Downtown South San Francisco Travel Guide

San Francisco

Aerial View of a Local High School and an Athletic Field in a Neighborhood in South San Francisco, California, USA
Aerial view of the South San Francisco area
Aerial view of downtown San Francisco and Financial District sky scrapers flying over South San Francisco The Industrial City inscription on San Bruno mountain circa 2015

Popular places to visit

Things to do


Top hotels in Downtown South San Francisco

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3 out of 5
20 Airport Blvd South San Francisco CA
The price is Rp2.071.921 per night from 31 May to 1 Jun
Rp2.071.921
Rp2.426.521 total
31 May - 1 Jun
includes taxes & fees
Stay at this business-friendly hotel in South San Francisco. Enjoy free breakfast, free Wi-Fi and a free airport shuttle. Our guests praise the breakfast and ...
8.2/10 Very Good! (1,980 reviews)
"Overall good"

Reviewed on 29 May 2026

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is Rp3.123.335 per night from 10 Jun to 11 Jun
Rp3.123.335
Rp4.411.264 total
10 Jun - 11 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the ...
9/10 Wonderful! (7,480 reviews)
"Breakfast was excellent"

Reviewed on 29 May 2026

Hotel Riu Plaza Fisherman's Wharf
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
The price is Rp2.693.318 per night from 5 Jun to 6 Jun
Rp2.693.318
Rp3.169.901 total
5 Jun - 6 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
8.8/10 Excellent! (2,827 reviews)
"No snacks or water/soda in floor venting machines. No microwave."

Reviewed on 29 May 2026

Hilton San Francisco Financial District
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
The price is Rp2.962.436 per night from 28 Jun to 29 Jun
Rp2.962.436
Rp3.486.640 total
28 Jun - 29 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the pool and the ...
9/10 Wonderful! (5,815 reviews)
"Clean rooms, quiet, friendly staff."

Reviewed on 29 May 2026

Holiday Inn Golden Gateway by IHG
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
The price is Rp2.866.960 per night from 5 Jun to 6 Jun
Rp2.866.960
Rp3.374.269 total
5 Jun - 6 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy 2 bars/lounges, breakfast (surcharge) and a 24-hour health club. Our guests praise the helpful staff ...
8.6/10 Excellent! (1,327 reviews)
"Very clean, friendly environment"

Reviewed on 29 May 2026

Hilton San Francisco Union Square
Parc 55 San Francisco - A Hilton Hotel

Parc 55 San Francisco - A Hilton Hotel

4 out of 5
55 Cyril Magnin St San Francisco CA
The price is Rp3.170.342 per night from 19 Jun to 20 Jun
Rp3.170.342
Rp3.731.420 total
19 Jun - 20 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy 2 restaurants, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the helpful ...
8.6/10 Excellent! (1,492 reviews)
"Beautiful and clean hotel. The staff was fast and friendly. The beds were comfortable and the bathrooms very clean. I would definitely stay again."

Reviewed on 29 May 2026

Parc 55 San Francisco - A Hilton Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Downtown South San Francisco

Aerial View Of Urban Neighborhood

Noe Valley

Appreciated for its churches and architecture, you might consider exploring Noe Valley. Check out the variety of things to see and do like 22nd St Hill, and jump on the metro at Church St & Clipper St Stop or Church St & 24th St Stop to get around the city.

Noe Valley
Mission District

Mission District

3.5/5(11 area reviews)

You might enjoy the bars while in Mission District. SOMA Pilipinas is a notable sight, and you can get around town at 16th Street Mission Station or 24th Street Mission Station to see more of the city.

Mission District
Potrero Hill

Potrero Hill

The live music and architecture are just a few things visitors like about Potrero Hill. San Francisco Bay and Museum of Craft & Design are worthwhile spots to check out, and you can hop on the metro at 20th Street Station or 23rd Street Station to get around the larger area.

Potrero Hill
Sunset District

Sunset District

3.5/5(6 area reviews)

Consider exploring the beaches in Sunset District. If sightseeing is on the list, Ocean Beach is a top attraction. Hop on the metro at Judah Street & Sunset Boulevard Station or Judah St & 34th Ave Stop to see more of the area.

Sunset District
South of Market

South of Market

3.5/5(115 area reviews)

Gourmet restaurants great entertainment and top sights from Oracle Park to San Francisco Bay – discover South of Market, a destination also famous for its shopping.

South of Market
Ariel view of the California Academy of Sciences in San Francisco, California.

Golden Gate

If you're spending time in Golden Gate, check out sights like San Francisco Botanical Garden or Japanese Tea Garden and hop on the metro to see more of the city at Irving St & 9th Ave Stop or Irving St & 8th Ave Stop.

Golden Gate


Downtown South San Francisco Travel Guide