Visit South Main
Popular places to visit
George R. Brown Convention Center
During your trip, find out what's happening in George R. Brown Convention Center, a top convention centre in Houston. Experience the acclaimed theatre scene and entertainment choices in this vibrant area.
NASA Johnson Space Center
After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event.
Daikin Park
Catch an event at Daikin Park during your trip to Houston. Experience the entertainment choices and great live music in this vibrant area.
Toyota Center
Catch an event at Toyota Center during your trip to Houston. Experience the entertainment choices and lively festivals in this vibrant area.
Rice University
Walk around the campus of Rice University, a top university in Houston. Experience the area's acclaimed theatre scene and fascinating museums.
University of Houston
Walk around the campus of University of Houston, a top university in Houston. Experience the great live music and lively festivals in this vibrant area.
Things to do
Space Center Houston Admission Ticket
Houston's Official City & Mural Tour!
Houston Museum of Natural Sciences: Planetarium Ticket
Houston Museum of Natural Science and Cockrell Butterfly Center
Astroville Best of Houston City Driving Tour with Live Guide
Houston: Houston Botanic Garden Entry Ticket
Top hotels in South Main
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Only the hot water runs in the bath room sink.
Reviewed on 5 Nov 2025
Hotel Zaza Houston Museum District
The staff was outstanding, especially Daisy, the front desk manager and Alexandria. I had a mishap, that was soon forgotten, because of the 1st class customer service I received from these two ladies. The rooms were cozy, comfortable, and extremely clean. When the mishap, happened, I was immediately ...
Reviewed on 30 Oct 2025
Club Quarters Hotel Downtown, Houston
Everything was great!
Reviewed on 31 Oct 2025
Heritage Place Houston Brookhollow
Great staff, quiet, super clean and comfortable
Reviewed on 3 Nov 2025
DoubleTree by Hilton Hotel Houston - Greenway Plaza
Yes
Reviewed on 3 Nov 2025
Magnolia Hotel Houston, A Tribute Portfolio Hotel
Clean rooms and soft bed
Reviewed on 3 Nov 2025
Other neighbourhoods around South Main
Astrodome
While you're in Astrodome, take in top sights like NRG Stadium or NRG Arena, and hop on the metro to see more of the city at Stadium Park/Astrodome Station or Smith Lands Station.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Museum District
Known for its abundant dining options and interesting museums, there's plenty to explore in Museum District. Top attractions like Houston Zoo and Children's Museum of Houston are major draws, and you can catch the metro at M. D. Anderson Station or Museum District Station to see more of the city.
South Central Houston
If you're spending time in South Central Houston, check out sights like Houston Zoo or Continental Club and hop on the metro to see more of the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Houston Center for Photography while you're exploring the area.
River Oaks
Gardens and monuments are just a few things travellers like about River Oaks. A stop by River Oaks Country Club is also recommended if you've got time to explore the area.
