Visit South Main
Popular places to visit
George R. Brown Convention Center
During your trip, find out what's happening in George R. Brown Convention Center, a top convention centre in Houston. Experience the great live music and lively festivals in this vibrant area.
NASA Johnson Space Center
After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event.
Daikin Park
Catch an event at Daikin Park during your trip to Houston. Experience the lively festivals and great live music in this vibrant area.
Toyota Center
Catch an event at Toyota Center during your trip to Houston. Experience the acclaimed art galleries and entertainment choices in this vibrant area.
Space Center Houston
This iconic “mission control” was immortalized for its role in the first moon landing.
Rice University
Enjoy the student vibe when you visit Rice University during your travels in Houston. Experience the area's acclaimed theatre scene and lively festivals.
Things to do
Space Center Houston Admission Ticket
Houston's Official City & Mural Tour!
Houston: Houston Botanic Garden Entry Ticket
Houston: Children's Museum Houston Entry Ticket
Meow Wolf's Radio Tave in Houston
Top hotels in South Main
Blossom Hotel Houston, Curio Collection by Hilton
Excellent hotel !!!
Reviewed on 18 Jan 2026
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Thanks
Reviewed on 18 Jan 2026
Club Quarters Hotel Downtown, Houston
Quick and easy. Only part is finding it with it being on the side valet
Reviewed on 18 Jan 2026
The Royal Sonesta Houston Galleria
Everything was great!!! Clean Room
Reviewed on 18 Jan 2026
La Quinta Inn & Suites by Wyndham Houston Bush IAH South
Everything was perfect. However we did not know they didn’t have a restaurant. The closest one was quite a walk away - exhausting for our elderly friend.
Reviewed on 13 Jan 2026
DoubleTree by Hilton Hotel Houston - Greenway Plaza
Very nice staff
Reviewed on 16 Jan 2026
Other neighbourhoods around South Main
Astrodome
While you're in Astrodome, take in top sights like NRG Stadium or NRG Arena, and hop on the metro to see more of the city at Stadium Park/Astrodome Station or Smith Lands Station.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Museum District
Known for its abundant dining options and interesting museums, there's plenty to explore in Museum District. Top attractions like Children's Museum of Houston and Houston Natural Science Museum are major draws, and you can catch the metro at M. D. Anderson Station or Museum District Station to see more of the city.
South Central Houston
If you're spending time in South Central Houston, check out sights like Children's Museum of Houston or Houston Natural Science Museum and hop on the metro to see more of the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
River Oaks
Gardens and monuments are just a few things travellers like about River Oaks. A stop by River Oaks Country Club is also recommended if you've got time to explore the area.
