountain are some of the local landmarks to explore. You can watch performances at Blackberry Auditorium, Poliforum Siqueiros and Teatro Metropólitan if you're interested in local theatre.

How can I get to National Medical Center (Siglo XXI)?

With so many choices for transport, seeing the area around National Medical Center (Siglo XXI) is a breeze. You can access metro transport at Revolution Station, Metrobús Revolución Station and Buenavista Metro Station. To see more of the larger area, ride aboard one of the trains from Mexico City Buenavista Station.