Search Hotels in Medical Center District, San Antonio

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Medical Center District hotels

Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
Medical Center District
9.0 out of 10, Wonderful, (1,006 reviews)
"clean room staff was very friendly, breakfast was amazing!!"
United States
Drew
The price is Rp1.509.262
Rp1.762.064 total
includes taxes & fees
22 Mar - 23 Mar
Fairfield Inn & Suites by Marriott San Antonio Medical Center

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very good, (3,235 reviews)
"Nice, clean, quiet, easy, quick check in and check out, nice pool and hot tub"
United States
donald
The price is Rp1.505.870
Rp1.780.074 total
includes taxes & fees
22 Mar - 23 Mar
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,007 reviews)
"Very clean and courteous people every time we book there which is alot "
United States
Mary A
The price is Rp1.427.016
Rp1.686.860 total
includes taxes & fees
29 Mar - 30 Mar
Courtyard by Marriott Medical Center San Antonio

San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1,010 reviews)
"Perfect place to stay comfy and clean delicious food good staff thank you much."
United States
Iris Grisell
The price is Rp1.695.122
Rp2.014.300 total
includes taxes & fees
28 Mar - 29 Mar
San Antonio Marriott Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,282 reviews)
"We had a great stay! Staff was always helpful, room was clean. "
United States
Raymalyn
The price is Rp1.526.050
Rp1.803.929 total
includes taxes & fees
22 Mar - 23 Mar
Drury Inn & Suites San Antonio Northwest Medical Center

Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.6 out of 10, Good, (284 reviews)
"Room was good standings, staff was friendly "
United States
Luis
Atria Inn & Suites

Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (259 reviews)
"This Hotel is well lit and we felt safe. The staff was outstanding during check in and check out! Room was very clean. We had a very comfortable stay. "
United States
Gilbert
The price is Rp795.500
Rp928.620 total
includes taxes & fees
22 Mar - 23 Mar
Studio 6 San Antonio, Tx - Northwest Medical Center

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Country Inn & Suites by Radisson, San Antonio Medical Center, TX
3.0 star property
Medical Center District
6.8 out of 10, (1,009 reviews)
"Great place , front desk are helpful and friendly. Safe place to stay ."
United States
Justin
The price is Rp1.053.091
Rp1.229.484 total
includes taxes & fees
22 Mar - 23 Mar
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Park Inn by Radisson

Park Inn by Radisson
2.0 star property
Medical Center District
7.2 out of 10, Good, (1,000 reviews)
"Room was spotless and bed was great."
United States
Pamela
The price is Rp1.081.751
Rp1.262.944 total
includes taxes & fees
12 Apr - 13 Apr
Park Inn by Radisson

Studio 6 Extended Stay - San Antonio, TX - Medical Center

Studio 6 Extended Stay - San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.8 out of 10, (842 reviews)
"Five star service at budget prices"
United States
fidel
The price is Rp720.545
Rp885.547 total
includes taxes & fees
18 Mar - 19 Mar
Studio 6 Extended Stay - San Antonio, TX - Medical Center

OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.2 out of 10, Good, (229 reviews)
"Staff was courteous and professional and the room is nice."
United States
Thomas
The price is Rp979.027
Rp1.261.994 total
includes taxes & fees
31 Mar - 1 Apr
OYO Inn & Suites Medical Center San Antonio

Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (999 reviews)
"Room was clean, beds comfortable, staff extremely friendly and helpful "
United States
Kathleen
The price is Rp805.335
Rp951.979 total
includes taxes & fees
18 Mar - 19 Mar
Motel 6 San Antonio, TX - Northwest Medical Center

Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.0 out of 10, (513 reviews)
"It was a comfortable stay. No roaches or bed bugs at affordable prices "
United States
FrankR
The price is Rp717.323
Rp847.940 total
includes taxes & fees
22 Mar - 23 Mar
Flex Studios

La Quinta Inn & Suites by Wyndham San Antonio Northwest

La Quinta Inn & Suites by Wyndham San Antonio Northwest
3.0 star property
Far West Side, 10.4 km from Medical Center District
8.8 out of 10, Excellent, (1,004 reviews)
"Nice room and good breakfast"
United States
John
The price is Rp1.427.016
Rp1.666.042 total
includes taxes & fees
22 Mar - 23 Mar
La Quinta Inn & Suites by Wyndham San Antonio Northwest

Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB

Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB
2.5 star property
7.7 km from Medical Center District
8.4 out of 10, Very good, (1,008 reviews)
"Great room and price"
United States
William
The price is Rp1.196.387
Rp1.399.772 total
includes taxes & fees
23 Mar - 24 Mar
Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
3.5 star property
Far West Side, 11.3 km from Medical Center District
9.0 out of 10, Wonderful, (1,514 reviews)
"Great place"
United States
Jonatan
The price is Rp1.497.222
Rp2.470.215 total
includes taxes & fees
13 Apr - 14 Apr
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Courtyard by Marriott San Antonio SeaWorld - Westover Hills

Courtyard by Marriott San Antonio SeaWorld - Westover Hills
3.0 star property
Far West Side, 12.1 km from Medical Center District
8.6 out of 10, Excellent, (1,147 reviews)
"Everything was amazing! We got a free upgrade when we got there. Only complaint is that you have to pay to park. Other than that everything was AMAZING! "
United States
Halen
The price is Rp1.715.302
Rp2.038.326 total
includes taxes & fees
29 Mar - 30 Mar
Courtyard by Marriott San Antonio SeaWorld - Westover Hills

Hilton San Antonio Hill Country

Hilton San Antonio Hill Country
4.0 star property
Far West Side, 11.6 km from Medical Center District
8.6 out of 10, Excellent, (1,064 reviews)
"Everything was great and the water was nice!"
United States
Juan
The price is Rp1.749.726
Rp2.737.836 total
includes taxes & fees
23 Mar - 24 Mar
Hilton San Antonio Hill Country

Comfort Suites San Antonio Near Seaworld

Comfort Suites San Antonio Near Seaworld
2.5 star property
7 km from Medical Center District
7.8 out of 10, Good, (1,005 reviews)
"Friendly quiet respectful amazing warm family indoor pool. "
United States
RICARDO
The price is Rp1.383.773
Rp1.615.555 total
includes taxes & fees
29 Mar - 30 Mar
Comfort Suites San Antonio Near Seaworld

Holiday Inn San Antonio Seaworld by IHG

Holiday Inn San Antonio Seaworld by IHG
3.0 star property
Far West Side, 11.9 km from Medical Center District
8.6 out of 10, Excellent, (1,009 reviews)
"Great hotel. Nice gym and good food "
United States
Tremayne D
The price is Rp1.644.926
Rp1.944.451 total
includes taxes & fees
29 Mar - 30 Mar
Holiday Inn San Antonio Seaworld by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Uptown

If you're spending some time in Uptown, San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum are top sights worth seeing.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista while you're in town.

Fort Sam Houston

You'll love the stunning river views in Fort Sam Houston, and you might want to stick around to check out United States Army Medical Department Museum, a top place to visit.

Top Medical Center District Hotel Reviews

Frequently asked questions

What is Medical Center District like?
Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Are you looking for Medical Center District travel tips? Make sure that you visit USAA Corporate Office Headquarters and Cinemark San Antonio 16 while you're in the neighbourhood.
What's a favourite hotel to stay in Medical Center District?
Based on Expedia customer reviews, Drury Inn & Suites San Antonio Northwest Medical Center is the highest ranked property in Medical Center District. This hotel offers free breakfast and an indoor pool. Other favourite options in the area include Fairfield Inn & Suites by Marriott San Antonio Medical Center and Courtyard by Marriott Medical Center San Antonio.
How many hotels will I be able to find in Medical Center District?
Expedia has 119 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.
What can I see and do in this San Antonio neighbourhood?
USAA Corporate Office Headquarters, Cinemark San Antonio 16 and The San Antonio Art Institute are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.