Otay Mesa West Travel Guide

San Diego

Photo by Leonardo De Leon
Photo by Leonardo De Leon

Popular places to visit

Things to do


Top hotels in Otay Mesa West

Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
The price is Rp2.075.904 per night from 17 Aug to 18 Aug
Rp2.075.904
Rp2.386.148 total
17 Aug - 18 Aug
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the pool and the bar in their ...
8/10 Very Good! (1,891 reviews)
Birthday Celebration
"Check in was easy, Hotel is older but fairly well maintained, The Staff was friendly and helpful, at the front desk during check in one of the staff team (WHO WAS NOT HELPING US AT ALL) went into a back office and came out a few minutes later with a ballon saying "where is that little guy" That simple ..."

Reviewed on 21 Jul 2025

Handlery Hotel
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
The price is Rp2.344.368 per night from 27 Jul to 28 Jul
Rp2.344.368
Rp3.186.806 total
27 Jul - 28 Jul
includes taxes & fees
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,760 reviews)
"Nice, but lots of fees and expensive parking"

Reviewed on 22 Jul 2025

Wyndham San Diego Bayside
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
The price is Rp3.216.672 per night from 28 Jul to 29 Jul
Rp3.216.672
Rp4.611.106 total
28 Jul - 29 Jul
includes taxes & fees
Stay at this 4-star eco-certified hotel in San Diego. Enjoy free Wi-Fi, 6 restaurants and 3 bars/lounges. Our guests praise the pool and the bar in their reviews. ...
9/10 Wonderful! (2,791 reviews)
"Enjoyed my stay at this place. Friendly and courteous staff"

Reviewed on 21 Jul 2025

Manchester Grand Hyatt San Diego
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
The price is Rp2.922.912 per night from 10 Aug to 11 Aug
Rp2.922.912
Rp3.359.798 total
10 Aug - 11 Aug
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina and 2 hot tubs. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (3,582 reviews)
Perfect Staycation Hotel
"This is our 4th time staying at the Dana and we love it! Such beautiful views and even tho a bit pricey, my kids love it has 2 pools with 2 spas and movie nights! The staff are great and it’s very quiet and home feeling . We will be back in a couple of months !"

Reviewed on 22 Jul 2025

The Dana on Mission Bay
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4 out of 5
333 W Harbor Dr, San Diego, CA
The price is Rp3.804.192 per night from 28 Jul to 29 Jul
Rp3.804.192
Rp5.139.221 total
28 Jul - 29 Jul
includes taxes & fees
Stay at this spa hotel in San Diego. Enjoy 2 outdoor pools, a full-service spa and 5 restaurants. Our guests praise the pool and the helpful staff in their reviews. ...
9/10 Wonderful! (1,773 reviews)
"I had a great experience at this hotel! Everything was spotlessly clean, and the service was excellent!friendly, helpful staff made me feel welcome from the moment I arrived. The location is also a big plus—within easy walking distance to lots of entertainment, restaurants, and attractions. I would ..."

Reviewed on 22 Jul 2025

Marriott Marquis San Diego Marina
The Dextro Hotel, BW Premier Collection

The Dextro Hotel, BW Premier Collection

3 out of 5
1617 1st Avenue, San Diego, CA
The price is Rp1.985.818 per night from 29 Jul to 30 Jul
Rp1.985.818
Rp2.298.584 total
29 Jul - 30 Jul
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the helpful ...
7.6/10 Good! (1,028 reviews)
"It was good, clean room and nice view I think just need more handicap closer parking"

Reviewed on 21 Jul 2025

The Dextro Hotel, BW Premier Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Otay Mesa West

Gaslamp Quarter featuring a bar, night scenes and street scenes

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.

Gaslamp Quarter
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Downtown San Diego

4.5/5(138 area reviews)

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Downtown San Diego
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Little Italy

Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.

Little Italy
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North Park

North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.

North Park
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Mid-City

While you're in Mid-City, take in top sights like Cal Coast Credit Union Open Air Theater or Viejas Arena, and hop on the metro to see more of the city at SDSU Transit Center Station or Alvarado Station.

Mid-City
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Hillcrest

5/5(1 area review)

Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.

Hillcrest

Otay Mesa West Travel Guide