Downtown South San Francisco Travel Guide

San Francisco

Aerial View of a Local High School and an Athletic Field in a Neighborhood in South San Francisco, California, USA
Aerial view of the South San Francisco area
Aerial view of downtown San Francisco and Financial District sky scrapers flying over South San Francisco The Industrial City inscription on San Bruno mountain circa 2015

Popular places to visit

Things to do


Top hotels in Downtown South San Francisco

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3 out of 5
20 Airport Blvd South San Francisco CA
The price is Rp1.922.354 per night from 15 Apr to 16 Apr
Rp1.922.354
Rp2.252.684 total
15 Apr - 16 Apr
includes taxes & fees
Stay at this business-friendly hotel in South San Francisco. Enjoy free breakfast, free Wi-Fi and a free airport shuttle. Our guests praise the breakfast and ...
8.2/10 Very Good! (1,971 reviews)
Staff at breakfast was friendly but front desk did not know where laundry room in the hotel was, they said it was in one of the floors when we called and we had to stop by all of them to find it. Room smelled weird and there was barely no water coming out of the bathroom sink. AC did not work the ...

Reviewed on 8 Apr 2026

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
The price is Rp2.241.331 per night from 12 Apr to 13 Apr
Rp2.241.331
Rp2.638.051 total
12 Apr - 13 Apr
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the pool and the ...
9/10 Wonderful! (5,526 reviews)
Staff are veey friendly and helpful Thank you

Reviewed on 9 Apr 2026

Holiday Inn Golden Gateway by IHG
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
The price is Rp2.599.944 per night from 11 Apr to 12 Apr
Rp2.599.944
Rp3.060.119 total
11 Apr - 12 Apr
includes taxes & fees
Stay at this family-friendly hotel in San Francisco. Enjoy free Wi-Fi, a fitness centre and valet parking (surcharge). Our guests praise the pool and the helpful ...
8.8/10 Excellent! (2,978 reviews)
Great stay! Clean and comfortable. Valley service was excellent!

Reviewed on 9 Apr 2026

Handlery Union Square Hotel
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
The price is Rp2.364.838 per night from 12 Apr to 13 Apr
Rp2.364.838
Rp3.484.228 total
12 Apr - 13 Apr
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the ...
9/10 Wonderful! (7,375 reviews)
The room was clean, and the breakfast was great. It's better to go for breakfast around 7:30, because after 8:30 there will be a line to get a table.

Reviewed on 9 Apr 2026

Hotel Riu Plaza Fisherman's Wharf
YOTEL San Francisco

YOTEL San Francisco

3 out of 5
1095 Market St San Francisco CA
The price is Rp1.373.719 per night from 12 Apr to 13 Apr
Rp1.373.719
Rp1.917.061 total
12 Apr - 13 Apr
includes taxes & fees
Stay at this hotel in San Francisco. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the helpful staff and the clean rooms in their ...
8.2/10 Very Good! (1,005 reviews)
Everything was great.

Reviewed on 8 Apr 2026

YOTEL San Francisco
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St San Francisco CA
The price is Rp2.018.984 per night from 12 Apr to 13 Apr
Rp2.018.984
Rp2.376.243 total
12 Apr - 13 Apr
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the ...
9/10 Wonderful! (3,032 reviews)
Clean room. Great location and very helpful staff. Would stay here again.

Reviewed on 8 Apr 2026

Club Quarters Hotel in San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Downtown South San Francisco

Aerial View Of Urban Neighborhood

Noe Valley

Appreciated for its churches and architecture, you might consider exploring Noe Valley. Check out the variety of things to see and do like 22nd St Hill, and jump on the metro at Church St & Clipper St Stop or Church St & 24th St Stop to get around the city.

Noe Valley
Mission District

Mission District

3.5/5(11 area reviews)

You might enjoy the bars while in Mission District. SOMA Pilipinas is a notable sight, and you can get around town at 16th Street Mission Station or 24th Street Mission Station to see more of the city.

Mission District
Sunset District

Sunset District

3.5/5(6 area reviews)

Consider exploring the beaches in Sunset District. If sightseeing is on the list, Ocean Beach is a top attraction. Hop on the metro at Judah Street & Sunset Boulevard Station or Judah St & 34th Ave Stop to see more of the area.

Sunset District
Outer Sunset

Outer Sunset

When in Outer Sunset and the surrounding area, you'll want to check out sights like Ocean Beach or San Francisco Botanical Garden and hop on the metro to see more of the city at Judah St & 34th Ave Stop or Judah Street & Sunset Boulevard Station.

Outer Sunset
South of Market

South of Market

3.5/5(115 area reviews)

Gourmet restaurants great entertainment and top sights from Oracle Park to San Francisco Bay – discover South of Market, a destination also famous for its shopping.

South of Market
Golden Gate

Golden Gate

If you're spending time in Golden Gate, check out sights like San Francisco Botanical Garden or Japanese Tea Garden and hop on the metro to see more of the city at Irving St & 9th Ave Stop or Irving St & 8th Ave Stop.

Golden Gate


Downtown South San Francisco Travel Guide