Medical Center District Holidays

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Where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District
Downtown - Riverwalk showing a river or creek, a bridge and boating

Downtown San Antonio

4 out of top 10 points of interest in this area
4.5/5(42 area reviews)

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Find hotels in Downtown San Antonio

Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
Fully refundableReserve now, pay when you stay
The price is Rp1.495.037 per night from 17 Feb to 18 Feb
Rp1.495.037
Rp1.767.107 total
17 Feb - 18 Feb
includes taxes & fees
8.4/10 Very Good! (3,193 reviews)
Check in was great! You can check in in-person or via the link that is texted to you! The room was cozy and super clean. It had modern imenities. Continental break was excellent everyday were there!

Reviewed on 10 Feb 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
Fully refundableReserve now, pay when you stay
The price is Rp1.682.927 per night from 20 Feb to 21 Feb
Rp1.682.927
Rp1.999.809 total
20 Feb - 21 Feb
includes taxes & fees
8.6/10 Excellent! (1,007 reviews)
Everything was great! Exactly what you would expect a Marriott to be.

Reviewed on 15 Feb 2026

San Antonio Marriott Northwest Medical Center
Park Inn by Radisson

Park Inn by Radisson

2 out of 5
7500 Louis Pasteur Drive San Antonio TX
Fully refundableReserve now, pay when you stay
The price is Rp1.075.484 per night from 1 Mar to 2 Mar
Rp1.075.484
Rp1.255.628 total
1 Mar - 2 Mar
includes taxes & fees
7.2/10 Good! (1,001 reviews)
Room was clean and I enjoyed it.

Reviewed on 4 Feb 2026

Park Inn by Radisson
See all 4,790 properties in Medical Center District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Medical Centre District holiday package cost?
Starting from just , a holiday package is your passport to low-priced travel. Create your own Medical Centre District adventure by picking from our huge range of airfares, hotels and rental cars.
How do I get a cheap travel package to Medical Centre District?
It's as simple as bundling. Hotels, rental cars and flights — combine whatever you need into a Medical Centre District holiday package and save. Score even better deals when you include extras such as activities or tours to your booking. But that's not the only good part. You have the freedom to customize your holiday your own way. We offer over 550 airlines and 1,000,000 properties throughout the world, so that everyone has a chance to travel and fulfil those holiday dreams.
Where should I stay in Medical Centre District?
Make a reservation just around the corner from Six Flags Fiesta Texas, one of this area's most well-known attractions. It's the ideal spot for serious sightseers.
What are the top hotels in Medical Centre District?
Amazing, Contemporary, Beautiful and Fairfield Inn & Suites by Marriott San Antonio Medical Centre are two of the most well-known hotels in Medical Centre District. Why not take a look at the amenities and rates at each and then make up your mind?
How far in advance should I book my Medical Centre District holiday?
It all depends on the airline, but it's usually possible to look up international fares on Expedia up to 12 months in advance. While it's generally recommended to book ahead of time, lucky customers will sometimes nab a cheaper ticket just weeks before the date of departure.
What does an Expedia Medical Centre District travel package include?
Flights, car rentals and hotels — we connect you to the very best deals. All you'll have to do is figure out your ideal combination. Once you've made your booking, you can add on the fun stuff like activities and sightseeing tours. Our travel packages make it easy to customize an exciting Medical Centre District holiday.
What should I know before booking a Medical Centre District travel package?
You'll save plenty with an Expedia travel package. Combine your airfares, rental cars and hotels and land fantastic discounts. You're not limited to hotels, however. Book with us and select from island resorts, city apartments and just about everything in between!
Can I choose my airline with a Medical Centre District Expedia holiday package?
Yes, you're in charge. We have access to over 550 partner airlines globally, so you can tailor your Medical Centre District trip according to your budget and travel needs.
If I'm not able to travel, can I cancel my Medical Centre District holiday package?
Whether it's your hotel or flight, you can cancel or change it. Booked your Medical Centre District holiday package in the last 24 hours? You may be able to make any changes for free. For bookings made more than 24 hours ago, you may be charged a fee by your airline, hotel or car rental company. For more information, head to our Customer Service Portal. We're here to help you every step of the way.

Things to do

San Antonio Zoo Any Day Ticket including ZooLights

San Antonio Zoo Any Day Ticket including ZooLights

Rp497.704
per adult
96% of travellers recommend
San Antonio Zoo Any Day Ticket including ZooLights
SEA LIFE San Antonio

SEA LIFE San Antonio

Rp418.650
per adult
78% of travellers recommend
SEA LIFE San Antonio
See all activities in San Antonio
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.