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Our top choices for Medical Center District hotels

1. San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1,090 reviews)
"The Marriot from check in to check out was top notch. Ricky checked me in and was by far the most pleasant, helpful, and accommodating of any concierge I’ve ever encountered. Great stay!"
United States
Paul
The price is Rp1.806.438
Rp2.146.623 total
includes taxes & fees
25 Jul - 26 Jul
San Antonio Marriott Northwest Medical Center

2. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very good, (3,431 reviews)
"Everything was clean and good great place to stay at for family get together"
United States
Juan
The price is Rp1.585.879
Rp1.874.652 total
includes taxes & fees
5 Jul - 6 Jul
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3. OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.4 out of 10, Good, (239 reviews)
"It was quiet and clean and the staff was very friendly"
United States
Ronnie
The price is Rp1.000.104
Rp1.267.631 total
includes taxes & fees
10 Jul - 11 Jul
OYO Inn & Suites Medical Center San Antonio

4. Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.2 out of 10, (543 reviews)
"Yes I would stay again"
United States
Jasper
The price is Rp723.289
Rp854.993 total
includes taxes & fees
25 Jun - 26 Jun
Flex Studios

5. Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,004 reviews)
"The room was spacious and clean, the staff was friendly and helpful, and our stay was well spent."
United States
Dale
The price is Rp1.589.451
Rp1.878.874 total
includes taxes & fees
11 Jul - 12 Jul
Courtyard by Marriott Medical Center San Antonio

6. Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,356 reviews)
"Price is affordable for us, is very clean and we love bed and pillows, breakfast is good."
United States
Estela
The price is Rp1.607.131
Rp1.899.774 total
includes taxes & fees
6 Jul - 7 Jul
Drury Inn & Suites San Antonio Northwest Medical Center

7. Park Inn by Radisson

Park Inn by Radisson
2.0 star property
Medical Center District
7.2 out of 10, Good, (1,000 reviews)
"This was our 2nd time staying and it was even better than the last. The room was very clean, nicely updated, and super comfy. The morning coffee was a hit as well. We come to SA often so this is going to be our first choice for stays. We had been on a road trip for 6 days and this was our final stop. Literally the best place we stayed."
United States
Elizabeth
The price is Rp1.199.232
Rp1.400.103 total
includes taxes & fees
8 Jul - 9 Jul
Park Inn by Radisson

8. Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
Medical Center District
9.0 out of 10, Wonderful, (1,013 reviews)
"Was a great stay. "
United States
Sunanda
The price is Rp1.544.446
Rp1.803.141 total
includes taxes & fees
19 Jul - 20 Jul
Fairfield Inn & Suites by Marriott San Antonio Medical Center

9. Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (308 reviews)
"We liked that the property was quiet and staff was courteous and helpful. We would have liked more towels in the bathroom."
United States
Alma
The price is Rp837.766
Rp977.959 total
includes taxes & fees
1 Jul - 2 Jul
Studio 6 San Antonio, Tx - Northwest Medical Center

10. Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (1,003 reviews)
"The staff and the fast check in and out."
United States
José
The price is Rp729.362
Rp906.701 total
includes taxes & fees
25 Jun - 26 Jun
Motel 6 San Antonio, TX - Northwest Medical Center

11. Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Country Inn & Suites by Radisson, San Antonio Medical Center, TX
3.0 star property
Medical Center District
7.0 out of 10, Good, (1,000 reviews)
"It was a comfortable stay"
United States
Eric
The price is Rp1.188.596
Rp1.387.685 total
includes taxes & fees
2 Jul - 3 Jul
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

12. Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.4 out of 10, Good, (298 reviews)
"The stay wasn’t HORRIBLE but it definitely wasn’t great. When we got to our room there were old clothes from previous guest in the drawers…on top of that we needed clean towels and they had nothing available. The worst part to say though is that there were some very suspicious people walking around and peeping through my truck window-I’m not sure if they were even guests. I thought the neighborhood was good but it’s actually kinda bad, so don’t expect a relaxing night. Everything else was mid...
United States
Alyssa
Atria Inn & Suites

13. Studio 6 Extended Stay - San Antonio, TX - Medical Center

Studio 6 Extended Stay - San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.8 out of 10, (925 reviews)
"It was an amazing stay "
United States
Cordale
The price is Rp892.771
Rp1.091.054 total
includes taxes & fees
25 Jun - 26 Jun
Studio 6 Extended Stay - San Antonio, TX - Medical Center

14. Spark by Hilton San Antonio Dominion

Spark by Hilton San Antonio Dominion
3.0 star property
19.5 km from Medical Center District
9.0 out of 10, Wonderful, (451 reviews)
"Nice and clean, comfortable beds, even the TV remote worked."
United States
Steven
The price is Rp1.177.087
Rp1.268.311 total
includes taxes & fees
20 Jul - 21 Jul
Spark by Hilton San Antonio Dominion

15. Tru by Hilton San Antonio North

Tru by Hilton San Antonio North
2.5 star property
20 km from Medical Center District
8.8 out of 10, Excellent, (736 reviews)
"Great place to stay in"
United States
Yuelin
The price is Rp1.292.634
Rp1.509.150 total
includes taxes & fees
30 Jun - 1 Jul
Tru by Hilton San Antonio North

16. Plaza San Antonio Hotel & Spa, Autograph Collection

Plaza San Antonio Hotel & Spa, Autograph Collection
4.0 star property
Downtown San Antonio, 12.9 km from Medical Center District
9.4 out of 10, Exceptional, (855 reviews)
"Love staying here!"
United States
Bryanda
The price is Rp2.428.824
Rp3.426.146 total
includes taxes & fees
13 Jul - 14 Jul
Plaza San Antonio Hotel & Spa, Autograph Collection

17. Drury Inn & Suites Near La Cantera Parkway

Drury Inn & Suites Near La Cantera Parkway
3.0 star property
La Cantera District, 9.5 km from Medical Center District
9.4 out of 10, Exceptional, (1,727 reviews)
"Everything was excellent well be staying again there"
United States
Juana
The price is Rp1.678.567
Rp1.984.218 total
includes taxes & fees
1 Jul - 2 Jul
Drury Inn & Suites Near La Cantera Parkway

18. Extended Stay America Premier Suites - San Antonio - Schertz

Extended Stay America Premier Suites - San Antonio - Schertz
2.5 star property
29.4 km from Medical Center District
9.0 out of 10, Wonderful, (327 reviews)
"The place was awesome and will definitely stay again"
United States
Joshua
The price is Rp1.607.131
Rp1.848.228 total
includes taxes & fees
25 Jun - 26 Jun
Extended Stay America Premier Suites - San Antonio - Schertz

19. La Quinta Inn & Suites by Wyndham San Antonio Northwest

La Quinta Inn & Suites by Wyndham San Antonio Northwest
3.0 star property
Far West Side, 10.4 km from Medical Center District
8.8 out of 10, Excellent, (1,001 reviews)
"Very clean room, front staff were very helpful and breakfast was good."
United States
Catherine
The price is Rp1.502.835
Rp1.754.560 total
includes taxes & fees
28 Jun - 29 Jun
La Quinta Inn & Suites by Wyndham San Antonio Northwest

20. Best Western Garden Inn

Best Western Garden Inn
2.5 star property
Uptown, 21.2 km from Medical Center District
8.2 out of 10, Very good, (1,000 reviews)
"Very clean, really enjoyed our stay in this place"
United States
Frederick Magtibay
The price is Rp1.214.233
Rp1.417.647 total
includes taxes & fees
28 Jun - 29 Jun
Best Western Garden Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Medical Center District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Lobby
Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
9.2
Wonderful
1,356 reviews
View
Lobby lounge
Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
9.0
Wonderful
1,013 reviews
View
Bar (on property)
Courtyard by Marriott Medical Center San Antonio
3.0 star property
8.8
Excellent
1,004 reviews
View
Lobby
San Antonio Marriott Northwest Medical Center
3.5 star property
8.6
Excellent
1,090 reviews
View
Free daily buffet breakfast
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
8.4
Very good
3,431 reviews
View

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Uptown

If you're spending some time in Uptown, San Antonio Zoo and Aquarium and San Antonio River are top sights worth seeing.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Stone Creek Village and Stone Ridge Market while you're in town.

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

Top Medical Center District Hotel Reviews

Frequently asked questions

What is Medical Center District like?
Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Are you looking for Medical Center District travel tips? Make sure that you visit USAA Corporate Office Headquarters and Cinemark San Antonio 16 while you're in the neighbourhood.
What's a favourite hotel to stay in Medical Center District?
Based on our traveller data, La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW is one of the top choices for your stay in Medical Center District. This hotel offers free breakfast and an outdoor pool. Other good options for your stay in the area include San Antonio Marriott Northwest Medical Center and Drury Inn & Suites San Antonio Northwest Medical Center.
How many hotels will I be able to find in Medical Center District?
Expedia has 134 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.
What can I see and do in this San Antonio neighbourhood?
USAA Corporate Office Headquarters, Cinemark San Antonio 16 and The San Antonio Art Institute are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.