Downtown South San Francisco Travel Guide

San Francisco

Aerial View of a Local High School and an Athletic Field in a Neighborhood in South San Francisco, California, USA
Aerial view of the South San Francisco area
Aerial view of downtown San Francisco and Financial District sky scrapers flying over South San Francisco The Industrial City inscription on San Bruno mountain circa 2015

Popular places to visit

Things to do


Top hotels in Downtown South San Francisco

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3 out of 5
20 Airport Blvd South San Francisco CA
The price is Rp2.016.625 per night from 24 Apr to 25 Apr
Rp2.016.625
Rp2.361.076 total
24 Apr - 25 Apr
includes taxes & fees
Stay at this business-friendly hotel in South San Francisco. Enjoy free breakfast, free Wi-Fi and a free airport shuttle. Our guests praise the breakfast and ...
8.2/10 Very Good! (1,981 reviews)
It felt safe . Wish breakfast included yogurt and fruit.

Reviewed on 10 Apr 2026

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
The price is Rp2.253.452 per night from 12 Apr to 13 Apr
Rp2.253.452
Rp2.652.317 total
12 Apr - 13 Apr
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the pool and the ...
9/10 Wonderful! (5,537 reviews)
Every thing was great

Reviewed on 10 Apr 2026

Holiday Inn Golden Gateway by IHG
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
The price is Rp2.614.004 per night from 6 May to 7 May
Rp2.614.004
Rp3.076.668 total
6 May - 7 May
includes taxes & fees
Stay at this family-friendly hotel in San Francisco. Enjoy free Wi-Fi, a fitness centre and valet parking (surcharge). Our guests praise the pool and the helpful ...
8.8/10 Excellent! (2,992 reviews)
Pool side not used. Parking expensive but secure

Reviewed on 10 Apr 2026

Handlery Union Square Hotel
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
The price is Rp2.377.627 per night from 27 Apr to 28 Apr
Rp2.377.627
Rp3.503.070 total
27 Apr - 28 Apr
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the ...
9/10 Wonderful! (7,383 reviews)
The place looks way nicer online than in person. The rooms were outdated especially for how much they are. They are close to Pier 39 and attractions which was a plus

Reviewed on 10 Apr 2026

Hotel Riu Plaza Fisherman's Wharf
YOTEL San Francisco

YOTEL San Francisco

3 out of 5
1095 Market St San Francisco CA
The price is Rp1.308.456 per night from 12 Apr to 13 Apr
Rp1.308.456
Rp1.841.874 total
12 Apr - 13 Apr
includes taxes & fees
Stay at this hotel in San Francisco. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the helpful staff and the clean rooms in their ...
8.2/10 Very Good! (1,007 reviews)
Yes gym was great.

Reviewed on 10 Apr 2026

YOTEL San Francisco
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St San Francisco CA
The price is Rp2.029.903 per night from 12 Apr to 13 Apr
Rp2.029.903
Rp2.389.087 total
12 Apr - 13 Apr
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the ...
9/10 Wonderful! (3,043 reviews)
Just a quick overnight stay. Room was simple and clean. Staff were friendly. Great location.

Reviewed on 10 Apr 2026

Club Quarters Hotel in San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Downtown South San Francisco

Aerial View Of Urban Neighborhood

Noe Valley

Appreciated for its churches and architecture, you might consider exploring Noe Valley. Check out the variety of things to see and do like 22nd St Hill, and jump on the metro at Church St & Clipper St Stop or Church St & 24th St Stop to get around the city.

Noe Valley
Mission District

Mission District

3.5/5(11 area reviews)

You might enjoy the bars while in Mission District. SOMA Pilipinas is a notable sight, and you can get around town at 16th Street Mission Station or 24th Street Mission Station to see more of the city.

Mission District
Sunset District

Sunset District

3.5/5(6 area reviews)

Consider exploring the beaches in Sunset District. If sightseeing is on the list, Ocean Beach is a top attraction. Hop on the metro at Judah Street & Sunset Boulevard Station or Judah St & 34th Ave Stop to see more of the area.

Sunset District
Outer Sunset

Outer Sunset

When in Outer Sunset and the surrounding area, you'll want to check out sights like Ocean Beach or San Francisco Botanical Garden and hop on the metro to see more of the city at Judah St & 34th Ave Stop or Judah Street & Sunset Boulevard Station.

Outer Sunset
South of Market

South of Market

3.5/5(115 area reviews)

Gourmet restaurants great entertainment and top sights from Oracle Park to San Francisco Bay – discover South of Market, a destination also famous for its shopping.

South of Market
Golden Gate

Golden Gate

If you're spending time in Golden Gate, check out sights like San Francisco Botanical Garden or Japanese Tea Garden and hop on the metro to see more of the city at Irving St & 9th Ave Stop or Irving St & 8th Ave Stop.

Golden Gate


Downtown South San Francisco Travel Guide