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Our top choices for Shands Jacksonville Medical Center hotels

55-inch LED TV with cable channels, TV, Netflix
Residence Inn by Marriott Jacksonville Downtown

Residence Inn by Marriott Jacksonville Downtown

Residence Inn by Marriott Jacksonville Downtown
3.0 star property
3 km from Shands Jacksonville Medical Center
9.6 out of 10, Exceptional, (356)
"Room was excellent and service was good"
United States
Satyanarayana
The price is Rp2.340.247
Rp2.656.180 total
includes taxes & fees
8 Jan - 9 Jan 2026
Residence Inn by Marriott Jacksonville Downtown
Daily buffet breakfast (USD 26.95 per person)
Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

Hyatt Regency Jacksonville
4.0 star property
Downtown Jacksonville, 2.8 km from Shands Jacksonville Medical Center
9.0 out of 10, Wonderful, (1406)
"Great stay "
United States
terria
The price is Rp2.719.656
Rp3.117.678 total
includes taxes & fees
31 Jan - 1 Feb 2026
Hyatt Regency Jacksonville
Basic Double Room | Free WiFi, bed sheets
Metro Inn & Suites

Metro Inn & Suites

Metro Inn & Suites
2.5 star property
Northwest, 2.1 km from Shands Jacksonville Medical Center
4.8 out of 10, (72)
"Great Stay !!! "
United States
Nydede
Metro Inn & Suites
Bar (on property)
Home2 Suites By Hilton Jacksonville Downtown

Home2 Suites By Hilton Jacksonville Downtown

Home2 Suites By Hilton Jacksonville Downtown
3.0 star property
3.4 km from Shands Jacksonville Medical Center
9.2 out of 10, Wonderful, (272)
"The place was easy to get to, the build your own breakfast sandwich station was fantastic. "
United States
Patrick
The price is Rp2.188.819
Rp2.484.310 total
includes taxes & fees
11 Jan - 12 Jan 2026
Home2 Suites By Hilton Jacksonville Downtown
View from property
Riverdale Inn

Riverdale Inn

Riverdale Inn
3.0 star property
4.2 km from Shands Jacksonville Medical Center
9.0 out of 10, Wonderful, (678)
"Amazing place, very quiet, clean, comfortable. The breakfast was super delicious. "
United States
Marcelo
The price is Rp2.602.140
Rp2.953.513 total
includes taxes & fees
1 Jan - 2 Jan 2026
Riverdale Inn
Property amenity
Holiday Inn Express & Suites Jacksonville W - I295 and I10 by IHG

Holiday Inn Express & Suites Jacksonville W - I295 and I10 by IHG

Holiday Inn Express & Suites Jacksonville W - I295 and I10 by IHG
2.5 star property
Northwest, 9.2 km from Shands Jacksonville Medical Center
9.4 out of 10, Exceptional, (491)
"Breakfast was great."
United States
Igor
The price is Rp1.962.207
Rp2.227.105 total
includes taxes & fees
10 Jan - 11 Jan 2026
Holiday Inn Express & Suites Jacksonville W - I295 and I10 by IHG
Exterior
Homewood Suites by Hilton Jacksonville Downtown-Southbank

Homewood Suites by Hilton Jacksonville Downtown-Southbank

Homewood Suites by Hilton Jacksonville Downtown-Southbank
3.0 star property
San Marco, 4.1 km from Shands Jacksonville Medical Center
8.6 out of 10, Excellent, (767)
"Older facility with a smell"
United States
Joanne
The price is Rp2.188.819
Rp2.484.309 total
includes taxes & fees
8 Jan - 9 Jan 2026
Homewood Suites by Hilton Jacksonville Downtown-Southbank
Property amenity
Courtyard by Marriott Jacksonville I-295/East Beltway

Courtyard by Marriott Jacksonville I-295/East Beltway

Courtyard by Marriott Jacksonville I-295/East Beltway
3.0 star property
Arlington, 11.5 km from Shands Jacksonville Medical Center
9.2 out of 10, Wonderful, (624)
"The room was immaculate. The staff was so friendly. The free cookies were awesome. I wish me and my husband could have stayed longer."
United States
Tamara
The price is Rp1.695.588
Rp1.924.492 total
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard by Marriott Jacksonville I-295/East Beltway
Outdoor pool
Tru by Hilton Jacksonville West I 295

Tru by Hilton Jacksonville West I 295

Tru by Hilton Jacksonville West I 295
3.0 star property
Northwest, 9.5 km from Shands Jacksonville Medical Center
9.0 out of 10, Wonderful, (206)
"Súper clean hotel, very helpful staff"
United States
Otto
The price is Rp1.638.173
Rp1.859.327 total
includes taxes & fees
9 Jan - 10 Jan 2026
Tru by Hilton Jacksonville West I 295
Lobby
TownePlace Suites Jacksonville Airport

TownePlace Suites Jacksonville Airport

TownePlace Suites Jacksonville Airport
3.5 star property
Northside, 15.1 km from Shands Jacksonville Medical Center
9.6 out of 10, Exceptional, (315)
"My stay was very comfortable and the staff was very nice "
United States
Patricia
The price is Rp2.333.532
Rp2.648.558 total
includes taxes & fees
1 Jan - 2 Jan 2026
TownePlace Suites Jacksonville Airport
Daily cooked-to-order breakfast for a fee
Hilton Garden Inn Jacksonville Downtown Southbank

Hilton Garden Inn Jacksonville Downtown Southbank

Hilton Garden Inn Jacksonville Downtown Southbank
3.0 star property
San Marco, 4.1 km from Shands Jacksonville Medical Center
8.4 out of 10, Very good, (1005)
"The hotel es very nice & very well located near the San Marco arear. "
United States
Julio
The price is Rp1.795.000
Rp2.037.324 total
includes taxes & fees
5 Jan - 6 Jan 2026
Hilton Garden Inn Jacksonville Downtown Southbank
Studio, 2 Queen Beds, Accessible, Non Smoking | Living area | 43-inch LCD TV with satellite channels, TV
Hampton Inn & Suites Jacksonville Deerwood Park

Hampton Inn & Suites Jacksonville Deerwood Park

Hampton Inn & Suites Jacksonville Deerwood Park
2.5 star property
Southside, 13.8 km from Shands Jacksonville Medical Center
9.4 out of 10, Exceptional, (1001)
"Great stay"
United States
Mary Jean
The price is Rp1.911.559
Rp2.169.619 total
includes taxes & fees
10 Jan - 11 Jan 2026
Hampton Inn & Suites Jacksonville Deerwood Park
Lobby
Southbank Hotel by Marriott Jacksonville Riverwalk

Southbank Hotel by Marriott Jacksonville Riverwalk

Southbank Hotel by Marriott Jacksonville Riverwalk
3.5 star property
Southbank, 3.6 km from Shands Jacksonville Medical Center
8.2 out of 10, Very good, (1627)
"Always a great stay"
United States
Ginger
The price is Rp1.722.449
Rp1.954.980 total
includes taxes & fees
11 Jan - 12 Jan 2026
Southbank Hotel by Marriott Jacksonville Riverwalk
Standard Double Room, 2 Double Beds, Smoking | Premium bedding, down duvets, in-room safe, blackout curtains
San Marco Inn East

San Marco Inn East

San Marco Inn East
3.0 star property
7.1 km from Shands Jacksonville Medical Center
8.4 out of 10, Very good, (1302)
"Good stay, room clean "
United States
Alfonso
San Marco Inn East
Exterior
Hotel Indigo Jacksonville-Deerwood Park by IHG

Hotel Indigo Jacksonville-Deerwood Park by IHG

Hotel Indigo Jacksonville-Deerwood Park by IHG
3.5 star property
Southside, 14.7 km from Shands Jacksonville Medical Center
9.2 out of 10, Wonderful, (1002)
"Very nice stay "
United States
Timmothy
The price is Rp1.913.832
Rp2.172.198 total
includes taxes & fees
3 Jan - 4 Jan 2026
Hotel Indigo Jacksonville-Deerwood Park by IHG
Desk, laptop workspace, blackout curtains, iron/ironing board
Candlewood Suites Jacksonville Southpoint by IHG

Candlewood Suites Jacksonville Southpoint by IHG

Candlewood Suites Jacksonville Southpoint by IHG
2.5 star property
Southpoint, 12.8 km from Shands Jacksonville Medical Center
9.0 out of 10, Wonderful, (302)
"Had a good stay ! "
United States
Martiyanna
The price is Rp1.626.757
Rp1.846.370 total
includes taxes & fees
2 Jan - 3 Jan 2026
Candlewood Suites Jacksonville Southpoint by IHG
Lobby
Hyatt Place Jacksonville Airport

Hyatt Place Jacksonville Airport

Hyatt Place Jacksonville Airport
3.0 star property
Northside, 14.6 km from Shands Jacksonville Medical Center
9.0 out of 10, Wonderful, (2309)
"Nice and clean hotel, good breakfast, had a comfortable stay."
United States
Krishna
The price is Rp1.844.810
Rp2.093.859 total
includes taxes & fees
25 Jan - 26 Jan 2026
Hyatt Place Jacksonville Airport
Meeting facility
Hilton Garden Inn Jacksonville JTB/Deerwood Park

Hilton Garden Inn Jacksonville JTB/Deerwood Park

Hilton Garden Inn Jacksonville JTB/Deerwood Park
3.0 star property
Southside, 14.4 km from Shands Jacksonville Medical Center
9.0 out of 10, Wonderful, (1008)
"Great place "
United States
Michael
The price is Rp1.775.835
Rp2.015.573 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hilton Garden Inn Jacksonville JTB/Deerwood Park
Terrace/patio
Tru by Hilton Jacksonville Airport I-95

Tru by Hilton Jacksonville Airport I-95

Tru by Hilton Jacksonville Airport I-95
2.5 star property
Northside, 15.1 km from Shands Jacksonville Medical Center
9.4 out of 10, Exceptional, (885)
"Good restaurant nearby. Very clean and comfortable room."
United States
Paula
The price is Rp1.683.501
Rp1.910.810 total
includes taxes & fees
11 Jan - 12 Jan 2026
Tru by Hilton Jacksonville Airport I-95
Terrace/patio
Aloft Jacksonville Tapestry Park

Aloft Jacksonville Tapestry Park

Aloft Jacksonville Tapestry Park
3.0 star property
Southside, 14.4 km from Shands Jacksonville Medical Center
9.0 out of 10, Wonderful, (1002)
"Clean room and nice staff"
United States
Shaquon
The price is Rp2.098.500
Rp2.381.797 total
includes taxes & fees
4 Jan - 5 Jan 2026
Aloft Jacksonville Tapestry Park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Shands Jacksonville Medical Center Hotel Reviews

Hotels near other Shands Jacksonville Medical Center attractions

Ritz Theatre & LaVilla Museum

You can spend an afternoon studying the exhibits at Ritz Theatre & LaVilla Museum during your travels in Jacksonville. Amble around this vibrant area's riverfront or experience its lively festivals.
See properties

UF Health Proton Therapy Institute

If UF Health Proton Therapy Institute is what brings you to town, hopefully you'll have a chance to explore more of Jacksonville.
See properties

Frequently asked questions

What's the area like around Shands Jacksonville Medical Center?
Shands Jacksonville Medical Center is located in a vibrant area of Jacksonville known for its stunning river views and sporting events. If you're looking for a convenient place to stay, take a look at the 128 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Shands Jacksonville Medical Center?
Hyatt Regency Jacksonville is one of the top choices for your stay based on our traveller data, and this hotel offers 3 restaurants and an outdoor pool. It's located 1.8 mi (2.8 km) from Shands Jacksonville Medical Center. Other good choices within a few miles include DoubleTree by Hilton Hotel Jacksonville Riverfront and Southbank Hotel by Marriott Jacksonville Riverwalk.
How many hotels can I expect to find near Shands Jacksonville Medical Center?
Expedia has 128 hotels and other accommodation options within a mile from Shands Jacksonville Medical Center.
If I need to cancel the hotel reservation for my stay near Shands Jacksonville Medical Center, will I receive a refund?
Yes! Most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to review the top deals on offer near Shands Jacksonville Medical Center.
What can I see and do near Shands Jacksonville Medical Center?
Jacksonville Museum of Modern Art, Cummer Museum of Art and Gardens and Ritz Theatre & LaVilla Museum feature captivating exhibits. While you're exploring, swing by Prime F. Osborn III Convention Center, Florida Theatre and Edwin Stanton School to learn a bit about the area. You can catch a show at Jacksonville Symphony Orchestra, Times-Union Center for the Performing Arts and Daily's Place.
How can I get to Shands Jacksonville Medical Center?
You can walk to nearby metro stations including Rosa Parks Station, James Weldon Johnson Park Station and Jacksonville Central Station. If you'd like to venture farther outside of the area, you may want a car rental for your journey.