Otay Mesa West Travel Guide

San Diego

Photo by Leonardo De Leon
Photo by Leonardo De Leon

Popular places to visit

Things to do


Top hotels in Otay Mesa West

Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the pool and the bar in their ...
8/10 Very Good! (1,905 reviews)
"The best part of this place was the fabulous pool. The staff was helpful and pleasant. The room was adequate, but it could use a facelift. Wall paper was warped towards the floor and our sliding door was stuck. Air conditioning worked very well, and the beds were comfortable. I will stay here again. ..."

Reviewed on 23 Jul 2025

Handlery Hotel
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
The price is Rp2.340.777 per night from 27 Jul to 28 Jul
Rp2.340.777
Rp3.181.925 total
27 Jul - 28 Jul
includes taxes & fees
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,782 reviews)
San Diego hotel
"This hotel is in a great location to lots of things to do. I stayed in a room with a bay view and it was beautiful. The rooms have balconies and it was wonderful leaving the balcony door open to let in the ocean breeze. Room is comfortable and clean but my shower did not drain. Definitely recommend ..."

Reviewed on 25 Jul 2025

Wyndham San Diego Bayside
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is Rp3.211.744 per night from 28 Jul to 29 Jul
Rp3.211.744
Rp4.604.041 total
28 Jul - 29 Jul
includes taxes & fees
Stay at this 4-star eco-certified hotel in San Diego. Enjoy free Wi-Fi, 6 restaurants and 3 bars/lounges. Our guests praise the pool and the bar in their reviews. ...
9/10 Wonderful! (2,793 reviews)
"I reserved a corner room and they upgraded to a deluxe room. It had great views and the walk along the bay was enjoyable."

Reviewed on 23 Jul 2025

Manchester Grand Hyatt San Diego
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
The price is Rp2.698.452 per night from 25 Aug to 26 Aug
Rp2.698.452
Rp3.101.736 total
25 Aug - 26 Aug
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina and 2 hot tubs. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (3,582 reviews)
Perfect Staycation Hotel
"This is our 4th time staying at the Dana and we love it! Such beautiful views and even tho a bit pricey, my kids love it has 2 pools with 2 spas and movie nights! The staff are great and it’s very quiet and home feeling . We will be back in a couple of months !"

Reviewed on 22 Jul 2025

The Dana on Mission Bay
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4 out of 5
333 W Harbor Dr, San Diego, CA
The price is Rp3.798.364 per night from 17 Aug to 18 Aug
Rp3.798.364
Rp5.131.348 total
17 Aug - 18 Aug
includes taxes & fees
Stay at this spa hotel in San Diego. Enjoy 2 outdoor pools, a full-service spa and 5 restaurants. Our guests praise the pool and the helpful staff in their reviews. ...
9/10 Wonderful! (1,782 reviews)
"Best place to stay in 💯"

Reviewed on 24 Jul 2025

Marriott Marquis San Diego Marina
The Dextro Hotel, BW Premier Collection

The Dextro Hotel, BW Premier Collection

3 out of 5
1617 1st Avenue, San Diego, CA
The price is Rp1.982.776 per night from 3 Aug to 4 Aug
Rp1.982.776
Rp2.295.063 total
3 Aug - 4 Aug
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the helpful ...
7.6/10 Good! (1,043 reviews)
Pleasantly Surprised
"We were pleasantly surprised the hotel this is much nicer in person than what is shown online. It was modern, updated and very clean. After reading all of these reviews, I was worried about the parking situation, especially since I had a larger vehicle. But it wasn't so bad since I was able to park ..."

Reviewed on 24 Jul 2025

The Dextro Hotel, BW Premier Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Otay Mesa West

Gaslamp Quarter featuring a bar, night scenes and street scenes

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.

Gaslamp Quarter
Default Image

Downtown San Diego

4.5/5(138 area reviews)

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Downtown San Diego
Default Image

Little Italy

Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.

Little Italy
Default Image

North Park

North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.

North Park
Default Image

Mid-City

While you're in Mid-City, take in top sights like Cal Coast Credit Union Open Air Theater or Viejas Arena, and hop on the metro to see more of the city at SDSU Transit Center Station or Alvarado Station.

Mid-City
Default Image

Hillcrest

5/5(1 area review)

Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.

Hillcrest

Otay Mesa West Travel Guide