Medical Center District Travel Guide

San Antonio

A cityscape with a prominent tower, a large body of water, and a sunset.
A canal with colorful umbrellas and trees along the banks.
A riverside café with colorful umbrellas and tables.
A tranquil waterway flanked by lush greenery and stone pathways.
A canal with a boat, surrounded by lush greenery and a stone bridge.

Stay near popular Medical Center District attractions

Things to do


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is Rp1.573.714 per night from 14 Sept to 15 Sept
Rp1.573.714
Rp1.860.101 total
14 Sept - 15 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

3 out of 5
9806 Interstate Hwy 10 W San Antonio TX
The price is Rp1.594.803 per night from 14 Sept to 15 Sept
Rp1.594.803
Rp1.885.201 total
14 Sept - 15 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,436 reviews)
"We ended up only staying 1 of our 3 prepaid nights because the room was so dirty and dated and we decided to cut our losses and drive back the 3 hours home. The pillows smelled like armpits. One of the elevators was broken. The rooms were very dark, dusty and in desperate need of a refresh to be ..."

Reviewed on 31 Aug 2026

Drury Inn & Suites San Antonio Northwest Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr San Antonio TX
The price is Rp1.736.756 per night from 12 Sept to 13 Sept
Rp1.736.756
Rp2.053.002 total
12 Sept - 13 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,000 reviews)
"Property was in a great location and back off the roadway, so it was quiet. The room was big and clean. Bed was comfortable and ac worked great. Staff was very nice and polite."

Reviewed on 30 Aug 2026

Courtyard by Marriott Medical Center San Antonio
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is Rp1.781.986 per night from 2 Oct to 3 Oct
Rp1.781.986
Rp2.117.646 total
2 Oct - 3 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
San Antonio Marriott Northwest Medical Center
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St San Antonio TX
The price is Rp2.419.762 per night from 7 Sept to 8 Sept
Rp2.419.762
Rp3.366.648 total
7 Sept - 8 Sept
includes taxes & fees
Stay at this luxury hotel in San Antonio. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in ...
9.4/10 Exceptional! (3,042 reviews)
"Amazing stay, great location and very friendly staff"

Reviewed on 2 Sept 2026

Hotel Valencia Riverwalk
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

4 out of 5
105 S Saint Marys Street San Antonio TX
The price is Rp2.268.239 per night from 13 Sept to 14 Sept
Rp2.268.239
Rp2.681.262 total
13 Sept - 14 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (5,207 reviews)
"Beautiful hotel with great staff! We always enjoy the breakfast buffet and the evening 'happy hour' is a big plus! The carpet in hallways - or at least on our floor - very much needs to be replaced. Pool is small for such a large hotel, therefore, is usually crowded. Can't beat the location of hotel ..."

Reviewed on 2 Sept 2026

Drury Plaza Hotel San Antonio Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.

Downtown San Antonio

A scenic riverfront great entertainment and top sights from Alamo to Alamodome – discover Downtown San Antonio, a destination also famous for its historic sites.

Uptown

If you're spending some time in Uptown, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Dub Farris Athletic Complex are top sights worth seeing.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista while you're in town.



Medical Center District Travel Guide