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13 Dec - 14 Dec
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14 Dec - 15 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for Medical Center District hotels

Premium bedding, desk, laptop workspace, free cots/infant beds
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
2.5 star property
Medical Center District
9.0 out of 10, Wonderful, (1003)
"Staff was super nice! "
United States
Fredric
The price is Rp1.381.618
Rp1.613.039 total
includes taxes & fees
22 Dec - 23 Dec
Fairfield Inn & Suites by Marriott San Antonio Medical Center
Food and drink
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very good, (3114)
"quite place with good breakfast"
United States
Juan
The price is Rp1.478.165
Rp1.747.164 total
includes taxes & fees
15 Dec - 16 Dec
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Bar (on property)
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1002)
"Room was clean, staff was very friendly!!"
United States
Ray
The price is Rp1.481.494
Rp1.751.259 total
includes taxes & fees
20 Dec - 21 Dec
Courtyard by Marriott Medical Center San Antonio
Lobby
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1005)
"Clean rooms Staff very nice "
United States
Yolanda
The price is Rp1.481.494
Rp1.760.582 total
includes taxes & fees
18 Dec - 19 Dec
San Antonio Marriott Northwest Medical Center
Lobby
Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1289)
"Great place to stay and visit "
United States
Harry
The price is Rp1.497.974
Rp1.770.635 total
includes taxes & fees
17 Dec - 18 Dec
Drury Inn & Suites San Antonio Northwest Medical Center
Lobby
SpringHill Suites by Marriott San Antonio Medical Center/NW

SpringHill Suites by Marriott San Antonio Medical Center/NW

SpringHill Suites by Marriott San Antonio Medical Center/NW
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1000)
"good staff. good stay"
United States
Divya
The price is Rp1.681.246
Rp1.987.385 total
includes taxes & fees
15 Dec - 16 Dec
SpringHill Suites by Marriott San Antonio Medical Center/NW
Front of property
Atria Inn & Suites

Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.6 out of 10, Good, (274)
"Check-in was smooth, and the room was clean. It needs some repairs and the blanket was as thin as the sheet, but no complaints otherwise."
United States
Rachel
Atria Inn & Suites
Desk, laptop workspace, blackout curtains, free WiFi
Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.2 out of 10, Good, (215)
"Clean, and accommodating room was very a very good Choice!!"
United States
Jessica
The price is Rp882.072
Rp1.029.888 total
includes taxes & fees
15 Dec - 16 Dec
Studio 6 San Antonio, Tx - Northwest Medical Center
Breakfast area
Park Inn by Radisson

Park Inn by Radisson

Park Inn by Radisson
2.0 star property
Medical Center District
7.2 out of 10, Good, (1005)
"Staff were amazing, and everything else was great too. "
United States
Maximilian
The price is Rp1.047.033
Rp1.222.410 total
includes taxes & fees
27 Dec - 28 Dec
Park Inn by Radisson
Desk, laptop workspace, free WiFi, bed sheets
Studio 6 San Antonio, TX - Medical Center

Studio 6 San Antonio, TX - Medical Center

Studio 6 San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.6 out of 10, (787)
"Staff and amenities "
United States
Keyshia
The price is Rp857.902
Rp1.047.409 total
includes taxes & fees
15 Dec - 16 Dec
Studio 6 San Antonio, TX - Medical Center
Basic Room, 1 King Bed, Non Smoking | Desk, iron/ironing board, free WiFi, bed sheets
Flex Studios

Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.0 out of 10, (497)
"heb is nearby. "
United States
Sayeed
The price is Rp689.144
Rp814.629 total
includes taxes & fees
15 Dec - 16 Dec
Flex Studios
Lobby
Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB

Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB

Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB
2.5 star property
7.7 km from Medical Center District
8.4 out of 10, Very good, (992)
"Clean room and friendly staff"
United States
Vanessa
The price is Rp1.047.033
Rp1.222.411 total
includes taxes & fees
21 Dec - 22 Dec
Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB
Indoor pool, outdoor pool
Courtyard by Marriott San Antonio SeaWorld - Westover Hills

Courtyard by Marriott San Antonio SeaWorld - Westover Hills

Courtyard by Marriott San Antonio SeaWorld - Westover Hills
3.0 star property
Far West Side, 12.1 km from Medical Center District
8.6 out of 10, Excellent, (1090)
"It was clean and quiet and the staff was as always amazing"
United States
Chastity
The price is Rp1.542.252
Rp1.832.735 total
includes taxes & fees
22 Dec - 23 Dec
Courtyard by Marriott San Antonio SeaWorld - Westover Hills
Exterior
Hilton San Antonio Hill Country

Hilton San Antonio Hill Country

Hilton San Antonio Hill Country
4.0 star property
Far West Side, 11.6 km from Medical Center District
8.4 out of 10, Very good, (1044)
"Great location for Sea World. Always clean and friendly staff."
United States
Stephen
The price is Rp1.624.317
Rp2.482.057 total
includes taxes & fees
21 Dec - 22 Dec
Hilton San Antonio Hill Country
Terrace/patio
Home2 Suites by Hilton San Antonio Lackland/Sea World, TX

Home2 Suites by Hilton San Antonio Lackland/Sea World, TX

Home2 Suites by Hilton San Antonio Lackland/Sea World, TX
3.0 star property
Far West Side, 11.1 km from Medical Center District
8.8 out of 10, Excellent, (752)
"Clean room and good breakfast! Also service staff was great!"
United States
Darrel
The price is Rp1.518.115
Rp1.853.734 total
includes taxes & fees
21 Dec - 22 Dec
Home2 Suites by Hilton San Antonio Lackland/Sea World, TX
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.
Downtown - Riverwalk showing a river or creek, a bridge and boating

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Uptown

If you're spending some time in Uptown, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista while you're in town.

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.

Top Medical Center District Hotel Reviews

San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

10/10 Excellent
"Great room"
James 2-night trip
Posted 3 days ago
San Antonio Marriott Northwest Medical Center
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

10/10 Excellent
"Beautiful property "
Lynora 2-night trip
Posted 3 days ago
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

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Frequently asked questions

What is Medical Center District like?
Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Are you looking for Medical Center District travel tips? Make sure that you visit USAA Corporate Office Headquarters and The San Antonio Art Institute while you're in the neighbourhood.
What's a favourite hotel to stay in Medical Center District?
Based on Expedia customer reviews, Drury Inn & Suites San Antonio Northwest Medical Center is the highest ranked property in Medical Center District. This hotel offers free breakfast and an indoor pool. Other favourite options in the area include SpringHill Suites by Marriott San Antonio Medical Center/NW and Fairfield Inn & Suites by Marriott San Antonio Medical Center.
How many hotels will I be able to find in Medical Center District?
Expedia has 123 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.
What can I see and do in this San Antonio neighbourhood?
USAA Corporate Office Headquarters, The San Antonio Art Institute and Cinemark San Antonio 16 are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.