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Our top choices for San Francisco hotels with a spa

Spa

1. Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Immerse in tranquility at this Art Deco resort with two treatment rooms for couples and a Turkish bath, where expert spa therapists await.
The price is Rp3.114.072
Rp3.425.479 total
includes taxes & fees
3 Sept - 4 Sept
Sheraton Grand Panama
Terrace/patio

2. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,227 reviews)
  • cleanliness
    Unwind with hot stone massages and facials at this hotel spa with pool views and plush treatment rooms.
The price is Rp1.918.644
Rp2.110.508 total
includes taxes & fees
2 Sept - 3 Sept
Plaza Paitilla Inn Hotel
Spa

3. Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,722 reviews)
  • cleanliness
    Revive in Panama's premier hotel spa with Turkish hammam, hydrotherapy, and multiple treatment rooms for total rejuvenation.
The price is Rp2.016.980
Rp2.218.678 total
includes taxes & fees
16 Sept - 17 Sept
Decapolis Hotel Panama City
Spa

4. The Hub by Boutique Apartments

The Hub by Boutique Apartments
3.0 star property
San Francisco
The price is Rp931.560
Rp3.331.436 total
includes taxes & fees
10 Sept - 11 Sept
The Hub by Boutique Apartments
Executive Suite, 1 King Bed, Partial Ocean View | Bathroom

5. JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,001 reviews)
  • cleanliness
    Immerse in waterfront tranquility with bay views, rejuvenating in-room massages, and four outdoor pools for a complete spa getaway.
The price is Rp4.670.221
Rp5.137.244 total
includes taxes & fees
20 Sept - 21 Sept
JW Marriott Panama
Jetted bathtub

6. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,108 reviews)
  • cleanliness
    Rejuvenating spa sanctuary with indoor pool offers daily pampering in Panama's central district.
The price is Rp3.050.016
Rp3.355.036 total
includes taxes & fees
30 Aug - 31 Aug
Las Americas Golden Tower Panama
Spa

7. Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very good, (1,702 reviews)
  • cleanliness
    Immerse in therapeutic bliss with 2 spa rooms, steam, and sauna at this full-service wellness hotel.
The price is Rp3.479.144
Rp3.827.058 total
includes taxes & fees
3 Sept - 4 Sept
Megapolis Hotel Panamá
Pool

8. Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (3 reviews)
The price is Rp1.466.009
Rp4.325.668 total
includes taxes & fees
21 Sept - 22 Sept
Wanders Panama by Boutique Apartments
Spa

9. Wanders & Yoo

Wanders & Yoo
4.0 star property
San Francisco
8.0 out of 10, Very good, (11 reviews)
Wanders & Yoo
Meeting facility

10. Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Luxurious spa retreat in the heart of Panama with 10 treatment rooms and pampering Ayurvedic services for a complete wellness journey.
The price is Rp2.750.320
Rp3.025.352 total
includes taxes & fees
30 Aug - 31 Aug
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in San Francisco

Pool
Breakfast included

Top San Francisco Hotel Reviews

Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

10/10 Excellent
"We had a great time at this resort. Food was delicious, service was great, pool was heated. We’ll definitely be back soon!"
Zhanna 6-night trip
Posted 6 hours ago
Dreams Playa Bonita Panama - All Inclusive
Decapolis Hotel Panama City

Decapolis Hotel Panama City

10/10 Excellent
"The property is excellent the fact that it’s connected to the mall and casino put it over the top. The staff are polite and always ready to assist you. Will definitely stay again."
Mark 4-night trip
Posted 7 hours ago
Decapolis Hotel Panama City

Frequently asked questions

Looking for a spa hotel in San Francisco?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Make sure you enjoy the many popular restaurants during your stay. Hotels with spas are a great way to take a break from your routine and add a layer of luxury to your weekend away.
What is the best spa hotel in San Francisco?
Megapolis Hotel Panamá is a top luxury spa hotel featuring 3 bars, a casino, a shopping centre and a fitness centre. Enjoy a facial, body scrub or detox wrap at the on-site spa. Other popular spa hotels in San Francisco include Decapolis Hotel Panama City and Las Americas Golden Tower Panama.
How many spa hotels will I find in San Francisco?
Among Expedia's 329 accommodation options in San Francisco, there are 5 spa hotels.
What's there to see and do in San Francisco?
Enjoy San Francisco and visit Multiplaza Pacific Mall, Calle 50 and Avenida Balboa. If you have spare time during your trip, you might want to make a stop at Multicentro Panama and Via Espana.
What is a San Francisco spa hotel?
Spa hotels in San Francisco provide lodging and have an on-site spa which offers services such as couples massages and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on holiday.