Medical Center District Travel Guide

San Antonio

A cityscape with a prominent tower, a large body of water, and a sunset.
A canal with colorful umbrellas and trees along the banks.
A riverside café with colorful umbrellas and tables.
A tranquil waterway flanked by lush greenery and stone pathways.
A canal with a boat, surrounded by lush greenery and a stone bridge.

Stay near popular Medical Center District attractions

Things to do


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is Rp1.591.385 per night from 27 Jul to 28 Jul
Rp1.591.385
Rp1.880.988 total
27 Jul - 28 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very good! (3,496 reviews)
"Location meet my needs"

Reviewed on 18 Jul 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is Rp1.965.038 per night from 1 Aug to 2 Aug
Rp1.965.038
Rp2.335.038 total
1 Aug - 2 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
San Antonio Marriott Northwest Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr San Antonio TX
The price is Rp1.756.258 per night from 1 Aug to 2 Aug
Rp1.756.258
Rp2.076.056 total
1 Aug - 2 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,007 reviews)
"Would recommend it was very clean and the view was amazing. No breakfast"

Reviewed on 17 Jul 2026

Courtyard by Marriott Medical Center San Antonio
Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

3 out of 5
9806 Interstate Hwy 10 W San Antonio TX
Fully refundableReserve now, pay when you stay
The price is Rp1.654.532 per night from 26 Jul to 27 Jul
Rp1.654.532
Rp1.955.807 total
26 Jul - 27 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
Drury Inn & Suites San Antonio Northwest Medical Center
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

4 out of 5
105 S Saint Marys Street San Antonio TX
The price is Rp2.687.971 per night from 16 Aug to 17 Aug
Rp2.687.971
Rp3.177.393 total
16 Aug - 17 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (4,916 reviews)
"Amazing lobby, great snacks, nice rooftop pool and terraces."

Reviewed on 18 Jul 2026

Drury Plaza Hotel San Antonio Riverwalk
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St San Antonio TX
The price is Rp2.107.330 per night from 5 Aug to 6 Aug
Rp2.107.330
Rp3.003.022 total
5 Aug - 6 Aug
includes taxes & fees
Stay at this luxury hotel in San Antonio. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in ...
9.4/10 Exceptional! (2,908 reviews)
"Very nice hotel and comfortable beds. Wasn’t aware there was no hotel parking, didn’t mind going down the street for $9 as they were charging $65 for valet, that was a bit much."

Reviewed on 17 Jul 2026

Hotel Valencia Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.

Downtown San Antonio

A scenic riverfront great entertainment and top sights from Alamo to Alamodome – discover Downtown San Antonio, a destination also famous for its historic sites.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Uptown

If you're spending some time in Uptown, San Antonio Zoo and Aquarium and San Antonio River are top sights worth seeing.

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.



Medical Center District Travel Guide