Search Hotels in Medical Center District, San Antonio

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Medical Center District hotels

Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
Medical Center District
9.0 out of 10, Wonderful, (1,005 reviews)
"Very comfortable, everything was clean, great staff and it’s near all the important hospitals. "
United States
Jesus
The price is Rp1.672.704
Rp1.952.882 total
includes taxes & fees
11 May - 12 May
Fairfield Inn & Suites by Marriott San Antonio Medical Center

San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1,054 reviews)
"Nice central location..clean rooms"
United States
Sonya
The price is Rp1.866.110
Rp2.217.409 total
includes taxes & fees
17 May - 18 May
San Antonio Marriott Northwest Medical Center

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very good, (3,335 reviews)
"We've stayed here several times over the past 10 years and it's a very good hotel for the price. Clean rooms, well kept bathroom, adequate breakfast. It's in a good location close to the medical center. We will keep it as our primary choice in the area "
United States
Thomas
The price is Rp1.393.918
Rp1.647.736 total
includes taxes & fees
28 May - 29 May
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.2 out of 10, Good, (233 reviews)
"Excellent property!! Staff were very kind."
United States
Archie
The price is Rp868.935
Rp1.101.371 total
includes taxes & fees
20 May - 21 May
OYO Inn & Suites Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,006 reviews)
"Great stay. Clean. Perfect location in Medical Center. "
United States
Carlos
The price is Rp1.707.552
Rp2.018.480 total
includes taxes & fees
13 May - 14 May
Courtyard by Marriott Medical Center San Antonio

Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,316 reviews)
"Close to the medical facilities "
United States
Keith
The price is Rp1.567.986
Rp1.853.500 total
includes taxes & fees
14 May - 15 May
Drury Inn & Suites San Antonio Northwest Medical Center

Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.0 out of 10, (529 reviews)
"It was a comfortable stay. No roaches or bed bugs at affordable prices "
United States
FrankR
The price is Rp658.627
Rp778.556 total
includes taxes & fees
7 May - 8 May
Flex Studios

Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.6 out of 10, Good, (291 reviews)
"Excellent price, area is quite, close to Mays Clinic."
United States
Carol
The price is Rp862.488
Rp1.006.955 total
includes taxes & fees
18 May - 19 May
Atria Inn & Suites

Park Inn by Radisson

Park Inn by Radisson
2.0 star property
Medical Center District
7.2 out of 10, Good, (1,004 reviews)
"courteous and accommodating staff. clean room, easy parking and proximity to medical facility. "
United States
Mary Louise
The price is Rp1.155.211
Rp1.348.710 total
includes taxes & fees
1 Jun - 2 Jun
Park Inn by Radisson

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Country Inn & Suites by Radisson, San Antonio Medical Center, TX
3.0 star property
Medical Center District
6.8 out of 10, (1,003 reviews)
"Great place , front desk are helpful and friendly. Safe place to stay ."
United States
Justin
The price is Rp1.021.918
Rp1.193.196 total
includes taxes & fees
11 May - 12 May
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Studio 6 Extended Stay - San Antonio, TX - Medical Center

Studio 6 Extended Stay - San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.8 out of 10, (889 reviews)
"Good location for medical visit."
United States
jose
The price is Rp871.026
Rp1.064.606 total
includes taxes & fees
7 May - 8 May
Studio 6 Extended Stay - San Antonio, TX - Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (287 reviews)
"The facility is clean, accesible and the staff is kind and helpful. Near to the medical center. "
United States
Yolanda
The price is Rp849.420
Rp991.774 total
includes taxes & fees
10 May - 11 May
Studio 6 San Antonio, Tx - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (999 reviews)
"The staff was couteous and the bed waa clean and comfortable. It was a quiet environment with a peaceful night of sleep."
United States
Melinda
The price is Rp827.640
Rp978.358 total
includes taxes & fees
8 May - 9 May
Motel 6 San Antonio, TX - Northwest Medical Center

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
3.5 star property
Far West Side, 11.3 km from Medical Center District
9.0 out of 10, Wonderful, (1,642 reviews)
"Great location, lots of amenities and great staff."
United States
Arie
The price is Rp1.834.747
Rp2.888.448 total
includes taxes & fees
11 May - 12 May
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

La Quinta Inn & Suites by Wyndham San Antonio Northwest

La Quinta Inn & Suites by Wyndham San Antonio Northwest
3.0 star property
Far West Side, 10.4 km from Medical Center District
8.8 out of 10, Excellent, (1,008 reviews)
"My family and I were extremely impressed with the cleanliness of the facility. It had a very good clean smell all throughout the building. The breakfast was excellent and had Texas shaped waffle makers! Huge plus! Our room was immaculate. The beds were comfortable and the temperature was just right. The rooms are spacious and have plenty of storage for your personal items. We will surely stay here again in the future. "
United States
James
The price is Rp1.466.230
Rp1.711.823 total
includes taxes & fees
10 May - 11 May
La Quinta Inn & Suites by Wyndham San Antonio Northwest

Plaza San Antonio Hotel & Spa, Autograph Collection

Plaza San Antonio Hotel & Spa, Autograph Collection
4.0 star property
Downtown San Antonio, 12.9 km from Medical Center District
9.4 out of 10, Exceptional, (797 reviews)
"A+++ staff. Great pool area. Oasis in the city. Accessible room. Only con - No grab bars in shower or lav. Overall very pleased. "
United States
Kathleen
The price is Rp2.117.887
Rp3.042.553 total
includes taxes & fees
31 May - 1 Jun
Plaza San Antonio Hotel & Spa, Autograph Collection

Spacious & Homey 4br/3ba W/amenities Near Downtown

Spacious & Homey 4br/3ba W/amenities Near Downtown
3.0 star property
15.4 km from Medical Center District
9.0 out of 10, Wonderful, (18 reviews)
"The property was well kept. Each room was large and tastefully decorated. The daily essentials like plates,flatware and glasses were ready available. And on top of everything the was easy to contact during the booking. Also getting to our destination which was to Lackland for a graduation was easy because of the nearby highways. Also near to the Alamo and Riverwalk."
United States
Linda
The price is Rp1.505.434
Rp3.893.559 total
includes taxes & fees
11 May - 12 May
Spacious & Homey 4br/3ba W/amenities Near Downtown

Hampton Inn & Suites Schertz

Hampton Inn & Suites Schertz
2.5 star property
31.1 km from Medical Center District
8.8 out of 10, Excellent, (880 reviews)
"Staff was amazing! Busy area plenty of restaurants close by."
United States
Debra
The price is Rp1.371.887
Rp1.577.670 total
includes taxes & fees
20 May - 21 May
Hampton Inn & Suites Schertz

Extended Stay America Premier Suites - San Antonio - Schertz

Extended Stay America Premier Suites - San Antonio - Schertz
2.5 star property
29.4 km from Medical Center District
9.0 out of 10, Wonderful, (279 reviews)
"Great parking, calm area and very friendly staff. Would definitely stay again. "
United States
Denise
The price is Rp1.567.986
Rp1.803.210 total
includes taxes & fees
1 Jun - 2 Jun
Extended Stay America Premier Suites - San Antonio - Schertz

Comfort Inn & Suites Texas Hill Country

Comfort Inn & Suites Texas Hill Country
2.5 star property
33.8 km from Medical Center District
8.8 out of 10, Excellent, (1,001 reviews)
"Conveniently located, short distance to downtown. Could use more parking spots. Access to Hotel from I-10 frontage road is convenient, but the Hotel sign is somewhat hidden when it is time to make a turn."
United States
Marcela
The price is Rp1.653.126
Rp1.868.032 total
includes taxes & fees
17 May - 18 May
Comfort Inn & Suites Texas Hill Country
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Medical Center District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Lobby
Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
9.2
Wonderful
1,316 reviews
View
Lobby
Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
9.0
Wonderful
1,005 reviews
View
Bar (on property)
Courtyard by Marriott Medical Center San Antonio
3.0 star property
8.8
Excellent
1,006 reviews
View
Lobby
San Antonio Marriott Northwest Medical Center
3.5 star property
8.6
Excellent
1,054 reviews
View
Free daily buffet breakfast
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
8.4
Very good
3,335 reviews
View

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Uptown

If you're spending some time in Uptown, San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum are top sights worth seeing.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista while you're in town.

Fort Sam Houston

You'll love the stunning river views in Fort Sam Houston, and you might want to stick around to check out United States Army Medical Department Museum, a top place to visit.

Top Medical Center District Hotel Reviews

Frequently asked questions

What is Medical Center District like?
Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Are you looking for Medical Center District travel tips? Make sure that you visit USAA Corporate Office Headquarters and Cinemark San Antonio 16 while you're in the neighbourhood.
What's a favourite hotel to stay in Medical Center District?
Based on our traveller data, La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW is one of the top choices for your stay in Medical Center District. This hotel offers free breakfast and an outdoor pool. Other good options for your stay in the area include San Antonio Marriott Northwest Medical Center and Courtyard by Marriott Medical Center San Antonio.
How many hotels will I be able to find in Medical Center District?
Expedia has 133 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.
What can I see and do in this San Antonio neighbourhood?
USAA Corporate Office Headquarters, Cinemark San Antonio 16 and The San Antonio Art Institute are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.