Search Hotels in South Main, Houston
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Our top choices for South Main hotels
1. Candlewood Suites Houston Medical Center by IHG
Candlewood Suites Houston Medical Center by IHGSouth Main
7.4 out of 10, Good, (889 reviews)
"This place had"
Marvin
The price is Rp1.340.214
Rp1.568.050 total
includes taxes & fees
27 Aug - 28 Aug
2. Wyndham Houston near NRG Park/Medical Center
Wyndham Houston near NRG Park/Medical CenterSouth Main
7.2 out of 10, Good, (1,376 reviews)
"Room was clean and the staff was very nice."
Juan
The price is Rp1.659.101
Rp1.941.149 total
includes taxes & fees
12 Aug - 13 Aug
3. Quality Inn & Suites NRG Park - Medical Center
Quality Inn & Suites NRG Park - Medical CenterSouth Main
6.6 out of 10, (1,005 reviews)
"convenient to medical center"
Mike
The price is Rp1.124.693
Rp1.315.892 total
includes taxes & fees
24 Aug - 25 Aug
4. Comfort Suites Houston near Medical Center- NRG Stadium
Comfort Suites Houston near Medical Center- NRG StadiumSouth Main
8.8 out of 10, Excellent, (1,000 reviews)
"Friendly staff. Nice comfortable room at a very reasonable rate. Lobby area was very clean. The pool area however left much to be desired; it was small and not clean at all."
ken
The price is Rp1.881.008
Rp2.200.779 total
includes taxes & fees
24 Aug - 25 Aug
5. Wingate Houston near NRG Park/Medical Center
Wingate Houston near NRG Park/Medical CenterSouth Main
6.6 out of 10, (1,001 reviews)
"Good parking"
joseph
The price is Rp1.524.041
Rp1.783.028 total
includes taxes & fees
2 Aug - 3 Aug
6. Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG
Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG1.4 km from South Main
9.4 out of 10, Exceptional, (1,006 reviews)
"My stay was great"
Cheryl
The price is Rp2.137.098
Rp2.515.076 total
includes taxes & fees
4 Aug - 5 Aug
7. Hyatt Place Houston Medical Center
Hyatt Place Houston Medical CenterTexas Medical Center, 3.1 km from South Main
9.2 out of 10, Wonderful, (2,605 reviews)
"Great place to visit"
Jasmine
The price is Rp2.300.097
Rp2.705.376 total
includes taxes & fees
6 Aug - 7 Aug
8. Blossom Hotel Houston, Curio Collection by Hilton
Blossom Hotel Houston, Curio Collection by HiltonTexas Medical Center, 3.5 km from South Main
9.0 out of 10, Wonderful, (3,843 reviews)
"Excellent staff, service and amenities. Everything was great, highly recommend staying here!"
Feroze
The price is Rp2.996.827
Rp3.506.286 total
includes taxes & fees
29 Aug - 30 Aug
9. Hyatt House Houston Medical Center
Hyatt House Houston Medical CenterTexas Medical Center, 3.1 km from South Main
9.2 out of 10, Wonderful, (1,258 reviews)
"Very reliable hotel"
Leland
The price is Rp2.197.677
Rp2.584.911 total
includes taxes & fees
9 Aug - 10 Aug
10. Hotel Ylem
Hotel Ylem2.3 km from South Main
8.4 out of 10, Very good, (1,539 reviews)
"Great staff, good breakfast and room in good condition"
Bruno
The price is Rp1.408.991
Rp1.739.073 total
includes taxes & fees
11 Aug - 12 Aug
11. The Westin Houston Medical Center/Museum District
The Westin Houston Medical Center/Museum DistrictTexas Medical Center, 4.4 km from South Main
9.2 out of 10, Wonderful, (1,160 reviews)
"The bar was great vibes and the morning bartender was the best definitely will visit again soon!"
Brandon
The price is Rp2.601.645
Rp3.238.269 total
includes taxes & fees
1 Aug - 2 Aug
12. Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical CenterTexas Medical Center, 4.4 km from South Main
8.4 out of 10, Very good, (2,065 reviews)
"Great place to stay at super clean and nice area and everything was nearby"
Marvin
The price is Rp2.318.353
Rp2.733.482 total
includes taxes & fees
28 Aug - 29 Aug
13. Drury Inn & Suites Houston Near the Galleria
Drury Inn & Suites Houston Near the GalleriaThe Galleria, 9.4 km from South Main
9.4 out of 10, Exceptional, (1,495 reviews)
"Near everything and the staff was friendly and helpful"
Joaquim
The price is Rp1.629.809
Rp1.906.876 total
includes taxes & fees
9 Aug - 10 Aug
14. Best Western Plus Pearland/Houston Medical Center Hotel
Best Western Plus Pearland/Houston Medical Center HotelSoutheast Houston, 10.2 km from South Main
9.4 out of 10, Exceptional, (375 reviews)
"Clean quiet rooms nice breakfast great staff"
Keitha
The price is Rp1.613.871
Rp1.888.230 total
includes taxes & fees
4 Aug - 5 Aug
15. Hilton Garden Inn Houston Medical Center, TX
Hilton Garden Inn Houston Medical Center, TXTexas Medical Center, 4.7 km from South Main
9.2 out of 10, Wonderful, (1,000 reviews)
"The staff was very accommodating and the place was very clean."
Donald
The price is Rp2.064.292
Rp2.415.221 total
includes taxes & fees
7 Aug - 8 Aug
16. Crowne Plaza Houston Med Ctr-Galleria Area by IHG
Crowne Plaza Houston Med Ctr-Galleria Area by IHGGreenway Plaza-Upper Kirby, 6.5 km from South Main
7.8 out of 10, Good, (1,552 reviews)
"hotel was clean. staff was courteous and professional. offered buffet breakfast for a very reasonable price. location is ideal. will definitely stay again!"
Deborah
The price is Rp1.177.215
Rp1.377.342 total
includes taxes & fees
10 Aug - 11 Aug
17. Best Western Plus Downtown Inn & Suites
Best Western Plus Downtown Inn & Suites10.2 km from South Main
9.2 out of 10, Wonderful, (1,111 reviews)
"Great place to stay, book here all the time when it town."
MARCOS
The price is Rp2.139.090
Rp2.502.735 total
includes taxes & fees
6 Aug - 7 Aug
18. Hyatt Place Houston/Galleria
Hyatt Place Houston/Galleria8.7 km from South Main
8.8 out of 10, Excellent, (1,560 reviews)
"Excellent stay!!!"
Loukisha
The price is Rp2.013.943
Rp2.368.266 total
includes taxes & fees
2 Aug - 3 Aug
19. Homewood Suites by Hilton Houston Memorial
Homewood Suites by Hilton Houston Memorial16.4 km from South Main
9.6 out of 10, Exceptional, (1,005 reviews)
"Excellent property, rooms, staff, breakfast, location, etc......."
Roland
The price is Rp1.589.059
Rp1.859.199 total
includes taxes & fees
23 Aug - 24 Aug
20. DoubleTree by Hilton Hotel Houston - Greenway Plaza
DoubleTree by Hilton Hotel Houston - Greenway PlazaGreenway Plaza-Upper Kirby, 6.6 km from South Main
8.4 out of 10, Very good, (1,772 reviews)
"Excellent place to stay with family"
Fahad
The price is Rp1.649.550
Rp1.929.908 total
includes taxes & fees
29 Aug - 30 Aug
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels in South Main
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
 Comfort Suites Houston near Medical Center- NRG Stadium | 8.8 Excellent 1,000 reviews | View | ||||||
 Wyndham Houston near NRG Park/Medical Center | 7.2 Good 1,376 reviews | View | ||||||
 Candlewood Suites Houston Medical Center by IHG | 7.4 Good 889 reviews | View | ||||||
 Quality Inn & Suites NRG Park - Medical Center | 6.6 1,005 reviews | View | ||||||
 Wingate Houston near NRG Park/Medical Center | 6.6 1,001 reviews | View |
Where to stay in South Main
Find the best South Main areas for the activities you enjoy most.
Downtown Houston
Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.
The Galleria
Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Photo by George Zimzores
Open Photo by George Zimzores
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
Top South Main Hotel Reviews
Magnolia Hotel Houston, A Tribute Portfolio Hotel
8/10 Good
